ammonium hydroxide has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 14 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperammonemia has been reported following asparaginase administration, consistent with the mechanisms of asparaginase, which catabolizes asparagine to aspartic acid and ammonia, and secondarily converts glutamine to glutamate and ammonia." | 4.31 | Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia. ( Altintas, B; Eldem, I; Langley, R; Lee, A; Nguyen, H; Shinawi, M; Willis, D, 2023) |
| "Patients with acute lymphoblastic leukemia (ALL), who develop antiasparaginase antibodies without clinical allergic reactions ("silent inactivation") during L: -asparaginase (L: -Asp) treatment, have poor outcomes." | 2.74 | The ex vivo production of ammonia predicts L-asparaginase biological activity in children with acute lymphoblastic leukemia. ( Hasegawa, D; Hirabayashi, S; Hosoya, R; Inoue, T; Kizu, J; Machida, R; Manabe, A; Matsumoto, H; Miyake, K; Ogawa, C; Ohara, A; Watanabe, S; Yoshida, K, 2009) |
| "A group of 87 patients with acute lymphoblastic leukemia treated in the Department of Pediatric Oncology and Hematology in Krakow was enrolled to the study." | 1.40 | Clinical utility of ammonia concentration as a diagnostic test in monitoring of the treatment with L-asparaginase in children with acute lymphoblastic leukemia. ( Balwierz, W; Czogała, M; Rogatko, I; Sztefko, K, 2014) |
| "Of the 23 patients studied, 3 developed hepatic encephalopathy." | 1.39 | [Analysis of L-asparaginase induced elevation of blood ammonia and hepatic encephalopathy]. ( Cen, XN; Li, Y; Liang, ZY; Ren, HY; Yin, Y, 2013) |
| "The standard treatment protocol for acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) in childhood includes intravenous therapy with asparaginase (Asp), which may cause hyperammonemia." | 1.37 | Transient hyperammonemia due to L-asparaginase therapy in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma. ( Beblo, S; Bierbach, U; Jörck, C; Kiess, W; Mütze, U; Weigel, JF, 2011) |
| "One day after admission, she developed hepatic encephalopathy with ammonia concentrations in plasma >100 micromol/l." | 1.35 | Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia. ( Dada, R; Galm, O; Gassler, N; Jost, E; Osieka, R; Wilop, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Buddington, RK | 1 |
| Buddington, KK | 1 |
| Howard, SC | 1 |
| Lee, A | 1 |
| Eldem, I | 1 |
| Altintas, B | 1 |
| Nguyen, H | 1 |
| Willis, D | 1 |
| Langley, R | 1 |
| Shinawi, M | 1 |
| Gallin, M | 1 |
| Damaj, L | 1 |
| Gandemer, V | 1 |
| Bendavid, C | 1 |
| Moreau, C | 1 |
| Muneer, F | 1 |
| Siddique, MH | 1 |
| Azeem, F | 1 |
| Rasul, I | 1 |
| Muzammil, S | 1 |
| Zubair, M | 1 |
| Afzal, M | 1 |
| Nadeem, H | 1 |
| Santos, AC | 1 |
| Land, MGP | 1 |
| Lima, EC | 1 |
| Li, Y | 1 |
| Ren, HY | 1 |
| Cen, XN | 1 |
| Yin, Y | 1 |
| Liang, ZY | 1 |
| Czogała, M | 1 |
| Balwierz, W | 1 |
| Sztefko, K | 1 |
| Rogatko, I | 1 |
| Tong, WH | 1 |
| Pieters, R | 1 |
| van der Sluis, IM | 1 |
| Watanabe, S | 1 |
| Miyake, K | 1 |
| Ogawa, C | 1 |
| Matsumoto, H | 1 |
| Yoshida, K | 1 |
| Hirabayashi, S | 1 |
| Hasegawa, D | 1 |
| Inoue, T | 1 |
| Kizu, J | 1 |
| Machida, R | 1 |
| Ohara, A | 1 |
| Hosoya, R | 1 |
| Manabe, A | 1 |
| Dada, R | 1 |
| Wilop, S | 1 |
| Jost, E | 1 |
| Galm, O | 1 |
| Gassler, N | 1 |
| Osieka, R | 1 |
| Jörck, C | 1 |
| Kiess, W | 1 |
| Weigel, JF | 1 |
| Mütze, U | 1 |
| Bierbach, U | 1 |
| Beblo, S | 1 |
| Sudour, H | 1 |
