ammonium hydroxide has been researched along with Metabolic Diseases in 60 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An effective and rapid treatment of hyperammonemia is crucial to prevent irreversible neurological damage and it depends on the understanding of the pathophysiology of the diseases, as well as of the available therapeutic approaches." | 2.82 | Hyperammonemia in Inherited Metabolic Diseases. ( Deon, M; Lopes, FF; Ribas, GS; Vargas, CR, 2022) |
| "Reye Syndrome is an acute encephalopathy with increased liver enzymes and blood ammonia, without jaundice." | 1.72 | What are the clues for an inherited metabolic disorder in Reye syndrome? A single Centre study of 58 children. ( Angoulvant, F; Arnoux, JB; Brassier, A; de Lonlay, P; Debray, D; Girard, M; Goetz, V; Heilbronner, C; Lacaille, F; Oualha, M; Pelosi, M; Renolleau, S; Salvador, E; Schiff, M; Yang, DD, 2022) |
| "Inborn errors of metabolism are an individually rare but collectively significant cause of mortality and morbidity in the neonatal period." | 1.72 | Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre. ( Boyle, MA; Brady, JJ; Dunne, E; Howard, C; Kelleher, G; Khuffash, AE; Knerr, I; Murphy, CA; O'Reilly, D; Suttie, T, 2022) |
| " In both group A and group B patients, plasma ammonia levels were correlated with the valproic acid dosage (r = 0." | 1.30 | Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs. ( Chiarelli, F; Greco, R; Morgese, G; Verrotti, A, 1999) |
| "Women with heterozygous ornithine transcarbamylase deficiency may have no symptoms or have episodic, symptomatic hyperammonemia, which can be fatal." | 1.28 | Heterozygote ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate therapy. ( Callahan, K; Evans, B; Honeycutt, D; Rutledge, L, 1992) |
| "The condition resembles hepatic encephalopathy but can occur without obvious liver disease." | 1.27 | Hyperammonemic encephalopathy related to ureterosigmoidostomy. ( Edwards, RH, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (65.00) | 18.7374 |
| 1990's | 10 (16.67) | 18.2507 |
| 2000's | 2 (3.33) | 29.6817 |
| 2010's | 4 (6.67) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ribas, GS | 1 |
| Lopes, FF | 1 |
| Deon, M | 1 |
| Vargas, CR | 1 |
| Eminoğlu, FT | 1 |
| Öncül, Ü | 1 |
| Kahveci, F | 1 |
| Okulu, E | 1 |
| Kraja, E | 1 |
| Köse, E | 1 |
| Kendirli, T | 1 |
| Goetz, V | 1 |
| Yang, DD | 1 |
| Lacaille, F | 1 |
| Pelosi, M | 1 |
| Angoulvant, F | 1 |
| Brassier, A | 1 |
| Arnoux, JB | 1 |
| Schiff, M | 1 |
| Heilbronner, C | 1 |
| Salvador, E | 1 |
| Debray, D | 1 |
| Oualha, M | 1 |
| Renolleau, S | 1 |
| Girard, M | 1 |
| de Lonlay, P | 1 |
| Dunne, E | 1 |
| O'Reilly, D | 1 |
| Murphy, CA | 1 |
| Howard, C | 1 |
| Kelleher, G | 1 |
| Suttie, T | 1 |
| Boyle, MA | 1 |
| Brady, JJ | 1 |
| Knerr, I | 1 |
| Khuffash, AE | 1 |
| Gramignoli, R | 2 |
| Ranade, AR | 2 |
| Venkataramanan, R | 2 |
| Strom, SC | 2 |
| Metz, MP | 1 |
| Markus, C | 1 |
| Metz, M | 1 |
| He, Y | 1 |
| Hakvoort, TB | 1 |
| Vermeulen, JL | 1 |
| Labruyère, WT | 1 |
| De Waart, DR | 1 |
| Van Der Hel, WS | 1 |
