amobarbital has been researched along with Creutzfeldt-Jakob Syndrome in 3 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of rapid intracarotid injection of 20 to 100 mg of sodium amobarbital were studied in three patients with bilateral myoclonic status epilepticus due to Jakob-Creutzfeldt disease, sequelae to anoxic encephalopathy, and hepatic coma, respectively." | 7.65 | Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus. ( Chatrian, GE; McCutchen, CB; Vignaendra, V, 1977) |
| "The effects of rapid intracarotid injection of 20 to 100 mg of sodium amobarbital were studied in three patients with bilateral myoclonic status epilepticus due to Jakob-Creutzfeldt disease, sequelae to anoxic encephalopathy, and hepatic coma, respectively." | 3.65 | Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus. ( Chatrian, GE; McCutchen, CB; Vignaendra, V, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roy-Byrne, P | 1 |
| Edelstein, C | 1 |
| McCutchen, CB | 1 |
| Vignaendra, V | 1 |
| Chatrian, GE | 1 |
| Lee, RG | 1 |
| Blair, RD | 1 |
3 other studies available for amobarbital and Creutzfeldt-Jakob Syndrome
| Article | Year |
|---|---|
Identifying organic brain disease by amobarbital sodium interview: diagnostic pitfalls.
Topics: Adult; Amobarbital; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Humans; Male; Neurocognitiv | 1982 |
Electrographic and clinical effects of intracarotid sodium amobarbital on bilateral myoclonic status epilepticus.
Topics: Aged; Amobarbital; Carotid Artery, Internal; Cerebral Cortex; Creutzfeldt-Jakob Syndrome; Electroenc | 1977 |
Evolution of EEG and visual evoked response changes in Jakob-Creutzfeldt disease.
Topics: Amobarbital; Brain; Cortical Synchronization; Creutzfeldt-Jakob Syndrome; Electroencephalography; Ev | 1973 |