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amobarbital and Dementia Praecox

amobarbital has been researched along with Dementia Praecox in 49 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Research Excerpts

ExcerptRelevanceReference
"Loxapine succinate was compared to chlorpromazine in a 12-week double-blind study of 50 hospitalized chronic schizophrenic patients."6.64Loxapine succinate: a controlled double-blind study in chronic schizophrenia. ( Schiele, BC, 1975)
" The effectiveness of alternate agents sodium amytal and chloral hydrate when initiating clozapine was evaluated in a group of 15 patients suffering from schizophrenia."3.69The use of chloral hydrate and sodium amytal during clozapine initiation. ( Dalby, JT; Dickson, RA; Williams, R, 1994)
"Eighty-six patients with acute psychotic exacerbations were treated with fixed dosage regimens of oral fluphenazine up to 10-30 mg/day in randomized, double-blind studies."2.67Acute dystonia during fixed-dose neuroleptic treatment. ( Friedman, E; Levinson, DF; Lo, ES; Simpson, GM; Singh, H, 1990)
"Loxapine succinate was compared to chlorpromazine in a 12-week double-blind study of 50 hospitalized chronic schizophrenic patients."2.64Loxapine succinate: a controlled double-blind study in chronic schizophrenia. ( Schiele, BC, 1975)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199046 (93.88)18.7374
1990's3 (6.12)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GOTTLIEB, JS4
KNOTT, JR1
KIMBLE, LL1
FEATHERSTONE, RM1
CARTER, HR1
MAINORD, WA1
KOBETS, AV1
COHEN, BD5
SENF, R4
HUSTON, PE4
ZUCKERMAN, M1
IZNER, S1
LEISER, R1
PENNES, HH1
FERRIO, L1
RASHKIS, HA1
SMARR, ER1
FULCHER, JH1
GALLAGHER, WJ1
PFEIFFER, CC1
BROADHURST, A1
HURST, L1
BRUNE, GG1
KOBAYASHI, T1
BULL, C1
TOURLENTES, TT1
HIMWICH, HE1
ROSENBAUM, G2
LUBY, ED2
LYNN, R1
WHITAKER, LH1
PROUT, CT1
DAVISON, K1
SHAGASS, C2
SCHWARTZ, M1
BAZHIN, EF1
SMALL, JG1
SMALL, IF1
YELEN, D1
DELAY, J1
ROUBLEFF, I1
Kutsenok, BM1
d'Elia, G1
Perris, C1
Endo, M1
Perry, JC1
Jacobs, D1
Fisman, M1
Dickson, RA1
Williams, R1
Dalby, JT1
Dysken, MW1
Kooser, JA1
Haraszti, JS1
Davis, JM1
Cervantes, P1
Lal, S1
Smith, F1
Guyda, H1
Schiele, BC1
Singh, H1
Levinson, DF1
Simpson, GM1
Lo, ES1
Friedman, E1
Wyant, M1
Diamond, BI1
O'Neal, E1
Sloan, A1
Borison, RL1
Weller, EB1
Weller, RA1
Fristad, MA1
Barker, ET1
Mason, MH1
NeÄ­koya, M1
Hollender, MH1
Steckler, PP1
Tan, BK1
Snodgrass, RE1
Lader, MH1
Lichko, AE1
Braverman, LB1
Lehmann, HE2
Ban, TA2
Kral, VA2
Silver, D1
Woodruff, R1

Reviews

3 reviews available for amobarbital and Dementia Praecox

ArticleYear
RUSSIAN THEORY AND RESEARCH ON SCHIZOPHRENIA.
    Psychological bulletin, 1963, Volume: 60

    Topics: Amobarbital; Bromides; Caffeine; Cerebral Cortex; Chlorpromazine; Conditioning, Psychological; Convu

1963
EEG and evoked potentials in the psychoses.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Adjustment Disorders; Alpha Rhythm; Amobarbital; Bipolar Disorder; Depression; Electroencephalograph

1975
Physiological measures in psychiatry.
    The Scientific basis of medicine annual reviews, 1971

    Topics: Adaptation, Psychological; Amobarbital; Animals; Anxiety; Arousal; Blood Pressure; Depression; Elect

1971

Trials

5 trials available for amobarbital and Dementia Praecox

ArticleYear
Clinical usefulness of sodium amobarbital interviewing.
    Archives of general psychiatry, 1979, Volume: 36, Issue:7

