amobarbital has been researched along with Epilepsies, Partial in 32 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of surgical treatment of intractable epilepsy seizures in a group of patients investigated with the intracarotid amobarbital-pentylenetetrazol EEG test were analyzed." | 3.65 | Role of the intracarotid amobarbital-pentylenetetrazol EEG test in the diagnosis and surgical treatment of patients with complex seizure problems. ( Altuzarra, A; Garretson, H; Gloor, P; Rasmussen, T, 1976) |
| "Intractable occipital lobe epilepsy remains a surgical challenge." | 1.36 | Intractable occipital lobe epilepsy: clinical characteristics and surgical treatment. ( Bujarski, KA; Darcey, TM; Duhaime, AC; Gilbert, KL; Holmes, GL; Jobst, BC; Morse, RP; Roberts, DW; Thadani, VM; Williamson, PD, 2010) |
| "We compared children with left-sided focal epilepsy and atypical (i." | 1.32 | Clinical and neuropsychological characteristics of pediatric epilepsy patients with atypical language dominance. ( Elger, CE; Gleissner, U; Helmstaedter, C; Kuczaty, S; Kurthen, M; Linke, DB; Sassen, R; Urbach, H, 2003) |
| " In cases with poor memory results high inattention scores may speak in favour of preoperative hemisphere memory testing or a repeat injection with reduced Amytal dosage before deciding upon the extent of a planned resection." | 1.28 | A compound score for estimating the influence of inattention and somnolence during the intracarotid amobarbital test. ( Bilting, M; Hagberg, I; Hedström, A; Malmgren, K; Silfvenius, H; Starmark, JE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (28.13) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| English, J | 1 |
| Davis, B | 1 |
| Jobst, BC | 1 |
| Williamson, PD | 1 |
| Thadani, VM | 1 |
| Gilbert, KL | 1 |
| Holmes, GL | 1 |
| Morse, RP | 1 |
| Darcey, TM | 1 |
| Duhaime, AC | 1 |
| Bujarski, KA | 1 |
| Roberts, DW | 1 |
| Urbach, H | 2 |
| Von Oertzen, J | 1 |
| Klemm, E | 1 |
| Koenig, R | 1 |
| Linke, DB | 3 |
| Kurthen, M | 3 |
| Schramm, J | 1 |
| Elger, CE | 3 |
| Loddenkemper, T | 1 |
| Foldvary, N | 1 |
| Raja, S | 1 |
| Neme, S | 1 |
| Lüders, HO | 1 |
| Lee, GP | 1 |
| Park, YD | 2 |
| Westerveld, M | 1 |
| Hempel, A | 1 |
| Blackburn, LB | 1 |
| Loring, DW | 1 |
| Burneo, JG | 1 |
| Knowlton, RC | 1 |
| Gomez, C | 1 |
| Martin, R | 1 |
| Kuzniecky, RI | 1 |
| Gleissner, U | 1 |
| Sassen, R | 1 |
| Kuczaty, S | 1 |
| Helmstaedter, C | 2 |
| Papanicolaou, AC | 1 |
| Simos, PG | 1 |
| Castillo, EM | 1 |
| Breier, JI | 1 |
| Sarkari, S | 1 |
| Pataraia, E | 1 |
| Billingsley, RL | 1 |
| Buchanan, S | 1 |
| Wheless, J | 1 |
| Maggio, V | 1 |
| Maggio, WW | 1 |
| Valton, L | 1 |
| Mascott, CR | 1 |
| Pfefferkorn, T | 1 |
| Hundt, C | 1 |
| Arnold, S | 1 |
| Missler, U | 1 |
| Noachtar, S | 1 |
| Hamann, GF | 1 |
| Lanzenberger, R | 1 |
| Wiest, G | 1 |
| Geissler, A | 1 |
| Barth, M | 1 |
| Ringl, H | 1 |
| Wöber, C | 1 |
| Gartus, A | 1 |
| Baumgartner, C | 1 |
| Beisteiner, R | 1 |
| Silfvenius, H | 4 |
| Nilsson, LG | 1 |
| Wale, J | 1 |
| Geffen, G | 1 |
| Sperling, MR | 1 |
| Saykin, AJ | 1 |
| Glosser, G | 2 |
| Moran, M | 1 |
| French, JA | 1 |
| Brooks, M | 1 |
| O'Connor, MJ | 1 |
| Hoffman, JM | 1 |
| Radtke, RA | 1 |
| DeLong, GR | 1 |
| Perrine, K | 1 |
| Gershengorn, J | 1 |
| Brown, ER | 1 |
| Choi, IS | 1 |
| Luciano, DJ | 1 |
| Devinsky, O | 1 |
| Selwa, LM | 1 |
| Buchtel, HA | 1 |
| Henry, TR | 1 |
| Swearer, JM | 1 |
| Kane, KJ | 1 |
| Phillips, CA | 1 |
| Weaver, JP | 1 |
| Anderson, TD | 1 |
| Lavoie, MS | 1 |
| Spencer, DC | 1 |
| Morrell, MJ | 1 |
| Risinger, MW | 1 |
| Chiaravalloti, ND | 1 |
