Page last updated: 2024-10-22

amobarbital and Anxiety

amobarbital has been researched along with Anxiety in 53 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."7.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"A double-blind crossover trial comparing lorazepam at two dosage levels with amylobarbitone supported previous reports of the effective anxiolytic action of the drug."6.64A comparison of high- and low-dose lorazepam with amylobarbitone in patients with anxiety states. ( McClelland, HA; Newell, DJ; Schapira, K, 1977)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."3.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
" Twenty-four anxious inpatients were treated with diazepam, amylobarbitone sodium and placebo in flexible dosage for 1 week."2.65A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients. ( Lader, M; Tansella, CZ; Tansella, M, 1979)
"A double-blind crossover trial comparing lorazepam at two dosage levels with amylobarbitone supported previous reports of the effective anxiolytic action of the drug."2.64A comparison of high- and low-dose lorazepam with amylobarbitone in patients with anxiety states. ( McClelland, HA; Newell, DJ; Schapira, K, 1977)
"Twenty-four anxious inpatients were treated with diazepam, amylobarbitone and placebo, each given in flexible dosage for one week, according to a fully-balanced design."2.64Plasma concentrations of diazepam, noradiazepam and amylobarbitone after short-term treatment of anxious patients. ( Ferrario, L; Lader, M; Preziati, L; Tansella, M; Tognoni, G; Zimmermann Tansella, C, 1978)
"A controlled double-blind trial of amitriptyline at two dosage levels (75 and 150 mg/day), amylobarbitone (150 mg/day), and an inert substance for a period of four weeks was conducted on four matched groups of women attending their general practitioners and suffering from a depressive illness."2.64Controlled trial of amitriptyline in general practice. ( Blashki, TG; Davies, B; Mowbray, R, 1971)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199053 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hain, JD2
Smith, BM2
Stevenson, I2
SUSSELMAN, S1
FELDMAN, F1
BARRERA, SE1
GRAHN, HV1
CALDWELL, WG1
NOWERS, W1
COPPEN, AJ1
MEZEY, AG1
KAWI, AA1
JENNER, FA1
KERRY, BJ1
PARKIN, D1
SKURATOVA, SA1
FEIGLEY, DM1
PERRIS, C1
BRATTEMO, CE1
LANCE, JW1
CURRAN, DA1
HERRON, JT1
WESTWOOD, AP1
TIMOFEEVA, AN1
LIPSKAIA, LA1
ROBIN, AA3
ENOCH, MD1
REYNOLDS, E1
JOYCE, CR1
SWIFT, JL1
TOOLEY, PH1
WEATHERALL, M1
WING, L2
LADER, MH5
STRANK, RA1
YOUINGS, MD1
HINTON, JM2
CLINE, WB1
Edmonds, C1
Schapira, K1
McClelland, HA1
Newell, DJ1
Tansella, M2
Zimmermann Tansella, C1
Ferrario, L1
Preziati, L1
Tognoni, G1
Lader, M2
Tansella, CZ1
Julien, I1
Timsit-Berthier, M1
Mizuki, Y2
Suetsugi, M1
Imai, T1
Kai, S1
Kajimura, N1
Yamada, M2
Quintero, S1
Henney, S1
Lawson, P1
Mellanby, J1
Gray, JA3
Hamasaki, J1
Hirano, H1
Miyoshi, A1
Inanaga, K1
Buckman, J1
Bond, AJ2
James, DC2
Turner, P1
Granville-Grossman, KL1
Stevenson, HG1
Perkins, R1
Hinton, J1
Kraft, T2
Hackett, TP1
Cassem, NH1
Wheatley, D1
Blashki, TG1
Mowbray, R1
Davies, B1
Kasich, AM1
McDowall, A1
Owen, S1
Peck, RE1
Meares, R1
Johnson, FG1
Beecher, HK1
Black, AA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors[NCT05364801]500 participants (Anticipated)Observational2022-05-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amobarbital and Anxiety

ArticleYear
Physiological measures in psychiatry.
    The Scientific basis of medicine annual reviews, 1971

    Topics: Adaptation, Psychological; Amobarbital; Animals; Anxiety; Arousal; Blood Pressure; Depression; Elect

