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ammonium hydroxide and Inflammation

ammonium hydroxide has been researched along with Inflammation in 95 studies

azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" A study was carried out to investigate the response of genes involved in inflammation, antioxidation, polarization and apoptosis in head kidney macrophages to acute ammonia toxicity, and the alleviation effect of curcumin."8.02Effect of acute ammonia toxicity on inflammation, oxidative stress and apoptosis in head kidney macrophage of Pelteobagrus fulvidraco and the alleviation of curcumin. ( Dong, R; Gan, L; He, K; Jiang, H; Luo, X; Qin, C; Shao, J; Wang, C; Wen, M, 2021)
"Myocardial ischemia is characterized by the liberation of adenosine and by complement-mediated inflammation."7.67The erythrocyte as instigator of inflammation. Generation of amidated C3 by erythrocyte adenosine deaminase. ( Hostetter, MK; Johnson, GM, 1989)
" Inflammation and manganese accumulation are also thought to be important in pathogenesis."4.95Hepatic Encephalopathy. ( Gow, AG, 2017)
" Impaired renal proteolytic activity caused by such factors as high protein intake, metabolic acidosis, angiotensin II and transforming growth factor-beta 1 in vivo and in vitro may result in decreased protein degradation and subsequent induction of cellular hypertrophy, even in the absence of increased protein synthesis."4.79Impaired proteolytic activity as a potential cause of progressive renal disease. ( Heidland, A; Ling, H; Paczek, L; Vamvakas, S, 1996)
" Based on CMR, segments were classified as remote (n = 469), healed (inflammation at baseline but no late gadolinium enhancement [LGE] at follow-up, n = 118), and scarred (LGE at follow-up, n = 72)."4.31Long-term impact of myocardial inflammation on quantitative myocardial perfusion-a descriptive PET/MR myocarditis study. ( Bakula, A; Benz, DC; Buechel, RR; Ciancone, D; Giannopoulos, AA; Gräni, C; Heidecker, B; Kaufmann, PA; Manka, R; Patriki, D; Pazhenkottil, AP; Schmidt, GA; von Felten, E; Wahl, A, 2023)
" A study was carried out to investigate the response of genes involved in inflammation, antioxidation, polarization and apoptosis in head kidney macrophages to acute ammonia toxicity, and the alleviation effect of curcumin."4.02Effect of acute ammonia toxicity on inflammation, oxidative stress and apoptosis in head kidney macrophage of Pelteobagrus fulvidraco and the alleviation of curcumin. ( Dong, R; Gan, L; He, K; Jiang, H; Luo, X; Qin, C; Shao, J; Wang, C; Wen, M, 2021)
" We have conducted studies to determine whether the protection afforded by the administration of sodium bicarbonate is sustained and prevents development of uremia during chronic administration and whether the effects of the administration of ammonium chloride and sodium bicarbonate are also observed in a different model of polycystic kidney disease, the CD1-pcy/pcy mouse."3.71Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease. ( Branden, MG; Cowley, BD; Gattone, VH; Torres, VE; Yoshida, I, 2001)
"Myocardial ischemia is characterized by the liberation of adenosine and by complement-mediated inflammation."3.67The erythrocyte as instigator of inflammation. Generation of amidated C3 by erythrocyte adenosine deaminase. ( Hostetter, MK; Johnson, GM, 1989)
"About 20% of patients with acute liver failure (ALF) die from increased intracranial pressure (ICP) while awaiting transplantation."2.71Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension. ( Deutz, NE; Hayes, PC; Jalan, R; Lee, A; Olde Damink, SW, 2004)
"Fifty pediatric patients with congenital heart defects took part in this study."2.70Ultrafiltration of the priming blood before cardiopulmonary bypass attenuates inflammatory response and improves postoperative clinical course in pediatric patients. ( Fujinaga, K; Kanemitsu, S; Mitani, Y; Onoda, K; Sawamura, Y; Shimamoto, A; Shimpo, H; Takao, M; Yada, I, 2001)
"Neuropathology of hepatic encephalopathy (HE) in cirrhosis is primarily astroglial in nature characterized by Alzheimer type 2 astrocytosis together with activation of microglia indicative of neuroinflammation."2.61Hepatic Encephalopathy in Cirrhosis: Pathology and Pathophysiology. ( Butterworth, RF, 2019)
