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amobarbital and Epilepsy, Temporal Lobe

amobarbital has been researched along with Epilepsy, Temporal Lobe in 189 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"Two patients with temporolimbic epilepsy considered to be surgical candidates referred for the intracarotid amobarbital sodium procedure (IAP)."7.68The association of multiple personality and temporolimbic epilepsy. Intracarotid amobarbital test observations. ( Ahern, GL; Herring, AM; Labiner, DM; Oommen, KJ; Seeger, JF; Tackenberg, J; Weinand, ME, 1993)
"Amobarbital was injected by transfemoral selective catheterization of the arteries supplying the target areas."5.30Selective amobarbital test for the determination of language function in patients with epilepsy with frontal and posterior temporal brain lesions. ( Buck, A; Hajek, M; Schiess, R; Valavanis, A; Wieser, HG; Yonekawa, Y, 1998)
"To assess the value of SPECT during intracarotid amobarbital procedure (IAP) to discriminate which patients performed the test with the hippocampus inactivated and correlate it with the risk of amnesia after anterior temporal lobectomy (ATL)."3.72Can the Wada test evaluate mesial temporal function? A SPECT study. ( Arroyo, S; Bargalló, N; Boget, T; Fuertes, S; Fuster, D; Lomeña, F; Pareto, D; Pavía, J; Pons, F; Rumià, J; Setoain, X, 2004)
"The aim of this study was to determine whether the predictive value of the intracarotid amobarbital test (IAT) for the side to be resected is applicable only to medial temporal lobe epilepsy and to investigate whether there are different patterns of memory performances on the IAT between patients with unilateral mesial temporal sclerosis (UMT group) and those without (non-UMT group)."3.70Lateralized memory deficits on the Wada test correlate with the side of lobectomy only for patients with unilateral medial temporal lobe epilepsy. ( Hayashi, K; Kakeuchi, J; Kanemoto, K; Kawasaki, J; Kubo, H; Morimura, T; Takenouchi, K, 1999)
"In a sample of 83 patients counterbalanced for side of temporal-lobe seizure focus, we examined unawareness of hemiplegia upon clearing of the deficit after bilateral sodium amobarbital injections."3.69Do intracarotid barbiturate injections offer a way to investigate hemispheric models of anosognosia? ( Dywan, CA; Fox, A; McGlone, J, 1995)
"Two patients with temporolimbic epilepsy considered to be surgical candidates referred for the intracarotid amobarbital sodium procedure (IAP)."3.68The association of multiple personality and temporolimbic epilepsy. Intracarotid amobarbital test observations. ( Ahern, GL; Herring, AM; Labiner, DM; Oommen, KJ; Seeger, JF; Tackenberg, J; Weinand, ME, 1993)
"Fifty-five percent had a history of febrile seizures."2.69Presurgical evaluation and surgical outcome of temporal lobe epilepsy. ( Asconape, J; Azzarelli, B; Garg, B; Hutchins, GD; Markand, O; Park, HM; Patel, H; Salanova, V; Smith, R; Worth, R, 1999)
"As amobarbital was no longer available, our aim was to validate propofol as an alternative."1.40Bilateral Wada test: amobarbital or propofol? ( Barragan-Jason, G; Busigny, T; Curot, J; Denuelle, M; Fabre, N; Kany, M; Marlat, F; Tall, P; Valton, L, 2014)
"We sought to determine whether hypersalivation helps lateralize seizure onset during complex partial seizures of temporal lobe origin."1.33Hypersalivation in temporal lobe epilepsy. ( Fuerst, D; Shah, J; Watson, C; Zhai, H, 2006)
"Amobarbital was distributed in the iMCA in all the patients; in the iACA in 20 (90."1.31Contralateral EEG slowing and amobarbital distribution in Wada test: an intracarotid SPECT study. ( Byun, HS; Hong, SB; Kim, KW; Kim, SE; Na, DG; Seo, DW, 2000)
"Four patients had nominal dysphasia for 1-3 min."1.31Posterior cerebral artery Wada test: sodium amytal distribution and functional deficits. ( Behrends, K; Biersack, HJ; Klemm, E; Linke, DB; Schild, HH; Schramm, J; Urbach, H, 2001)
"MRI-HS correlated with a history of febrile seizures and pathologically demonstrated hippocampal sclerosis."1.30FDG-PET and MRI in temporal lobe epilepsy: relationship to febrile seizures, hippocampal sclerosis and outcome. ( Azzarelli, B; Ghetti, B; Hutchins, G; Markand, O; Park, H; Salanova, V; Smith, R; Wellman, H; Worth, R, 1998)
"Amobarbital was injected by transfemoral selective catheterization of the arteries supplying the target areas."1.30Selective amobarbital test for the determination of language function in patients with epilepsy with frontal and posterior temporal brain lesions. ( Buck, A; Hajek, M; Schiess, R; Valavanis, A; Wieser, HG; Yonekawa, Y, 1998)
"Two persons with Global Amnesia obtained scores at or below chance (i."1.30Criterion-based validity of an intracarotid amobarbital recognition-memory protocol. ( Black, SE; Evans, J; McGlone, J; Parkin, A; Sadler, M; Sita, A; Squires, E; Stuss, D; Wilson, BA, 1999)

Research

Studies (189)

TimeframeStudies, this research(%)All Research%
pre-199021 (11.11)18.7374
1990's74 (39.15)18.2507
2000's78 (41.27)29.6817
2010's12 (6.35)24.3611
2020's4 (2.12)2.80

