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amobarbital and Ataxia

amobarbital has been researched along with Ataxia in 5 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Dose/response relations have been analysed for the actions of amphetamine-barbiturate mixtures on exploratory activity and ataxia in rats."3.64MUTUAL POTENTIATION OF AMPHETAMINE AND AMYLOBARBITONE MEASURED BY ACTIVITY IN RATS. ( RUSHTON, R; STEINBERG, H, 1963)
"At this dose of medazepam drowsiness or ataxia was rarely a problem."2.64Medazepam compared with amylobarbitone in treatment of anxiety. ( Kerry, RJ; McDermott, CM, 1971)
"The use of footprints to measure ataxia, with or without computer aid, is recommended as a routine test in laboratory evaluation of psychoactive drugs."1.28Computer analysis, using a digitizer, of ataxic mouse gait due to drugs. ( McBride, A; Robinson, K; Steinberg, H; Sykes, EA; Terry, P; Tillotson, H, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
EYSENCK, HJ1
EASTERBROOK, JA1
RUSHTON, R1
STEINBERG, H2
Sykes, EA1
McBride, A1
Terry, P1
Robinson, K1
Tillotson, H1
Kerry, RJ1
McDermott, CM1
Stark, P1
Henderson, JK1

Trials

1 trial available for amobarbital and Ataxia

ArticleYear
Medazepam compared with amylobarbitone in treatment of anxiety.
    British medical journal, 1971, Jan-16, Volume: 1, Issue:5741

    Topics: Amobarbital; Anxiety Disorders; Ataxia; Benzazepines; Clinical Trials as Topic; Humans; Outpatient C

1971

Other Studies

4 other studies available for amobarbital and Ataxia

ArticleYear
Drugs and personality. VI. The effects of stimulant and depressant drugs upon body sway (static ataxia).
    The Journal of mental science, 1960, Volume: 106

    Topics: Amobarbital; Amphetamine; Amphetamines; Ataxia; Central Nervous System Stimulants; Humans; Meprobama

1960
MUTUAL POTENTIATION OF AMPHETAMINE AND AMYLOBARBITONE MEASURED BY ACTIVITY IN RATS.
    British journal of pharmacology and chemotherapy, 1963, Volume: 21

    Topics: Amobarbital; Amphetamine; Animals; Ataxia; Behavior, Animal; Dextroamphetamine; Motivation; Pharmaco

1963
Computer analysis, using a digitizer, of ataxic mouse gait due to drugs.
    Journal of pharmacological methods, 1989, Volume: 21, Issue:2

    Topics: Amobarbital; Animals; Ataxia; Computers; Gait; Mice; Rats; Signal Processing, Computer-Assisted

1989
Differentiation of classes of neurosedatives using rats with septal lesions.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:6

    Topics: Amobarbital; Animals; Ataxia; Behavior, Animal; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazin

1966