| Acharya, VJ | 1 |
| Acharya, JN | 1 |
| Tegeler, CH | 1 |
| Morris, P | 1 |
| Meads, D | 1 |
| O'Donovan, CA | 1 |
| Shale, JH | 1 |
| Murray, GB | 1 |
| Milner, B | 1 |
| Gloor, P | 2 |
| Rasmussen, T | 1 |
| Altuzarra, A | 1 |
| Garretson, H | 1 |
| Malmgren, K | 1 |
| Bilting, M | 1 |
| Hagberg, I | 1 |
| Hedström, A | 1 |
| Starmark, JE | 1 |
| Christianson, SA | 2 |
| Säisä, J | 2 |
| Zatorre, RJ | 1 |
| Rey, M | 1 |
| Dellatolas, G | 1 |
| Bancaud, J | 1 |
| Talairach, J | 1 |
| Lloyd-Smith, DL | 1 |
3 reviews available for amobarbital and Epilepsies, Partial
| Article | Year |
|---|---|
[What is the current role of a Wada test in the pre-surgical work-up of pharmacologically intractable epilepsy in adults?].
Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Anticonvulsants; Brain Mapping; Carotid Arteries; D | 2004 |
Contributions of electroencephalography and electrocorticography to the neurosurgical treatment of the epilepsies.
Topics: Amobarbital; Bemegride; Cerebral Cortex; Electric Stimulation; Electrodes; Electrodes, Implanted; El | 1975 |
The electroencephalogram as a diagnostic aid in neurosurgery: a review.
Topics: Adult; Age Factors; Amobarbital; Brain Diseases; Brain Injuries; Brain Neoplasms; Child; Child, Pres | 1969 |
2 trials available for amobarbital and Epilepsies, Partial
| Article | Year |
|---|---|
Predictors of outcome after anterior temporal lobectomy: the intracarotid amobarbital test.
Topics: Adolescent; Adult; Amobarbital; Carotid Arteries; Carotid Artery, Internal; Child; Electroencephalog | 1994 |
Predictive value of the intracarotid amobarbital test in bihemispheric seizure onset.
Topics: Adult; Amobarbital; Carotid Arteries; Diagnosis, Differential; Electroencephalography; Epilepsies, P | 1999 |
27 other studies available for amobarbital and Epilepsies, Partial
| Article | Year |
|---|---|
Case report: Death associated with stroke following intracarotid amobarbital testing.
Topics: Adult; Amobarbital; Cerebral Angiography; Epilepsies, Partial; Fatal Outcome; Humans; Infarction, Mi | 2010 |
Intractable occipital lobe epilepsy: clinical characteristics and surgical treatment.
Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Electrodes, Implanted; Electroencephalography; Epilep | 2010 |
Selective middle cerebral artery Wada tests as a part of presurgical evaluation in patients with drug-resistant epilepsies.
Topics: Adolescent; Adult; Amobarbital; Brain; Brain Mapping; Child; Child, Preschool; Epilepsies, Partial; | 2002 |
Ictal urinary urge: further evidence for lateralization to the nondominant hemisphere.
Topics: Adult; Amobarbital; Awareness; Child; Dominance, Cerebral; Electroencephalography; Epilepsies, Parti | 2003 |
Wada memory performance predicts seizure outcome after epilepsy surgery in children.
Topics: Adolescent; Amobarbital; Anterior Temporal Lobectomy; Cerebral Cortex; Child; Child, Preschool; Domi | 2003 |
Confirmation of nonconvulsive limbic status epilepticus with the sodium amytal test.
Topics: Adult; Amobarbital; Cerebral Cortex; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Elec | 2003 |
Clinical and neuropsychological characteristics of pediatric epilepsy patients with atypical language dominance.
Topics: Adolescent; Amobarbital; Cerebral Cortex; Child; Dominance, Cerebral; Electroencephalography; Electr | 2003 |
Magnetocephalography: a noninvasive alternative to the Wada procedure.
Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Carotid Arteries; Cerebral Cortex; Child; Dominance, | 2004 |
Contralateral cerebral blood flow velocity changes after intracarotid amobarbital injection.
