amobarbital has been researched along with Idiopathic Parkinson Disease in 9 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute administration of tetrabenazine produced tremor in cats, in doses which caused sedation but not hypothermia." | 7.65 | Tremor induced by tetrabenazine. ( Calne, DB; Webster, RA, 1969) |
| " Acute administration of tetrabenazine produced tremor in cats, in doses which caused sedation but not hypothermia." | 3.65 | Tremor induced by tetrabenazine. ( Calne, DB; Webster, RA, 1969) |
| "As a major co-morbidity of Parkinson's disease (PD), depression is associated with the loss of serotonergic neurons." | 1.34 | Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism. ( Feng, J; Ren, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OBRADOR, S | 1 |
| CARRASCOSA, R | 1 |
| CARBONELL, J | 1 |
| ONUAGULUCHI, G | 1 |
| ALEMA, G | 1 |
| ROSADINI, G | 1 |
| ROSSI, GF | 1 |
| Winkler-Stuck, K | 1 |
| Wiedemann, FR | 1 |
| Wallesch, CW | 1 |
| Kunz, WS | 1 |
| Ren, Y | 1 |
| Feng, J | 1 |
| Kalow, W | 1 |
| Austin, G | 1 |
| Hayward, W | 1 |
| Tsai, C | 1 |
| Kuykendall, A | 1 |
| Calne, DB | 1 |
| Webster, RA | 1 |
| Leissner, P | 1 |
| Petersén, I | 1 |
| Sörbye, R | 1 |
1 review available for amobarbital and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Ethnic differences in reactions to drugs and xenobiotics. Conjugation reactions.
Topics: Acetaminophen; Amobarbital; Asian People; Canada; Catechol O-Methyltransferase; Ethnicity; Female; G | 1986 |
8 other studies available for amobarbital and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Study of some motor syndromes (rigidity, tremor, spasticity and hemidecortication) by the carotid amytal test.
Topics: Amobarbital; Humans; Movement Disorders; Muscle Rigidity; Muscle Spasticity; Neurology; Parkinson Di | 1961 |
Drug therapy in the crises of postencephalitic parkinsonism.
Topics: Amobarbital; Encephalitis; Encephalitis, Arbovirus; Humans; Parkinson Disease; Parkinson Disease, Po | 1961 |
[Preliminary experiments on the effects of the intracarotid introduction of sodium amytal in parkinsonian syndromes].
Topics: Amobarbital; Parkinson Disease; Parkinsonian Disorders | 1961 |
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients.
Topics: Adenosine Diphosphate; Adult; Aged; Amobarbital; Antioxidants; Cells, Cultured; Coenzymes; Drug Inte | 2004 |
Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism.
Topics: Amobarbital; Animals; Cell Death; Cells, Cultured; Colchicine; Electron Transport Complex I; Mesence | 2007 |
Parkinsonian tremor: soe aspects of an experimental model and its solution.
Topics: Amobarbital; Basal Ganglia; Computers, Analog; Electric Stimulation; Electromyography; Epinephrine; | 1965 |
Tremor induced by tetrabenazine.
Topics: Amobarbital; Animals; Body Temperature; Cats; Disease Models, Animal; Hot Temperature; Parkinson Dis | 1969 |
Chlormethiazole, amobarbital, lidocaine and PLT 101 in spasticity and rigidity: a study of clinical and EMG-Registrable effects on intravenous injection.
Topics: Adolescent; Adult; Aged; Amobarbital; Chlormethiazole; Electromyography; Female; Humans; Hypnotics a | 1969 |