"Recently, inflammation has also been identified as a contributor to HE."2.50Pathophysiology, diagnosis, and management of hepatic encephalopathy. ( Lu, L; Patel, A; Sheasgreen, C, 2014)
"Infection and inflammation have been associated with the development of delirium for many centuries and there is a rapidly growing evidence base supporting the role of inflammation in exacerbating the neurological manifestations of both acute and chronic liver failure."2.49Systemic inflammation and ammonia in hepatic encephalopathy. ( Ryan, JM; Shawcross, DL; Tranah, TH; Vijay, GK, 2013)
"The face of hepatic encephalopathy (HE) is changing."2.46Changing face of hepatic encephalopathy: role of inflammation and oxidative stress. ( Hughes, RD; Seyan, AS; Shawcross, DL, 2010)
"Brain edema with intracranial hypertension is a major complication in patients with acute liver failure."2.43Mild hypothermia for acute liver failure: a review of mechanisms of action. ( Blei, AT; Vaquero, J, 2005)
"Inflammation is likely an important target of BBD to treat HE."1.56BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats. ( An, YT; Bahaji Azami, NL; Lu, BJ; Lu, L; Sun, MY; Wang, HJ; Wang, Z; Wu, C; Xie, D; Ye, G, 2020)
"Inflammation is an essential biological process for maintaining homeostasis in the body."1.56The inflammatory injury of heart caused by ammonia is realized by oxidative stress and abnormal energy metabolism activating inflammatory pathway. ( Han, Q; Hu, G; Wang, H; Xing, H; Xu, Y; Zhang, Y, 2020)
"Although lupus nephritis (LN) is mostly characterized by glomerular involvement, tubular injury is indispensable in its pathogenesis and progression."1.56Value of monitoring urine ammonia at time of biopsy in patients with lupus nephritis. ( Duan, S; Li, Q; Liu, S; Wan, H; Wu, L; Xing, C; Yuan, Y; Zhang, B; Zhang, C; Zhu, H, 2020)
"It is associated with a wide range of sleep disorders that are generally attributed to nasal congestion and presence of inflammatory mediators like cytokines and interleukins."1.46Rhinitis and sleep disorders: The trigeminocardiac reflex link? ( Bindu, B; Chowdhury, T; Schaller, B; Singh, GP, 2017)
"Silver nanoparticles have been used for different purposes in dentistry, including endodontic treatments."1.43In Vitro and In Vivo Toxicity Evaluation of Colloidal Silver Nanoparticles Used in Endodontic Treatments. ( Barbosa, DB; Bernabé, DG; Camargo, ER; Gomes-Filho, JE; Gorup, LF; Monteiro, DR; Oliveira, SH; Takamiya, AS, 2016)
"We analyzed the presence of mild cognitive impairment (CI) by using the PHES battery of psychometric tests and measured the levels of ammonia and of the inflammatory cytokines IL-6 and IL-18 in blood of patients with different types of liver or dermatological diseases resulting in different grades of hyperammonemia and/or inflammation."1.38Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. ( Cassinello, N; Civera, M; Felipo, V; Garcia-Torres, ML; Jordá, E; Martinez-Valls, J; Molina, I; Montesinos, E; Montoliu, C; Olmo, JA; Ortega, J; Serra, MA; Urios, A; Wassel, A, 2012)
"Systemic inflammation may affect brain function by reducing the BCAA/AAA ratio, thereby changing the cerebral net exchange of LNAAs."1.36Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans. ( Bailey, DM; Berg, RM; Larsen, FS; Lundby, C; Møller, K; Pedersen, BK; Taudorf, S, 2010)
"Laryngopharyngeal or gastroesophageal reflux is associated with laryngeal airway hyperreactivity (LAH), but neither the cause-effect relationship nor the underlying mechanism has been elucidated."1.33Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats. ( Chang, SY; Ho, CY; Kou, YR; Tsai, TL, 2006)
"Hyperammonemia was induced by oral administration of an amino-acid (aa) solution mimicking hemoglobin composition."1.32Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis. ( Davies, NA; Jalan, R; Shawcross, DL; Williams, R, 2004)
" Dose-response curves were constructed for the inflammatory reactions induced in nasal cavities, the smooth muscle hyperresponsiveness in the trachea, the permeability of alveolo-capillary barrier, the pulmonary vasomotricity, the cough reflex and the systemic effects."1.30[Effect of ammonia on the pig respiratory system. Study of the dose-response relation]. ( Gustin, P, 1999)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19906 (6.32)18.7374
1990's7 (7.37)18.2507
2000's19 (20.00)29.6817
2010's34 (35.79)24.3611
2020's29 (30.53)2.80

