ammonium hydroxide has been researched along with Disease Models, Animal in 281 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Urea cycle disorders with hyperammonemia remain difficult to treat and eventually necessitate liver transplantation." | 8.12 | Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model. ( Burczynski, ME; Chen, H; Cheng, X; Halasz, G; Kim, S; Lin, AZ; Mao, X; Murphy, AJ; Na, E; Okamoto, H; Sleeman, MW, 2022) |
| " Low-grade chronic liver failure (CLF) was induced in 3-month old Sprague-Dawley male rats using thioacetamide (TAA, 50 mg·kg-1·day-1) intraperitoneally for 2 weeks." | 7.85 | Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats. ( Ali, SS; Gazzaz, ZJ; Ibraheem, MS; Murad, HA, 2017) |
| "Short-term administration of Galactosamine to experimental animals causes liver damage and acute liver failure (ALF), as well as acute renal failure in some cases." | 7.81 | D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure? ( Brytan, M; Dyrla, P; Gil, J; Kade, G; Nowak, Z; Patera, J; Saracyn, M; Wańkowicz, Z; Zdanowski, R, 2015) |
| "Citrullinemia type 1 (CTLN1) is an autosomal recessive disorder of metabolism caused by a deficiency of argininosuccinate synthetase." | 7.79 | Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1. ( Chandler, RJ; Cusmano-Ozog, K; McGuire, PJ; Sun, Q; Sutton, VR; Tarasenko, TN; Venditti, CP, 2013) |
| " The present study was undertaken to examine the protective influence of rutin, a polyphenolic flavonoid, on oxidative stress during ammonium chloride (AC)-induced hyperammonemia by measuring the levels of oxidative damage as well as antioxidant status." | 7.78 | Influence of rutin on biochemical alterations in hyperammonemia in rats. ( Mahmoud, AM, 2012) |
| " We examined the modulatory effect of the type 1 angiotensin II receptor blocker losartan on the ability of metabolic acidosis to stimulate ammonia production and secretion by mouse S2 proximal tubule segments." | 7.74 | Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis. ( Nagami, GT, 2008) |
| "The objective of this study was to evaluate a new method for the treatment of acute hyperammonemia with a helium-oxygen mixture (heliox)." | 7.71 | Heliox use in the treatment of acute hyperammonemia. ( Barr, J; Chen-Levy, Z; Eshel, G; Lahat, E, 2001) |
| "Therapeutic modulation of the increased GABAergic tone in chronic hepatic encephalopathy (HE) by the benzodiazepine receptor (BR) antagonist flumazenil (F) has led to conflicting results in humans and animal models for HE." | 7.70 | Improvement of chronic hepatic encephalopathy in dogs by the benzodiazepine-receptor partial inverse agonist sarmazenil, but not by the antagonist flumazenil. ( Legemate, DA; Meyer, HP; Rothuizen, J; van den Brom, W, 1998) |
| "Hepatic encephalopathy in patients with severe liver disease was associated with marked elevation of either serum methionine or blood ammonia levels or with simultaneous moderate increases in both parameters." | 7.66 | Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy. ( Higashi, T, 1982) |
| " One of the biggest problems of these compounds, however, is their very short bioavailability due to instant metabolism and rapid excretion." | 5.51 | Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury. ( Ibayashi, Y; Lee, Y; Nagasaki, Y; Ngo, DN; Nishikawa, Y; Vong, LB, 2019) |
| "Treatment with rutin resulted in improvement in liver function by the decline in serum AST and ALT activities and reduction in serum ammonia level." | 5.46 | Ameliorative effects of rutin on hepatic encephalopathy-induced by thioacetamide or gamma irradiation. ( El-Marakby, SM; Mansour, SZ; Moawed, FSM, 2017) |
| "Hepatic encephalopathy is a severe neuropathological condition arising secondary to liver failure." | 5.35 | Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia. ( Bak, LK; Iversen, P; Keiding, S; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS, 2009) |