| Ruijter, JM | 1 |
| Uylings, HB | 1 |
| Lamers, WH | 1 |
| Broomfield, A | 1 |
| Grunewald, S | 1 |
| SUMMERSKILL, WH | 2 |
| WOLFE, SJ | 1 |
| DAVIDSON, CS | 1 |
| DAWSON, AM | 1 |
| DE GROOTE, J | 1 |
| ROSENTHAL, WA | 1 |
| SHERLOCK, S | 1 |
| CAESAR, J | 1 |
| RICHTERICH, R | 1 |
| DONATH, A | 1 |
| SPAHR, A | 1 |
| ROSSI, E | 1 |
| LEDERER, J | 1 |
| BARNESS, LA | 1 |
| WETTON, R | 1 |
| RITCHIE, HD | 1 |
| Robertson, DS | 1 |
| Tuchman, M | 2 |
| Caldovic, L | 1 |
| Daikhin, Y | 1 |
| Horyn, O | 1 |
| Nissim, I | 2 |
| Korson, M | 1 |
| Burton, B | 1 |
| Yudkoff, M | 1 |
| Nicolaides, K | 1 |
| Rodeck, CH | 1 |
| Edwards, RH | 1 |
| Seashore, JH | 1 |
| Lattanzi, A | 1 |
| Huizenga, JR | 1 |
| Tangerman, A | 1 |
| Gips, CH | 1 |
| Kulick, SK | 1 |
| Kramer, DA | 1 |
| Sekas, G | 1 |
| Paul, HS | 1 |
| Lichtenstein, GR | 1 |
| Kaiser, LR | 1 |
| Palevsky, HI | 1 |
| Kotloff, RM | 1 |
| O'Brien, CB | 1 |
| Furth, EE | 1 |
| Raps, EC | 1 |
| Berry, GT | 1 |
| Bruno, C | 1 |
| Bado, M | 1 |
| Minetti, C | 1 |
| Cordone, G | 1 |
| Verrotti, A | 1 |
| Greco, R | 1 |
| Morgese, G | 1 |
| Chiarelli, F | 1 |
| Weinman, EJ | 1 |
| Busch, H | 1 |
| Eisenhart-Rothe, BV | 1 |
| Steigmann, F | 1 |
| Attili, AF | 1 |
| Cascino, A | 1 |
| Rossi Fanelli, F | 1 |
| Capocaccia, L | 1 |
| Devivo, DC | 1 |
| Keating, JP | 1 |
| Riva, E | 1 |
| Borzani, M | 1 |
| Motta, G | 1 |
| Giovannini, M | 1 |
| Honeycutt, D | 1 |
| Callahan, K | 1 |
| Rutledge, L | 1 |
| Evans, B | 1 |
| Van Geet, C | 1 |
| Vandenbossche, L | 1 |
| Eggermont, E | 1 |
| Devlieger, H | 1 |
| Vermylen, J | 1 |
| Jaeken, J | 1 |
| Tse, N | 1 |
| Cederbaum, S | 1 |
| Glaspy, JA | 1 |
| Weigle, CG | 1 |
| Koehler, RC | 1 |
| Brusilow, SW | 1 |
| Traystman, RJ | 1 |
| Morgan, HB | 1 |
| Swaiman, KF | 1 |
| Johnson, BD | 1 |
| Heller, SL | 1 |
| Kaiser, KK | 1 |
| Planer, GJ | 1 |
| Hagberg, JM | 1 |
| Brooke, MH | 1 |
| Lockwood, AH | 1 |
| Merin, S | 1 |
| Crawford, JS | 1 |
| Wada, Y | 1 |
| Tada, K | 1 |
| Takada, G | 1 |
| Omura, K | 1 |
| Yoshida, T | 1 |
| Imler, M | 1 |
| Ruscher, H | 1 |
| Peter, B | 1 |
| Kurtz, D | 1 |
| Stahl, J | 1 |
| Transbol, I | 1 |
| Frydendal, N | 1 |
| Huguet, C | 1 |
| Bloch, P | 1 |
| Morisot, P | 1 |
| Levy, E | 1 |
| Loygue, J | 1 |
| Gouin, B | 1 |
| Gosset, F | 1 |
| Hardouin, JP | 1 |
| Walker, FA | 1 |
| Juggi, JS | 1 |
| Prior, RL | 1 |
| Zimber, A | 1 |
| Visek, WJ | 1 |
| Tarnawski, A | 1 |
| Batko, B | 1 |
| Pierach, CA | 1 |
| Cairns, LC | 1 |
| Hankiewicz, J | 1 |
| Liappis, N | 1 |
| Brodehl, J | 1 |
| Jäkel, A | 1 |
| Kolpakov, VG | 1 |
| Ziegler, K | 1 |
| Bossi, M | 1 |
| Cantono, GM | 1 |
| Palminiello, L | 1 |
| Nordmann, R | 1 |
| Thorsell, F | 1 |
| Feinberg, JH | 1 |
| Aldrete, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate[NCT01341379] | Phase 2 | 0 participants (Actual) | Interventional | 2010-12-31 | Withdrawn (stopped due to Lack of funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for ammonium hydroxide and Metabolic Diseases
| Article | Year |
|---|---|
Hyperammonemia in Inherited Metabolic Diseases.