Authors

AuthorsStudies
Kaestner, E1
Pedersen, NP1
Hu, R1
Vosoughi, A1
Alwaki, A1
Ruiz, AR1
Staikova, E1
Hewitt, KC1
Epstein, C1
McDonald, CR1
Gross, RE1
Drane, DL2
Conradi, N1
Rosenberg, F1
Biermann, L1
Haag, A2
Hermsen, A1
Gorny, I1
von Podewils, V1
Gurschi, M1
Keil, F1
Hattingen, E1
Menzler, K1
Bauer, S1
Schubert-Bast, S1
Knake, S2
Rosenow, F2
Strzelczyk, A1
Qadri, S1
Dave, H1
Das, R1
Alick-Lindstrom, S1
Lozano-García, A1
Hampel, KG1
Garcés-Sánchez, M1
Aparici-Robles, F1
Rubio-Sánchez, P1
González-Bono, E1
Cano-López, I1
Villanueva, V1
Massot-Tarrús, A1
Mousavi, SR1
Mirsattari, SM1
Janecek, JK1
Winstanley, FS2
Sabsevitz, DS2
Raghavan, M1
Mueller, W1
Binder, JR1
Swanson, SJ2
Yılmaz, NH1
Bingol, AP1
Curot, J1
Denuelle, M1
Busigny, T1
Barragan-Jason, G1
Kany, M1
Tall, P1
Marlat, F1
Fabre, N1
Valton, L1
Loring, DW11
Gaillard, WD1
Bookheimer, SY1
Meador, KJ7
Ojemann, JG1
Papanicolaou, AC2
Rezaie, R1
Narayana, S1
Choudhri, AF1
Wheless, JW2
Castillo, EM2
Baumgartner, JE1
Boop, FA2
Połczyńska, M1
Curtiss, S1
Walshaw, P1
Siddarth, P1
Benjamin, C1
Moseley, BD1
Vigil, C1
Jones, M1
Eliashiv, D1
Bookheimer, S1
Mani, J1
Busch, R2
Kubu, C1
Kotagal, P3
Shah, U1
Dinner, D2
Testa, SM1
Ward, J1
Crone, NE2
Brandt, J1
Uijl, SG1
Leijten, FS1
Arends, JB1
Parra, J1
van Huffelen, AC1
van Rijen, PC2
Moons, KG1
Suarez, RO1
Whalen, S1
Nelson, AP1
Tie, Y1
Meadows, ME1
Radmanesh, A1
Golby, AJ2
Rathore, C1
George, A1
Kesavadas, C1
Sarma, PS1
Radhakrishnan, K1
Elshorst, N1
Pohlmann-Eden, B1
Horstmann, S2
Schulz, R2
Woermann, F1
McAndrews, MP1
Engel, J3
McDermott, MP1
Wiebe, S1
Langfitt, JT1
Erba, G1
Gardiner, I1
Stern, J1
Dewar, S1
Sperling, MR4
Jacobs, M1
Kieburtz, K1
Das, RR1
Alexopoulos, AV1
Loddenkemper, T2
Banks, S1
Sziklas, V1
Djordjevic, J1
Golinski, R1
Jones-Gotman, M2
Adamolekun, B1
Afra, P1
Carvajal-Castrillón, J1
Zapata, J1
Galeano-Toro, LM1
Bareño, J1
Jiménez, M1
Poldrack, RA1
Illes, J1
Chen, D1
Desmond, JE2
Gabrieli, JD2
Baxendale, S3
Maestú, F1
Ortiz, T1
Fernandez, A1
Amo, C1
Martin, P1
Fernández, S1
Sola, RG1
Rutten, GJ1
Ramsey, NF1
Alpherts, WC2
van Veelen, CW2
Liégeois, F1
Connelly, A2
Salmond, CH1
Gadian, DG1
Vargha-Khadem, F1
Baldeweg, T1
Foldvary, N2
Raja, S1
Neme, S1
Lüders, HO3
Sabbah, P1
Chassoux, F1
Leveque, C1
Landre, E1
Baudoin-Chial, S1
Devaux, B1
Mann, M1
Godon-Hardy, S1
Nioche, C1
Aït-Ameur, A1
Sarrazin, JL1
Chodkiewicz, JP1
Cordoliani, YS1
Akanuma, N2
Alarcón, G2
Lum, F1
Kissani, N2
Koutroumanidis, M3
Adachi, N4
Binnie, CD3
Polkey, CE5
Morris, RG5
Stroup, E1
Langfitt, J1
Berg, M1
McDermott, M1
Pilcher, W1
Como, P1
Lee, GP8
Park, YD1
Westerveld, M2
Hempel, A1
Blackburn, LB1
Hamer, HM2
Dittmer, C1
Bien, S1
Oertel, WH1
Holmes, MD1
Miles, AN1
Dodrill, CB2
Ojemann, GA2
Wilensky, AJ1
Gramstad, A1
Engelsen, BA1
Hugdahl, K1
DAVISON, K1
PEREZ-BORJA, C1
RIVERS, MH1
Bramham, J1
Lacruz, ME1
Lum, FC1
Kipervasser, S2
Andelman, F4
Kramer, U1
Nagar, S1
Fried, I4
Neufeld, MY3
Szaflarski, JP1
Holland, SK1
Schmithorst, VJ1
Dunn, RS1
Privitera, MD2
Smith, JR4
Deblaere, K1
Boon, PA1
Vandemaele, P1
Tieleman, A1
Vonck, K3
Vingerhoets, G3
Backes, W1
Defreyne, L1
Achten, E1
Setoain, X1
Arroyo, S1
Lomeña, F1
Pavía, J1
Pareto, D1
Boget, T1
Bargalló, N1
Rumià, J1
Fuster, D1
Fuertes, S1
Pons, F1
Stabell, KE1
Bakke, SJ1
Andresen, S1
Bjørnaes, H1
Borchgrevink, HM1
Due-Tønnessen, P1
Heminghyt, E1
Nome, T1
Pedersen, HK1
Ramm-Pettersen, J1
Røste, GK1
Tennøe, B1
de Paola, L1
Mäder, MJ1
Germiniani, FM1
Coral, P1
Zavala, JA1
Watzo, DJ1
Kanegusuku, J1
Silvado, CE1
Werneck, LC1
Jabbour, RA1
Penovich, PE1
Risse, GL1
Kispert, DE1
Dunn, MB1
Gates, JR2
Lee, JS1
Lee, DS3
Kim, YK1
Kim, J1
Lee, HY1
Lee, SK3
Chung, JK1
Lee, MC1
Pataraia, E1
Billingsley-Marshall, RL1
Breier, JI2
Simos, PG1
Sarkari, S1
Fitzgerald, M1
Clear, T1
Benke, T2
Chemelli, A2
Lottersberger, C1
Waldenberger, P1
Karner, E2
Trinka, E2
Jokeit, H3
Woermann, FG1
Ebner, A2
Kirsch, HE1
Walker, JA2
Hendrickson, R1
Wong, ST1
Barbaro, NM2
Laxer, KD1
Garcia, PA2
Kim, MA1
Heo, K1
Choo, MK1
Cho, JH1
Park, SC1
Lee, JD1
Yun, M1
Park, HJ1
Lee, BI1
Miatton, M2
Seurinck, R2
Boon, P2
Yen, DJ2
Lirng, JF1
Shih, YH1
Shan, IK1
Su, TP1
Chen, C1
Yu, HY1
Yiu, CH2
Shah, J1
Zhai, H1
Fuerst, D1
Watson, C1
Anderson, DP1
Harvey, AS1
Saling, MM1
Anderson, V1
Kean, M1
Abbott, DF1
Wellard, RM1
Jackson, GD1
Köylü, B1
Visani, P1
Brenneis, C1
Bartha, L1
Trieb, T1
Felber, S1
Bauer, G1
Willmes, K1
Cheung, MC1
Chan, AS1
Chan, YL1
Lam, JM1
Lam, W1
Kaiboriboon, K1
Parent, JM1
Boatman, DF1
Lesser, RP3
Krauss, G1
Lenz, FA1
Miglioretti, DL1
Reider-Groswasser, II1
Pauli, E2
Hildebrandt, M1
Romstöck, J1
Stefan, H2
Blümcke, I1
Chlebus, P1
Mikl, M1
Brázdil, M1
Pazourková, M1
Krupa, P1
Rektor, I1
Thompson, P1
Harkness, W1
Duncan, J1
Keary, TA1
Frazier, TW1
Busch, RM1
Kubu, CS2
Iampietro, M1
Burton, DB1
Pereira, E1
Modur, PN1
Ramirez, MJ1
Schefft, BK1
Howe, SR1
Hwa-Shain, Y1
Kim, JH2
Joo, EY1
Han, SJ1
Cho, JW1
Lee, JH1
Seo, DW4
Hong, SB4
Haber, AH1
Vassallo, JL1
Tatum, WO1
Benbadis, SR2
Asadi-Pooya, AA1
Penide, C1
Penide, L1
Pumar, JM1
Vulliemoz, S1
Pegna, AJ1
Annoni, JM1
Yilmaz, H1
Willi, JP1
Spinelli, L1
Landis, T1
Seeck, M1
Thompson, PJ2
Duncan, JS2
Jehi, LE1
Naugle, R1
Ruggieri, P1
Morris, H1
Wyllie, E2
Bingaman, B1
Prayson, R1
Diehl, B1
Alexopoulos, A1
Bautista, J1
Dupont, S1
Oxbury, SM1
Oxbury, JM1
Silfvenius, H7
Blom, S1
Nilsson, LG2
Christianson, SA5
Rausch, R3
Fedio, P2
Ary, CM1
Crandall, PH2
Wale, J1
Geffen, G1
Lieb, JP1
Kuhl, DE1
So, NK1
Antar, MA1
Barnett, GH1
Morris, HH3
Dywan, CA1
McGlone, J2
Fox, A1
Flanigin, HF3
Saykin, AJ3
Glosser, G5
Moran, M1
French, JA3
Brooks, M1
O'Connor, MJ2
Kurthen, M8
Helmstaedter, C2
Linke, DB8
Hufnagel, A3
Elger, CE6
Schramm, J3
Verma, NP1
Rangnathan, C1
Fuerst, DR1
Ahern, GL1
Herring, AM1
Tackenberg, J1
Seeger, JF1
Oommen, KJ1
Labiner, DM1
Weinand, ME1
Säisä, J3
Garvill, J1
Onuma, T2
Suzuki, I2
Shimizu, H2
Ishijima, B2
Perrine, K5
Gershengorn, J3
Brown, ER1
Choi, IS1
Luciano, DJ2
Devinsky, O4
O'Rourke, DM1
Gilhool, JJ1
Harley, R1
Trenerry, MR1
Caner-Cukiert, AR1
Cukiert, A1
Gronich, G1
Marino Júnior, R1
Sum, JM1
Wagner, AD1
Demb, JB1
Shear, PK1
Glover, GH1
Morrell, MJ2
Su, MS1
Kwan, SY1
Tsai, CP1
Lin, YY1
Ebersole, JS1
Pacia, SV1
Privitera, M1
Kohler, C1
Cahill, W1
Yeh, HS1
Weissenborn, K2
Rückert, N2
Brassel, F3
Becker, H2
Dietz, H1
Hussein, S1
Hamberger, MJ2
Walczak, TS1
Goodman, RR1
Morton, N1
Cox, T1
Roman, DD1
Beniak, TE1
Nugent, S1
Hermann, BP2
Plenger, PM2
Ravdin, LD1
Haywood, CS1
Nelson, PK3
MacDonald, K1
Nichols, ME1
Moore, EE1
Figueroa, RE1
Dade, LA1
Rouleau, I2
Robidoux, J1
Labrecque, R2
Denault, C1
Kneebone, AC1
Chelune, GJ1
Yoon, BW1
Morillo, CA1
Cechetto, DF1
Hachinski, V1
Acharya, JN1
Dinner, DS2
Sass, KJ1
Silberfein, CM1
Platis, I1
Buchanan, CP1
Delaney, RC1
Spencer, DD1
Gleissner, U1
Khan, N1
Hajek, M2
Antonini, A1
Maguire, P1
Müller, S1
Valavanis, A2
Leenders, KL1
Regard, M1
Schiess, R2
Wieser, HG2
Kim, H1
Yi, S1
Lancman, ME1
Benbadis, S1
Geller, E1
Salanova, V3
Markand, O3
Worth, R3
Smith, R2
Wellman, H1
Hutchins, G1
Park, H1
Ghetti, B1
Azzarelli, B2
Donofrio, N2
Yonekawa, Y1
Buck, A1
Thomas, AB1
Brookshire, BL1
Papanicolaou, A1
Willmore, LJ1
Baxendale, SA1
Van Paesschen, W1
Shorvon, SD1
Gerschlager, W1
Lalouschek, W1
Lehrner, J1
Baumgartner, C1
Lindinger, G1
Lang, W1
Na, DL1
Adair, JC1
Kim, GM1
Heilman, KM1
Deutsch, GK2
Cole, LC2
Corwin, J1
Swearer, JM1
Kane, KJ1
Phillips, CA1
Weaver, JP1
Anderson, TD1
Lavoie, MS1
Davies, KG2
Bell, BD2
Dohan, FC1
Schweitzer, JB1
Garg, B1
Patel, H1
Asconape, J1
Park, HM1
Hutchins, GD1
Kim, BG1
Nam, HW1
Song, HC1
Black, SE1
Evans, J1
Parkin, A1
Sadler, M1
Sita, A1
Squires, E1
Stuss, D1
Wilson, BA1
de Silva, R1
Duncan, R1
Patterson, J1
Gillham, R1
Hadley, D1
Bagley, L1
Baltuch, G1
Urbach, H3
Klemm, E3
Grunwald, T1
Van Roost, D1
Biersack, HJ5
Hirsch, LJ1
von Manitius-Robeck, S1
Markowitsch, HJ1
Killgore, WD1
Casasanto, DJ1
Alsop, DC1
Detre, JA1
Son, YJ1
Chung, CK1
Chang, KH1
Yi, YN1
Kim, HJ1
Kanemoto, K1
Kawasaki, J1
Takenouchi, K1
Hayashi, K1
Kubo, H1
Morimura, T1
Kakeuchi, J1
Corcia, P1
De Toffol, B1
Hommet, C1
Autret, A1
Kim, KW1
Kim, SE2
Na, DG1
Byun, HS1
Spencer, DC1
Risinger, MW1
Vermeulen, J1
Stanford, L1
Mascha, E1
Wolgamuth, B1
Hennessy, MJ1
Seed, PT1
Elwes, RD1
Jarosz, J1
Maisey, MN1
Noerpel, I1
Herbord, E1
Neufeld, M1
Reider-Groswasser, I1
Kremer, U1
Segev, Y1
McCabe, PH1
Eslinger, PJ1
Tatlidil, R1
Xiong, J1
Luther, S1
Masters, LT1
Haltiner, AM1
Walters, GL1
Girvin, JP1
McLachlan, RS1
Pavol, M1
Harnadek, MC1
von Oertzen, J1
de Greiff, A1
Roh, SY1
Behrends, K1
Schild, HH1
Chiaravalloti, ND1
Morris, GL1
Mueller, WM1
Seidenberg, M1
Gloor, P1
King, DW2
Böker, DK1
Solymosi, L2
Reuter, BM3
Friedman, D1
Jeffery, PJ1
Monsein, LH1
Szabo, Z1
Hart, J1
Fisher, RS1
Debrun, GM1
Gordon, B1
Wagner, HN1
Camargo, EE1
Cruz-Rodriguez, R1
Murro, AM1
Gallagher, BB1
Sugishita, M1
Reichmann, K2
Durwen, HF2
Grünwald, F1
Hietala, SO1
Aasly, J2
Olivecrona, M1
Jonsson, L1
Ross, ED1
Edmondson, JA1
Seibert, GB1
Homan, RW1
Saint-Hilaire, JM1
Cardu, B1
Giard, N1
Zatorre, RJ1
Jack, CR2
Nichols, DA2
Sharbrough, FW2
Marsh, WR2
Petersen, RC2
Hinkeldey, NS1
Ivnik, RJ1
Cascino, GD1
Ilstrup, DM1
Zetterlund, B1
Wappenschmidt, J1
Miller, DL1
Powell, GE1
Canavan, AG1
Lüders, H1
Milner, B1
Lloyd-Smith, DL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Memantine Improve Verbal Memory Task Performance in Subjects With Localization-related Epilepsy and Memory Dysfunction? A Randomized, Double-Blind, Placebo-Controlled Trial[NCT01054599]29 participants (Actual)Interventional2009-01-31Completed
Cognitive Effects of Treatment of Interictal Discharges[NCT00916149]31 participants (Actual)Interventional2007-01-31Completed
Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy[NCT00001672]40 participants Observational1997-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