| "The rationale for recommendation of branched-chain amino acids (BCAA; valine, leucine, and isoleucine) in treatment of liver failure is based on their unique pharmacologic properties, stimulatory effect on ammonia detoxification to glutamine (GLN), and decreased concentrations in liver cirrhosis." | 4.89 | Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications. ( Holecek, M, 2013) |
| "Life-threatening hyperammonemia occurs in both inherited and acquired liver diseases affecting ureagenesis, the main pathway for detoxification of neurotoxic ammonia in mammals." | 4.12 | O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis. ( Arena, P; Attanasio, S; Boffa, I; Brunetti-Pierri, N; Cuomo, P; D'Alessio, AM; De Angelis, A; Desviat, LR; Ferenbach, AT; Häberle, J; Lipshutz, GS; Makris, G; Martínez-Pizarro, A; Motta, A; Nitzahn, M; Nusco, E; Paris, D; Pravata, VM; Richard, E; Rüfenacht, V; Soria, LR; van Aalten, DMF, 2022) |
| " Urea cycle disorders with hyperammonemia remain difficult to treat and eventually necessitate liver transplantation." | 4.12 | Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model. ( Burczynski, ME; Chen, H; Cheng, X; Halasz, G; Kim, S; Lin, AZ; Mao, X; Murphy, AJ; Na, E; Okamoto, H; Sleeman, MW, 2022) |
| "Arginase deficiency is caused by biallelic mutations in arginase 1 (ARG1), the final step of the urea cycle, and results biochemically in hyperargininemia and the presence of guanidino compounds, while it is clinically notable for developmental delays, spastic diplegia, psychomotor function loss, and (uncommonly) death." | 3.91 | Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency. ( Allegri, G; Burke, KE; Cederbaum, SD; Häberle, J; Lipshutz, GS; Liu, XB; Martini, PGV; Truong, B; Zhu, X, 2019) |
| " Low-grade chronic liver failure (CLF) was induced in 3-month old Sprague-Dawley male rats using thioacetamide (TAA, 50 mg·kg-1·day-1) intraperitoneally for 2 weeks." | 3.85 | Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats. ( Ali, SS; Gazzaz, ZJ; Ibraheem, MS; Murad, HA, 2017) |
| "Short-term administration of Galactosamine to experimental animals causes liver damage and acute liver failure (ALF), as well as acute renal failure in some cases." | 3.81 | D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure? ( Brytan, M; Dyrla, P; Gil, J; Kade, G; Nowak, Z; Patera, J; Saracyn, M; Wańkowicz, Z; Zdanowski, R, 2015) |
| "Citrullinemia type 1 (CTLN1) is an autosomal recessive disorder of metabolism caused by a deficiency of argininosuccinate synthetase." | 3.79 | Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1. ( Chandler, RJ; Cusmano-Ozog, K; McGuire, PJ; Sun, Q; Sutton, VR; Tarasenko, TN; Venditti, CP, 2013) |
| " Current knowledge suggests that hyperammonemia, related to liver failure, is a main factor contributing to the cerebral alterations in HE and that hyperammonemia might impair signal transduction associated with post-translational modification of proteins such as tyrosine-nitration and phosphorylation." | 3.78 | Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models. ( Airoldi, L; Boix, J; Brunelli, L; Campagna, R; Cauli, O; Felipo, V; Llansola, M; Pastorelli, R, 2012) |
| " The present study was undertaken to examine the protective influence of rutin, a polyphenolic flavonoid, on oxidative stress during ammonium chloride (AC)-induced hyperammonemia by measuring the levels of oxidative damage as well as antioxidant status." | 3.78 | Influence of rutin on biochemical alterations in hyperammonemia in rats. ( Mahmoud, AM, 2012) |
| "Ornithine phenylacetate (OP) is a new drug that has been proposed for the treatment of hepatic encephalopathy (HE) because it decreases plasma ammonia." | 3.78 | Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis. ( Arranz, JA; Córdoba, J; Oria, M; Raguer, N; Riudor, E; Romero-Giménez, J, 2012) |
| "Hyperammonemia is a frequent side-effect of valproic acid (VPA) therapy, which points to an imbalance between ammoniagenesis and ammonia disposal via the urea cycle." | 3.77 | New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA. ( Aires, CC; de Almeida, IT; Duran, M; Ijlst, L; Silva, MF; van Cruchten, A; Wanders, RJ, 2011) |