Authors

AuthorsStudies
Zhou, Y4
Zhang, M3
Zhao, X3
Feng, J3
Feng, R1
Qin, X1
Li, Q2
Olugbenga Adeniran, S1
Huang, F1
Li, Y9
Zhao, Q1
Zheng, P1
Wang, J9
Wang, Y11
Liu, H6
Bao, J3
Elbakry, MMM1
Mansour, SZ1
Helal, H1
Ahmed, ESA1
Xing, H5
Zhuo, H3
Liu, J8
Zhang, C6
Ma, J1
Qi, Q1
Xu, M1
Xu, R1
Zhong, L1
Liu, S3
Zuo, F1
Geng, Y1
Ouyang, P1
Chen, D7
Yang, S3
Zheng, W2
Xiong, Y1
Cai, W1
Huang, X3
Wang, K2
Shen, D1
Dai, P1
Li, C3
Ripoll, C1
Greinert, R1
Reuken, P1
Reichert, MC1
Weber, SN1
Hupfer, Y1
Staltner, R1
Meier Clinien, M1
Lammert, F1
Bruns, T1
Zipprich, A1
Buechel, RR1
Ciancone, D1
Bakula, A1
von Felten, E1
Schmidt, GA1
Patriki, D1
Gräni, C1
Wahl, A1
Manka, R1
Heidecker, B1
Benz, DC1
Giannopoulos, AA1
Pazhenkottil, AP1
Kaufmann, PA1
Long, X2
He, K3
Li, M1
Wang, Z4
Wang, C4
Dong, X3
Shao, J3
Gan, L2
Hu, X1
Jiang, H3
Wei, S1
Liu, T3
Zhao, Y4
Xiao, Y1
Zhou, D3
Zheng, J2
Ding, Z1
Xu, Q1
Limbu, SM1
Kong, Y1
Rafaqat, S2
Sattar, A1
Khalid, A1
Shi, Z1
Xi, L1
Benko, A1
Medina-Cruz, D1
Wilk, S1
Ziąbka, M1
Zagrajczuk, B1
Menaszek, E1
Barczyk-Woźnicka, O1
Guisbiers, G1
Webster, TJ1
Yan, Z2
Wan, J1
Yao, B1
Lu, Y2
Guo, Z2
Percival, E1
Collison, AM1
da Silva Sena, CR1
De Queiroz Andrade, E1
De Gouveia Belinelo, P1
Gomes, GMC1
Oldmeadow, C1
Murphy, VE1
Gibson, PG1
Karmaus, W1
Mattes, J1
Wang, S2
Li, X6
Wang, W4
Zhang, H3
Xu, S2
Zheng, DW1
Li, CX2
Zou, MZ1
Yu, WY1
Liu, MD1
Peng, SY1
Zhong, ZL1
Zhang, XZ1
Lu, L2
Wu, C1
Lu, BJ1
Xie, D2
Bahaji Azami, NL1
An, YT1
Wang, HJ1
Ye, G1
Sun, MY1
Jaffe, A1
Lim, JK1
Jakab, SS1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Zhou, L1
Huang, L2
Hu, K1
Wang, H5
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K2
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X5
Yao, LP1
Qin, QP1
Wang, ZY1
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z2
Zhu, J3
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z3
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Sun, M1
Xu, G1
Zhang, X7
Xu, N1
Wang, R1
He, H1
Yang, M2
Yang, Q1
Duan, S2
Yu, Y2
Han, J2
Chen, L3
Yang, X1
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H4
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S1
Zhai, X1
Gilson, E1
Ye, J1
Yan, R1
Zhang, Y9
Hu, Z1
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L4
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X1
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M2
An, Z1
Jiang, J2
Li, J8
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Liu, Y7
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A2
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L2
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X2
Wu, Y2
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Fan, Y2
Sun, YB1
Wang, AL1
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J3
Chu, S1
Pan, Q1
Li, D2
Zheng, S2
Ma, L1
Wang, L3
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X2
Dai, T1
Yang, Y3
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
Du, Q1
Hao, P1
Cao, X1
Zhao, S1
Luo, XM1
Feng, JX1
Gonzalez-Cotto, M1
Guo, L1
Karwan, M1
Sen, SK1
Barb, J1
Collado, CJ1
Elloumi, F1
Palmieri, EM1
Boelte, K1
Kolodgie, FD1
Finn, AV1
Biesecker, LG1
McVicar, DW1
Qu, F1
Deng, Z1
Xie, Y2
Tang, J3
Chen, Z2
Luo, W1
Xiong, D1
Zhao, D1
Fang, J1
Zhou, Z1
Niu, PP1
Song, B1
Xu, YM1
Zhang, Z2
Qiu, N1
Yin, J1
Zhang, J4
Guo, W1
Liu, M2
Luo, K1
He, Z2
Zheng, G1
Xu, F1
Sun, W1
Yin, F1
van Hest, JCM1
Du, L2
Shi, X1
Kang, S2
Duan, W1
Zhang, S2
Qi, N1
Shen, G1
Ren, H1
Shang, Q1
Zhao, W2
Yang, Z2
Jiang, X2
Alame, M1
Cornillot, E1
Cacheux, V1
Tosato, G1
Four, M1
De Oliveira, L1
Gofflot, S1
Delvenne, P1
Turtoi, E1
Cabello-Aguilar, S1
Nishiyama, M1
Turtoi, A1
Costes-Martineau, V1
Colinge, J1
Guo, Q1
Quan, M1
Dong, J1
Bai, J1
Han, R1
Cai, Y1
Lv, YQ1
Chen, Q1
Lyu, HD1
Deng, L1
Xiao, X1
De Langhe, S1
Billadeau, DD1
Lou, Z1
Zhang, JS1
Xue, Z1
Shen, XD1
Gao, F1
Busuttil, RW1
Kupiec-Weglinski, JW1
Ji, H1
Otano, I1
Alvarez, M1
Minute, L1
Ochoa, MC1
Migueliz, I1
Molina, C1
Azpilikueta, A1
de Andrea, CE1
Etxeberria, I1
Sanmamed, MF1
Teijeira, Á1
Berraondo, P1
Melero, I1
Zhong, Z1
Xie, X1
Yu, Q1
Zhou, C1
Liu, C2
Liu, W1
Chen, W1
Yin, Y1
Li, CW1
Hsu, JL1
Zhou, Q1
Hu, B1
Fu, P1
Atyah, M1
Ma, Q2
Xu, Y2
Dong, Q1
Hung, MC1
Ren, N1
Huang, P1
Liao, R1
Chen, X5
Cao, Q1
Yuan, X1
Nie, W1
Yang, J2
Shao, B1
Ma, X1
Bi, Z1
Liang, X1
Tie, Y1
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Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Prospective, Randomized Controlled Study to Explore the Efficacy and Safety of Fecal Microbiota Transplantation With Different Bacterial Doses in the Treatment of Recurrent Hepatic Encephalopathy[NCT05669651]100 participants (Anticipated)Interventional2022-12-01Active, not recruiting
Effects of Synbiotics Supplementation on the Concentration of the Uremic Toxin Indoxyl Sulfate, Symptoms of Constipation, and Constipation-related Quality of Life in End-stage Renal Disease Patients Undergoing Hemodialysis[NCT04527640]60 participants (Anticipated)Interventional2020-09-15Not yet recruiting
Prebiotic Therapy to Improve Outcomes of Renal Transplant[NCT04428190]Early Phase 160 participants (Anticipated)Interventional2022-02-23Recruiting
Plasma Free Amino Acids in Patients With Hepatic Encephalopathy and Its Impact on Disease Outcomes.[NCT03306498]100 participants (Anticipated)Observational2017-12-15Not yet recruiting
A Phase 2a Study to Evaluate the Safety and Tolerability of OCR-002 (Ornithine Phenylacetate) in the Treatment of Patients With Acute Liver Failure/Severe Acute Liver Injury[NCT01548690]Phase 247 participants (Actual)Interventional2012-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Ammonia

To evaluate the effect of OCR-002 on ammonia levels in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: Baseline and 72 Hours

InterventionPercent Change (Mean)
Maximum Dose Level 3.33 g/24h41.2
Maximum Dose Level 6.65 g/24h16.6
Maximum Dose Level 10 g/24h41.8
Maximum Dose Level 20g/24h38.4

Measurement of OCR-002 Plasma Concentration

To evaluate the steady state pharmacokinetic and pharmacodynamic profile of OCR-002 in patients with impaired and intact renal function using urinary phenylacetylglutamine (PAGN) as a surrogate marker (NCT01548690)
Timeframe: 24 Hours after last infusion