    Topics: Adult; Amobarbital; Brief Psychiatric Rating Scale; Communication; Depression; Double-Blind Method;

1979
Loxapine succinate: a controlled double-blind study in chronic schizophrenia.
    Diseases of the nervous system, 1975, Volume: 36, Issue:7

    Topics: Adult; Aged; Amobarbital; Analysis of Variance; Chemical Phenomena; Chemistry; Chlorpromazine; Clini

1975
Acute dystonia during fixed-dose neuroleptic treatment.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Adult; Amobarbital; Chloral Hydrate; Dose-Response Relationship, Drug; Drug Administration Schedule;

1990
The use of midazolam in acutely agitated psychiatric patients.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:1

    Topics: Adult; Amobarbital; Haloperidol; Humans; Male; Midazolam; Middle Aged; Schizophrenia

1990
Psychological tests: practice effect in geriatric patients.
    Geriatrics, 1968, Volume: 23, Issue:2

    Topics: Aged; Amobarbital; Amphetamine; Carbon Dioxide; Female; Humans; Male; Mental Disorders; Middle Aged;

1968

Other Studies

41 other studies available for amobarbital and Dementia Praecox

ArticleYear
Psychopharmacologic study of schizophrenia and depression; the influence of electric convulsive therapy on the sodium amytal response of the electroencephalogram.
    The American journal of psychiatry, 1948, Volume: 104, Issue:11

    Topics: Amobarbital; Depression; Depressive Disorder; Electroconvulsive Therapy; Electroencephalography; Hum

1948
Psychopharmacologic study of schizophrenia and depressions; lactic and pyruvic acid content of the blood before and after administration of sodium amytal.
    Archives of neurology and psychiatry, 1947, Volume: 58, Issue:2

    Topics: Amobarbital; Brain; Depression; Nervous System Physiological Phenomena; Pyruvic Acid; Schizophrenia

1947
Some effects of sodium amytal on deteriorated schizophrenics.
    Journal of consulting psychology, 1953, Volume: 17, Issue:1

    Topics: Amobarbital; Barbiturates; Schizophrenia

1953
[Effect of amytal intoxication on clinical picture of schizophrenia during sleep therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1953, Volume: 53, Issue:3

    Topics: Amobarbital; Barbiturates; Schizophrenia; Sleep

1953
Effect of amobarbital (amytal) and affect on conceptual thinking in schizophrenia, depression, and neurosis.
    A.M.A. archives of neurology and psychiatry, 1954, Volume: 71, Issue:2

    Topics: Amobarbital; Barbiturates; Depression; Emotions; Humans; Neurotic Disorders; Schizophrenia; Schizoph

1954
Sodium amytal Rorschach in incipient schizophrenia.
    Diseases of the nervous system, 1954, Volume: 15, Issue:2

    Topics: Amobarbital; Barbiturates; Humans; Rorschach Test; Schizophrenia; Schizophrenic Psychology; Schizoty

1954
Clinical reactions of schizophrenics to sodium amytal, pervitin hydrochloride, mescaline sulfate, and d-lysergic acid diethylamide (LSD25).
    The Journal of nervous and mental disease, 1954, Volume: 119, Issue:2

    Topics: Amobarbital; Barbiturates; Ephedrine; Ergot Alkaloids; Humans; Lysergic Acid Diethylamide; Mescaline

1954
Perceptual accuracy in schizophrenia, depression, and neurosis, and effects of amytal.
    Journal of abnormal psychology, 1956, Volume: 52, Issue:3

    Topics: Amobarbital; Amphetamine; Amphetamines; Barbiturates; Depression; Depressive Disorder; Humans; Neuro

1956
[Study of the effect of RP 4560 alone and with barbiturates in cases of schizophrenic psychoses].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1957, Jan-01, Volume: 81, Issue:1

    Topics: Amobarbital; Barbiturates; Chlorpromazine; Humans; Mental Disorders; Psychotic Disorders; Schizophre

1957
Drug and milieu effects with chronic schizophrenics.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 78, Issue:1

    Topics: Amobarbital; Catatonia; Methylphenidate; Reserpine; Schizophrenia; Trihexyphenidyl

1957
Comparative lucid intervals after amobarbital, CO2, and arecoline in the chronic schizophrenic.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 78, Issue:4

    Topics: Amobarbital; Arecoline; Carbon Dioxide; Humans; Parasympathomimetics; Schizophrenia