A Secondary Analysis Will Examine the Possible Sustained Benefit of Continued Memantine Use.

SRT-CLTR (range 0-72; higher scores indicate better memory), and 7-24 Spatial Memory Test (range 0-35; scores are summed across the 5 learning trials, with higher scores indicating better memory) scores will be assessed across the first (baseline) and third (post-open label memantine) testing sessions. These measures are considered to be scores on a scale, rather than standard units. The hypothesis was that subjects randomized to memantine would demonstrate sustained improvement from baseline, while the placebo group would demonstrate improvements after taking open label memantine (compared to baseline). (NCT01054599)
Timeframe: 26 weeks

,
Interventionscores on a scale (Mean)
SRT CLTR BaselineSRT CLTR Post-Open Label7-24 Total Learning Baseline7-24 Total Learning Post-Open Label
Memantine32.6740.3330.3331.67
Sugar Pill22.7140.2928.1432.43

The Change Scores in Memory Measures From Baseline to Post-treatment/Placebo Will be Compared Between the Memantine Treatment and Placebo Groups.

Change scores from pre- to post-treatment/placebo were calculated for the primary outcome measures, the Selective Reminding Test Continuous Long-Term Retrieval (range 0-72; higher scores indicate better memory) and 7-24 Spatial Recall Test Total Learning (range 0-35; total correct across 5 learning trials are summed, with higher scores indicating better memory) scores. These measures are scores on a scale, rather than representing standard units. (NCT01054599)
Timeframe: 13 weeks

,
Interventionscores on a scale (Mean)
7-24 Spatial Recall Tests Learning Change ScoreSRT Continuous Long-Term Retrieval Change Score
Memantine1.004.38
Sugar Pill1.788.11

Mean Change in Focal Interictal Discharges (IEDs) Per Hour, Pre to Post Treatment

This descriptive analysis examined the change in interictal discharge rates pre to post-treatment with levetiracetam in subjects with epilepsy and with no treatment in healthy controls. (NCT00916149)
Timeframe: 1 and 11 weeks

InterventionIEDs/hour (Mean)
No Treatment-28.8
Levetiracetam.54

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Adverse Events Profile (AEP)

Change in Adverse Events Profile score (scores range from 19-76; higher scores indicate greater side effects) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment-1.27
Levetiracetam1

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: BVMT-R Delayed Recall

Change in Brief Visuospatial Memory Test-Revised (BVMT-R) Delayed Recall score (the score ranges from 0-6, reflecting the number of shapes recalled after a 25 minute delay) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment.36
Levetiracetam.33

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: BVMT-R Learning

Change in Brief Visuospatial Memory Test-Revised (BVMT-R) Learning score (the score ranges from 0-6, reflecting the number of shapes recalled on the initial learning trial) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment.45
Levetiracetam.33

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: BVMT-R Total Learning

Change in Brief Visuospatial Memory Test-Revised (BVMT-R) Total Learning score (the score is summed across 3 learning trials, score range 0-18, reflecting the total number of shapes recalled) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment1.09
Levetiracetam.17

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Choice Accuracy

Change in Choice Accuracy Score (indicate if red or blue stimulus; accuracy 0-100%) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment.02
Levetiracetam.1

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Choice Reaction Time

Change in Choice Reaction Time Score, with reaction time measured in seconds (indicate if red or blue stimulus; lower reaction time suggests better performance) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment34.96
Levetiracetam.45

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CPT Accuracy

Change in Continuous Performance Test Score - Accuracy (CPT; score ranges from 0-100% correct) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment-0.01
Levetiracetam.01

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CPT Reaction Time (CPT RT)

Change in Continuous Performance Test Score - Reaction Time, measured in seconds (CPT RT; less time reflects better performance) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment1.04
Levetiracetam-11.33

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CVLT Long Delay

Change in California Verbal Learning Test (CVLT) Long Delay Recall score (the score ranges from 0-16, reflecting the number of words recalled) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment1.55
Levetiracetam2.67

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CVLT Short Delay

Change in California Verbal Learning Test (CVLT) Short Delay Recall Score (the score ranges from 0-16, reflecting the number of words recalled) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment1.27
Levetiracetam-0.4

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CVLT Total Learning

Change in California Verbal Learning Test (CVLT) Total Learning Score (the total learning score is summed across 5 learning trials, range 0-80). Higher scores indicate better memory. Scores on the CVLT reflect the number of words recalled. (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment8.09
Levetiracetam5.5

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: CVLT Trial 1 Learning Score

Change in California Verbal Learning Test (CVLT) Trial 1 learning score (range 0-16; higher score indicates better memory) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment2.45
Levetiracetam2.5

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Design Fluency

Change in Design Fluency score (Score range: lowest score = 0; there is no upper limit. A higher score reflects more designs generated, hence better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment2.8
Levetiracetam.83

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Digit Span

Change in Digit Span score (score ranges from 0-30; higher scores indicate better performance). Scores indicate the number of digit sequences correctly recalled, forwards and backwards. (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionnumber recalled (Mean)
No Treatment.73
Levetiracetam-.33

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Digit Symbol

Change in Digit Symbol Score (The score is the number of items completed. A higher score reflects better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment3.2
Levetiracetam1.5

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Facial Recognition Accuracy

Change in Facial Recognition Accuracy Score (accuracy ranges from 0-100%) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment.01
Levetiracetam.03

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Facial Recognition Reaction Time

Change in Facial Recognition Reaction Time Score (indicates processing speed, with reaction time measured in seconds) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment-66.76
Levetiracetam.61

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Grooved Pegboard

Change in Grooved Pegboard Score (The score is the time for completion. A lower score reflects better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment-4.73
Levetiracetam-4.36

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: LNS

Change in Letter-Number Sequencing score (LNS; score ranges from 0-21; higher scores indicate better performance). The score reflects the number of items that the subject can correctly recall and place in proper alphabetical and numerical sequence. (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment.18
Levetiracetam-0.5

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: NDDIE

Change in Neurological Disorders Depression Inventory for Epilepsy (NDDIE) score (scores range from 0-24; higher scores indicate greater depressive symptoms) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment0.18
Levetiracetam1.5

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Non-verbal Working Memory Accuracy

Change in Non-verbal Working Memory Accuracy Score (accuracy ranges from 0-100%) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment-.01
Levetiracetam0

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Non-verbal Working Memory Reaction Time

Change in Non-verbal Working Memory Reaction Time Score (indicates processing speed, with reaction time measured in seconds) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment-31.99
Levetiracetam-25.54

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: QOLIE

Change in Quality of Life Inventory in Epilepsy-89 score (QOLIE; score ranges from 0-100; higher scores reflect better quality of life) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
Levetiracetam19.6

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Spatial Span

Change in Spatial Span score (score ranges from 0-32; higher scores indicate better performance). Scores indicate the number of spatial sequences correctly recalled, forwards and backwards. (NCT00916149)
Timeframe: 1 and 11 Weeks

Interventionnumber recalled (Mean)
No Treatment.36
Levetiracetam-1.67

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Stroop

Change in Stroop score (The score is the time for completion in seconds; less time reflects better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment.98
Levetiracetam-7.3

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Trails Test

Change in Trails Test score (The score is the time for completion in seconds. A lower score reflects better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment-9.51
Levetiracetam11.29