1971

Trials

15 trials available for amobarbital and Anxiety

ArticleYear
Effectiveness and processes of interviewing with drugs.
    Journal of psychiatric research, 1966, Volume: 4, Issue:2

    Topics: Amobarbital; Anxiety; Attention; Drug-Related Side Effects and Adverse Reactions; Female; Humans; In

1966
A comparison of high- and low-dose lorazepam with amylobarbitone in patients with anxiety states.
    The American journal of psychiatry, 1977, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Amobarbital; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Drug E

1977
Plasma concentrations of diazepam, noradiazepam and amylobarbitone after short-term treatment of anxious patients.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1978, Volume: 11, Issue:2

    Topics: Adult; Amobarbital; Anxiety; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged;

1978
A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:6

    Topics: Adult; Amobarbital; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans

1979
A physiological marker for assessing anxiety level in humans: frontal midline theta activity.
    The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:4

    Topics: Adult; Amobarbital; Anxiety; Arousal; Diazepam; Electroencephalography; Frontal Lobe; Humans; Male;

1989
Effects of centrally acting drugs on the frontal midline theta activity in man.
    The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:4

    Topics: Adult; Amobarbital; Anxiety; Arousal; Diazepam; Electroencephalography; Frontal Lobe; Humans; Male;

1986
Controlled interviews using drugs. II. Comparisons between restricted and freer conditions.
    Archives of general psychiatry, 1973, Volume: 29, Issue:5

    Topics: Adult; Amobarbital; Anger; Anxiety; Attitude of Health Personnel; Attitude to Health; Clinical Trial

1973
Sedative effects on physiological and psychological measures in anxious patients.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Amobarbital; Anti-Anxiety Agents; Anxiety; Auditory Perception; Chlordiazepoxide; Chronic Disease; C

1974
Clinical comparison of anxiolytic drug therapy.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Amobarbital; Anti-Anxiety Agents; Anxiety; Barbiturates; Ca

1974
Reduction of anxiety in the coronary-care unit. A controlled double-blind comparison of chlordiazepoxide and amobarbital.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:10

    Topics: Adult; Aged; Amobarbital; Analgesics; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Coronary

1972
Controlled trial of amitriptyline in general practice.
    British medical journal, 1971, Jan-16, Volume: 1, Issue:5741

    Topics: Adolescent; Adult; Amitriptyline; Amobarbital; Anxiety; Clinical Trials as Topic; Depression; Family

1971
A double-blind study of heteronium bromide and amobarbital in the management of gastrointestinal conditions associated with anxiety.
    Current therapeutic research, clinical and experimental, 1968, Volume: 10, Issue:10

    Topics: Adult; Aged; Amobarbital; Anxiety; Clinical Trials as Topic; Colonic Diseases, Functional; Duodenal

1968
Comparative bioassay of chlordiazepoxide and amylobarbitone sodium therapies in patients with anxiety states using physiological and clinical measures.
    Journal of neurology, neurosurgery, and psychiatry, 1965, Volume: 28, Issue:5

    Topics: Amobarbital; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Electrophysiology; Female; Galvani

1965
Chlordiazepoxide in anxiety states.
    The Practitioner, 1965, Volume: 195, Issue:169

    Topics: Adolescent; Adult; Aged; Amobarbital; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio

1965
A controlled comparison of diazepam and amylobarbitone in anxiety states.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:487

    Topics: Amobarbital; Anxiety; Clinical Trials as Topic; Diazepam; Humans

1966

Other Studies

37 other studies available for amobarbital and Anxiety

ArticleYear
Intravenous injection of sodium amytal as a test for latent anxiety.
    Archives of neurology and psychiatry, 1946, Volume: 56, Issue:5

    Topics: Amobarbital; Anesthesia; Anesthesiology; Anxiety; Anxiety Disorders; Barbital; Injections, Intraveno

1946
Use of a d-amphetamine-amobarbital combination as an adjunct to the treatment of carcinoma.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:9

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Dext

1954
Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital.
    California medicine, 1958, Volume: 88, Issue:5

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Apathy; Depression; Depressive Disorder; Dextroamph

1958
The influence of sodium amytal on the respiratory abnormalities of anxious psychiatric patients.
    Journal of psychosomatic research, 1960, Volume: 5