1957
Experimental studies of the mental speed of schizophrenics. I. Effects of a stimulant and a depressant drug.
    The Journal of mental science, 1958, Volume: 104, Issue:437

    Topics: Amobarbital; Amphetamine; Amphetamines; Central Nervous System Stimulants; Humans; Learning; Schizop

1958
Amylobarbitone sodium interviews with schizophrenic patients.
    The Psychiatric quarterly, 1960, Volume: 34

    Topics: Amobarbital; Humans; Schizophrenia; Sodium

1960
Relevance of drug-induced extrapyramidal reactions to behavioral changes during neuroleptic treatment. II. Combined treatment with trifluoperazine-amobarbital.
    Comprehensive psychiatry, 1962, Volume: 3

    Topics: Amobarbital; Antipsychotic Agents; Basal Ganglia Diseases; Combined Modality Therapy; Disease; Extra

1962
Comparison of phencyclidine hydrochloride (Sernyl) with other drugs. Simulation of schizophrenic performance with phencyclidine hydrochloride (Sernyl), lysergic acid diethylamide (LSD-25), and amobarbital (Amytal) sodium; II. Symbolic and sequential think
    Archives of general psychiatry, 1962, Volume: 6

    Topics: Amobarbital; Anesthetics; Humans; Lysergic Acid Diethylamide; Phencyclidine; Schizophrenia; Sodium

1962
LYSERGIC ACID DIETHYLAMIDE IN PSYCHOTHERAPY. I: CLINICAL ASPECTS.
    The Medical journal of Australia, 1964, Jan-04, Volume: 1

    Topics: Amobarbital; Antisocial Personality Disorder; Chlorpromazine; Humans; Lysergic Acid Diethylamide; Ne

1964
REACTIONS TO USE OF AMPHETAMINES AS OBSERVED IN A PSYCHIATRIC HOSPITAL.
    New York state journal of medicine, 1964, May-15, Volume: 64

    Topics: Alcoholism; Amobarbital; Amphetamine; Amphetamines; Barbiturates; Dextroamphetamine; Hospitals, Psyc

1964
EPISODIC DEPERSONALIZATION; OBSERVATIONS ON 7 PATIENTS.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Alcoholic Beverages; Amitriptyline; Amobarbital; Cochlea; Convulsive Therapy; Depersonalization; Dep

1964
EVOKED POTENTIAL STUDIES IN PSYCHIATRIC PATIENTS.
    Annals of the New York Academy of Sciences, 1964, May-08, Volume: 112

    Topics: Amobarbital; Antisocial Personality Disorder; Biomedical Research; Bipolar Disorder; Electric Stimul

1964
[APROPOS OF THE USE OF THE AMYTAL-CAFFEINE DISINHIBITION IN CHRONIC SCHIZOPHRENIA IN PSYCHOPATHOLOGICAL STUDY AND PROGNOSTIC EVALUATION OF THERAPY].
    Voprosy psikhiatrii i nevropatologii; sbornik trudov, 1964, Volume: 10

    Topics: Amobarbital; Caffeine; Humans; Mental Disorders; Prognosis; Psychopathology; Schizophrenia

1964
RE-EVALUATION OF CLINICAL EEG FINDINGS IN SCHIZOPHRENIA.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Amobarbital; Diagnosis; Drug Therapy; Electroencephalography; Humans; Prognosis; Schizophrenia; Tran

1965
Thinking deficit in schizophrenia and changes with amytal.
    Journal of abnormal psychology, 1955, Volume: 50, Issue:3

    Topics: Amobarbital; Barbiturates; Humans; Schizophrenia; Schizophrenic Psychology; Thinking

1955
Comparison of sernyl with other drugs: simulation of schizophrenic performance with sernyl, LSD-25, and amobarbital (amytal) sodium; I. Attention, motor function, and proprioception.
    A.M.A. archives of general psychiatry, 1959, Volume: 1

    Topics: Amobarbital; Attention; Humans; Lysergic Acid Diethylamide; Phencyclidine; Piperidines; Propriocepti

1959
Psychopathology of schizophrenia and depression. I. Effect of amytal and amphetamine sulfate on level and maintenance of attention.
    The American journal of psychiatry, 1952, Volume: 109, Issue:2

    Topics: Aged; Amobarbital; Amphetamine; Attention; Depression; Depressive Disorder; Humans; Psychopathology;