| " The aim of this study was to assess the effects of simvastatin on rats with TAA-induced acute liver damage and hepatic encephalopathy." | 3.74 | Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy. ( Chan, CY; Chang, FY; Chen, YC; Chu, CJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS, 2008) |
| " plantarum strains were administered in ornithine transcarbamoylase-deficient Sparse-fur mice, a model of constitutive hyperammonemia, in a carbon tetrachloride rat model of chronic liver insufficiency and in a thioacetamide-induced acute liver failure mice model." | 3.74 | Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents. ( Demetter, P; Devière, J; Goffin, P; Gustot, T; Hols, P; Moreno, C; Nicaise, C; Prozzi, D; Quertinmont, E; Suain, V; Viaene, E, 2008) |
| " Liver failure with significant increase in serum concentration of bilirubin, alanine transaminase (ALT) and ammonia, as well as huge microscopic necrosis of hepatocytes developed in both groups, but we did not achieved any evidence of acute renal failure in Wistar rats group." | 3.74 | [Race of experimental animals and development of renal failure in animal model of hepatorenal syndrome]. ( Kozłowski, W; Nowak, Z; Patera, J; Saracyn, M; Wańkowicz, Z; Wesołowski, P, 2008) |
| " We examined the modulatory effect of the type 1 angiotensin II receptor blocker losartan on the ability of metabolic acidosis to stimulate ammonia production and secretion by mouse S2 proximal tubule segments." | 3.74 | Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis. ( Nagami, GT, 2008) |
| "To assess whether portacaval anastomosis (PCA) in rats affects the protein expression and/or activity of glutaminase in kidneys, intestines and in three brain areas of cortex, basal ganglia and cerebellum and to explain the neurological alterations found in hepatic encephalopathy (HE)." | 3.73 | Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis. ( Bautista, JD; Camacho, I; de Teran, LC; Diaz-Gomez, D; Echevarria, M; Felipo, V; Jover, M; Rodrigo, R; Romero-Gomez, M, 2006) |
| " Liver failure developed with significant increase in serum concentration of bilirubin, AST, ALT; ammonia and massive necrosis of hepatocytes." | 3.72 | [Description of an experimental model of hepatorenal syndrome in Wistar rats]. ( Kozłowski, W; Saracyn, M; Wańikowicz, Z, 2004) |
| " Indomethacin induced gastritis but without atrophy, and short-term vitamin deficiency failed to induce chronic gastritis and gastric atrophy." | 3.72 | Chronic gastritis rat model and role of inducing factors. ( Huang, HD; Si, JM; Xiang, Z, 2004) |
| " We have conducted studies to determine whether the protection afforded by the administration of sodium bicarbonate is sustained and prevents development of uremia during chronic administration and whether the effects of the administration of ammonium chloride and sodium bicarbonate are also observed in a different model of polycystic kidney disease, the CD1-pcy/pcy mouse." | 3.71 | Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease. ( Branden, MG; Cowley, BD; Gattone, VH; Torres, VE; Yoshida, I, 2001) |
| "The objective of this study was to evaluate a new method for the treatment of acute hyperammonemia with a helium-oxygen mixture (heliox)." | 3.71 | Heliox use in the treatment of acute hyperammonemia. ( Barr, J; Chen-Levy, Z; Eshel, G; Lahat, E, 2001) |
| "Therapeutic modulation of the increased GABAergic tone in chronic hepatic encephalopathy (HE) by the benzodiazepine receptor (BR) antagonist flumazenil (F) has led to conflicting results in humans and animal models for HE." | 3.70 | Improvement of chronic hepatic encephalopathy in dogs by the benzodiazepine-receptor partial inverse agonist sarmazenil, but not by the antagonist flumazenil. ( Legemate, DA; Meyer, HP; Rothuizen, J; van den Brom, W, 1998) |
| "Portocaval shunt with common bile duct transection produces liver failure with elevations in aminotransferases, total bilirubin, and ammonia, a decreased branched chain to aromatic amino acid ratio, and histologic inflammation." | 3.70 | A novel stable reproducible model of hepatic failure in canines. ( Awad, SS; Bartlett, RH; Gargulinski, M; Hemmila, MR; Hirschl, RB; Mahler, S; Rich, PB; Sawada, S; Soldes, OS, 2000) |