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Humans; Mental Disorders; Patients; Psychotherapy; Respirat

1960
Effects of sodium amytal and ethyl alcohol on some psychological and psychomotor functions.
    Journal of neuropsychiatry, 1961, Volume: 2

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Ethanol; Humans; Mental Disorders; Psychological Tests

1961
A controlled comparison of methaminodiazepoxide (chlordiazepoxide, "Librium") and amylobarbitone in the treatment of anxiety in neurotic patients.
    The Journal of mental science, 1961, Volume: 107

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Chlordiazepoxide; Humans; Neurotic Disorders; Tranquilizing

1961
[The formation of spinal cord dominants during changes of the functional state of the nervous centers by the action of narcotic substances].
    Biulleten' eksperimental'noi biologii i meditsiny, 1960, Volume: 49

    Topics: Amobarbital; Anxiety; Chloral Hydrate; Narcotics; Spinal Cord

1960
Office care of mild emotional distress.
    Diseases of the nervous system, 1962, Volume: 23

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Atropa belladonna; Depression; D

1962
THE SEDATION THRESHOLD AS A METHOD OF EVALUATING ANTI-DEPRESSIVE TREATMENTS; A PRELIMINARY REPORT.
    Acta psychiatrica Scandinavica, 1963, Volume: 39

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Electroencephalography; Hu

1963
TREATMENT OF CHRONIC TENSION HEADACHE.
    Lancet (London, England), 1964, Jun-06, Volume: 1, Issue:7345

    Topics: Amitriptyline; Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diaze

1964
ADVANTAGES OF SUSTAINED-RELEASE AMYLOBARBITONE IN THE TREATMENT OF ANXIETY.
    The Medical journal of Australia, 1964, Aug-01, Volume: 2

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Blood; Delayed-Action Preparations; Drug Therapy; Humans

1964
[BARBAMYL-TOFRANIL TEST IN THE EVALUATION OF THE DEPRESSIVE STATE].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1963, Volume: 63

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Bipolar Disorder; Delirium; Delusions; Depression; Depressi

1963
A VALIDATION STUDY OF NEALBARBITONE.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Barbiturates; Biomedical Research; Drug Therapy; Humans

1964
PSYCHOLOGICAL AND CLINICAL INVESTIGATION OF THE TREATMENT OF ANXIOUS OUT-PATIENT WITH THREE BARBITURATES AND PLACEBO.
    The British journal of psychiatry : the journal of mental science, 1965, Volume: 111

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Barbiturates; Biomedical Research; Drug Therapy; Humans; Me

1965
PHYSIOLOGICAL AND CLINICAL EFFECTS OF AMYLOBARBITONE SODIUM THERAPY IN PATIENTS WITH ANXIETY STATES.
    Journal of neurology, neurosurgery, and psychiatry, 1965, Volume: 28

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Drug Therapy; Galvanic Skin Response;

1965
ANXIETY NEUROSIS COMPLICATED BY ADDICTION TO SODIUM AMYTAL.
    Nursing times, 1965, Jun-11, Volume: 61

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Neurotic Disorders; Substance-Related Disorders; Toxicology

1965
NARCOANALYSIS OF THE SUBCONSCIOUS MIND.
    British journal of medical hypnotism : official organ of the British Society of Medical Hypnotists, 1965, Volume: 16

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Humans; Narcotherapy; Neurotic Disorders; Thiopental; Uncon

1965
A comparison of perphenazine, ('fentazin') sodium amylobarbitone and a placebo in anxious and depressed out-patients.
    The Journal of mental science, 1959, Volume: 105

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Outpatients; Perph

1959
Pecazine ("pacatal") compared with amylobarbitone sodium in anxiety states.
    The Journal of mental science, 1959, Volume: 105

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Phenothiazines; Sodium

1959
Sodium amytal in treatment of anxiety states; a preliminary report.
    Diseases of the nervous system, 1952, Volume: 13, Issue:2

    Topics: Amobarbital; Anxiety; Anxiety Disorders; Barbiturates; Neurotic Disorders

1952
Severe somnambulism: a case study.
    Journal of clinical psychology, 1967, Volume: 23, Issue:2

    Topics: Adult; Amobarbital; Anxiety; Behavior Therapy; Dreams; Electroconvulsive Therapy; Enuresis; Female;

