amobarbital has been researched along with Muscle Contraction in 19 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this investigation, we compared iLTS scar-derived fibroblasts in patients with and without T2DM." | 1.62 | Characterization of Fibroblasts in Iatrogenic Laryngotracheal Stenosis and Type II Diabetes Mellitus. ( Davis, R; Ding, D; Hillel, AT; Lina, I; Motz, KM; Tsai, HW, 2021) |
| "Using isolated rat aortic strips (AS) and portal veins (PV), it was found that all of the barbiturates studied (thiopental, secobarbital, pentobarbital, amobarbital, phenobarbital, and barbital): a) inhibit development of spontaneous mechanical activity (vasomotion) in AS and PV in concentrations used to induce surgical anesthesia or concentrations used for anticonvulsive therapy; b) dose-dependent attenuate contractions induced by epinephrine and potassium (K+); c) cause non-competitive displacement of the dose-response curves of these vasoactive compounds; d) attenuate calcium (Ca++)-induced contractions of K+-depolarized AS and PV; e) rapidly relax drug-induced, as well as Ca++-induced, contractions of AS and PV." | 1.25 | Barbiturates and aortic and venous smooth-muscle function. ( Altura, BM; Altura, BT, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lina, I | 1 |
| Tsai, HW | 1 |
| Ding, D | 1 |
| Davis, R | 1 |
| Motz, KM | 1 |
| Hillel, AT | 1 |
| SCHAER, H | 1 |
| MARTIN, I | 1 |
| DAVIES, BM | 1 |
| Skoogh, BE | 1 |
| Sunagane, N | 1 |
| Uruno, T | 1 |
| Kubota, K | 1 |
| Beresford, R | 1 |
| Bills, GN | 1 |
| Fastier, FN | 1 |
| Milne, RJ | 1 |
| Altura, BT | 1 |
| Altura, BM | 1 |
| Lövgren, B | 1 |
| Hellstrand, P | 1 |
| Shaw, GG | 1 |
| Jöbsis, FF | 1 |
| Stainsby, WN | 1 |
| Liu, M | 1 |
| Siess, M | 1 |
| Hoffmann, PC | 1 |
| Valette, G | 2 |
| Leclair, MF | 2 |
| Usui, H | 1 |
| Osumi, S | 1 |
| Toda, N | 1 |
| Fujiwara, M | 1 |
| Lauersen, NH | 1 |
| Fuchs, F | 1 |
| Tresise, PC | 1 |
| Stenhouse, NS | 1 |
| Dorra, M | 1 |
| Shibata, S | 1 |
| Hollander, PB | 1 |
| Buniatian, HC | 1 |
| Hovhannissian, VS | 1 |
| Aprikian, GV | 1 |
1 review available for amobarbital and Muscle Contraction
| Article | Year |
|---|---|
[Myocardial physiopathology: the excitation-contraction block. II. Experimental and clinical aspects].
Topics: Amobarbital; Animals; Atrial Fibrillation; Biological Transport; Calcium; Calcium Chloride; Cell Mem | 1968 |
18 other studies available for amobarbital and Muscle Contraction
| Article | Year |
|---|---|
Characterization of Fibroblasts in Iatrogenic Laryngotracheal Stenosis and Type II Diabetes Mellitus.
Topics: Adult; Aged; Amobarbital; Biopsy; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cicatri | 2021 |
[CHRONOTROPIC EFFECTS OF 5-SODIUM (1,3-DIMETHYLBUTYL)-5-ETHYLBARBITURATE (CONVULSANT BARBITURATE)].
Topics: Amobarbital; Animals; Barbiturates; Central Nervous System Stimulants; Convulsants; Guinea Pigs; Mus | 1964 |
THE EFFECT OF SODIUM AMYTAL ON AUTONOMIC AND MUSCLE ACTIVITY IN PATIENTS WITH DEPRESSIVE ILLNESS.
Topics: Amobarbital; Autonomic Nervous System; Blood Pressure; Depression; Electromyography; Galvanic Skin R | 1965 |
Transmission through airway ganglia.
Topics: Amobarbital; Animals; Bronchi; Ferrets; Ganglia, Autonomic; In Vitro Techniques; Muscle Contraction; | 1983 |
Mechanism of relaxant action of papaverine. II. Differences between modes of relaxant effects of papaverine and amytal in guinea-pig taenia coli.
Topics: Amobarbital; Animals; Calcium; Calcium Radioisotopes; Guinea Pigs; In Vitro Techniques; Male; Muscle | 1983 |
Effects of 2,4-dinitrophenol amylobarbitone and certain other drugs on the rate of oxygen consumption and force of contraction of isolated curarized diaphragm muscle of the rat.
Topics: Amobarbital; Animals; Diaphragm; Dinitrophenols; Female; In Vitro Techniques; Kinetics; Muscle Contr | 1979 |
Barbiturates and aortic and venous smooth-muscle function.
Topics: Amobarbital; Animals; Aorta, Thoracic; Barbiturates; Calcium; Depression, Chemical; Dose-Response Re | 1975 |
Graded effects of oxygen and respiratory inhibitors on cell metabolism and spontaneous contractions in smooth muscle of the rat portal vein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amobarbital; Animals; Cyanides; Lactates; Muscle Cont | 1985 |
Some pharmacological properties of the polyamines spermine and spermidine--a re-appraisal.
Topics: Aerosols; Amobarbital; Animals; Behavior, Animal; Body Temperature; Depression, Chemical; Duodenum; | 1972 |
Oxidation of NADH during contractions of circulated mammalian skeletal muscle.
Topics: Amobarbital; Animals; Citric Acid Cycle; Dogs; Fluorometry; Glycolysis; Hypoxia; Ischemia; Lactates; | 1968 |
Inhibition of the mitochondrial respiratory chain in isolated atria--a comparison of rotenone and amytal.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amobarbital; Animals; Electrons; Energy Transfer; Guine | 1970 |
[Sensitizing action of metabolic inhibitors on the responses of isolated guinea pig ileum to the effects of acetylcholine, histamine, angiotensin and bradykinin].
Topics: Acetylcholine; Amobarbital; Angiotensin II; Animals; Antimetabolites; Antimycin A; Bradykinin; Cyani | 1973 |
[Cardiovascular effects of guaiacol glycerol ether mononicotinate].
Topics: Amobarbital; Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Dogs; Electrocardi | 1972 |
Experience with Shirodkar's operation and postoperative alcohol treatment.
Topics: Abortion, Threatened; Amobarbital; Delivery, Obstetric; Ethanol; Female; Fetal Death; Gestational Ag | 1973 |
A clinical and statistical study of the phases of electroplexy.
Topics: Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Amobarbital; Anesthesia, General; Atropi | 1973 |
[Effects of metabolic inhibitors on shortening of the latency time of isolated organ responses induced by various contracting agents].
Topics: Acetylcholine; Amobarbital; Animals; Antimetabolites; Antimycin A; Cyanides; Drug Interactions; Fema | 1973 |
Effects of amobarbital and sodium salicylate on the membrane potentials and mechanical activity of cardiac muscle.
Topics: Action Potentials; Amobarbital; Animals; Heart Atria; Membrane Potentials; Muscle Contraction; Rats; | 1968 |
The participation of N-acetyl-L-aspartic acid in brain metabolism.
Topics: Acetylcholine; Aminobutyrates; Amobarbital; Animals; Aspartic Acid; Brain; Caffeine; Glucose; In Vit | 1965 |