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amobarbital and Hepatic Encephalopathy

amobarbital has been researched along with Hepatic Encephalopathy in 1 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
"The effects of rapid intracarotid injection of 20 to 100 mg of sodium amobarbital were studied in three patients with bilateral myoclonic status epilepticus due to Jakob-Creutzfeldt disease, sequelae to anoxic encephalopathy, and hepatic coma, respectively."7.65Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus. ( Chatrian, GE; McCutchen, CB; Vignaendra, V, 1977)
"The effects of rapid intracarotid injection of 20 to 100 mg of sodium amobarbital were studied in three patients with bilateral myoclonic status epilepticus due to Jakob-Creutzfeldt disease, sequelae to anoxic encephalopathy, and hepatic coma, respectively."3.65Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus. ( Chatrian, GE; McCutchen, CB; Vignaendra, V, 1977)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCutchen, CB1
Vignaendra, V1
Chatrian, GE1

Other Studies

1 other study available for amobarbital and Hepatic Encephalopathy

ArticleYear
Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus.
    Neurology, 1977, Volume: 27, Issue:3

    Topics: Aged; Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Creutzfeldt-Jakob Syndrome; Electroenc

1977