1952
[A case of reticence in a hebephrenic; action of sodium amytal].
    Annales medico-psychologiques, 1950, Volume: 108, Issue:1 4

    Topics: Amobarbital; Narcotherapy; Schizophrenia; Schizophrenia, Disorganized

1950
[On the differential diagnosis of relapsing schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:9

    Topics: Adolescent; Adult; Amobarbital; Catatonia; Delirium; Depression; Diagnosis, Differential; Female; Ha

1966
The reproducibility of the sedation threshold in chronic psychotics.
    International journal of neuropsychiatry, 1967, Volume: 3, Issue:2

    Topics: Adult; Aged; Amobarbital; Electroencephalography; Humans; Male; Middle Aged; Schizophrenia; Sleep

1967
[A study on amobarbital-induced sleep in schizophrenics. Correlation with the effects of pharmacotherapy].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1967, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Amobarbital; Chlorpromazine; Female; Humans; Male; Schizophrenia; Sleep

1967
Overview: clinical applications of the Amytal interview in psychiatric emergency settings.
    The American journal of psychiatry, 1982, Volume: 139, Issue:5

    Topics: Adult; Aged; Amnesia; Amobarbital; Catatonia; Combat Disorders; Depressive Disorder; Diagnosis, Diff

1982
Pseudodementia and schizophrenia.
    The American journal of psychiatry, 1982, Volume: 139, Issue:6

    Topics: Aged; Alzheimer Disease; Amobarbital; Dementia; Factitious Disorders; Female; Humans; Schizophrenia

1982
The use of chloral hydrate and sodium amytal during clozapine initiation.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:3

    Topics: Adult; Amobarbital; Chloral Hydrate; Clozapine; Dose-Response Relationship, Drug; Drug Administratio

1994
Dopaminergic function in two patients with catalepsy.
    Acta psychiatrica Scandinavica, 1977, Volume: 55, Issue:3

    Topics: Adult; Amobarbital; Apomorphine; Catalepsy; Female; Growth Hormone; Humans; Injections, Intravenous;

1977
Use of sodium amytal interviews in prepubertal children: indications, procedure, and clinical utility.
    Journal of the American Academy of Child Psychiatry, 1985, Volume: 24, Issue:6

    Topics: Amobarbital; Child; Depression; Developmental Disabilities; Female; Humans; Male; Mental Disorders;

1985
Bubber behind bars.
    Canadian Psychiatric Association journal, 1968, Volume: 13, Issue:1

    Topics: Amobarbital; Antisocial Personality Disorder; Attitude to Health; Audiovisual Aids; Communication; D

1968
[Treatment of acute schizophrenia with antibiotics, gamma-globulin and vitamins].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Amobarbital; Anti-Bacterial Agents; Antimalarials; Ascorbic Acid;

1966
Multiple sclerosis and schizophrenia: a case report.
    Psychiatry in medicine, 1972, Volume: 3, Issue:3

    Topics: Adult; Amobarbital; Diagnosis, Differential; Electroconvulsive Therapy; Female; Humans; Multiple Scl

1972
Autonomic correlates of the sedation threshold.
    Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:3

    Topics: Adult; Amobarbital; Analysis of Variance; Autonomic Nervous System; Depression; Dose-Response Relati

1973
Psychiatric problems in the hospital emergency room.
    The Journal of the Indiana State Medical Association, 1974, Volume: 67, Issue:4

    Topics: Affective Symptoms; Amobarbital; Chlordiazepoxide; Chlorpromazine; Emergency Service, Hospital; Homi

1974
[Protracted (unaffected by glucose) insulin comas, their cause, clinical picture and treatment].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:2

    Topics: Amobarbital; Barbiturates; Chlorpromazine; Convulsive Therapy; Depressive Disorder, Major; Encephali

1970
Experimental geriatrics. Selection and prediction of therapeutic responsiveness in geriatric patients.
    Canadian Psychiatric Association journal, 1968, Volume: 13, Issue:6

    Topics: Aged; Amobarbital; Analysis of Variance; Carbon Dioxide; Hospitalization; Humans; Methamphetamine; N

1968
The diagnostic use of the amylobarbitone interview among patients with psychotic illnesses.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:488

    Topics: Adult; Amobarbital; Bipolar Disorder; Depressive Disorder, Major; Humans; Injections, Intravenous; I

1966