| "Intracerebral microdialysis was applied to monitor the neocortical extracellular levels of the aromatic amino acids phenylalanine, tyrosine, and tryptophan, the neurotransmitters dopamine (DA), noradrenaline (NA), and serotonin (5-HT), and the metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindole-3-acetic acid (5-HIAA) in rats with various forms of experimental hepatic encephalopathy (HE)." | 3.69 | Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt. ( Bengtsson, F; Bergqvist, PB; Bosman, DK; Chamuleau, RA; Hjorth, S; Maas, MA; Vogels, BA, 1995) |
| "We investigated the role of brain peripheral-type benzodiazepine receptors (PBRs) and pregnenolone (a product of PBRs activation) in hepatic encephalopathy (HE)/hyperammonemia." | 3.69 | Acute liver failure and hyperammonemia increase peripheral-type benzodiazepine receptor binding and pregnenolone synthesis in mouse brain. ( Dombro, RS; Itzhak, Y; Norenberg, MD; Roig-Cantisano, A, 1995) |
| "To obtain a more precise pathophysiological evaluation of the role of ammonia in acute hepatic encephalopathy, we compared the plasma ammonia concentrations and electroencephalographic recordings (EEGs) of rabbits with surgically induced acute hepatic failure (AHF, n = 10) and normal rabbits administered an infusion of ammonium acetate (NH4-Ac, n = 7) over a 10-hr period." | 3.67 | Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits. ( de Vlieger, M; Fick, TE; Schalm, SW, 1989) |
| "To assess neuronal mechanisms of potential importance in the pathogenesis of hepatic encephalopathy, visual evoked potentials were recorded in rabbits with acute hyperammonemic encephalopathy, postictal coma, and toxin-induced coma resulting from the administration of a combination of subcoma doses of three neurotoxins: ammonia, dimethyldisulfide, and octanoic acid." | 3.67 | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. ( Ferenci, P; Jones, EA; Pappas, SC; Schafer, DF, 1984) |
| "Hepatic encephalopathy in patients with severe liver disease was associated with marked elevation of either serum methionine or blood ammonia levels or with simultaneous moderate increases in both parameters." | 3.66 | Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy. ( Higashi, T, 1982) |
| "Hyperammonemia is a feature of liver failure, which is associated with increased risk of infection." | 2.73 | Ammonia impairs neutrophil phagocytic function in liver disease. ( Davies, NA; Hodges, SJ; Jalan, R; Pitsillides, AA; Shawcross, DL; Stadlbauer, V; Wheeler-Jones, C; Wright, GA, 2008) |
| "Mycophenolic acid was detected in all cats." | 2.61 | ( Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z, 2019) |
| "The current treatments for hyperammonemia, such as antibiotics or lactulose, are designed to decrease the intestinal production of ammonia and/or its absorption into the body and are not effective, besides being often accompanied by side effects." | 2.58 | The Pharmabiotic Approach to Treat Hyperammonemia. ( Chung, HJ; Hong, ST; Kim, HJ; Liu, J; Lkhagva, E, 2018) |
| "In regards to hepatic encephalopathy, however, the CCl4 cirrhosis rat model seems to display few behavioral changes unless very advanced decompensated cirrhosis is produced." | 2.39 | Animal models of hepatic encephalopathy and hyperammonemia. ( Birgisson, S; Conjeevaram, H; Gacad, RC; Mullen, KD, 1994) |
| "We successfully established a reproducible Tibetan miniature pig model of d-galactosamine-induced ALF, and we believe that a dosage of 0." | 1.91 | Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system. ( Cai, L; Feng, L; Fu, Y; Gao, Y; Jiang, Z; Liu, S; Wang, Y; Xu, X; Zhang, L; Zhou, C, 2023) |
| "In nonalcoholic fatty liver disease (NAFLD), fibrosis is the most important factor contributing to NAFLD-associated morbidity and mortality." | 1.56 | Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease. ( Andreola, F; Davies, N; De Chiara, F; Gracia-Sancho, J; Habtesion, A; Hall, A; Jalan, R; Jones, H; Leslie, J; Manicardi, N; Mann, J; Mookerjee, RP; Oakley, F; Paish, HL; Reed, LH; Rombouts, K; Thomsen, KL; Watson, AA, 2020) |