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Verbal Fluency

Change in Verbal Fluency score (Score range: lowest score = 0, with no upper limit, reflecting total number of words generated. Higher scores indicate better performance.) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionscores on a scale (Mean)
No Treatment-1.55
Levetiracetam-.83

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Verbal Recognition Accuracy

Change in Verbal Recognition Accuracy Score (accuracy ranges from 0-100%) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment.02
Levetiracetam.14

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Verbal Recognition Reaction Time

Change in Verbal Recognition Reaction Time Score (indicates processing speed, with reaction time measured in seconds) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment2.98
Levetiracetam-6.1

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Verbal Working Memory Accuracy

Change in Verbal Working Memory Accuracy Score (range 0-100%) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionpercentage of correct responses (Mean)
No Treatment0
Levetiracetam-.02

Performance on Neuropsychological Batteries and Computerized Cognitive Testing: Verbal Working Memory Reaction Time

Change in Verbal Working Memory Reaction Time Score, with reaction time measured in seconds (indicates processing speed) (NCT00916149)
Timeframe: 1 and 11 weeks

Interventionseconds (Mean)
No Treatment-54.76
Levetiracetam-9.36

Reviews

11 reviews available for amobarbital and Epilepsy, Temporal Lobe

ArticleYear
Beyond the Wada: An updated approach to pre-surgical language and memory testing: An updated review of available evaluation techniques and recommended workflow to limit Wada test use to essential clinical cases.
    Epilepsy research, 2021, Volume: 174

    Topics: Amobarbital; Epilepsy, Temporal Lobe; Functional Laterality; Humans; Language; Magnetic Resonance Im

2021
Comparing the Intracarotid Amobarbital Test and Functional MRI for the Presurgical Evaluation of Language in Epilepsy.
    Current neurology and neuroscience reports, 2017, Volume: 17, Issue:7

    Topics: Amobarbital; Brain Mapping; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Functional Laterality

2017
The role of functional MRI in the presurgical investigation of temporal lobe epilepsy patients: a clinical perspective and review.
    Journal of clinical and experimental neuropsychology, 2002, Volume: 24, Issue:5

    Topics: Amobarbital; Epilepsy, Temporal Lobe; Humans; Hypnotics and Sedatives; Language Development; Languag

2002
Atypical language cortex in the left temporal lobe: relationship to bilateral language.
    Neurology, 2004, Nov-23, Volume: 63, Issue:10

    Topics: Adolescent; Adult; Amobarbital; Anterior Temporal Lobectomy; Brain Mapping; Brain Neoplasms; Carotid

2004
[Can functional MRI replace the Wada test?].
    Neuro-Chirurgie, 2008, Volume: 54, Issue:3

    Topics: Amobarbital; Epilepsy, Temporal Lobe; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; N

2008
Intracarotid amobarbital procedure. The Wada test.
    Neuroimaging clinics of North America, 1995, Volume: 5, Issue:4

    Topics: Amobarbital; Carotid Arteries; Epilepsy, Temporal Lobe; Forecasting; Hippocampus; Humans; Injections

1995
Neuropsychological evaluation in epilepsy surgery.
    Epilepsia, 1997, Volume: 38 Suppl 4

    Topics: Adult; Amobarbital; Brain Mapping; Epilepsy, Temporal Lobe; Functional Laterality; Humans; Magnetic

1997
Use of the intracarotid amobarbital procedure in the evaluation of memory.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 1997, Volume: 14, Issue:4

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Cerebral Decortication; Child; Domina

1997
Contributions of electroencephalography and electrocorticography to the neurosurgical treatment of the epilepsies.
    Advances in neurology, 1975, Volume: 8

    Topics: Amobarbital; Bemegride; Cerebral Cortex; Electric Stimulation; Electrodes; Electrodes, Implanted; El

1975
Mesial temporal sclerosis: pathogenesis, diagnosis, and management.
    Epilepsia, 1990, Volume: 31 Suppl 3

    Topics: Adolescent; Adult; Amobarbital; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Mag

1990
The electroencephalogram as a diagnostic aid in neurosurgery: a review.
    Clinical neurosurgery, 1969, Volume: 16

    Topics: Adult; Age Factors; Amobarbital; Brain Diseases; Brain Injuries; Brain Neoplasms; Child; Child, Pres

1969

Trials

21 trials available for amobarbital and Epilepsy, Temporal Lobe

ArticleYear
Wada memory asymmetry scores and postoperative memory outcome in left temporal epilepsy.
    Seizure, 2008, Volume: 17, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Epilepsy, Temporal Lobe; Female; Functional Lateral

2008
Stimulus type affects Wada memory performance.
    Epilepsy & behavior : E&B, 2008, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Child; Epilepsy, Temporal Lobe; Female; Functional Laterality; Human

2008
Postoperative memory prediction in left temporal lobe epilepsy: the Wada test is of no added value to preoperative neuropsychological assessment and MRI.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:2

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Epilepsy, Temporal Lobe; Female; Humans; Magnetic R

2009
Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy.
    Epilepsia, 2010, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Amobarbital; Anticonvulsants; Child; Dominance, Cerebral; Double-Blind Method; Dr

2010
Awareness of deficits during intracarotid anesthetic procedures in epilepsy: Comparisons of motor, naming, and comprehension awareness under amobarbital versus under etomidate.
    Epilepsy & behavior : E&B, 2010, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Awareness; Comprehension; Electroencephalography; Epilepsy, Temporal

2010
FMRI-determined language lateralization in patients with unilateral or mixed language dominance according to the Wada test.
    NeuroImage, 2002, Volume: 17, Issue:1

    Topics: Adult; Amobarbital; Cerebral Cortex; Child; Dominance, Cerebral; Electroencephalography; Epilepsy, T

2002
Language lateralization in patients with temporal lobe epilepsy: a comparison of functional transcranial Doppler sonography and the Wada test.
    NeuroImage, 2003, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Algorithms; Amobarbital; Carotid Arteries; Child; Epilepsy, Temporal Lobe; Female

2003
Left hemisphere dysfunction affects dichotic listening in patients with temporal lobe epilepsy.
    The International journal of neuroscience, 2003, Volume: 113, Issue:9

    Topics: Acoustic Stimulation; Adolescent; Adult; Amobarbital; Auditory Perception; Brain Mapping; Dichotic L

2003
Pre- and postoperative intracarotid amytal procedure: an assessment of validity.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:5

    Topics: Adult; Amobarbital; Amygdala; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Functional Laterali

2003
The selective amobarbital test in the anterior choroidal artery: perfusion pattern assessed by intraarterial SPECT and prediction of postoperative verbal memory.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Electroenceph

2008
Predictors of outcome after anterior temporal lobectomy: the intracarotid amobarbital test.
    Neurology, 1994, Volume: 44, Issue:12

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Carotid Artery, Internal; Child; Electroencephalog

1994
Results from the intracarotid amytal procedure in patients with uni or bitemporal lobe epilepsy and mesial sclerosis.
    Arquivos de neuro-psiquiatria, 1995, Volume: 53, Issue:3-B

    Topics: Amobarbital; Animals; Carotid Artery, Internal; Electroencephalography; Epilepsy, Temporal Lobe; Fun

1995
Memory performance on the intracarotid amobarbital procedure as a predicator of seizure focus.
    Epilepsy research, 1996, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe

1996
Evidence of very fast memory consolidation: an intracarotid amytal study.
    Neuroreport, 1997, Sep-08, Volume: 8, Issue:13

    Topics: Amobarbital; Carotid Artery, Internal; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans;

1997
The effect of early versus late onset of temporal lobe epilepsy on hemispheric memory laterality: an intracarotid amobarbital procedure study.
    Journal of Korean medical science, 1997, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Age Factors; Age of Onset; Amobarbital; Brain; Carotid Artery, Internal; Child; E

1997
Differential lateralization of memory discrimination and response bias in temporal lobe epilepsy patients.
    Journal of the International Neuropsychological Society : JINS, 1998, Volume: 4, Issue:5

    Topics: Adult; Amobarbital; Carotid Arteries; Cognition; Discrimination, Psychological; Epilepsy, Temporal L

1998
Predictive value of the intracarotid amobarbital test in bihemispheric seizure onset.
    Neurology, 1999, Jan-15, Volume: 52, Issue:2

    Topics: Adult; Amobarbital; Carotid Arteries; Diagnosis, Differential; Electroencephalography; Epilepsies, P

1999
Presurgical evaluation and surgical outcome of temporal lobe epilepsy.
    Pediatric neurology, 1999, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amobarbital; Brain Diseases; Brain Neoplasms; Child; Electroencephal

1999
Hemispheric asymmetries in arousal affect outcome of the intracarotid amobarbital test.
    Neurology, 1999, May-12, Volume: 52, Issue:8

    Topics: Adult; Amobarbital; Arousal; Brain; Carotid Arteries; Electroencephalography; Epilepsy, Temporal Lob

1999
The wada test: prediction of focus lateralization by asymmetric and symmetric recall.
    Epilepsy research, 2000, Volume: 39, Issue:3

    Topics: Adult; Amobarbital; Cerebral Angiography; Electroencephalography; Epilepsy, Temporal Lobe; Female; F

2000
Heart rate does not decrease after right hemispheric amobarbital injection.
    Neurology, 2000, Jun-27, Volume: 54, Issue:12

    Topics: Amobarbital; Artifacts; Carotid Arteries; Electrocardiography; Electroencephalography; Epilepsy, Tem

2000

Other Studies

157 other studies available for amobarbital and Epilepsy, Temporal Lobe

ArticleYear
Electrical Wada for pre-surgical memory testing: a case report.
    Epileptic disorders : international epilepsy journal with videotape, 2022, Apr-01, Volume: 24, Issue:2

    Topics: Amobarbital; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Memory; Memory Disorder

2022
Advantages of methohexital over amobarbital in determining hemispheric language and memory lateralization in the Wada test - A retrospective study.
    Epilepsy & behavior : E&B, 2020, Volume: 113