Interventionmicrograms per millileter (Mean)
Maximum Dose Level 3.33 g/24h65.6
Maximum Dose Level 6.65 g/24h32.2
Maximum Dose Level 10 g/24h33.4
Maximum Dose Level 20g/24h104.9

Neurological Function Measured by the Orientation Log (O-log)

The orientation log focuses on orientation to place, time, and circumstance. There are 10 items on the orientation log, which are scored 0-3. A spontaneous correct response is awarded 3 points. A spontaneous response that is lacking or incorrect, but a correct response is provided following a logical cue is awarded 2 points. A score of 1 is given if spontaneous and cued responses are lacking or incorrect, but a correct response is provided in a recognition format. A score of 0 is given if the spontaneous, cued, or recognition format does not generate a correct answer. Scores from the 10 items are summed and the final score ranges from 0 to 30. (NCT01548690)
Timeframe: 30 Days

Interventionunits on a scale (Mean)
Maximum Dose Level 3.33 g/24h23.8
Maximum Dose Level 6.65 g/24h24.0
Maximum Dose Level 10 g/24h24.0
Maximum Dose Level 20g/24h24.0

Neurological Function Measured by the West Haven Criteria (WHC) for Hepatic Encephalopathy

The West Haven Criteria (WHC) for Hepatic Encephalopathy measures the severity of encephalopathy and patient's level of consciousness. The scale ranges from 0 to 4; a minimum score of 0 represents a better outcome, and a maximum total score of 4 represents a worse outcome. A score of 0 corresponds to normal consciousness and behavior and normal neurological examination. A score of 1 corresponds to mild lack of awareness, shortened attention span, and impaired addition or subtraction; mild asterixis or tremor. A score of 2 corresponds to lethargy, disorientated or inappropriate behavior, obvious asterixis; slurred speech. A score of 3 corresponds to somnolent but arousable, gross disorientation or bizarre behavior, muscle rigidity and clonus; hyperreflexia. A score of 4 corresponds to coma and decerebrate posturing. (NCT01548690)
Timeframe: 120 hours from start of infusion

Interventionunits on a scale (Mean)
Maximum Dose Level 3.33 g/24h2.4
Maximum Dose Level 6.65 g/24h3.2
Maximum Dose Level 10 g/24h1.6
Maximum Dose Level 20g/24h1.8

Number of Participants That do Not Tolerate the Administered Dose and Had Grade 3 or 4 Treatment Emergent Adverse Events as a Measure of Safety and Tolerability

To evaluate the safety and tolerability of OCR-002 in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: 30 Days

InterventionParticipants (Count of Participants)
Maximum Dose Level 3.33 g/24h0
Maximum Dose Level 6.65 g/24h0
Maximum Dose Level 10 g/24h0
Maximum Dose Level 20g/24h0

Reviews

23 reviews available for ammonium hydroxide and Inflammation

ArticleYear
Particulate matter in poultry house on poultry respiratory disease: a systematic review.
    Poultry science, 2023, Volume: 102, Issue:4

    Topics: Air Pollutants; Ammonia; Animals; Chickens; Inflammation; Particulate Matter; Poultry; Respiratory T

2023
Role of liver parameters in diabetes mellitus - a narrative review.
    Endocrine regulations, 2023, Jan-01, Volume: 57, Issue:1

    Topics: Albumins; alpha-Fetoproteins; Ammonia; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2;

2023
Pathophysiology of Hepatic Encephalopathy.
    Clinics in liver disease, 2020, Volume: 24, Issue:2

    Topics: Ammonia; Animals; Astrocytes; Diabetes Complications; gamma-Aminobutyric Acid; Gastrointestinal Micr

2020
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Recent advances in understanding and managing hepatic encephalopathy in chronic liver disease.
    F1000Research, 2020, Volume: 9

    Topics: Ammonia; Hepatic Encephalopathy; Humans; Inflammation; Quality of Life

2020
Hepatic Encephalopathy in Cirrhosis: Pathology and Pathophysiology.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Ammonia; Basal Ganglia; Cerebellum; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Inflamm

2019
Gut microbiota and hepatic encephalopathy.
    Metabolic brain disease, 2013, Volume: 28, Issue:2

    Topics: Ammonia; Animals; Hepatic Encephalopathy; Humans; Inflammation; Intestines; Microbiota; Probiotics

2013
Inflammation and hepatic encephalopathy.
    Archives of biochemistry and biophysics, 2013, Aug-15, Volume: 536, Issue:2

    Topics: Ammonia; Animals; Brain; Endotoxemia; Gastrointestinal Tract; Hepatic Encephalopathy; Humans; Inflam

2013
Brain edema in acute liver failure: mechanisms and concepts.
    Metabolic brain disease, 2014, Volume: 29, Issue:4

    Topics: Acute Disease; Ammonia; Animals; Astrocytes; Body Water; Brain Edema; Cell Size; Confounding Factors

2014
Ammonia and amino acid profiles in liver cirrhosis: effects of variables leading to hepatic encephalopathy.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:1

    Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Brain; Dietary Proteins; Glutamine; Hep

2015
Pathophysiology, diagnosis, and management of hepatic encephalopathy.
    Inflammopharmacology, 2014, Volume: 22, Issue:6

    Topics: Ammonia; Anti-Bacterial Agents; Anti-Inflammatory Agents; Hepatic Encephalopathy; Humans; Inflammati

2014
Clinical science workshop: targeting the gut-liver-brain axis.
    Metabolic brain disease, 2016, Volume: 31, Issue:6

    Topics: Ammonia; Animals; Anti-Inflammatory Agents; Brain; Drug Delivery Systems; Education; Gastrointestina

2016
Hepatic Encephalopathy.
    The Veterinary clinics of North America. Small animal practice, 2017, Volume: 47, Issue:3

    Topics: Ammonia; Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Hepatic Encephalopa

2017
Changing face of hepatic encephalopathy: role of inflammation and oxidative stress.
    World journal of gastroenterology, 2010, Jul-21, Volume: 16, Issue:27