| "Methylenedioxymethamphetamine (MDMA) and methcathinone (MCAT) are abused psychostimulant drugs that produce adverse effects in human users that include hepatotoxicity and death." | 1.56 | High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone. ( Chen, Y; Hall, FS; Saber, YH; Tran, HTN, 2020) |
| "Inflammation is likely an important target of BBD to treat HE." | 1.56 | BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats. ( An, YT; Bahaji Azami, NL; Lu, BJ; Lu, L; Sun, MY; Wang, HJ; Wang, Z; Wu, C; Xie, D; Ye, G, 2020) |
| " One of the biggest problems of these compounds, however, is their very short bioavailability due to instant metabolism and rapid excretion." | 1.51 | Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury. ( Ibayashi, Y; Lee, Y; Nagasaki, Y; Ngo, DN; Nishikawa, Y; Vong, LB, 2019) |
| "The development of fibrosis is the most important factor contributing to NASH-associated morbidity and mortality." | 1.48 | Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis. ( Andreola, F; De Chiara, F; Jalan, R; Mookerjee, RP; Rombouts, K; Thomsen, KL; Vilstrup, H, 2018) |
| "Neurological symptoms of acute liver failure (ALF) reflect decreased excitatory transmission, but the status of ALF-affected excitatory synapse has not been characterized in detail." | 1.48 | Cortical Synaptic Transmission and Plasticity in Acute Liver Failure Are Decreased by Presynaptic Events. ( Albrecht, J; Bobula, B; Filipkowski, RK; Frontczak-Baniewicz, M; Hess, G; Polowy, R; Popek, M; Sowa, J; Zabłocka, B; Zielińska, M, 2018) |
| "Hyperammonemia is a common finding in patients with methylmalonic acidemia." | 1.48 | Ammonia role in glial dysfunction in methylmalonic acidemia. ( Arend, J; Barbosa, S; do Nascimento, PS; Dos Santos, ARS; Fighera, MR; Furian, AF; Gabbi, P; Haupental, F; Nogueira, V; Oliveira, MS; Rodrigues, FS; Royes, LFF, 2018) |
| "We successfully established a simplified, reproducible D-galactosamine-induced cynomolgus monkey model of acute liver failure, and the single or divided dosage of 0." | 1.46 | Novel D-galactosamine-induced cynomolgus monkey model of acute liver failure. ( Cai, L; Feng, L; Gao, Y; He, GL; Jiang, ZS; Li, Y; Pan, MX; Peng, Q; Weng, J, 2017) |
| "Treatment with rutin resulted in improvement in liver function by the decline in serum AST and ALT activities and reduction in serum ammonia level." | 1.46 | Ameliorative effects of rutin on hepatic encephalopathy-induced by thioacetamide or gamma irradiation. ( El-Marakby, SM; Mansour, SZ; Moawed, FSM, 2017) |
| "Hyperammonemia is a consistent abnormality in cirrhosis that results in impaired skeletal muscle protein synthesis and breakdown (proteostasis)." | 1.46 | Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. ( Dasarathy, S; Davuluri, G; Deutz, NEP; Engelen, MPKJ; Kumar, A; Prayson, R; Silva, RNE; Ten Have, GAM, 2017) |
| "Muscle mass loss and hepatic encephalopathy (complex neuropsychiatric disorder) are serious complications of chronic liver disease (cirrhosis) which impact negatively on clinical outcome and quality of life and increase mortality." | 1.46 | The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis. ( Bemeur, C; Bosoi, CR; Deutz, NE; Ochoa-Sanchez, R; Oliveira, MM; Rose, CF; Ten Have, GA; Tremblay, M, 2017) |
| "Understanding the seizure-inducing mechanisms of TBI is of the utmost importance, because these seizures are often resistant to traditional first- and second-line anti-seizure treatments." | 1.46 | NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility. ( Cotrina, ML; Gu, S; He, X; Huang, JH; Liu, W; Nedergaard, M; Shapiro, LA; Wang, EW; Wang, F; Wang, W; Wang, X, 2017) |
| "The pathogenesis of hepatic encephalopathy (HE) in cirrhosis is multifactorial and ammonia is thought to play a key role." | 1.46 | Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease. ( Davies, N; De Chiara, F; Gourine, AV; Habtetion, A; Hadjihambi, A; Hosford, PS; Jalan, R; Karagiannis, A, 2017) |
