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amobarbital and Arteriovenous Malformations, Cerebral

amobarbital has been researched along with Arteriovenous Malformations, Cerebral in 16 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Research Excerpts

ExcerptRelevanceReference
"In presurgical assessment of epilepsy, the intracarotid amobarbital procedure (IAP) is used for the detection of functional asymmetries of the cerebral hemispheres with respect to cognitive functions."4.78[The intra-carotid amobarbital test--indications--procedure--results]. ( Kurthen, M, 1992)
"The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure."3.75Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure. ( Alexopoulos, AV; Kovac, S; Lineweaver, T; Loddenkemper, T; Möddel, G; Reinholz, J; Schuele, SU; Syed, T, 2009)
" DSA performed by experienced angiographers is a safe procedure that can provide critical diagnostic information."1.33Safety of cerebral digital subtraction angiography in children: complication rate analysis in 241 consecutive diagnostic angiograms. ( Burger, IM; Gailloud, P; Jordan, LC; Murphy, KJ; Tamargo, RJ, 2006)
"Four patients with cerebral arteriovenous malformations (AVMs) underwent superselective Wada testing with intraarterial amobarbital and lidocaine before embolization."1.32Neurobehavioral differences in superselective Wada testing with amobarbital versus lidocaine. ( Fitzsimmons, BF; Lazar, RM; Marshall, RS; Pile-Spellman, J, 2003)
"Transarterial embolization of cerebral arteriovenous malformations (AVMs) has been associated with postprocedural neurologic complications in 7-39% of patients."1.31Tailored cognitive testing with provocative amobarbital injection preceding AVM embolization. ( Gailloud, P; Hart, J; Moo, LR; Murphy, KJ; Tesoro, M, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's7 (43.75)18.2507
2000's7 (43.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kovac, S1
Möddel, G1
Reinholz, J1
Alexopoulos, AV1
Syed, T1
Schuele, SU1
Lineweaver, T1
Loddenkemper, T1
Fitzsimmons, BF1
Marshall, RS2
Pile-Spellman, J2
Lazar, RM3
Bambakidis, NC1
Sunshine, JL1
Faulhaber, PF1
Tarr, RW1
Selman, WR1
Ratcheson, RA1
Burger, IM1
Murphy, KJ2
Jordan, LC1
Tamargo, RJ1
Gailloud, P2
Sass, KJ1
Buchanan, CP1
Westerveld, M1
Spencer, DD1
Chaloupka, JC1
Viñuela, F2
Sakai, N1
Vinters, HV1
Robert, J1
Duckwiler, GR1
Paulsen, RD1
Steinberg, GK1
Norbash, AM1
Marcellus, ML1
Lopez, JR1
Marks, MP1
Duong, HC1
Mohr, JP1
Young, WL1
Solomon, RL1
Perera, GM1
DeLaPaz, RL1
Moo, LR1
Tesoro, M1
Hart, J1
Rosenberg, M1
Sharpe, J1
Hoyt, WF1
Kurthen, M1
Leblanc, R1
Meyer, E1
Bub, D1
Zatorre, RJ1
Evans, AC1
Berthier, ML2
Starkstein, SE2
Lylyk, P2
Leiguarda, R2
Dion, JE1
Duckwiler, G1
Martin, NA1
Fox, A1
Pelz, D1
Drake, CG1
Girvin, JJ1
Debrun, G1
Lylyk, PL1
Casasco, A1
Robinson, RG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Language Functional Reorganization Following Subcortical Cerebral Infarction: A Longitudinal fMRI Study[NCT03668132]80 participants (Actual)Observational2016-01-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for amobarbital and Arteriovenous Malformations, Cerebral

ArticleYear
Functional evaluation of arteriovenous malformations.
    Neurosurgical focus, 2001, Nov-15, Volume: 11, Issue:5

    Topics: Amobarbital; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Humans; Injections, I

2001
Neuropsychological function and brain arteriovenous malformations: redefining eloquence as a risk for treatment.
    Neurosurgical focus, 2001, Nov-15, Volume: 11, Issue:5

