ammonium hydroxide has been researched along with Nephrocalcinosis in 8 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
Nephrocalcinosis: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FELTS, JH | 1 |
| HEADLEY, RN | 1 |
| WHITLEY, JE | 1 |
| YOUNT, EH | 1 |
| Wrong, OM | 1 |
| Feest, TG | 1 |
| Rodríguez-Soriano, J | 1 |
| Vallo, A | 1 |
| Miller, SG | 1 |
| Schwartz, GJ | 1 |
| Gennari, FJ | 1 |
| Cohen, JJ | 1 |
| Moncrieff, MW | 1 |
| Chance, GW | 1 |
| Buckalew, VM | 1 |
| McCurdy, DK | 1 |
| Ludwig, GD | 1 |
| Chaykin, LB | 1 |
| Elkinton, JR | 1 |
| Györy, AZ | 1 |
| Edwards, KD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevention of Post-Cardiac Surgery Vitamin D Deficiency in Children With Congenital Heart Disease: A Pilot Dose Evaluation Randomized Controlled Trial[NCT01838447] | Phase 2 | 46 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Blood 25OHD will be measured to determine vitamin D deficiency, with a concentration below 50 nmol/L used to define deficiency. A PICU admission blood sample could not be obtained for one patient in the Usual Care Group and one patient in the High Dose Group, thus the total number analyzed differs from the full sample size. (NCT01838447)
Timeframe: 1 day (On admission to the pediatric intensive care unit (PICU) following CHD surgery)
| Intervention | nmol/L (Mean) |
|---|---|
| Usual Care Group | 34.8 |
| High Dose Group | 52.0 |
Hypercalcemia will be defined as an ionized calcium level above 1.40 mmol/L; or above 1.45 mmol/L for children under 8 weeks. Hypercalcemia will be evaluated in blood collected immediately before CHD surgery and throughout the post-operative course (measurements are standard of care). (NCT01838447)
Timeframe: Immediately before surgery, on admission to the PICU following CHD surgery, and on post-operative days 1,3,5 & 10
| Intervention | No. participants with hypercalcemia (Number) |
|---|---|
| Usual Care Group | 0 |
| High Dose Group | 0 |
Primarily, post-operative catecholamine requirements during the PICU admission will be evaluated as a dichotomous variable (yes/no). If a difference is noted in the primary analysis, inotrope requirements will be determined using the inotrope score, evaluated as the maximum score and in a time to event approach (off all inotropes, score of zero) (NCT01838447)
Timeframe: At any point between PICU admission and discharge, an average length of 5-7 days and not longer than 60 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Usual Care Group | 15 |
| High Dose Group | 11 |
Hypercalciuria will be identified using calcium:creatinine ratios defined using age-specific norms and thresholds. (NCT01838447)
Timeframe: Immediately before surgery, on admission to the PICU following CHD surgery, and on the first post-operative day
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Enrolment | Intra-operative | Post-Operative Day 1 | |
| High Dose Group | 0 | 4 | 1 |
| Usual Care Group | 1 | 3 | 2 |
1 review available for ammonium hydroxide and Nephrocalcinosis
| Article | Year |
|---|---|
Renal tubular acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Ammonia; Bicarbonates; Biological Transport; Carbon | 1978 |
7 other studies available for ammonium hydroxide and Nephrocalcinosis
| Article | Year |
|---|---|
MEDULLARY SPONGE KIDNEYS. CLINICAL APPRAISAL.
Topics: Ammonia; Animals; Edetic Acid; Geriatrics; Humans; Kidney; Kidney Calculi; Kidney Diseases; Kidney D | 1964 |
The natural history of distal renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Age Factors; Ammonia; Bone Diseases, Metabolic; Carbon D | 1980 |
Pathophysiology of the renal acidification defect present in the syndrome of familial hypomagnesaemia-hypercalciuria.
Topics: Acidosis, Renal Tubular; Ammonia; Calcium; Child; Child, Preschool; Female; Glomerular Filtration Ra | 1994 |
Hyperammonaemia with distal renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Ammonia; Failure to Thrive; Female; Follow-Up Studies; Humans; Infant; Neph | 1997 |
Nephrotoxic effect of vitamin D therapy in vitamin D refractory rickets.
Topics: Ammonia; Biopsy; Calcium; Child; Child, Preschool; Female; Humans; Infant; Kidney; Kidney Diseases; | 1969 |
Incomplete renal tubular acidosis. Physiologic studies in three patients with a defect in lowering urine pH.
Topics: Acidosis, Renal Tubular; Adult; Ammonia; Ammonium Chloride; Bicarbonates; Blood Urea Nitrogen; Calci | 1968 |
Renal tubular acidosis. A family with an autosomal dominant genetic defect in renal hydrogen ion transport, with proximal tubular and collecting duct dysfunction and increased metabolism of citrate and ammonia.
Topics: Acidosis, Renal Tubular; Adult; Aged; Ammonia; Chromosome Aberrations; Chromosome Disorders; Citrate | 1968 |