1967
[Problems of methodology when studying the relationship between EEG and behaviour: use of the technique of sedation threshold to sodium amytal (author's transl)].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1978, Volume: 8, Issue:3

    Topics: Adult; Amobarbital; Anxiety; Behavior; Cerebral Cortex; Electroencephalography; Female; Humans; Male

1978
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
    Psychopharmacology, 1985, Volume: 85, Issue:2

    Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepox

1985
The neuropsychology of anxiety.
    Issues in mental health nursing, 1985, Volume: 7, Issue:1-4

    Topics: Amobarbital; Anti-Anxiety Agents; Anxiety; Conditioning, Classical; Hippocampus; Humans; Neuropsycho

1985
Effect of adrenergic receptor blockade of the tachycardia of thyrotoxicosis and anxiety state.
    Lancet (London, England), 1965, Dec-25, Volume: 2, Issue:7426

    Topics: Adult; Amobarbital; Anxiety; Female; Heart Rate; Humans; Hyperthyroidism; Injections, Intravenous; I

1965
Back injury and depression--a medico-legal problem.
    The Medical journal of Australia, 1970, Jun-27, Volume: 1, Issue:26

    Topics: Adjustment Disorders; Adult; Amobarbital; Anxiety; Cervical Vertebrae; Electroconvulsive Therapy; Hu

1970
Sedative or tranquillizer? A comparison of the hypnotic effects of chlordiazepoxide and amylobarbitone sodium.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:0

    Topics: Adult; Amobarbital; Analysis of Variance; Anxiety; Chlordiazepoxide; Dose-Response Relationship, Dru

1974
Successful treatment of "drinamyl" addicts and associated personality changes.
    Canadian Psychiatric Association journal, 1970, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anxiety; Behavior Therapy; Hospitalization; Humans; Male; MMPI; Pers

1970
Benzodiazepines and anxiety states.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:3

    Topics: Amobarbital; Anxiety; Benzazepines; Chlordiazepoxide; Humans; Imipramine; Phenobarbital

1973
The application of thymometry to the measurement of anxiety.
    International journal of neuropsychiatry, 1966, Volume: 2, Issue:4

    Topics: Amobarbital; Anxiety; Audiometry; Carbon Dioxide; Emotions; Humans; Nystagmus, Pathologic; Pain; Pro

1966
Treatment of drinamyl addiction: two case studies.
    The Journal of nervous and mental disease, 1970, Volume: 150, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anxiety; Behavior Therapy; Humans; Hypnosis; Male; Physician-Patient

1970
The place of barbiturates in psychiatric treatment.
    The Medical journal of Australia, 1970, Jun-13, Volume: 1, Issue:24

    Topics: Abreaction; Affective Symptoms; Amobarbital; Anxiety; Barbiturates; Chlordiazepoxide; Humans; Hypnot

1970
The psychophysiological basis of introversion-extraversion.
    Behaviour research and therapy, 1970, Volume: 8, Issue:3

    Topics: Adult; Amobarbital; Animals; Anxiety; Arousal; Avoidance Learning; Cerebral Cortex; Cerebral Ventric

1970
A comparison of short-term treatment effects of intravenous sodium amytal-methedrine and LSD in the alcoholic.
    Canadian Psychiatric Association journal, 1970, Volume: 15, Issue:5

    Topics: Affect; Alcoholism; Amobarbital; Anxiety; Canada; Depression; Hallucinations; Humans; Injections, In

1970
Anxiety and pain.
    JAMA, 1969, Aug-18, Volume: 209, Issue:7

    Topics: Amobarbital; Anxiety; Fear; Humans; Hysteria; Male; Military Medicine; Morphine; Pain; Time Factors;

1969
Physiological measurements in psychiatry.
    Proceedings of the Royal Society of Medicine, 1966, Volume: 59, Issue:10

    Topics: Amobarbital; Anxiety; Emotions; Humans; Mental Disorders; Psychophysiology

1966
Factors predisposing to a placebo response in new out-patients with anxiety states.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:487

    Topics: Adolescent; Adult; Amobarbital; Anxiety; Attitude; Female; Humans; Male; Middle Aged; Personality; P

1966