    Topics: Amobarbital; Brain Mapping; Cerebral Arteries; Cerebral Hemorrhage; Cognition Disorders; Combined Mo

2001
[The intra-carotid amobarbital test--indications--procedure--results].
    Der Nervenarzt, 1992, Volume: 63, Issue:12

    Topics: Amobarbital; Brain Neoplasms; Carotid Artery, Internal; Dominance, Cerebral; Epilepsy; Humans; Injec

1992

Trials

1 trial available for amobarbital and Arteriovenous Malformations, Cerebral

ArticleYear
Interhemispheric transfer of language in patients with left frontal cerebral arteriovenous malformation.
    Neuropsychologia, 2000, Volume: 38, Issue:10

    Topics: Adult; Amobarbital; Anesthetics, Local; Aphasia, Wernicke; Cerebral Angiography; Cognition; Echo-Pla

2000

Other Studies

12 other studies available for amobarbital and Arteriovenous Malformations, Cerebral

ArticleYear
Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:1

    Topics: Adult; Amobarbital; Brain Neoplasms; Carotid Arteries; Cerebral Angiography; Cerebral Cortex; Epilep

2009
Neurobehavioral differences in superselective Wada testing with amobarbital versus lidocaine.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:7

    Topics: Adult; Amobarbital; Anesthetics, Local; Embolization, Therapeutic; Female; Humans; Hypnotics and Sed

2003
Safety of cerebral digital subtraction angiography in children: complication rate analysis in 241 consecutive diagnostic angiograms.
    Stroke, 2006, Volume: 37, Issue:10

    Topics: Adolescent; Amobarbital; Angiography, Digital Subtraction; Catheterization; Central Nervous System V

2006
Cerebral dominance for speech and handwriting of patients with cortical vascular malformations.
    Journal of clinical and experimental neuropsychology, 1994, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Amobarbital; Brain Damage, Chronic; Brain Mapping; Brain Neoplasms; Diagnostic Im

1994
Potential toxic effects of superselective injection of amobarbital sodium on microvasculature: a study in an animal model.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:8

    Topics: Amobarbital; Animals; Capillaries; Catheterization, Peripheral; Cerebral Angiography; Cerebral Arter

1994
Embolization of rolandic cortex arteriovenous malformations.
    Neurosurgery, 1999, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Amobarbital; Cerebral Angiography; Child; Embolization, Therapeutic; Evoked

1999
Tailored cognitive testing with provocative amobarbital injection preceding AVM embolization.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:3

    Topics: Adult; Amobarbital; Cognition; Cognition Disorders; Embolization, Therapeutic; Female; Humans; Injec

2002
Absent vestibulo-ocular reflexes and acute supratentorial lesions.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:1

    Topics: Acute Disease; Adult; Amobarbital; Anticonvulsants; Brain Stem; Cerebral Arteries; Child; Cranial Si

1975
Language localization with activation positron emission tomography scanning.
    Neurosurgery, 1992, Volume: 31, Issue:2

    Topics: Adult; Amobarbital; Brain Mapping; Dominance, Cerebral; Female; Humans; Intracranial Arteriovenous M

1992
Differential recovery of languages in a bilingual patient: a case study using selective amytal test.
    Brain and language, 1990, Volume: 38, Issue:3

    Topics: Adult; Amobarbital; Angiography, Digital Subtraction; Aphasia; Cerebral Angiography; Dominance, Cere

1990
Combined endovascular embolization and surgery in the management of cerebral arteriovenous malformations: experience with 101 cases.
    Journal of neurosurgery, 1991, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Aged; Amobarbital; Cerebral Hemorrhage; Child; Combined Modality Therapy; Emboliz

1991
Emotional behavior after a Wada test in a patient with secondary mania.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Fall, Volume: 1, Issue:4

    Topics: Adult; Amobarbital; Bipolar Disorder; Dominance, Cerebral; Embolization, Therapeutic; Emotions; Huma

1989