| " Rifaximin, a poorly absorbed antibiotic that targets gut flora, significantly improved symptoms of HE." | 1.43 | Development of an experimental rat model of hyperammonemic encephalopathy and evaluation of the effects of rifaximin. ( Fukui, N; Isobe, M; Okada, M; Saito, T; Suzuki, H; Tamaoki, S, 2016) |
| "Hyperammonemia is less severe in arginase 1 deficiency compared with other urea cycle defects." | 1.42 | Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy. ( Cantero, G; Cantero-Nieto, G; Cederbaum, SD; Chan, E; Hu, C; Lipshutz, GS; Park, H; Tai, DS; Yudkoff, M, 2015) |
| "Glycine is an important ammoniagenic amino acid, which is increased in acute liver failure (ALF)." | 1.40 | L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway. ( Fuskevåg, OM; Jalan, R; Kristiansen, RG; Mæhre, H; Revhaug, A; Rose, CF; Ytrebø, LM, 2014) |
| "In a rat model of chronic liver failure, hyperammonemia is associated with inadequate compensation by liver and muscle GS activity and increased gut GA activity." | 1.40 | Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats. ( Davies, N; Habtesion, A; Jalan, R; Jover-Cobos, M; Lee, K; Noiret, L; Romero-Gomez, M; Sharma, V, 2014) |
| "Mortality of patients with acute liver failure (ALF) is still unacceptably high." | 1.39 | Evaluation of the Hepa Wash® treatment in pigs with acute liver failure. ( Al-Chalabi, A; Huber, W; Kreymann, B; Luppa, P; Matevossian, E; Nairz, E; Neiss, A; Perren, A; Radermacher, P; Schimmel, P; Schmid, RM; Schreiber, C; Schuster, T; V Thaden, AK; Yang, Z, 2013) |
| "Uric acid has also antioxidant properties and is a surrogate marker of metabolic syndrome." | 1.38 | Long-term activation of semicarbazide-sensitive amine oxidase lowers circulating levels of uric acid in diabetic conditions. ( Carpéné, C; Desquesnes, A; Gomez-Ruiz, A; Iffiú-Soltész, Z; Le Gonidec, S; Mercader, J, 2012) |
| " The results show that a binge dosing regimen of METH to the rat increased plasma and brain ammonia concentrations that were paralleled by evidence of hepatotoxicity." | 1.38 | Peripheral ammonia as a mediator of methamphetamine neurotoxicity. ( Halpin, LE; Yamamoto, BK, 2012) |
| "is widely used for the treatment of cough, bronchitis and asthmatic disorders in the Traditional Chinese Medicine." | 1.38 | Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice. ( Jia, JP; Li, ZY; Qin, XM; Sun, HF; Xing, J; Xue, SY; Zhang, FS; Zhang, LZ; Zhi, HJ, 2012) |
| "However, HE in patients with liver cirrhosis is not associated with an up-regulation of inflammatory cytokines in cerebral cortex, despite microglia activation." | 1.37 | Microglia activation in hepatic encephalopathy in rats and humans. ( Bidmon, HJ; Görg, B; Häussinger, D; Keitel, V; Schrör, K; Zemtsova, I, 2011) |
| "The pathophysiology of cerebral edema in ALF is incompletely understood." | 1.37 | Ammonia-induced brain swelling and neurotoxicity in an organotypic slice model. ( Back, A; Bai, T; Brorson, JR; Chiranand, P; Frank, JI; Goldenberg, FD; Tupper, KY, 2011) |
| "Acute liver failure was surgically induced in swine by complete hepatectomy (n = 8)." | 1.37 | Neuromonitoring in a porcine model of acute hepatic failure. ( Frühauf, NR; Grabellus, F; Kaiser, GM; Laube, T; Radunz, S; Uerschels, AK, 2011) |
| "Hyperammonemia is considered to be the main cause of decreased levels of the branched-chain amino acids (BCAA), valine, leucine, and isoleucine, in liver cirrhosis." | 1.37 | Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle. ( Holecek, M; Kandar, R; Kovarik, M; Sispera, L, 2011) |
| "To develop a reliable surgical model of acute hepatic failure and hyperammonemia in rats that avoids porto-systemic shunt and bile duct ligation, applicable to hepatic encephalopathy research." | 1.36 | A new experimental model for acute hepatic failure in rats. ( Bellodi-Privato, M; D'Albuquerque, LA; Kubrusly, MS; Leite, KR; Machado, MC; Molan, NT; Teixeira, AR, 2010) |
| "Hyperammonemia is a main contributor to brain herniation and mortality in acute liver failure (ALF)." | 1.35 | Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain. ( Agusti, A; Boix, J; Cauli, O; Felipo, V; Piedrafita, B; Rodrigo, R, 2008) |
