amobarbital has been researched along with Injuries, Spinal Cord in 2 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sodium amobarbital decreased spontaneous pain by 73% (vs 46% with lidocaine) and normalized sensory abnormalities at or above the level of injury in 3 patients (as compared to just 1 patient with lidocaine), 2 of whom had transitional zone allodynia/hyperalgesia." | 9.14 | Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury. ( Bharatwal, B; Krassioukov, AV; Mailis-Gagnon, A; Yegneswaran, B, 2009) |
| "Sodium amobarbital decreased spontaneous pain by 73% (vs 46% with lidocaine) and normalized sensory abnormalities at or above the level of injury in 3 patients (as compared to just 1 patient with lidocaine), 2 of whom had transitional zone allodynia/hyperalgesia." | 5.14 | Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury. ( Bharatwal, B; Krassioukov, AV; Mailis-Gagnon, A; Yegneswaran, B, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mailis-Gagnon, A | 1 |
| Yegneswaran, B | 1 |
| Bharatwal, B | 1 |
| Krassioukov, AV | 1 |
| Corbett, M | 1 |
| Frankel, HL | 1 |
| Michaelis, L | 1 |
2 trials available for amobarbital and Injuries, Spinal Cord
| Article | Year |
|---|---|
Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury.
Topics: Adult; Amobarbital; Anesthetics, Local; Female; Humans; Hypnotics and Sedatives; Injections, Intrave | 2009 |
A double blind, cross-over trial of Valium in the treatment of spasticity.
Topics: Amobarbital; Diazepam; Evaluation Studies as Topic; Female; Humans; Male; Muscle Spasticity; Placebo | 1972 |