    Topics: Ammonia; Animals; Astrocytes; Brain; Cognition Disorders; Hepatic Encephalopathy; Humans; Immunity,

2010
Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema.
    Metabolic brain disease, 2013, Volume: 28, Issue:2

    Topics: Ammonia; Animals; Blood-Brain Barrier; Brain; Brain Edema; Cytokines; Hepatic Encephalopathy; Humans

2013
Systemic inflammation and ammonia in hepatic encephalopathy.
    Metabolic brain disease, 2013, Volume: 28, Issue:1

    Topics: Ammonia; Hepatic Encephalopathy; Humans; Immunity, Innate; Inflammation; Liver Failure; Systemic Inf

2013
Prevention and treatment of hepatic encephalopathy: focusing on gut microbiota.
    World journal of gastroenterology, 2012, Dec-14, Volume: 18, Issue:46

    Topics: Ammonia; Anti-Bacterial Agents; Clinical Trials as Topic; Gastroenterology; Hepatic Encephalopathy;

2012
Inflammatory interactions in fish exposed to pollutants and parasites: a role for apoptosis and C reactive protein.
    Parasitology, 2003, Volume: 126 Suppl

    Topics: Ammonia; Animals; Apoptosis; Biomarkers; C-Reactive Protein; Cadmium; Carps; Disease Susceptibility;

2003
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects].
    Gastroenterologia y hepatologia, 2004, Volume: 27 Suppl 1

    Topics: Ammonia; Brain; Brain Edema; Dipeptides; Flumazenil; Glutaminase; Glutamine; Hepatic Encephalopathy;

2004
Mild hypothermia for acute liver failure: a review of mechanisms of action.
    Journal of clinical gastroenterology, 2005, Volume: 39, Issue:4 Suppl 2

    Topics: Ammonia; Brain; Brain Edema; Cerebrovascular Circulation; Glucose; Hemodynamics; Humans; Hypothermia

2005
The pathophysiologic basis of hepatic encephalopathy: central role for ammonia and inflammation.
    Cellular and molecular life sciences : CMLS, 2005, Volume: 62, Issue:19-20

    Topics: Ammonia; Astrocytes; Hepatic Encephalopathy; Humans; Inflammation

2005
Impaired proteolytic activity as a potential cause of progressive renal disease.
    Mineral and electrolyte metabolism, 1996, Volume: 22, Issue:1-3

    Topics: Acidosis; Ammonia; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Dietary Proteins; Endop

1996
Glutaminase and the control of airway pH: yet another problem for the asthmatic lung?
    American journal of respiratory and critical care medicine, 2002, Jan-01, Volume: 165, Issue:1

    Topics: Ammonia; Animals; Anti-Inflammatory Agents; Asthma; Breath Tests; Case-Control Studies; Glutaminase;

2002

Trials

5 trials available for ammonium hydroxide and Inflammation

ArticleYear
The association of exhaled nitric oxide with air pollutants in young infants of asthmatic mothers.
    Environmental health : a global access science source, 2023, Dec-05, Volume: 22, Issue:1

    Topics: Air Pollutants; Air Pollution; Ammonia; Asthma; Carbon Monoxide; Female; Humans; Infant; Inflammatio

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Oral glutamine in paediatric oncology patients: a dose finding study.
    European journal of clinical nutrition, 2003, Volume: 57, Issue:1

    Topics: Administration, Oral; Adolescent; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Area Unde

2003
Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension.
    Gastroenterology, 2004, Volume: 127, Issue:5

    Topics: Adult; Ammonia; Biomarkers; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Female; Humans;

2004
Ultrafiltration of the priming blood before cardiopulmonary bypass attenuates inflammatory response and improves postoperative clinical course in pediatric patients.
    Shock (Augusta, Ga.), 2001, Volume: 16 Suppl 1

    Topics: Ammonia; Bradykinin; Cardiopulmonary Bypass; Cytokines; Female; Heart Defects, Congenital; Humans; H

2001

Other Studies

68 other studies available for ammonium hydroxide and Inflammation

ArticleYear
Ammonia exposure induced intestinal inflammation injury mediated by intestinal microbiota in broiler chickens via TLR4/TNF-α signaling pathway.
    Ecotoxicology and environmental safety, 2021, Dec-15, Volume: 226

    Topics: Ammonia; Animals; Chickens; Gastrointestinal Microbiome; Inflammation; NF-kappa B; Signal Transducti

2021
Progesterone regulates inflammation and receptivity of cells via the NF-κB and LIF/STAT3 pathways.
    Theriogenology, 2022, Jul-01, Volume: 186

    Topics: Ammonia; Animals; Cattle; Cattle Diseases; Embryo Implantation; Epidermal Growth Factor; Female; Inf

2022
Selenium Alleviates Ammonia-Induced Splenic Cell Apoptosis and Inflammation by Regulating the Interleukin Family/Death Receptor Axis and Nrf2 Signaling Pathway.
    Biological trace element research, 2023, Volume: 201, Issue:4

    Topics: Ammonia; Animals; Antioxidants; Apoptosis; Chickens; Humans; Inflammation; Interleukins; NF-E2-Relat

2023
Nattokinase attenuates bisphenol A or gamma irradiation-mediated hepatic and neural toxicity by activation of Nrf2 and suppression of inflammatory mediators in rats.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:49

    Topics: Ammonia; Animals; Benzhydryl Compounds; Gamma Rays; Heme Oxygenase-1; Inflammation; Inflammation Med

2022
Selenium Mitigates Ammonia-Induced Neurotoxicity by Suppressing Apoptosis, Immune Imbalance, and Gut Microbiota-Driven Metabolic Disturbance in Fattening Pigs.
    Biological trace element research, 2023, Volume: 201, Issue:7

    Topics: Ammonia; Animals; Antioxidants; Apoptosis; Female; Gastrointestinal Microbiome; Inflammation; Phosph

