Page last updated: 2024-10-16

ammonium hydroxide and Genetic Predisposition

ammonium hydroxide has been researched along with Genetic Predisposition in 6 studies

azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.

Research Excerpts

ExcerptRelevanceReference
"This study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy."7.88Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy. ( Li, X; Zhang, T; Zhao, L; Zhu, X, 2018)
"Valproic acid, which is widely used to treat various types of epilepsy, may cause severe hyperammonemia."7.804217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy. ( Hayashi, H; Imai, K; Inoue, K; Inoue, Y; Itoh, K; Miyakawa, K; Suzuki, E; Takahashi, T; Takahashi, Y; Tsuji, D; Yamamoto, Y; Yazawa, R, 2014)
"This study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy."3.88Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy. ( Li, X; Zhang, T; Zhao, L; Zhu, X, 2018)
"Valproic acid, which is widely used to treat various types of epilepsy, may cause severe hyperammonemia."3.804217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy. ( Hayashi, H; Imai, K; Inoue, K; Inoue, Y; Itoh, K; Miyakawa, K; Suzuki, E; Takahashi, T; Takahashi, Y; Tsuji, D; Yamamoto, Y; Yazawa, R, 2014)
"Systemic hyperammonemia has been largely found in patients with cirrhosis and hepatic encephalopathy, and ammonia plays a major role in the pathogenesis of hepatic encephalopathy."2.45Gut ammonia production and its modulation. ( Galán, JJ; Jover, M; Romero-Gómez, M; Ruiz, A, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Bein, K1
Ganguly, K1
Martin, TM1
Concel, VJ1
Brant, KA1
Di, YPP1
Upadhyay, S1
Fabisiak, JP1
Vuga, LJ1
Kaminski, N1
Kostem, E1
Eskin, E1
Prows, DR1
Jang, AS1
Leikauf, GD1
Wei, YL1
Tian, Q1
Zhao, XX1
Qiu, GZ1
Xu, Y1
Zhu, X1
Li, X1
Zhang, T1
Zhao, L1
Inoue, K1
Suzuki, E1
Takahashi, T1
Yamamoto, Y1
Yazawa, R1
Takahashi, Y1
Imai, K1
Miyakawa, K1
Inoue, Y1
Tsuji, D1
Hayashi, H1
Itoh, K1
Mitchell, S1
Ellingson, C1
Coyne, T1
Hall, L1
Neill, M1
Christian, N1
Higham, C1
Dobrowolski, SF1
Tuchman, M1
Summar, M1
Romero-Gómez, M1
Jover, M1
Galán, JJ1
Ruiz, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Longitudinal Study of Urea Cycle Disorders[NCT00237315]1,009 participants (Anticipated)Observational2006-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ammonium hydroxide and Genetic Predisposition

ArticleYear
Gut ammonia production and its modulation.
    Metabolic brain disease, 2009, Volume: 24, Issue:1

    Topics: Ammonia; Animals; Genetic Predisposition to Disease; Glutaminase; Glutamine; Hepatic Encephalopathy;

2009

Other Studies

5 other studies available for ammonium hydroxide and Genetic Predisposition

ArticleYear
Genetic determinants of ammonia-induced acute lung injury in mice.
    American journal of physiology. Lung cellular and molecular physiology, 2021, 01-01, Volume: 320, Issue:1

    Topics: Acute Lung Injury; Ammonia; Animals; Female; Gene Expression Regulation; Genetic Markers; Genetic Pr

2021
Association between MFN2 gene polymorphisms and the risk and prognosis of acute liver failure: a case-control study in a Chinese population.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, May-15, Volume: 50, Issue:6

    Topics: Adult; Ammonia; Asian People; Case-Control Studies; China; Female; Gene Frequency; Genetic Predispos

2017
Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:5

    Topics: Age Factors; Ammonia; Anticonvulsants; Aspartate Aminotransferases; Chemical and Drug Induced Liver

2018
4217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy.
    Epilepsy research, 2014, Volume: 108, Issue:6

    Topics: Alleles; Amino-Acid N-Acetyltransferase; Ammonia; Anticonvulsants; Asian People; Biomarkers, Pharmac

2014
Genetic variation in the urea cycle: a model resource for investigating key candidate genes for common diseases.
    Human mutation, 2009, Volume: 30, Issue:1

    Topics: Ammonia; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Aciduria; C

2009