    Topics: Adolescent; Adult; Amobarbital; Anesthetics; Cerebrum; Child; Epilepsy, Temporal Lobe; Female; Funct

2020
Drug load and memory during intracarotid amobarbital procedure in epilepsy.
    Acta neurologica Scandinavica, 2021, Volume: 144, Issue:5

    Topics: Adult; Amobarbital; Epilepsy; Epilepsy, Temporal Lobe; Functional Laterality; Humans; Injections, In

2021
Naming outcome after left or right temporal lobectomy in patients with bilateral language representation by Wada testing.
    Epilepsy & behavior : E&B, 2013, Volume: 28, Issue:1

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Epilepsy, Temporal Lobe; Female; Functional Lateral

2013
Sensitivity and specificity of Ankara University Cerebral Dominance Inventory in comparison with the Wada test.
    Acta neurologica Belgica, 2014, Volume: 114, Issue:1

    Topics: Academic Medical Centers; Adolescent; Adult; Amobarbital; Dominance, Cerebral; Epilepsy, Temporal Lo

2014
Bilateral Wada test: amobarbital or propofol?
    Seizure, 2014, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anesthetics; Brain; Consciousness; Epilepsy, Temporal Lobe; Female;

2014
Cortical cartography reveals political and physical maps.
    Epilepsia, 2014, Volume: 55, Issue:5

    Topics: Amobarbital; Brain Mapping; Cerebral Cortex; Craniotomy; Epilepsy, Temporal Lobe; Humans; Magnetic R

2014
Is it time to replace the Wada test and put awake craniotomy to sleep?
    Epilepsia, 2014, Volume: 55, Issue:5

    Topics: Amobarbital; Brain Mapping; Carotid Arteries; Cerebral Cortex; Craniotomy; Epilepsy, Temporal Lobe;

2014
Grammar tests increase the ability to lateralize language function in the Wada test.
    Epilepsy research, 2014, Volume: 108, Issue:10

    Topics: Adult; Amobarbital; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Later

2014
The intracarotid amobarbital or Wada test: unilateral or bilateral?
    Acta neurologica Scandinavica, 2009, Volume: 119, Issue:3

    Topics: Adolescent; Amnesia; Amobarbital; Aphasia; Carotid Artery, Internal; Child; Child, Preschool; Domina

2009
Threshold-independent functional MRI determination of language dominance: a validation study against clinical gold standards.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:2

    Topics: Adult; Aged; Amobarbital; Analysis of Variance; Brain; Brain Mapping; Epilepsy, Temporal Lobe; Femal

2009
Extent of initial injury determines language lateralization in mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS).
    Epilepsia, 2009, Volume: 50, Issue:10

    Topics: Adult; Amobarbital; Brain Injuries; Brain Mapping; Electroencephalography; Epilepsy, Temporal Lobe;

2009
Incidence and clinical decision making for the Wada test over one decade: 1997-2007.
    Epileptic disorders : international epilepsy journal with videotape, 2010, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Amobarbital; Child; Child, Preschool; Electrodes, Implanted; Epilepsy, Temp

2010
False lateralization of seizure onset by scalp EEG in neocortical temporal lobe epilepsy.
    Seizure, 2011, Volume: 20, Issue:6

    Topics: Amobarbital; Electroencephalography; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Fun

2011
[Changes in verbal and nonverbal memory associated with bilateral hippocampal electrode implantation for epilepsy surgery].
    Revista de neurologia, 2012, Nov-01, Volume: 55, Issue:9

    Topics: Adult; Aged; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Dominance, Cerebral

2012
Memory lateralization in medial temporal lobe epilepsy assessed by functional MRI.
    Epilepsia, 2002, Volume: 43, Issue:8

    Topics: Adult; Amobarbital; Behavior; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female

2002
Spanish language mapping using MEG: a validation study.
    NeuroImage, 2002, Volume: 17, Issue:3

    Topics: Adult; Amobarbital; Aphasia; Brain Mapping; Dominance, Cerebral; Electrodes, Implanted; Epilepsy, Te

2002
A direct test for lateralization of language activation using fMRI: comparison with invasive assessments in children with epilepsy.
    NeuroImage, 2002, Volume: 17, Issue:4

    Topics: Adolescent; Amobarbital; Brain Damage, Chronic; Cerebral Cortex; Child; Dominance, Cerebral; Electro

2002
Ictal urinary urge: further evidence for lateralization to the nondominant hemisphere.
    Epilepsia, 2003, Volume: 44, Issue:1

    Topics: Adult; Amobarbital; Awareness; Child; Dominance, Cerebral; Electroencephalography; Epilepsies, Parti

2003
Functional MR imaging in assessment of language dominance in epileptic patients.
    NeuroImage, 2003, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anomia; Brain Mapping; Child; Dominance, Cerebral; Electroencephalog

2003
Lateralising value of neuropsychological protocols for presurgical assessment of temporal lobe epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:3

    Topics: Adult; Amobarbital; Brain Mapping; Cognition Disorders; Electrodes, Implanted; Electroencephalograph

2003
Predicting verbal memory decline following anterior temporal lobectomy (ATL).
    Neurology, 2003, Apr-22, Volume: 60, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Dominance, Cerebral; Epil

2003
Predicting verbal memory decline following anterior temporal lobectomy (ATL).
    Neurology, 2003, Apr-22, Volume: 60, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Dominance, Cerebral; Epil

2003
Predicting verbal memory decline following anterior temporal lobectomy (ATL).
    Neurology, 2003, Apr-22, Volume: 60, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Dominance, Cerebral; Epil

2003
Predicting verbal memory decline following anterior temporal lobectomy (ATL).
    Neurology, 2003, Apr-22, Volume: 60, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Dominance, Cerebral; Epil

2003
Wada memory performance predicts seizure outcome after epilepsy surgery in children.
    Epilepsia, 2003, Volume: 44, Issue:7

    Topics: Adolescent; Amobarbital; Anterior Temporal Lobectomy; Cerebral Cortex; Child; Child, Preschool; Domi

2003
Identifying potential surgical candidates in patients with evidence of bitemporal epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Anterior Temporal Lobectomy; Dominance, Cerebral; Electroencephalogr

2003
EPISODIC DEPERSONALIZATION; OBSERVATIONS ON 7 PATIENTS.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Alcoholic Beverages; Amitriptyline; Amobarbital; Cochlea; Convulsive Therapy; Depersonalization; Dep

1964
SOME SCALP AND DEPTH ELECTROGRAPHIC OBSERVATIONS ON THE ACTION OF INTRACAROTID SODIUM AMYTAL INJECTION ON EPILEPTIC DISCHARGES IN MAN.
    Electroencephalography and clinical neurophysiology, 1963, Volume: 15

    Topics: Amobarbital; Carotid Arteries; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans; Ma

1963
Neuropsychological effects associated with temporal lobectomy and amygdalohippocampectomy depending on Wada test failure.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Amygdala; Brain Damage, Chronic; Dominance, Cerebral; Epilepsy, Temp

2004
Effects of topiramate on memory performance on the intracarotid amobarbital (Wada) test.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anterior Temporal Lobectomy; Anticonvulsants; Dominance, Cerebral; D

2004
High-resolution functional MRI at 3T in healthy and epilepsy subjects: hippocampal activation with picture encoding task.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Brain Mapping; Dominance, Cerebral; Epilepsy; Epile

2004
Structural versus functional prediction of memory change following anterior temporal lobectomy.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Dominance, Cerebral; Epilepsy, Temporal Lobe; Follo

2004
MRI language dominance assessment in epilepsy patients at 1.0 T: region of interest analysis and comparison with intracarotid amytal testing.
    Neuroradiology, 2004, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Carotid Artery, Internal; Child; Dominance, Cerebral;

2004
Can the Wada test evaluate mesial temporal function? A SPECT study.
    Neurology, 2004, Jun-22, Volume: 62, Issue:12

    Topics: Adolescent; Adult; Amnesia; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal; Cere

2004
Selective posterior cerebral artery amobarbital test: its role in presurgical memory assessment in temporal lobe epilepsy.
    Epilepsia, 2004, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Amobarbital; Brain; Brain Mapping; Cognition Disorders; Epilepsy, Temporal Lobe;

2004
Bizarre behavior during intracarotid sodium amytal testing (Wada test): are they predictable?
    Arquivos de neuro-psiquiatria, 2004, Volume: 62, Issue:2B

    Topics: Adolescent; Adult; Amobarbital; Behavior; Brain Neoplasms; Carotid Arteries; Epilepsy; Epilepsy, Tem

2004
Contribution of neuropsychology to epilepsy surgery.
    The Israel journal of psychiatry and related sciences, 2004, Volume: 41, Issue:2

    Topics: Adult; Amobarbital; Brain; Cognition Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Fun

2004
Probabilistic map of blood flow distribution in the brain from the internal carotid artery.
    NeuroImage, 2004, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Algorithms; Amobarbital; Anterior Temporal Lobectomy; Brain; Carotid Artery, Inte

2004
Organization of receptive language-specific cortex before and after left temporal lobectomy.
    Neurology, 2005, Feb-08, Volume: 64, Issue:3

    Topics: Amobarbital; Anterior Temporal Lobectomy; Brain Mapping; Carotid Arteries; Dominance, Cerebral; Epil

2005
Transient global amnesia triggered by the intracarotid amobarbital procedure.
    Epilepsy & behavior : E&B, 2005, Volume: 6, Issue:2

    Topics: Adult; Amnesia, Transient Global; Amobarbital; Brain Neoplasms; Epilepsy, Temporal Lobe; Female; Fun

2005
Epilepsy surgery in professional musicians: subjective and objective reports of three cases.
    Epilepsy & behavior : E&B, 2005, Volume: 7, Issue:3