Topics: Ammonia; Fatty Acids; Humans; Hyperammonemia; Infant, Newborn; Metabolic Diseases; Urea | 2022 |
[Pathogenesis and therapy of nitrogen catabolism disorders: hyperazotemia versus hyperammonemia versus hyperuricemia].
Topics: Ammonia; Humans; Metabolic Diseases; Nitrogen; Purines; Pyrimidines; Uric Acid | 1981 |
Determination of ammonia in biological fluids.
Topics: Ammonia; Blood Preservation; Blood Specimen Collection; Body Fluids; Chromatography, High Pressure L | 1994 |
[Physiopathology of ammonia].
Topics: Ammonia; Body Fluids; Brain; Hepatic Encephalopathy; Humans; Metabolic Diseases | 1976 |
Reye's syndrome.
Topics: Ammonia; Blood Coagulation Disorders; Brain; Brain Diseases; Child; Clinical Enzyme Tests; Electroen | 1976 |
[Some problems of hyperammonemia].
Topics: Ammonia; Arginase; Enzymes; Humans; Ligases; Liver Cirrhosis; Lyases; Metabolic Diseases; Metabolism | 1969 |
1 trial available for ammonium hydroxide and Metabolic Diseases
| Article | Year |
|---|---|
N-carbamylglutamate markedly enhances ureagenesis in N-acetylglutamate deficiency and propionic acidemia as measured by isotopic incorporation and blood biomarkers.
Topics: Acetyl Coenzyme A; Adult; Amino Acids; Ammonia; Biomarkers; Carbon Dioxide; Carbon Isotopes; Child; | 2008 |
53 other studies available for ammonium hydroxide and Metabolic Diseases
| Article | Year |
|---|---|
Characteristics of continuous venovenous hemodiafiltration in the acute treatment of inherited metabolic disorders.
Topics: Aged; Ammonia; Child; Continuous Renal Replacement Therapy; Hemodiafiltration; Humans; Hypotension; | 2022 |
What are the clues for an inherited metabolic disorder in Reye syndrome? A single Centre study of 58 children.
Topics: Acidosis; Ammonia; Child; Child, Preschool; Humans; Metabolic Diseases; Retrospective Studies; Reye | 2022 |
Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre.
Topics: Ammonia; Blood Glucose; Humans; Infant; Infant, Newborn; Lactates; Metabolic Diseases; Metabolism, I | 2022 |
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes.
Topics: Ammonia; Cytokines; Hepatocytes; Humans; Liver; Liver Diseases; Metabolic Diseases | 2022 |
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes.
Topics: Ammonia; Cytokines; Hepatocytes; Humans; Liver; Liver Diseases; Metabolic Diseases | 2022 |
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes.
Topics: Ammonia; Cytokines; Hepatocytes; Humans; Liver; Liver Diseases; Metabolic Diseases | 2022 |
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes.
Topics: Ammonia; Cytokines; Hepatocytes; Humans; Liver; Liver Diseases; Metabolic Diseases | 2022 |
Ammonia, a troublesome analyte.
Topics: Ammonia; Biomarkers; Early Diagnosis; Humans; Metabolic Diseases; Reference Values | 2014 |
Comparison of plasma ammonia results from seven different automated platforms in use throughout Central Australia.
Topics: Ammonia; Australia; Automation, Laboratory; Hematology; Humans; Metabolic Diseases; Reference Values | 2017 |
Glutamine synthetase deficiency in murine astrocytes results in neonatal death.
Topics: Adenylate Kinase; Amino Acids; Ammonia; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; | 2010 |
How to use serum ammonia.
Topics: Ammonia; Child; Child, Preschool; Education, Medical, Continuing; Humans; Hyperammonemia; Infant; Me | 2012 |
The metabolism of ammonia and alpha-keto-acids in liver disease and hepatic coma.
Topics: Ammonia; Coma; Hepatic Encephalopathy; Humans; Keto Acids; Ketones; Liver Diseases; Metabolic Diseas | 1957 |
AMMONIA metabolism and hepatic coma.
Topics: Ammonia; Coma; Hepatic Encephalopathy; Humans; Liver Diseases; Metabolic Diseases | 1957 |
The effects of diamox ammonia metabolism in liver disease.
Topics: Acetazolamide; Ammonia; Humans; Liver Diseases; Metabolic Diseases | 1957 |
Levels of glutamine and ammonia and the pH of cerebrospinal fluid and plasma in patients with liver disease.
