amobarbital has been researched along with Necrosis in 6 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drug-metabolizing capacity has been assessed by serial measurements of the plasma antipyrine half life in 11 patients with severe barbiturate intoxication and in 17 patients with acute hepatic necrosis due to paracetamol overdosage." | 3.65 | Abnormal drug metabolism after barbiturate and paracetamol overdose. ( Forrest, JA; Prescott, LF; Roscoe, P; Stevenson, IH, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schaffer, SW | 1 |
| Croft, CB | 1 |
| Solodushko, V | 1 |
| Humphrey, SM | 1 |
| Vanderwee, MA | 1 |
| Forrest, JA | 1 |
| Roscoe, P | 1 |
| Prescott, LF | 2 |
| Stevenson, IH | 1 |
| Wrights, N | 1 |
| Mandy, S | 1 |
| Ackerman, AB | 1 |
| Linton, AL | 1 |
| Adams, JH | 1 |
| Lawson, DH | 1 |
6 other studies available for amobarbital and Necrosis
| Article | Year |
|---|---|
Cardioprotective effect of chronic hyperglycemia: effect on hypoxia-induced apoptosis and necrosis.
Topics: Amobarbital; Animals; Apoptosis; bcl-Associated Death Protein; Calcium; Carrier Proteins; Chronic Di | 2000 |
Factors affecting the development of contraction band necrosis during reperfusion of the isolated isovolumic rat heart.
Topics: Amobarbital; Animals; Coronary Circulation; Coronary Disease; Heart Ventricles; Male; Microscopy, El | 1986 |
Abnormal drug metabolism after barbiturate and paracetamol overdose.
Topics: Acetaminophen; Adult; Aged; Alanine Transaminase; Amobarbital; Antipyrine; Barbiturates; Bilirubin; | 1974 |
Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.
Topics: Acetaminophen; Adolescent; Adult; Amobarbital; Aspartate Aminotransferases; Bilirubin; Chemical and | 1973 |
Characteristic traumatic skin lesions in drug-induced coma.
Topics: Adult; Amobarbital; Barbiturates; Biopsy; Blister; Coma; Erythema; Heroin; Humans; Male; Nalorphine; | 1970 |
Muscle necrosis and acute renal failure in carbon monoxide poisoning.
Topics: Acute Kidney Injury; Adult; Amobarbital; Carbon Monoxide Poisoning; Female; Humans; Imipramine; Musc | 1968 |