| "Myocardial infarction was induced by mid-left anterior descending coronary artery balloon occlusion in 11 pigs." | 1.35 | Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction. ( Abraham, MR; Ashikaga, H; Bengel, FM; Chang, KC; Dannals, RF; Dong, J; Halperin, H; Hilton, J; Holt, DP; Lardo, AC; Marbán, E; Mills, KJ; Nekolla, SG; Sasano, T, 2008) |
| "After transplantation into mice with acute liver failure, ASC-derived hepatocytes can restore such liver functions as ammonia and purine metabolism." | 1.35 | Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure. ( Banas, A; Kato, T; Ochiya, T; Okochi, H; Osaki, M; Takeshita, F; Teratani, T; Tokuhara, M; Yamamoto, Y, 2009) |
| "Hepatic encephalopathy is a severe neuropathological condition arising secondary to liver failure." | 1.35 | Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia. ( Bak, LK; Iversen, P; Keiding, S; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS, 2009) |
| "Patients with acute liver failure (ALF) display impairment of cerebral blood flow (CBF) autoregulation, which may contribute to the development of fatal intracranial hypertension, but the pathophysiological mechanism remains unclear." | 1.35 | Cerebral blood flow autoregulation in experimental liver failure. ( Dethloff, TJ; Knudsen, GM; Larsen, FS, 2008) |
| "LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier." | 1.34 | Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007) |
| "We previously demonstrated in pigs with acute liver failure (ALF) that albumin dialysis using the molecular adsorbents recirculating system (MARS) attenuated a rise in intracranial pressure (ICP)." | 1.34 | Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure. ( Belanger, M; Davies, NA; Jalan, R; Nedredal, GI; Revhaug, A; Rose, C; Sen, S; Ytrebø, LM, 2007) |
| "The initial development of cerebral edema and increased ICP occurs independently of CBF changes in this noninflammatory model of ALF." | 1.33 | Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study. ( Butterworth, RF; Davies, NA; Deutz, NE; Drevland, SS; Hodges, SJ; Jalan, R; Kjønnø, M; Nedredal, GI; Prinzen, FW; Revhaug, A; Rose, C; Sen, S; Williams, R; Ytrebø, LM, 2006) |
| "In the experiments of BAL in vitro, acute liver failure (ALF) model in canine was induced by an end-side portocaval shunt combined with common bile duct ligation and transaction." | 1.33 | Functional evaluation of a new bioartificial liver system in vitro and in vitro. ( Chen, Z; Ding, YT, 2006) |
| "Latex allergy is important due to serious health impacts and widespread use of its products." | 1.33 | A latex-induced allergic airway inflammation model in mice. ( Farzaneh, P; Hassan, ZM; Hogan, SP; Hoseini, AZ; Pourpak, Z, 2006) |
| " Dose-response curves were constructed for the inflammatory reactions induced in nasal cavities, the smooth muscle hyperresponsiveness in the trachea, the permeability of alveolo-capillary barrier, the pulmonary vasomotricity, the cough reflex and the systemic effects." | 1.30 | [Effect of ammonia on the pig respiratory system. Study of the dose-response relation]. ( Gustin, P, 1999) |
| "When lactitol was given orally twice a day for 7 days at doses of 3 and 10 g/kg/day and at half that daily dose on day 8, it significantly decreased the ammonium concentration of the portal blood by 27." | 1.29 | Mechanism for lowering blood ammonia levels by lactitol. ( Hirata, Y; Kimura, K; Niida, H; Ozaki, T; Ueda, F; Watanabe, M; Yamamoto, O; Yoshikuni, Y, 1995) |
| "Two experimental hepatic comatose models with combined-type symptom were developed in rats." | 1.29 | [Effect of lactitol (NS-4) on the increase in blood and brain ammonia concentration and on coma in newly developed rat models of hepatic coma]. ( Hirata, Y; Kimura, K; Ozaki, T; Watanabe, M; Yoshikuni, Y, 1995) |
| "Hyperammonemic encephalopathy has occasionally been reported in uremic patients receiving hyperalimentation with essential amino acid (EAA) as a source of nitrogen as one of the remaining treatment options when the enteric routes were prohibited." | 1.29 | Hyperammonemic encephalopathy due to essential amino acid hyperalimentation. ( Chang, CJ; Chen, WJ; Huang, SM; Lai, HS; Lee, JC; Wang, ST, 1994) |