Topics: Ammonia; Blood; Blood Chemical Analysis; Cerebrospinal Fluid; Glutamine; Humans; Hydrogen-Ion Concen | 1962 |
CONGENITAL LYSINE INTOLERANCE WITH PERIODIC AMMONIA INTOXICATION.
Topics: Ammonia; Biopsy; Blood Chemical Analysis; Dietary Proteins; Genetics, Medical; Humans; Hyperlysinemi | 1964 |
[DISEASES CAUSED BY METABOLIC DISORDER OF THE KREBS-HENSELEIT CYCLE].
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Blood Chemical Analysis; Child; Dietary Pro | 1964 |
ACIDOSIS AND ALKALOSIS.
Topics: Acidosis; Alkalosis; Ammonia; Blood Proteins; Carbon Dioxide; Child; Hemoglobins; Humans; Metabolic | 1964 |
Ammonia metabolism in liver failure and some methods of reducing high blood levels.
Topics: Ammonia; Humans; Liver Diseases; Liver Failure; Metabolic Diseases | 1962 |
The chemical reactions in the human stomach and the relationship to metabolic disorders.
Topics: Adult; Ammonia; Antacids; Asthma; Bicarbonates; Calcium Chloride; Calcium Phosphates; Chlorides; Dig | 2005 |
Prenatal diagnosis. Fetoscopy.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Female; Fetal Blood; Fetal Diseases; Fetoscopy; Genet | 1984 |
Hyperammonemic encephalopathy related to ureterosigmoidostomy.
Topics: Adult; Ammonia; Brain Diseases; Brain Edema; Female; Humans; Metabolic Diseases; Tomography, X-Ray C | 1984 |
Metabolic complications of parenteral nutrition in infants and children.
Topics: Acid-Base Imbalance; Adolescent; Amino Acids; Ammonia; Avitaminosis; Child; Child, Preschool; Choles | 1980 |
Hyperammonemia secondary to valproic acid as a cause of lethargy in a postictal patient.
Topics: Adult; Ammonia; Epilepsy, Complex Partial; Humans; Male; Metabolic Diseases; Valproic Acid | 1993 |
Hyperammonemia and carnitine deficiency in a patient receiving sulfadiazine and pyrimethamine.
Topics: Adult; Ammonia; Carnitine; Drug Therapy, Combination; Humans; Male; Metabolic Diseases; Pyrimethamin | 1993 |
Fatal hyperammonemia following orthotopic lung transplantation.
Topics: Ammonia; Fatal Outcome; Female; Humans; Liver; Lung; Lung Transplantation; Metabolic Diseases; Micro | 1997 |
Forearm semi-ischemic exercise test in pediatric patients.
Topics: Adolescent; Ammonia; Child; Exercise Test; Forearm; Humans; Lactic Acid; Metabolic Diseases; Reperfu | 1998 |
Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs.
Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Carnitine; Child; Child, Preschool; Epilepsy; Female; H | 1999 |
Uric acid and the kidney.
Topics: Acute Kidney Injury; Ammonia; Animals; Glomerular Filtration Rate; Glutamine; Gout; Humans; Hydrogen | 1976 |
[Old and new dangers of blood transfusion (author's transl)].
Topics: Ammonia; Blood; Blood Coagulation Factors; Blood Group Antigens; Blood Preservation; Cytomegalovirus | 1976 |
Preventing portal systemic encephalopathy in the patient with cirrhosis.
Topics: Ammonia; Anemia; Dietary Carbohydrates; Dietary Proteins; Gastrointestinal Hemorrhage; Hepatic Encep | 1979 |
[Changes of serum ammonium in various pediatric diseases in relation to the treatment with anti-ammonemic drugs].
Topics: Ammonia; Arginine; Carboxylic Acids; Child, Preschool; Citrates; Female; Humans; Infant; Male; Metab | 1976 |
Heterozygote ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate therapy.
Topics: Adult; Ammonia; Female; Heterozygote; Humans; Metabolic Diseases; Ornithine Carbamoyltransferase Def | 1992 |
Possible platelet contribution to pathogenesis of transient neonatal hyperammonaemia syndrome.
Topics: Ammonia; beta-Thromboglobulin; Catheterization; Evaluation Studies as Topic; Female; Humans; Infant, | 1991 |
Hyperammonemia following allogeneic bone marrow transplantation.
