amobarbital has been researched along with Myocardial Infarction in 6 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amobarbital treatment immediately before ischemia was used to test the hypothesis that damage to mitochondrial respiration occurs mainly during ischemia and that protection of mitochondria during ischemia leads to decreased cardiac injury with reperfusion." | 1.33 | Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion. ( Chen, Q; Hoppel, CL; Lesnefsky, EJ; Moghaddas, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q | 1 |
| Moghaddas, S | 1 |
| Hoppel, CL | 1 |
| Lesnefsky, EJ | 1 |
| Buchtal, A | 1 |
| Hanson, GC | 1 |
| Peisach, AR | 1 |
| Calvert, A | 1 |
| Mitchell, AS | 1 |
| Sinclair, G | 1 |
| Hackett, TP | 1 |
| Cassem, NH | 1 |
| Dorra, M | 1 |
| Chierici, F | 1 |
| Artuso, P | 1 |
| Suriani, L | 1 |
1 review available for amobarbital and Myocardial Infarction
| Article | Year |
|---|---|
[Myocardial physiopathology: the excitation-contraction block. II. Experimental and clinical aspects].
Topics: Amobarbital; Animals; Atrial Fibrillation; Biological Transport; Calcium; Calcium Chloride; Cell Mem | 1968 |
2 trials available for amobarbital and Myocardial Infarction
| Article | Year |
|---|---|
A double-blind evaluation of diazepam and amylobarbitone in acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Amobarbital; Arrhythmias, Cardiac; Behavior; Clinical Trials as Topic; D | 1974 |
Reduction of anxiety in the coronary-care unit. A controlled double-blind comparison of chlordiazepoxide and amobarbital.
Topics: Adult; Aged; Amobarbital; Analgesics; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Coronary | 1972 |
3 other studies available for amobarbital and Myocardial Infarction
| Article | Year |
|---|---|
Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion.
Topics: Amobarbital; Animals; Citrate (si)-Synthase; Cytochromes; Cytochromes c; Electron Transport; Hydroge | 2006 |
Transcutaneous aortovelography. Potentially useful technique in management of critically ill patients.
Topics: Adult; Aged; Amobarbital; Aorta, Thoracic; Blood Flow Velocity; Cardiac Output; Female; Heart; Heart | 1976 |
[Clinical results of the use of a new drug association in heart diseases].
Topics: Acetates; Adult; Aged; Amobarbital; Angina Pectoris; Coronary Disease; Female; Humans; Male; Middle | 1970 |