2023
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress.
    Fish & shellfish immunology, 2022, Volume: 131

    Topics: Ammonia; Animals; Antioxidants; Inflammation; Interleukin-3; NF-kappa B; Penaeidae; Phylogeny; RNA,

2022
Effects of ammonia exposure on anxiety behavior, oxidative stress and inflammation in guppy (Poecilia reticulate).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2023, Volume: 265

    Topics: Ammonia; Animals; Antioxidants; Anxiety; Inflammation; Interleukin-6; Oxidative Stress; Poecilia; RN

2023
The IL17 signaling pathway: A potential signaling pathway mediating gill hyperplasia and inflammation under ammonia nitrogen stress was identified by multi-omics analysis.
    The Science of the total environment, 2023, Apr-01, Volume: 867

    Topics: Ammonia; Animals; Antioxidants; Gills; Hyperplasia; Inflammation; Multiomics; Nitrogen; Oxidative St

2023
Influence of NOD2 risk variants on hepatic encephalopathy and association with inflammation, bacterial translocation and immune activation.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:8

    Topics: Ammonia; Bacterial Translocation; Female; Hepatic Encephalopathy; Humans; Inflammation; Lipopolysacc

2023
Long-term impact of myocardial inflammation on quantitative myocardial perfusion-a descriptive PET/MR myocarditis study.
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:12

    Topics: Ammonia; Cicatrix; Contrast Media; Coronary Artery Disease; Coronary Circulation; Gadolinium; Humans

2023
Temporal correlations of ferroptosis, inflammation and oxidative stress under acute ammonia exposure in brain tissue of yellow catfish (Pelteobagrus fulvidraco).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2023, Volume: 271

    Topics: Ammonia; Animals; Brain; Catfishes; Ferroptosis; Inflammation; Oxidative Stress

2023
Combined effects of dietary carbohydrate levels and ammonia stress on growth, antioxidant capacity and glucose metabolism in juvenile oriental river prawn (Macrobrachium nipponense).
    Journal of experimental zoology. Part A, Ecological and integrative physiology, 2023, Volume: 339, Issue:10

    Topics: Ammonia; Animals; Antioxidants; Dietary Carbohydrates; Glucose; Inflammation; Palaemonidae; Pyruvate

2023
Chronic Exposure to Environmental Pollutant Ammonia Causes Damage to the Olfactory System and Behavioral Abnormalities in Mice.
    Environmental science & technology, 2023, 10-17, Volume: 57, Issue:41

    Topics: Ammonia; Animals; Cytokines; Environmental Pollutants; Female; Inflammation; Male; Mice; Neoplasms

2023
Anticancer and antibacterial properties of carbon nanotubes are governed by their functional groups.
    Nanoscale, 2023, Nov-23, Volume: 15, Issue:45

    Topics: Ammonia; Animals; Anti-Bacterial Agents; Bacteria; Escherichia coli; Humans; Inflammation; Mammals;

2023
α-lipoic acid ameliorates hepatotoxicity induced by chronic ammonia toxicity in crucian carp (Carassius auratus gibelio) by alleviating oxidative stress, inflammation and inhibiting ERS pathway.
    Ecotoxicology and environmental safety, 2023, Nov-01, Volume: 266

    Topics: Ammonia; Animals; Antioxidants; Carps; Chemical and Drug Induced Liver Injury; Goldfish; Humans; Inf

2023
Application of transcriptome analysis: Oxidative stress, inflammation and microtubule activity disorder caused by ammonia exposure may be the primary factors of intestinal microvilli deficiency in chicken.
    The Science of the total environment, 2019, Dec-15, Volume: 696

    Topics: Air Pollutants; Ammonia; Animals; Antioxidants; Chickens; Down-Regulation; Gene Expression Profiling

2019
Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor.
    Biomaterials, 2019, Volume: 223

    Topics: Ammonia; Animals; Biocompatible Materials; Boranes; Breast Neoplasms; Chlorocebus aethiops; COS Cell

2019
BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats.
    Journal of ethnopharmacology, 2020, Mar-01, Volume: 249

    Topics: Ammonia; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Hepatic Encephalopathy; Inflamma

2020
Effect of acute exposure to ammonia and BFT alterations on Rhynchocypris lagowski: Digestive enzyme, inflammation response, oxidative stress and immunological parameters.
    Environmental toxicology and pharmacology, 2020, Volume: 78

    Topics: Ammonia; Animals; Brain; Complement C3; Complement C4; Cyprinidae; Cytokines; Digestion; Gills; Infl

2020
Combined exposure to hypoxia and ammonia aggravated biological effects on glucose metabolism, oxidative stress, inflammation and apoptosis in largemouth bass (Micropterus salmoides).
    Aquatic toxicology (Amsterdam, Netherlands), 2020, Volume: 224

    Topics: Ammonia; Animals; Antioxidants; Apoptosis; Bass; Blood Glucose; Gene Expression; Gills; Hypoxia; Inf

2020
The inflammatory injury of heart caused by ammonia is realized by oxidative stress and abnormal energy metabolism activating inflammatory pathway.
    The Science of the total environment, 2020, Nov-10, Volume: 742

    Topics: Ammonia; Animals; Chickens; Energy Metabolism; Humans; Inflammation; NF-kappa B; Oxidative Stress

2020
The imbalance of Th1/Th2 triggers an inflammatory response in chicken spleens after ammonia exposure.
    Poultry science, 2020, Volume: 99, Issue:8

    Topics: Ammonia; Animals; Chickens; Cytokines; Gene Expression Regulation; Inflammation; Random Allocation;

2020
Value of monitoring urine ammonia at time of biopsy in patients with lupus nephritis.
    BMC nephrology, 2020, 10-20, Volume: 21, Issue:1

    Topics: Acidosis, Renal Tubular; Ammonia; Atrophy; Biopsy; Creatinine; Female; Fibrosis; Glomerular Filtrati