    Topics: Adult; Amobarbital; Epilepsy, Temporal Lobe; Humans; Hypnotics and Sedatives; Intelligence Tests; Ma

2005
Limitations of Wada memory asymmetry as a predictor of outcomes after temporal lobectomy.
    Neurology, 2005, Sep-13, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amobarbital; Brain; Epilepsy, Temporal Lobe; Functional

2005
Relationship between bilateral temporal hypometabolism and EEG findings for mesial temporal lobe epilepsy: analysis of 18F-FDG PET using SPM.
    Seizure, 2006, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Amobarbital; Anterior Temporal Lobectomy; Child; Electroencephalography; Epilepsy

2006
Memory performance during the intracarotid amobarbital procedure and neuropsychological assessment in medial temporal lobe epilepsy: the limits of material specificity.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:2

    Topics: Adult; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans;

2006
Clinical relevance of memory performance during Wada is stimulus type dependent.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:2

    Topics: Adult; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans;

2006
Selective posterior cerebral artery amobarbital test in patients with temporal lobe epilepsy for surgical treatment.
    Seizure, 2006, Volume: 15, Issue:2

    Topics: Adult; Amobarbital; Epilepsy, Temporal Lobe; Female; Humans; Hypnotics and Sedatives; Male; Memory;

2006
Hypersalivation in temporal lobe epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:3

    Topics: Adult; Age of Onset; Amobarbital; Amygdala; Anterior Temporal Lobectomy; Carotid Artery, Internal; C

2006
FMRI lateralization of expressive language in children with cerebral lesions.
    Epilepsia, 2006, Volume: 47, Issue:6

    Topics: Adolescent; Amobarbital; Brain Mapping; Cerebral Cortex; Child; Epilepsy; Epilepsy, Frontal Lobe; Ep

2006
Language lateralization in temporal lobe epilepsy: a comparison between fMRI and the Wada Test.
    Epilepsia, 2006, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Aphasia; Brain Mapping; Carotid Artery, Internal; Cerebral Cortex; E

2006
Effects of illness duration on memory processing of patients with temporal lobe epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Aphasia; Brain Mapping; Cerebral Cortex; Epilepsy, Temporal Lobe; Fe

2006
Speech preservation during language-dominant, left temporal lobe seizures: report of a rare, potentially misleading finding.
    Epilepsia, 2006, Volume: 47, Issue:8

    Topics: Adult; Age of Onset; Amobarbital; Aphasia; Brain Mapping; Cerebral Cortex; Child; Electrodes, Implan

2006
Speech recognition impairments in patients with intractable right temporal lobe epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Aphasia; Brain Mapping; Cerebral Cortex; Epilepsy; Epilepsy, Frontal

2006
Hippocampal memory function as reflected by the intracarotid sodium methohexital Wada test.
    Epilepsy & behavior : E&B, 2006, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Anesthetics, Intravenous; Epilepsy, Temporal Lobe; Female; Functiona

2006
Deficient memory acquisition in temporal lobe epilepsy is predicted by hippocampal granule cell loss.
    Neurology, 2006, Oct-24, Volume: 67, Issue:8

    Topics: Adult; Amobarbital; Carotid Arteries; Cell Count; Dentate Gyrus; Epilepsy, Temporal Lobe; Female; Hi

2006
fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.
    Experimental brain research, 2007, Volume: 179, Issue:3

    Topics: Adult; Amobarbital; Brain Mapping; Cerebral Cortex; Epilepsy, Temporal Lobe; Female; Frontal Lobe; F

2007
The role of the intracarotid amobarbital procedure in predicting verbal memory decline after temporal lobe resection.
    Epilepsia, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amobarbital; Anterior Temporal Lobectomy; Carotid Artery, Internal;

2007
Multivariate neuropsychological prediction of seizure lateralization in temporal epilepsy surgical cases.
    Epilepsia, 2007, Volume: 48, Issue:8

    Topics: Aged; Amobarbital; Brain; Brain Mapping; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hum

2007
Intracarotid amobarbital procedure in post-temporal lobectomy patients.
    Epilepsia, 2007, Volume: 48, Issue:8

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Brain Mapping; Carotid Artery, Internal; Cerebral C

2007
Interictal and postictal language testing accurately lateralizes language dominant temporal lobe complex partial seizures.
    Epilepsia, 2008, Volume: 49, Issue:1

    Topics: Amobarbital; Anterior Temporal Lobectomy; Electroencephalography; Epilepsy, Complex Partial; Epileps

2008
Can pentobarbital replace amobarbital in the Wada test?
    Epilepsy & behavior : E&B, 2007, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Child; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans;

2007
Repeated intracarotid amobarbital tests.
    Epilepsia, 2007, Volume: 48, Issue:9

    Topics: Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Epilepsy, Temporal Lobe; Functional Laterali

2007
Strategies for surgical treatment of epilepsies in developing countries.
    Epilepsia, 2008, Volume: 49, Issue:3

    Topics: Amobarbital; Anterior Temporal Lobectomy; Brain Mapping; Developing Countries; Electroencephalograph

2008
[Carotid artery infusion of propofol for the Wada test].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:9

    Topics: Adult; Amobarbital; Anticonvulsants; Carotid Artery, Internal; Diagnostic Techniques, Neurological;

2007
The role of the Wada test in the surgical treatment of temporal lobe epilepsy: an international survey.
    Epilepsia, 2008, Volume: 49, Issue:4

    Topics: Amnesia; Amobarbital; Attitude of Health Personnel; Carotid Artery, Internal; Cerebral Cortex; Data

2008
Temporal lobe neoplasm and seizures: how deep does the story go?
    Epileptic disorders : international epilepsy journal with videotape, 2008, Volume: 10, Issue:1

    Topics: Adult; Amobarbital; Brain; Brain Neoplasms; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Hu

2008
Intracarotid amytal test in the assessment of language dominance.
    Advances in neurology, 1984, Volume: 42

    Topics: Adolescent; Adult; Amobarbital; Anomia; Aphasia; Carotid Artery, Internal; Child; Dominance, Cerebra

1984
Observations on verbal, pictorial and stereognostic memory in epileptic patients during intracarotid Amytal testing.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 99

    Topics: Adolescent; Adult; Amobarbital; Carotid Artery, Internal; Epilepsy; Epilepsy, Temporal Lobe; Female;

1984
Resumption of behavior following intracarotid sodium amobarbital injection.
    Annals of neurology, 1984, Volume: 15, Issue:1

    Topics: Amobarbital; Behavior; Carotid Arteries; Electroencephalography; Epilepsy, Temporal Lobe; Humans; In

1984
Dichotic monitoring as a test of hemispheric dominance in cases of epilepsy.
    Cortex; a journal devoted to the study of the nervous system and behavior, 1981, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amobarbital; Dominance, Cerebral; Epilepsies, Partial; Epilepsy; Epilepsy, Tempor

1981
Correlation of criteria used for localizing epileptic foci in patients considered for surgical therapy of epilepsy.
    Annals of neurology, 1981, Volume: 9, Issue:3

    Topics: Adult; Amobarbital; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Me

1981
The value of PET scan (and MRI and Wada test) in patients with bitemporal epileptiform abnormalities.
    Archives of neurology, 1995, Volume: 52, Issue:11

    Topics: Adult; Amobarbital; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Later

1995
Do intracarotid barbiturate injections offer a way to investigate hemispheric models of anosognosia?
    Journal of clinical and experimental neuropsychology, 1995, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Agnosia; Amobarbital; Attention; Awareness; Dominance, Cerebral; Epilepsy, Tempor

1995
Intraoperative hippocampal cooling and Wada memory testing in the evaluation of amnesia risk following anterior temporal lobectomy.
    Archives of neurology, 1995, Volume: 52, Issue:9

    Topics: Adult; Amnesia; Amobarbital; Cryotherapy; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Intr

1995
Quantitative and qualitative evaluation of patterns of cerebral language dominance. An amobarbital study.
    Brain and language, 1994, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Carotid Artery, Internal; Cerebral Cortex; Child; Dom

1994
Lateralizing value of transient hypofrontality during Wada's test.
    Seizure, 1993, Volume: 2, Issue:2

    Topics: Amobarbital; Brain Mapping; Dominance, Cerebral; Electroencephalography; Epilepsy, Temporal Lobe; Fr

1993
The association of multiple personality and temporolimbic epilepsy. Intracarotid amobarbital test observations.
    Archives of neurology, 1993, Volume: 50, Issue:10

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Delusions; Dissociative Identity Disorder; Epileps

1993
Hemisphere inactivation and mood-state changes.
    Brain and cognition, 1993, Volume: 23, Issue:2

    Topics: Adult; Affect; Amobarbital; Brain; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Female; Fun

1993
Intracarotid amobarbital injection produces hippocampal EEG changes in patients with temporal lobe epilepsy.
    Epilepsy research, 1993, Volume: 15, Issue:1

    Topics: Adult; Amobarbital; Carotid Arteries; Electroencephalography; Epilepsy, Temporal Lobe; Female; Funct

1993
Material-specific memory in the intracarotid amobarbital procedure.
    Neurology, 1993, Volume: 43, Issue:4

    Topics: Amobarbital; Discriminant Analysis; Dominance, Cerebral; Epilepsies, Partial; Epilepsy, Temporal Lob

1993
Unilateral hemispheric memory and hippocampal neuronal density in temporal lobe epilepsy.
    Neurosurgery, 1993, Volume: 32, Issue:4

    Topics: Adult; Amobarbital; Carotid Arteries; Cell Count; Epilepsy, Temporal Lobe; Female; Functional Latera

1993
Functional MRI measurement of language lateralization in Wada-tested patients.
    Brain : a journal of neurology, 1995, Volume: 118 ( Pt 6)

    Topics: Adult; Amobarbital; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hum

1995
Ictal speech manifestations in temporal lobe epilepsy: a video-EEG study.
    Epilepsia, 1996, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Amobarbital; Electroencephalography; Epilepsy, Complex Partial; Epilepsy, Tempora

