Page last updated: 2024-10-22

amobarbital and Chronic Insomnia

amobarbital has been researched along with Chronic Insomnia in 24 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Research Excerpts

ExcerptRelevanceReference
" Twenty-four anxious inpatients were treated with diazepam, amylobarbitone sodium and placebo in flexible dosage for 1 week."2.65A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients. ( Lader, M; Tansella, CZ; Tansella, M, 1979)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199023 (95.83)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petik, D1
Czeizel, B1
Banhidy, F1
Czeizel, AE1
HINTON, JM1
FUJIYA, Y1
TOYODA, J1
SASAKI, K1
NARITA, S1
VELGHE, R1
JONES, DP1
JONES, EA1
LAGODKA, PN1
Kraines, SH1
O'Connor, CA1
Brodbin, P1
Exton-Smith, AN1
Ansseau, M1
Diricq, S1
Pines, A1
Rooney, JF1
Arenillas, L1
Berg, S1
Dehlin, O1
Falkheden, T1
Gatzinska, R1
Nordqvist, P1
Tansella, CZ1
Tansella, M2
Lader, M1
Siciliani, O1
Burti, L1
Schiavon, M1
Zimmermann, C1
Gerna, M1
Tognoni, G1
Morselli, PL1
Kales, A1
Bixler, EO1
Tan, TL1
Scharf, MB1
Kales, JD1
Perkins, R1
Hinton, J1
Swanson, DA1
Imlah, NW1
Davies, C1
Levine, S1
Fisher, S1
Gal, P1
Bond, MR1
Pearson, IB1
Seager, CP1
Clift, AD1
Johns, MW1
Hepburn, M1
Goodyear, MD1
Meares, R1

Trials

10 trials available for amobarbital and Chronic Insomnia

ArticleYear
A double-blind trial of the new hypnotic, 'mandrax'.
    The British journal of clinical practice, 1967, Volume: 21, Issue:8

    Topics: Adult; Aged; Amobarbital; Diphenhydramine; Humans; Methaqualone; Middle Aged; Sleep Initiation and M

1967
Lormetazepam and amobarbital sodium in the outpatient treatment of insomnia: a controlled trial.
    Clinical therapeutics, 1983, Volume: 5, Issue:4

    Topics: Adult; Amobarbital; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Female; Humans;

1983
Flurazepam ('Dalmane') in the treatment of insomnia in patients with respiratory disorders.
    The Practitioner, 1976, Volume: 217, Issue:1298

    Topics: Aged; Amobarbital; Anti-Anxiety Agents; Clinical Trials as Topic; Dreams; Flurazepam; Humans; Male;

1976
A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:6

    Topics: Adult; Amobarbital; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans

1979
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Adult; Amobarbital; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics

1975
A double-blind evaluation of a new hypnotic--flurazepam hydrochloride.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-04, Volume: 47, Issue:30

    Topics: Adult; Aged; Amobarbital; Benzazepines; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypnot

1973
A controlled comparison of nitrazepam ('mogadon') with sodium amylobarbitone as a sleep-inducing agent.
    The British journal of psychiatry : the journal of mental science, 1967, Volume: 113, Issue:502

    Topics: Amobarbital; Clinical Trials as Topic; Depression; Female; Humans; Hypnotics and Sedatives; Male; Mi

1967
Flurazepam versus amobarbital as a sedative-hypnotic for geriatric patients: double-blind study.
    Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:4

    Topics: Age Factors; Aged; Amobarbital; Clinical Trials as Topic; Humans; Male; Psychological Tests; Sleep I

1969
Sleeping pills.
    British medical journal, 1970, Sep-05, Volume: 3, Issue:5722

    Topics: Amobarbital; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Humans; Middle Aged; P

1970
Factors leading to dependence on hypnotic drugs.
    British medical journal, 1972, Sep-09, Volume: 3, Issue:5827

    Topics: Amobarbital; Benzazepines; Diazepam; Family Practice; Female; Glutethimide; Humans; Hypnotics and Se

1972

Other Studies

14 other studies available for amobarbital and Chronic Insomnia

ArticleYear
A study of the risk of mental retardation among children of pregnant women who have attempted suicide by means of a drug overdose.
    Journal of injury & violence research, 2012, Volume: 4, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Amobarbital; Birth Weight; Chi-Square Distribution; Drug Combina

2012
The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients.
    British journal of pharmacology and chemotherapy, 1961, Volume: 16

    Topics: Adult; Amobarbital; Barbiturates; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male

1961
[A study on the polygraphic findings in all-night sleep recordings of the patients with insomnia].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1963, Volume: 65

    Topics: Amobarbital; Chlorpropamide; Humans; Psychological Tests; Sleep; Sleep Initiation and Maintenance Di

1963
[CONTROLLED CLINICAL TRIAL OF A SLEEP INDUCER].
    Bruxelles medical, 1963, Nov-24, Volume: 43

    Topics: Amobarbital; Barbiturates; Geriatrics; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital;

1963
DRUGS FOR INSOMNIA.
    Canadian Medical Association journal, 1963, Dec-28, Volume: 89

    Topics: Amobarbital; Child; Chloral Hydrate; Diphenhydramine; Humans; Paraldehyde; Phenobarbital; Promethazi

1963
[Clinical and somato-vegetative parallels in the treatment with interrupted sleep induced with amytal sodium].
    Uchenye zapiski. Vtoroi Moskovskii ordena Lenina gosudarstvennyi meditsinskii institut im N.I. Pirogova, 1951, Volume: 1

    Topics: Amobarbital; Autonomic Nervous System; Humans; Nervous System Physiological Phenomena; Sleep; Sleep

1951
Therapy of the chronic depressions.
    Diseases of the nervous system, 1967, Volume: 28, Issue:9

    Topics: Alcoholism; Amobarbital; Anorexia Nervosa; Antidepressive Agents; Chronic Disease; Convulsive Therap

1967
The use and abuse of hypnotics.
    Gerontologia clinica, 1967, Volume: 9, Issue:4

    Topics: Aged; Amobarbital; Antidepressive Agents; Antipyrine; Chloral Hydrate; Humans; Hypnotics and Sedativ

1967
Long term study of hypnotic medication in geriatric patients. A study of dixyrazine, nitrazepam and amylobarbitone.
    Scandinavian journal of social medicine. Supplementum, 1977, Volume: 14

    Topics: Aged; Amobarbital; Chloral Hydrate; Follow-Up Studies; Humans; Hypnotics and Sedatives; Nitrazepam;

1977
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.
    JAMA, 1974, Feb-04, Volume: 227, Issue:5

    Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi

1974
Sedative or tranquillizer? A comparison of the hypnotic effects of chlordiazepoxide and amylobarbitone sodium.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:0

    Topics: Adult; Amobarbital; Analysis of Variance; Anxiety; Chlordiazepoxide; Dose-Response Relationship, Dru

1974
Clinical experience with lorazepam in hospital patients.
    Current medical research and opinion, 1973, Volume: 1, Issue:5

    Topics: Administration, Oral; Aged; Amobarbital; Anxiety Disorders; Benzodiazepinones; Chlorobenzenes; Fatig

1973
Use of hypnotic drugs by hospital patients.
    The Medical journal of Australia, 1971, Dec-25, Volume: 2, Issue:26

    Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans

1971
The place of barbiturates in psychiatric treatment.
    The Medical journal of Australia, 1970, Jun-13, Volume: 1, Issue:24

    Topics: Abreaction; Affective Symptoms; Amobarbital; Anxiety; Barbiturates; Chlordiazepoxide; Humans; Hypnot

1970