| Schmitt, C | 1 |
| Contet, A | 1 |
| Chastagner, P | 1 |
| Feillet, F | 1 |
| Steiner, M | 1 |
| Attarbaschi, A | 1 |
| Kastner, U | 1 |
| Dworzak, M | 1 |
| Haas, OA | 1 |
| Gadner, H | 1 |
| Mann, G | 1 |
| Xu, SR | 1 |
| Yao, EG | 1 |
| Dong, ZR | 1 |
| Liu, RS | 1 |
| Pan, L | 1 |
| Lin, FR | 1 |
| Zhang, RX | 1 |
| Liu, MC | 1 |
| Ma, BB | 1 |
| Yin, JQ | 1 |
2 reviews available for ammonium hydroxide and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
[Molecular basis of hyperammonemia secondary to asparaginase: from therapeutic efficacity to toxicity].
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Humans; Hyperammonemia; Precursor Cell Lymphoblastic L | 2023 |
Microbial L-asparaginase: purification, characterization and applications.
Topics: Ammonia; Asparaginase; Asparagine; Aspartic Acid; Bacteria; Fungi; Hodgkin Disease; Humans; Phylogen | 2020 |
2 trials available for ammonium hydroxide and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
The ex vivo production of ammonia predicts L-asparaginase biological activity in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Biomarkers; Child; Child, Preschool; Drug Monitoring; | 2009 |
Distinct fluctuations of ammonia levels during asparaginase therapy for childhood acute leukemia.
Topics: Adolescent; Ammonia; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Drug Monitoring; | 2007 |
10 other studies available for ammonium hydroxide and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Multiple Asparaginase Infusions Cause Increasingly Severe Acute Hyperammonemia.
Topics: Ammonia; Animals; Antineoplastic Agents; Asparaginase; Hyperammonemia; Precursor Cell Lymphoblastic | 2022 |
Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Glutamine; Humans; Hyperammonemia; Phenylbutyra | 2023 |
Ammonia level as a proxy of asparaginase inactivation in children: A strategy for classification of infusion reactions.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Drug Hypersensitivity; Humans; Hyperammonemia; | 2022 |
[Analysis of L-asparaginase induced elevation of blood ammonia and hepatic encephalopathy].
Topics: Adolescent; Adult; Aged; Ammonia; Asparaginase; Female; Hepatic Encephalopathy; Humans; Male; Middle | 2013 |
Clinical utility of ammonia concentration as a diagnostic test in monitoring of the treatment with L-asparaginase in children with acute lymphoblastic leukemia.
Topics: Adolescent; Ammonia; Asparaginase; Child; Child, Preschool; Diagnostic Tests, Routine; Female; Human | 2014 |
Ammonia Levels Should Not Be Used as a Surrogate Marker of Levels of Asparaginase Activity in Acute Lymphoblastic Leukemia Patients.
Topics: Ammonia; Asparaginase; Biomarkers; Child; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pr | 2016 |
Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia.
Topics: Adult; Alanine Transaminase; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Aspartate Amin | 2009 |
Transient hyperammonemia due to L-asparaginase therapy in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Topics: Adolescent; Ammonia; Antineoplastic Agents; Asparaginase; Child; Female; Humans; Hyperammonemia; Lym | 2011 |
Acute metabolic encephalopathy in two patients treated with asparaginase and ondasetron.
Topics: Adolescent; Ammonia; Asparaginase; Brain Diseases, Metabolic; Humans; Male; Precursor Cell Lymphobla | 2011 |
Plasma ammonia in patients with acute leukemia.
Topics: Adolescent; Adult; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia | 1992 |