1996
Localization of temporal lobe foci by ictal EEG patterns.
    Epilepsia, 1996, Volume: 37, Issue:4

    Topics: Amobarbital; Carotid Artery, Internal; Diagnosis, Differential; Electrodes, Implanted; Electroenceph

1996
Postictal language dysfunction in patients with right or bilateral hemispheric language localization.
    Epilepsia, 1996, Volume: 37, Issue:10

    Topics: Adult; Aged; Amobarbital; Electroencephalography; Epilepsy, Temporal Lobe; Follow-Up Studies; Functi

1996
A proposed modification of the Wada test for presurgical assessment in temporal lobe epilepsy.
    Neuroradiology, 1996, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Amobarbital; Cerebral Angiography; Cerebral Arteries; Epilepsy, Temporal Lobe; Fe

1996
Superselective intra-arterial amytal (Wada test) in temporal lobe epilepsy: basics for neuroradiological investigations.
    Neuroradiology, 1996, Volume: 38, Issue:5

    Topics: Amobarbital; Cerebral Angiography; Cerebral Arteries; Epilepsy, Temporal Lobe; Humans; Injections, I

1996
Intracartotid amobarbital procedure memory performance and age at first risk for seizures distinguish between lateral neocortical and mesial temporal lobe epilepsy.
    Epilepsia, 1996, Volume: 37, Issue:11

    Topics: Adult; Age of Onset; Amobarbital; Carotid Artery, Internal; Diagnosis, Differential; Epilepsy, Tempo

1996
Episodic memory dysfunction during sodium amytal testing of epileptic patients in relation to posterior cerebral artery perfusion.
    Journal of clinical and experimental neuropsychology, 1996, Volume: 18, Issue:1

    Topics: Adult; Amobarbital; Cerebral Arteries; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Female;

1996
Effect of Wada memory stimulus type in discriminating lateralized temporal lobe impairment.
    Epilepsia, 1997, Volume: 38, Issue:2

    Topics: Amobarbital; Diagnosis, Differential; Epilepsy, Temporal Lobe; Form Perception; Functional Lateralit

1997
Serial recovery of language during the intracarotid amobarbital procedure.
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Adult; Amobarbital; Chi-Square Distribution; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; H

1997
Effects of hemisphere speech dominance and seizure focus on patterns of behavioral response errors for three types of stimuli.
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Adult; Amobarbital; Analysis of Variance; Cross-Sectional Studies; Dominance, Cerebral; Epilepsy, Te

1997
Level of consciousness and memory during the intracarotid sodium amobarbital procedure.
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Analysis of Variance; Consciousness; Cross-Sectional Studies; Domina

1997
Sodium amobarbital memory tests: what do they predict?
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Amnesia; Amobarbital; Analysis of Variance; Cerebral Decortication; Communication Disorders; Dominan

1997
An exploratory comparison of three methods of memory assessment with the intracarotid amobarbital procedure.
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Adult; Amobarbital; Cerebral Decortication; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Fo

1997
Effect of focus lateralization on memory assessment during the intracarotid amobarbital procedure.
    Brain and cognition, 1997, Volume: 33, Issue:2

    Topics: Amobarbital; Analysis of Variance; Cross-Sectional Studies; Dominance, Cerebral; Epilepsy, Temporal

1997
Individual patient prediction of seizure lateralization in temporal lobe epilepsy: a comparison between neuropsychological memory measures and the Intracarotid Amobarbital Procedure.
    Journal of the International Neuropsychological Society : JINS, 1997, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fema

1997
Cerebral hemispheric lateralization in cardiac autonomic control.
    Archives of neurology, 1997, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Amobarbital; Analysis of Variance; Brain; Electrocardiography, Ambulatory; Epilep

1997
Right hemisphere mediation of verbal learning and memory in acquired right hemisphere speech dominant patients.
    Journal of the International Neuropsychological Society : JINS, 1995, Volume: 1, Issue:6

    Topics: Adult; Amobarbital; Brain Mapping; Cerebral Cortex; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fe

1995
Cerebral metabolic changes (18F-FDG PET) during selective anterior temporal lobe amobarbital test.
    European neurology, 1997, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Central Nervous System Depressants; Epilepsy, Temporal Lobe; Female;

1997
Sensitivity and specificity of asymmetric recall on WADA test to predict outcome after temporal lobectomy.
    Neurology, 1998, Volume: 50, Issue:2

    Topics: Adult; Age of Onset; Amobarbital; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; Humans; Langua

1998
FDG-PET and MRI in temporal lobe epilepsy: relationship to febrile seizures, hippocampal sclerosis and outcome.
    Acta neurologica Scandinavica, 1998, Volume: 97, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Atrophy; Carotid Artery, Internal; Child; Electroencephalography; Ep

1998
Interhemispheric memory transfer in the intracarotid amobarbital procedure.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 1998, Volume: 11, Issue:1

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Dominance, Cerebral; Epilepsy, Tempor

1998
Selective amobarbital test for the determination of language function in patients with epilepsy with frontal and posterior temporal brain lesions.
    Epilepsia, 1998, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Cerebral Angiography; Epilepsy; Epilepsy, Frontal Lobe; Epilepsy, Te

1998
Asymmetries in the effect of side of seizure onset on recognition memory following intracarotid amobarbital injection.
    Epilepsia, 1997, Volume: 38, Issue:11

    Topics: Adolescent; Adult; Age of Onset; Amobarbital; Brain; Carotid Arteries; Epilepsy, Temporal Lobe; Fema

1997
The relation between quantitative MRI measures of hippocampal structure and the intracarotid amobarbital test.
    Epilepsia, 1997, Volume: 38, Issue:9

    Topics: Adult; Amobarbital; Brain; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Functional Laterality;

1997
Language-related hemispheric asymmetry in healthy subjects and patients with temporal lobe epilepsy as studied by event-related brain potentials and intracarotid amobarbital test.
    Electroencephalography and clinical neurophysiology, 1998, Volume: 108, Issue:3

    Topics: Adult; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Evoked Potential

1998
Ipsilateral neglect during intracarotid amobarbital test.
    Neurology, 1998, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Amobarbital; Attention; Carotid Arteries; Cerebral Cortex; Dominance, Cerebral; E

1998
Prediction of presence of hippocampal sclerosis from intracarotid amobarbital procedure memory asymmetry scores and epilepsy on set age.
    Epilepsy research, 1999, Volume: 33, Issue:2-3

    Topics: Adult; Age of Onset; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fe

1999
Evaluation of functional changes in the medial temporal region during intracarotid amobarbital procedure by use of SPECT.
    Epilepsia, 1999, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fema

1999
Criterion-based validity of an intracarotid amobarbital recognition-memory protocol.
    Epilepsia, 1999, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Amnesia; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal L

1999
Regional cerebral perfusion and amytal distribution during the Wada test.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:5

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Cerebrovascular Circulation; Epilepsy, Temporal Lobe;

1999
Amobarbital effects on the posterior hippocampus during the intracarotid amobarbital test.
    Neurology, 1999, May-12, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Child; Electroencephalography; Epilepsy, Temporal

1999
Time perception following unilateral amobarbital injection in patients with temporal lobe epilepsy.
    Journal of clinical and experimental neuropsychology, 1999, Volume: 21, Issue:3

    Topics: Adult; Amobarbital; Attention; Case-Control Studies; Dominance, Cerebral; Epilepsy, Temporal Lobe; F

1999
Effects of incorporating memory confidence ratings and language handicap modifications on intracarotid amobarbital procedure (Wada test) memory asymmetry scores.
    Epilepsia, 1999, Volume: 40, Issue:9

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Functional Laterality; Humans

1999
Periictal speech as function of the age of cerebral damage.
    Advances in neurology, 1999, Volume: 81

    Topics: Adult; Age of Onset; Amobarbital; Aphasia; Brain; Dominance, Cerebral; Electroencephalography; Epile

1999
Aging limits plasticity of episodic memory functions in response to left temporal lobe damage in patients with epilepsy.
    Advances in neurology, 1999, Volume: 81

    Topics: Adult; Aging; Amobarbital; Dominance, Cerebral; Electroencephalography; Epilepsy, Temporal Lobe; Fem

1999
Functional MRI and the Wada test provide complementary information for predicting post-operative seizure control.
    Seizure, 1999, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Cognition Disorders; Drug Administration Routes; Epilepsy, Temporal

1999
Comparison of localizing values of various diagnostic tests in non-lesional medial temporal lobe epilepsy.
    Seizure, 1999, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Algorithms; Amobarbital; Amygdala; Child; Cognition Disorders; Electroencephalogr

1999
Lateralized memory deficits on the Wada test correlate with the side of lobectomy only for patients with unilateral medial temporal lobe epilepsy.
    Seizure, 1999, Volume: 8, Issue:8

    Topics: Adult; Amobarbital; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality;

1999
[Determination of language dominance using EEG spectral analysis versus the Wada test in temporal epilepsy (right-handed subjects)].
    Neurophysiologie clinique = Clinical neurophysiology, 1999, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Alpha Rhythm; Amobarbital; Cerebral Cortex; Cognition; Epilepsy, Temporal Lobe; F

1999
Contralateral EEG slowing and amobarbital distribution in Wada test: an intracarotid SPECT study.
    Epilepsia, 2000, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Brain; Carotid Artery, Internal; Child; Cysteine; Electroencephalogr

2000
The role of the intracarotid amobarbital procedure in evaluation of patients for epilepsy surgery.
    Epilepsia, 2000, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Brain; Carotid Artery, Internal; Child; Electroencephalography; Epil

2000
Risk factors for unsuccessful testing during the intracarotid amobarbital procedure in preadolescent children.
    Epilepsia, 2000, Volume: 41, Issue:5

    Topics: Age Factors; Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Child; Child, Preschool; Epilep