Topics: Adult; Amobarbital; Blood Flow Velocity; Carotid Arteries; Cerebrovascular Circulation; Epilepsies, | 2004 |
FMRI reveals functional cortex in a case of inconclusive Wada testing.
Topics: Adult; Amobarbital; Brain Mapping; Cerebral Cortex; Dominance, Cerebral; Epilepsies, Partial; Evoked | 2005 |
[The amytal test--a diagnostic aid in epileptic surgery].
Topics: Adolescent; Adult; Amobarbital; Brain; Dominance, Cerebral; Epilepsies, Partial; Female; Humans; Mal | 1984 |
Dichotic monitoring as a test of hemispheric dominance in cases of epilepsy.
Topics: Adolescent; Adult; Amobarbital; Dominance, Cerebral; Epilepsies, Partial; Epilepsy; Epilepsy, Tempor | 1981 |
Focal cerebral metabolic abnormality in a patient with continuous spike waves during slow-wave sleep.
Topics: Amobarbital; Blood Glucose; Brain; Cerebral Cortex; Child; Child Behavior Disorders; Deoxyglucose; D | 1994 |
Material-specific memory in the intracarotid amobarbital procedure.
Topics: Amobarbital; Discriminant Analysis; Dominance, Cerebral; Epilepsies, Partial; Epilepsy, Temporal Lob | 1993 |
Patterns of language dominance in focal left and right hemisphere epilepsies: relation to MRI findings, EEG, sex, and age at onset of epilepsy.
Topics: Age of Onset; Amobarbital; Cerebral Cortex; Chi-Square Distribution; Cognition Disorders; Cross-Sect | 1997 |
Electrocerebral recovery during the intracarotid amobarbital procedure: influence of interval between injections.
Topics: Amobarbital; Brain; Carotid Arteries; Delta Rhythm; Electroencephalography; Epilepsies, Partial; Fem | 1997 |
The role of the intracarotid amobarbital procedure in evaluation of patients for epilepsy surgery.
Topics: Adolescent; Adult; Amobarbital; Brain; Carotid Artery, Internal; Child; Electroencephalography; Epil | 2000 |
Material-specific memory changes after anterior temporal lobectomy as predicted by the intracarotid amobarbital test.
Topics: Adult; Amobarbital; Carotid Artery, Internal; Epilepsies, Partial; Epilepsy, Temporal Lobe; Function | 2001 |
Transcranial Doppler ultrasound: a new method of monitoring hemispheric anesthetization during the intracarotid amobarbital procedure.
Topics: Amobarbital; Blood Flow Velocity; Brain; Carotid Arteries; Electroencephalography; Epilepsies, Parti | 2002 |
Psychiatric presentation of epilepsia cursiva.
Topics: Adolescent; Amobarbital; Electroencephalography; Epilepsies, Partial; Humans; Male; Runaway Behavior | 1978 |
Psychological aspects of focal epilepsy and its neurosurgical management.
Topics: Adolescent; Adult; Amobarbital; Auditory Perception; Child; Child, Preschool; Cognition; Epilepsies, | 1975 |
Role of the intracarotid amobarbital-pentylenetetrazol EEG test in the diagnosis and surgical treatment of patients with complex seizure problems.
Topics: Adolescent; Amobarbital; Brain; Carotid Arteries; Cerebrovascular Circulation; Depression, Chemical; | 1976 |
A compound score for estimating the influence of inattention and somnolence during the intracarotid amobarbital test.
Topics: Adult; Amobarbital; Attention; Consciousness; Epilepsies, Partial; Female; Humans; Male; Memory; Mid | 1992 |
Hemisphere memory differences in Sodium Amytal testing of epileptic patients.
Topics: Amobarbital; Attention; Brain Damage, Chronic; Brain Mapping; Dominance, Cerebral; Epilepsies, Parti | 1990 |
Visual half-field testing for defining cerebral hemisphere speech laterality.
Topics: Adolescent; Adult; Amobarbital; Dominance, Cerebral; Epilepsies, Partial; Epilepsy, Temporal Lobe; F | 1990 |
Perceptual asymmetry on the dichotic fused words test and cerebral speech lateralization determined by the carotid sodium amytal test.
Topics: Adult; Amobarbital; Aphasia; Attention; Carotid Arteries; Dichotic Listening Tests; Dominance, Cereb | 1989 |
Hemispheric lateralization of motor and speech functions after early brain lesion: study of 73 epileptic patients with intracarotid amytal test.
Topics: Adolescent; Adult; Amobarbital; Brain Damage, Chronic; Carotid Arteries; Child; Dominance, Cerebral; | 1988 |