2020
Exposure to the environmental pollutant ammonia causes changes in gut microbiota and inflammatory markers in fattening pigs.
    Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208

    Topics: Ammonia; Animals; Antioxidants; Biomarkers; Environmental Pollutants; Gastrointestinal Microbiome; I

2021
Ammonia exposure induces oxidative stress and inflammation by destroying the microtubule structures and the balance of solute carriers in the trachea of pigs.
    Ecotoxicology and environmental safety, 2021, Apr-01, Volume: 212

    Topics: Ammonia; Animals; Chickens; Down-Regulation; Environmental Pollutants; Gene Expression Profiling; In

2021
Effect of acute ammonia toxicity on inflammation, oxidative stress and apoptosis in head kidney macrophage of Pelteobagrus fulvidraco and the alleviation of curcumin.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2021, Volume: 248

    Topics: Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Catfishes; Curcumin; Gene Expr

2021
Rhinitis and sleep disorders: The trigeminocardiac reflex link?
    Medical hypotheses, 2017, Volume: 103

    Topics: Ammonia; Carbon Dioxide; Humans; Hypotension; Inflammation; Models, Theoretical; Neurons; Nicotine;

2017
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
    Microbial pathogenesis, 2017, Volume: 113

    Topics: Ammonia; Animals; Citrus; Cytokines; Disease Models, Animal; HEK293 Cells; Humans; I-kappa B Kinase;

2017
Resveratrol Restores Neuronal Tight Junction Proteins Through Correction of Ammonia and Inflammation in CCl
    Molecular neurobiology, 2019, Volume: 56, Issue:7

    Topics: Aldehydes; Ammonia; Animals; Brain; Carbon Tetrachloride; Cytokines; Inflammation; Liver Cirrhosis;

2019
The co-expression of circRNA and mRNA in the thymuses of chickens exposed to ammonia.
    Ecotoxicology and environmental safety, 2019, Jul-30, Volume: 176

    Topics: Ammonia; Animals; Chickens; Gene Expression; Inflammation; Inhalation Exposure; Oxidative Stress; RN

2019
The evaluation of potential immunotoxicity induced by environmental pollutant ammonia in broilers.
    Poultry science, 2019, Aug-01, Volume: 98, Issue:8

    Topics: Air Pollutants; Air Pollution, Indoor; Ammonia; Animal Husbandry; Animals; Chickens; Cytokines; Heat

2019
Differential role of interleukin-1β in neuroinflammation-induced impairment of spatial and nonspatial memory in hyperammonemic rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:9

    Topics: Ammonia; Animal Feed; Animals; Cerebral Cortex; Gene Expression Regulation; Hippocampus; Hyperammone

2019
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:3

    Topics: Ammonia; Animals; Azoxymethane; Blood-Brain Barrier; Cytokines; Disease Models, Animal; Hepatic Ence

2014
A microcycle of inflammation following a team handball game.
    Journal of strength and conditioning research, 2014, Volume: 28, Issue:7

    Topics: Ammonia; Athletic Performance; Blood Glucose; C-Reactive Protein; Creatine Kinase; Cytokines; Exerci

2014
The microcycle of inflammation and performance changes after a basketball match.
    Journal of sports sciences, 2014, Volume: 32, Issue:9

    Topics: Ammonia; Athletic Performance; Basketball; Biomarkers; Blood Glucose; Fatty Acids, Nonesterified; He

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Comparison of inflammatory responses and muscle damage indices following a soccer, basketball, volleyball and handball game at an elite competitive level.
    Research in sports medicine (Print), 2015, Volume: 23, Issue:1

    Topics: Adult; Ammonia; Basketball; Biomarkers; C-Reactive Protein; Case-Control Studies; Creatine Kinase; C

2015
Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study.
    Occupational and environmental medicine, 2015, Volume: 72, Issue:6

    Topics: Adult; Air Pollution, Indoor; Ammonia; Arabs; Barbering; Beauty Culture; Biomarkers; C-Reactive Prot

2015
Antinociceptive and anti-tussive activities of the ethanol extract of the flowers of Meconopsis punicea Maxim.
    BMC complementary and alternative medicine, 2015, May-22, Volume: 15

    Topics: Acetic Acid; Alkaloids; Ammonia; Analgesics; Animals; Anti-Inflammatory Agents; Cough; Flavonoids; F

2015
Oral glutathione supplementation drastically reduces Helicobacter-induced gastric pathologies.
    Scientific reports, 2016, Feb-02, Volume: 6

    Topics: Administration, Oral; Amino Acids; Ammonia; Animals; Carbohydrates; Cell Proliferation; Cytokines; D

2016
Role of ammonia, inflammation, and cerebral oxygenation in brain dysfunction of acute-on-chronic liver failure patients.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2016, Volume: 22, Issue:6

    Topics: Acute-On-Chronic Liver Failure; Adult; Ammonia; Arteries; Biomarkers; Brain; C-Reactive Protein; Fem

2016
In Vitro and In Vivo Toxicity Evaluation of Colloidal Silver Nanoparticles Used in Endodontic Treatments.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Ammonia; Animals; Cell Line; Cell Survival; Connective Tissue; Dental Materials; Dose-Response Relat

2016
Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans.
    Critical care (London, England), 2010, Volume: 14, Issue:1

    Topics: Adult; Amino Acids; Ammonia; Biomarkers; Brain; Humans; Inflammation; Lipopolysaccharides; Male; Ref

2010
The in vitro action of disinfectants and the application of CTAB in the control of Str. agalactiae mastitis.
    The Journal of hygiene, 1946, Volume: 44, Issue:6

    Topics: Ammonia; Animals; Bromides; Cattle; Cetrimonium; Cetrimonium Compounds; Disinfectants; Female; Human

1946
Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy.
    Metabolic brain disease, 2012, Volume: 27, Issue:1