2000
Significance of interictal bilateral temporal hypometabolism in temporal lobe epilepsy.
    Neurology, 2000, May-09, Volume: 54, Issue:9

    Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Child; Dominance, Cerebral; Electroencephalography; E

2000
[Presurgical neuropsychological assessment in epilepsy: the Wada test].
    Harefuah, 2000, Mar-15, Volume: 138, Issue:6

    Topics: Adolescent; Adult; Amobarbital; Child; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans;

2000
Abnormal Wada and neuropsychological testing results due to topiramate therapy.
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Amobarbital; Anticonvulsants; Carbamazepine; Carotid Artery, Internal; Drug Therapy, Combination; Ep

2000
Presurgical lateralization of seizure focus and language dominant hemisphere with O-15 water PET imaging.
    Acta neurologica Scandinavica, 2000, Volume: 102, Issue:2

    Topics: Adult; Amobarbital; Dominance, Cerebral; Electroencephalography; Epilepsy, Complex Partial; Epilepsy

2000
Wada testing in pediatric patients by use of propofol anesthesia.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:7

    Topics: Adolescent; Amobarbital; Anesthesia, Intravenous; Child; Dominance, Cerebral; Epilepsy, Temporal Lob

2000
Intracarotid amobarbital procedure and prediction of postoperative memory in patients with left temporal lobe epilepsy and hippocampal sclerosis.
    Epilepsia, 2000, Volume: 41, Issue:8

    Topics: Adult; Amobarbital; Brain Diseases; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Female; Hippo

2000
Does the intracarotid amobarbital procedure predict global amnesia after temporal lobectomy?
    Epilepsia, 2000, Volume: 41, Issue:10

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Comorbidity; Epilepsy, Temporal Lobe; Follow-Up Studie

2000
SATSCOM--Selective amobarbital test intraarterial SPECT coregistered to MRI: description of a method assessing selective perfusion.
    NeuroImage, 2000, Volume: 12, Issue:6

    Topics: Adult; Amobarbital; Brain Mapping; Cerebral Cortex; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fe

2000
Correlation of temporal lobe glucose metabolism with the Wada memory test.
    Epilepsia, 2000, Volume: 41, Issue:12

    Topics: Adolescent; Adult; Amobarbital; Child; Epilepsy, Temporal Lobe; Female; Fluorodeoxyglucose F18; Func

2000
Focal functional deficits in temporal lobe epilepsy on PET scans and the intracarotid amobarbital procedure: comparison of patients with unitemporal epilepsy with those requiring intracranial recordings.
    Epilepsia, 2001, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Brain; Carotid Artery, Internal; Electrodes, Implanted; Electroencep

2001
Posterior cerebral artery Wada test: sodium amytal distribution and functional deficits.
    Neuroradiology, 2001, Volume: 43, Issue:4

    Topics: Adult; Amobarbital; Aphasia; Brain; Epilepsy, Temporal Lobe; Female; Hemianopsia; Humans; Injections

2001
Material-specific memory changes after anterior temporal lobectomy as predicted by the intracarotid amobarbital test.
    Epilepsia, 2001, Volume: 42, Issue:7

    Topics: Adult; Amobarbital; Carotid Artery, Internal; Epilepsies, Partial; Epilepsy, Temporal Lobe; Function

2001
Memory outcome after left anterior temporal lobectomy in patients with expected and reversed Wada memory asymmetry scores.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Adult; Amobarbital; Epilepsy, Temporal Lobe; Functional Laterality; Humans; Memory; Memory Disorders

2001
Crossed aphasia in a patient with complex partial seizures: evidence from intracarotid amobarbital testing, functional cortical mapping, and neuropsychological assessment.
    Journal of clinical and experimental neuropsychology, 1990, Volume: 12, Issue:2

    Topics: Adult; Amobarbital; Amygdala; Aphasia; Arousal; Brain Mapping; Cerebral Cortex; Dominance, Cerebral;

1990
Activation of the epileptic focus during intracarotid amobarbital test. Electrocorticographic registration via subdural electrodes.
    Electroencephalography and clinical neurophysiology, 1990, Volume: 75, Issue:6

    Topics: Action Potentials; Adolescent; Adult; Amobarbital; Electrodes, Implanted; Electroencephalography; Ep

1990
Severe negative emotional reactions in intracarotid sodium amytal procedures: further evidence for hemispheric asymmetries?
    Cortex; a journal devoted to the study of the nervous system and behavior, 1991, Volume: 27, Issue:2

    Topics: Adult; Amobarbital; Arousal; Carotid Arteries; Depression; Dominance, Cerebral; Electroencephalograp

1991
Mapping distribution of amobarbital sodium in the intracarotid Wada test with use of Tc-99m HMPAO with SPECT.
    Radiology, 1991, Volume: 181, Issue:2

    Topics: Amobarbital; Brain; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Humans; Organotechnetium C

1991
Mapping the distribution of amobarbital sodium in the intracarotid Wada test by use of Tc-99m HMPAO with SPECT.
    Radiology, 1991, Volume: 178, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Angiography, Digital Subtraction; Carotid Artery, Internal; Dominanc

1991
Hemisphere memory differences in Sodium Amytal testing of epileptic patients.
    Journal of clinical and experimental neuropsychology, 1990, Volume: 12, Issue:5

    Topics: Amobarbital; Attention; Brain Damage, Chronic; Brain Mapping; Dominance, Cerebral; Epilepsies, Parti

1990
Visual half-field testing for defining cerebral hemisphere speech laterality.
    Acta neurologica Scandinavica, 1990, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Amobarbital; Dominance, Cerebral; Epilepsies, Partial; Epilepsy, Temporal Lobe; F

1990
Cerebral language lateralization: evidence from intracarotid amobarbital testing.
    Neuropsychologia, 1990, Volume: 28, Issue:8

    Topics: Amobarbital; Brain Mapping; Carotid Artery, Internal; Dominance, Cerebral; Epilepsy, Temporal Lobe;

1990
Intracranial EEG changes during intracarotid sodium amobarbital (WADA) test in epileptic patients.
    The Japanese journal of psychiatry and neurology, 1990, Volume: 44, Issue:2

    Topics: Adult; Amobarbital; Brain Mapping; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potential

1990
Crossed cerebellar diaschisis in intracarotid sodium amytal procedures: a SPECT study.
    Acta neurologica Scandinavica, 1990, Volume: 81, Issue:5

    Topics: Adolescent; Adult; Amobarbital; Carotid Artery, Internal; Cerebellar Diseases; Cerebrovascular Circu

1990
Brain perfusion with intracarotid injection of 99mTc-HM-PAO in partial epilepsy during amobarbital testing.
    European journal of nuclear medicine, 1990, Volume: 16, Issue:8-10

    Topics: Adult; Amobarbital; Brain; Carotid Artery, Internal; Cerebral Angiography; Cerebrovascular Circulati

1990
Acoustic analysis of affective prosody during right-sided Wada Test: a within-subjects verification of the right hemisphere's role in language.
    Brain and language, 1988, Volume: 33, Issue:1

    Topics: Adult; Affect; Amobarbital; Aphasia; Dominance, Cerebral; Epilepsy, Temporal Lobe; Female; Humans; M

1988
Short-term and long-term memory deficit following intracarotid Amytal injection: further support for the memory consolidation hypothesis.
    Brain and cognition, 1989, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Amnesia, Retrograde; Amobarbital; Aphasia; Brain; Carotid Arteries; Dominance, Ce

1989
Perceptual asymmetry on the dichotic fused words test and cerebral speech lateralization determined by the carotid sodium amytal test.
    Neuropsychologia, 1989, Volume: 27, Issue:10

    Topics: Adult; Amobarbital; Aphasia; Attention; Carotid Arteries; Dichotic Listening Tests; Dominance, Cereb

1989
Selective posterior cerebral artery injection of amytal: new method of preoperative memory testing.
    Mayo Clinic proceedings, 1989, Volume: 64, Issue:8

    Topics: Adolescent; Adult; Amobarbital; Carotid Artery, Internal; Cerebral Angiography; Cerebral Arteries; E

1989
Barbiturate effects on EEG abnormality in complex partial epilepsy.
    Journal of neurology, 1989, Volume: 236, Issue:1

    Topics: Adult; Amobarbital; Barbiturates; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; M

1989
[Preoperative diagnosis: the Wada test with SPECT control for localizing brain function in therapy-refractory epilepsy].
    Neurochirurgia, 1988, Volume: 31, Issue:3

    Topics: Adult; Amobarbital; Brain; Cerebrovascular Circulation; Dominance, Cerebral; Epilepsy; Epilepsy, Tem

1988
Selective posterior cerebral artery Amytal test for evaluating memory function before surgery for temporal lobe seizure.
    Radiology, 1988, Volume: 168, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Carotid Artery, Internal; Cerebral Angiography; Cerebral Arteries; D

1988
Whither the Wada?
    Radiology, 1988, Volume: 168, Issue:3

    Topics: Amobarbital; Carotid Artery, Internal; Dominance, Cerebral; Epilepsy, Temporal Lobe; Humans; Memory

1988
Hemisphere memory of concrete and abstract information determined with the intracarotid Sodium Amytal test.
    Epilepsy research, 1987, Volume: 1, Issue:3

    Topics: Adult; Amobarbital; Brain; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Injection

1987
Lateralisation of memory functions in epileptic patients by use of the sodium amytal (Wada) technique.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Aged; Amobarbital; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female

1987
Memory for objects presented soon after intracarotid amobarbital sodium injections in patients with medically intractable complex partial seizures.
    Neurology, 1986, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Amobarbital; Attention; Brain; Carotid Artery, Internal; Child; Confusion; Electr

1986
Disorders of learning and memory after temporal lobe lesions in man.
    Clinical neurosurgery, 1972, Volume: 19

    Topics: Adult; Amnesia; Amobarbital; Brain Diseases; Epilepsy, Temporal Lobe; Hippocampus; Humans; Learning

1972