Page last updated: 2024-10-16

ammonium hydroxide and Huntington Disease

ammonium hydroxide has been researched along with Huntington Disease in 4 studies

azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research Excerpts

ExcerptRelevanceReference
"A reduction in its activity in Huntington's disease may well contribute to the neuronal pathology in certain areas."1.26Glutamine synthetase activity in Huntington's disease. ( Carter, CJ, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carter, CJ2
Aschner, M1
Kimelberg, HK1
Szczepanik-van Leeuwen, PA1

Reviews

1 review available for ammonium hydroxide and Huntington Disease

ArticleYear
The use of astrocytes in culture as model systems for evaluating neurotoxic-induced-injury.
    Neurotoxicology, 1991,Fall, Volume: 12, Issue:3

    Topics: Ammonia; Animals; Astrocytes; Cells, Cultured; Glutamates; Glutamic Acid; Huntington Disease; Metals

1991

Other Studies

3 other studies available for ammonium hydroxide and Huntington Disease

ArticleYear
Loss of glutamine synthetase activity in the brain in Huntington's disease.
    Lancet (London, England), 1981, Apr-04, Volume: 1, Issue:8223

    Topics: Ammonia; Brain; Glutamate Synthase; Humans; Huntington Disease; Transaminases

1981
Glutamine synthetase activity in Huntington's disease.
    Life sciences, 1982, Sep-13, Volume: 31, Issue:11

    Topics: Ammonia; Autopsy; Brain; Glutamate-Ammonia Ligase; Humans; Huntington Disease; Proteins

1982
Improved gas chromatographic-mass spectrometric assay for haloperidol utilizing ammonia chemical ionization and selected-ion monitoring.
    Journal of chromatography, 1985, May-03, Volume: 339, Issue:2

    Topics: Ammonia; Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Haloperidol; Humans; H

1985