amobarbital and Coma
amobarbital has been researched along with Coma in 12 studies
Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " A condition for antidote effect of the Krebs intermediate was sufficiently high dosage (5 mmol/kg), further dose increase made no odds." | 1.32 | Intermediates of Krebs cycle correct the depression of the whole body oxygen consumption and lethal cooling in barbiturate poisoning in rat. ( Ivnitsky, JJ; Malakhovsky, VN; Rejniuk, VL; Schäfer, TV, 2004) |
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| SUNSHINE, P | 1 |
| YAFFE, SJ | 1 |
| DOBROVOLSKAIA, TI | 1 |
| POROSHINA, IuA | 1 |
| KORKINA, MV | 1 |
| MULLAN, D | 1 |
| PLATTS, M | 1 |
| RIDGWAY, B | 1 |
| STARK, JE | 1 |
| BETHUNE, DW | 1 |
| Ivnitsky, JJ | 1 |
| Schäfer, TV | 1 |
| Malakhovsky, VN | 1 |
| Rejniuk, VL | 1 |
| Goulon, M | 1 |
| Nouailhat, F | 1 |
| Lévy-Alcover, MA | 1 |
| Dordain, G | 1 |
| Richard, B | 1 |
| Honer, WG | 1 |
| Rosenberg, RG | 1 |
| Turey, M | 1 |
| Fisher, WA | 1 |
| Carroll, BJ | 1 |
| Mandy, S | 1 |
| Ackerman, AB | 1 |
| Fournier, E | 1 |
| Kaloyanova, F | 1 |
| Treich, I | 1 |
| Capelle, N | 1 |
| Lous, P | 1 |
Other Studies
12 other studies available for amobarbital and Coma
| Article | Year |
|---|---|
AMITRIPTYLINE POISONING. CLINICAL AND PATHOLOGICAL FINDINGS IN A FATAL CASE.
Topics: Amitriptyline; Amobarbital; Antidepressive Agents; Apnea; Arrhythmias, Cardiac; Coma; Dialysis; Flui | 1963 |
[TOXIC ENCEPHALOPATHY DEVELOPED AFTER INSULIN INTOXICATION].
Topics: Amobarbital; Brain Diseases; Coma; Insulin; Insulin Coma; Neurotoxicity Syndromes; Toxicology | 1963 |
BARBITURATE INTOXICATION.
Topics: Amobarbital; Barbiturates; Coma; Diagnosis; Electrocardiography; Hypnotics and Sedatives; Hypoxia, B | 1965 |
AMITRIPTYLINE POISONING.
Topics: Amitriptyline; Amobarbital; Barbiturates; Coma; Depression; Depressive Disorder; Diuresis; Drug Ther | 1965 |
Intermediates of Krebs cycle correct the depression of the whole body oxygen consumption and lethal cooling in barbiturate poisoning in rat.
Topics: Amobarbital; Animals; Antidotes; Body Temperature; Citric Acid Cycle; Coma; Female; Hypnotics and Se | 2004 |
[Toxic coma with autonomic sideration, with a favorable outcome].
Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam; | 1967 |
[Drug addiction to amobarbital].
Topics: Adolescent; Amobarbital; Coma; Humans; Substance-Related Disorders | 1990 |
Respiratory failure after clonazepam and amobarbital.
Topics: Amobarbital; Clonazepam; Coma; Drug Therapy, Combination; Humans; Male; Middle Aged; Psychotic Disor | 1986 |
Barbiturate overdosage: presentation with focal neurological signs.
Topics: Adult; Alcoholism; Amobarbital; Barbiturates; Basilar Artery; Bromides; Cerebral Hemorrhage; Coma; C | 1969 |
Characteristic traumatic skin lesions in drug-induced coma.
Topics: Adult; Amobarbital; Barbiturates; Biopsy; Blister; Coma; Erythema; Heroin; Humans; Male; Nalorphine; | 1970 |
[Application of gas chromatography to the identification and determination of barbiturate derivatives in the blood during acute poisoning].
Topics: Amobarbital; Barbiturates; Chemistry, Clinical; Chromatography, Gas; Coma; Humans; Methods; Methylat | 1970 |
Elimination of barbiturates.
Topics: Adult; Amobarbital; Barbiturates; Coma; Female; Humans; Pentobarbital; Phenobarbital; Thiopental | 1966 |