    Topics: Adult; Aged; Ammonia; Cognitive Dysfunction; Fatty Liver; Female; Hepatic Encephalopathy; Humans; Hy

2012
Antitussive, expectorant and anti-inflammatory activities of four alkaloids isolated from Bulbus of Fritillaria wabuensis.
    Journal of ethnopharmacology, 2012, Jan-06, Volume: 139, Issue:1

    Topics: Alkaloids; Ammonia; Animals; Anti-Inflammatory Agents; Antitussive Agents; Cough; Drugs, Chinese Her

2012
[Gender difference of clinical features in Japanese patients with alcoholic liver cirrhosis].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2003, Volume: 38, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Ammonia; Body Mass Index; C-Reactive Protein; Endotoxins; Female; Hum

2003
Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis.
    Journal of hepatology, 2004, Volume: 40, Issue:2

    Topics: Amino Acids; Ammonia; C-Reactive Protein; Female; Hepatic Encephalopathy; Humans; Hyperammonemia; In

2004
Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Adult; Ammonia; Biomarkers; Brain; Cardiovascular System; Cerebrovascular Circulation; Female; Hemod

2004
The role of infection and inflammation in the pathogenesis of hepatic encephalopathy and cerebral edema in acute liver failure.
    Nature clinical practice. Gastroenterology & hepatology, 2006, Volume: 3, Issue:3

    Topics: Ammonia; Animals; Brain Edema; Cytokines; Hepatic Encephalopathy; Humans; Infections; Inflammation;

2006
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:1

    Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrop

2006
Effects of an individually ventilated cage system on the airway integrity of rats (Rattus norvegicus) in a laboratory in Brazil.
    Laboratory animals, 2006, Volume: 40, Issue:4

    Topics: Air Pressure; Ammonia; Animal Husbandry; Animal Welfare; Animals; Animals, Laboratory; Brazil; Bronc

2006
The metabolic changes caused by dexamethasone in the adjuvant-induced arthritic rat.
    Molecular and cellular biochemistry, 2007, Volume: 302, Issue:1-2

    Topics: Alanine; Ammonia; Animals; Arthritis, Experimental; Blood Glucose; Body Weight; Dexamethasone; Fasti

2007
Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:2

    Topics: Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Hepatic Encephalopathy; Ibupr

2007
Ammonia and inflammation in the pathogenesis of hepatic encephalopathy: Pandora's box?
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:2

    Topics: Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Cytokines; Hepatic Encephalop

2007
Changes in plasma, tissue, and urinary nitrogen metabolites due to an inflammatory challenge.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 176, Issue:3

    Topics: Amino Acids; Ammonia; Animals; Chickens; Erythrocytes; Escherichia coli; Hemocyanins; Inflammation;

1984
Effect of misoprostol in ethanol-induced liver injury.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 1995, Volume: 46, Issue:3

    Topics: Alanine Transaminase; Ammonia; Animals; Ethanol; gamma-Glutamyltransferase; Inflammation; Liver; Liv

1995
Quantitative assessment of aerial ammonia toxicity to the nasal mucosa by use of the nasal lavage method in pigs.
    American journal of veterinary research, 1994, Volume: 55, Issue:9

    Topics: Air Pollution, Indoor; Ammonia; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Housing

1994
Effect of hemorrhagic toxin produced by Clostridium sporogenes on rabbit ligated intestinal loop.
    Microbial pathogenesis, 1997, Volume: 22, Issue:1

    Topics: Ammonia; Animals; Bacterial Toxins; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium;

1997
[Effect of ammonia on the pig respiratory system. Study of the dose-response relation].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 1999, Volume: 154, Issue:6 Pt 2

    Topics: Air Pollutants; Ammonia; Animals; Bronchial Hyperreactivity; Capillary Permeability; Cough; Disease

1999
Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease.
    Experimental nephrology, 2001, Volume: 9, Issue:3

    Topics: Ammonia; Ammonium Chloride; Animals; Bicarbonates; Disease Models, Animal; Female; Fibrosis; Inflamm

2001
Expression and activity of pH-regulatory glutaminase in the human airway epithelium.
    American journal of respiratory and critical care medicine, 2002, Jan-01, Volume: 165, Issue:1

    Topics: Acute Disease; Adult; Ammonia; Analysis of Variance; Asthma; Biopsy; Blotting, Western; Breath Tests

2002
Hyperosmolality impairs ammonia-mediated inflammation: implications for the renal medulla.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 2

    Topics: Ammonia; Animals; Cell Degranulation; Complement C3; Humans; Inflammation; Kidney Medulla; Neutrophi

1992
Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Ammonia; Animals; Antigens, Bacterial; Capillary Permeability; Capsaicin; Epithelium; Inflammation;

1991
The erythrocyte as instigator of inflammation. Generation of amidated C3 by erythrocyte adenosine deaminase.
    The Journal of clinical investigation, 1989, Volume: 84, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adult; Ammonia; Coformycin; Complement C3; Erythrocytes; Female; Hum

1989
[Effect of drugs to the reaction experimentally induced by passive cutaneous anaphylaxis, bradykinin, histamine and serotonin].
    Arerugi = [Allergy], 1969, Volume: 18, Issue:6

    Topics: Adrenal Cortex Hormones; Ammonia; Animals; Antifibrinolytic Agents; Bradykinin; Capillary Permeabili

1969
Intestinal ammonia in uraemia: the effect of a urease inhibitor, acetohydroxamic acid.
    Clinical science, 1972, Volume: 42, Issue:1

    Topics: Ammonia; Animals; Blood Proteins; Cecum; Colitis; Colon; Edema; Erythrocytes; Hydroxamic Acids; Infl

1972
[Role of histamine and bradykinin in inflamed lesions].
    Arerugi = [Allergy], 1969, Volume: 18, Issue:6

    Topics: Adrenal Cortex Hormones; Ammonia; Animals; Bradykinin; Drug Antagonism; Histamine; Inflammation; Mic

1969