Topics: Ammonia; Bone Marrow Transplantation; Female; Humans; Metabolic Diseases; Middle Aged; Renal Dialysi | 1991 |
Arterial pH modulation of regional cerebral blood flow during hyperammonemia in dogs.
Topics: Ammonia; Animals; Blood Gas Analysis; Brain; Cerebral Arteries; Dogs; Female; Glutamates; Glutamic A | 1990 |
Diagnosis of argininosuccinic aciduria after valproic acid-induced hyperammonemia.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Argininosuccinic Acid; F | 1987 |
McArdle's disease with myoadenylate deaminase deficiency: observations in a combined enzyme deficiency.
Topics: Adult; Ammonia; AMP Deaminase; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Hu | 1987 |
Metabolic encephalopathies: opportunities and challenges.
Topics: Ammonia; Animals; Brain; Brain Diseases; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Me | 1987 |
The etiology of congenital cataracts. A survey of 386 cases.
Topics: Ammonia; Birth Weight; Cataract; Central Nervous System Diseases; Congenital Abnormalities; Down Syn | 1971 |
Hyperglycinemia associated with hyperammonemia: in vitro glycine cleavage in liver.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Biopsy; Glycine; Humans; In Vitro Techniques; Infant; | 1972 |
[Action of arginine in a recurrent hepatic coma complicating a feminizing tumor of the adrenal cortex with hepatic metastases].
Topics: Adolescent; Adrenal Gland Neoplasms; Ammonia; Arginine; Estrogens; Feminization; Hepatic Encephalopa | 1973 |
Endocrine and metabolic aspects of urology. Aetiology of stone formation in 145 renal stone patients.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Aged; Ammonia; Calcium; Calcium Metabolism Disorders; Ch | 1973 |
[Major hepatectomy in man. Metabolic consequences].
Topics: Adolescent; Adult; Ammonia; Bilirubin; Blood Coagulation Disorders; Blood Coagulation Tests; Blood P | 1972 |
[Horton's disease. Neuropsychological disorders and hyperammoniemia (apropos of a case)].
Topics: Ammonia; Brain Diseases; Cortisone; Depression; Electroencephalography; Giant Cell Arteritis; Humans | 1972 |
Lactulose enemas.
Topics: Ammonia; Child; Dehydration; Disaccharides; Enema; Fructose; Humans; Lactulose; Metabolic Diseases | 1973 |
Extracorporeal cation-exchange circuits in the treatment of hyperammonaemia of hepatic failure.
Topics: Adult; Ammonia; Calcium; Child; Female; Hepatic Encephalopathy; Humans; Ion Exchange Resins; Magnesi | 1973 |
Magnesium metabolism in the hyperammonemic rat.
Topics: Acids; Ammonia; Animals; Bone and Bones; Brain; Colon; Kidney; Liver; Magnesium; Magnesium Deficienc | 1974 |
[Metabolic hazards of blood transfusions].
Topics: Acidosis; Ammonia; Blood Preservation; Citrates; Humans; Hydrogen-Ion Concentration; Hyperkalemia; M | 1972 |
[Clinical use of ammonia determination in the blood and urine].
Topics: Age Factors; Ammonia; Humans; Metabolic Diseases; Methods | 1972 |
[Ammonium concentration in the venous blood of infants and children].
Topics: Adolescent; Age Factors; Ammonia; Analysis of Variance; Chemistry, Clinical; Child; Child, Preschool | 1971 |
[On the probable pathogenetic mechanisms of epilepsy].
Topics: 5-Hydroxytryptophan; Alanine; Ammonia; Animals; Asparagine; Carboxy-Lyases; Epilepsy; Glutamates; Li | 1967 |
[Hyperammonemia and its treatment].
Topics: Ammonia; Colectomy; Diet Therapy; Humans; Metabolic Diseases | 1969 |
[Action of an association of amino acids of the Krebs-Henseleit cycle on the serum levels of nitrogen and ammonia in humans].
Topics: Adult; Aged; Amino Acids; Ammonia; Brain Injuries; Coma; Coronary Disease; Female; Heart Diseases; H | 1970 |
[Amnoniacal detoxication and cerearal metabolism].
Topics: Acidosis, Respiratory; Ammonia; Brain; Brain Diseases; Coma; Hepatic Encephalopathy; Humans; Liver D | 1967 |
Effects of urease inhibition in hyperammonemia: clinical and experimental studies with acetohydroxamic acid.
Topics: Aged; Ammonia; Animals; Bilirubin; Budd-Chiari Syndrome; Dogs; Fasting; Female; Hepatic Encephalopat | 1968 |