| "Acute liver failure was induced by two-stage liver devascularization, and acute hyperammonemia by prolonged ammonia infusion such that the plasma ammonia pattern found in acute liver failure was simulated." | 1.29 | Encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit. A clinical and biochemical study. ( de Knegt, RJ; Groeneweg, M; Hekking-Weijma, I; Schalm, SW, 1994) |
| "The homovanillic acid content was significantly increased in the hypothalamus, hippocampus/substantia nigra and brainstem." | 1.29 | Tyrosine uptake and regional brain monoamine metabolites in a rat model resembling congenital hyperammonemia. ( Bachmann, C; Cervantes, H; Colombo, JP; Kokorovic, M; Perritaz, R, 1996) |
| "Lactitol and lactulose were compared in their effect on the concentrations of ammonia and amino acids in blood and cerebrospinal fluid (CSF) in Eck fistula dogs." | 1.29 | [The effect of lactitol (NS-4) on the concentrations of ammonia and amino acids in blood and cerebrospinal fluid in Eck fistula (portacaval-shunted) dogs]. ( Hirata, Y; Kimura, K; Ozaki, T; Sato, S; Suzuki, K; Watanabe, M; Yoshikuni, Y, 1995) |
| "Ibuprofen treatment, either solely or in combination with influenza infection, did not produce significant change in the plasma levels of aspartate or ornithine aminotransferase activities." | 1.28 | Interactions of ibuprofen with influenza infection and hyperammonemia in an animal model of Reye's syndrome. ( Deshmukh, DR; Mukhopadhyay, A; Sarnaik, AP, 1992) |
| "Galactosamine-induced hepatic coma is not associated with any functionally significant changes in the molecular components of the postsynaptic dopamine receptor." | 1.27 | [Pathogenesis of hepatic encephalopathy--studies in the rabbit model of acute liver failure]. ( Ferenci, P; Jones, EA; Pappas, SC; Schafer, DF, 1984) |
| "Effects of influenza B infection, aspirin treatment and hyperammonemia on the level of free fatty acids, total lipids and triacylglycerols in serum and liver of an animal model of Reye's syndrome are reported here." | 1.27 | Free fatty acids in an animal model of Reye's syndrome. ( Deshmukh, DR; Deshmukh, GD; Radin, NS; Shope, TC, 1983) |
| "Reye's syndrome is a serious childhood disorder that develops following influenza infections and is characterized in part by an encephalopathy, hyperammonemia and elevated serum transaminases." | 1.27 | Arginine deficiency, hyperammonemia and Reye's syndrome in ferrets. ( Deshmukh, DR; Thomas, PE, 1985) |
| "One theory of the etiology of Reye's syndrome is that environmental toxins predispose the child to react abnormally to virus infection." | 1.27 | Biochemical and morphological characteristics of a mouse model of Reye's syndrome induced by the interaction of influenza B virus and a chemical emulsifier. ( Crocker, JF; Digout, SC; Lee, SH; Malatjalian, DA; Renton, KW; Rozee, KR, 1986) |
| "Thus, many of the abnormalities seen in Reye's syndrome were seen in this model; however, there were no hepatic enzyme changes despite altered mitochondrial morphology and no evidence of cerebral edema despite a florid encephalopathy." | 1.27 | Investigation of an animal model of a Reye-like syndrome caused by Margosa oil. ( Arcinue, EL; Mitchell, RA; Schwartz, PH; Sinniah, D, 1985) |
| "Recent studies of Reye syndrome (RS) patients have suggested aspirin treatment as a possible factor in the etiology of this often fatal childhood disorder." | 1.26 | Interactions of aspirin and other potential etiologic factors in an animal model of Reye syndrome. ( Deshmukh, DR; Maassab, HF; Mason, M, 1982) |
| "Current theories on the pathogenesis of hepatic coma indicate that intestinal bacteria produce cerebral toxins, such as ammonia, mercaptans, and short-chain fatty acids." | 1.26 | Hyperammonemic coma after hepatectomy in germ-free rats. ( Schalm, SW; van der Mey, T, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (25.98) | 18.7374 |
| 1990's | 51 (18.15) | 18.2507 |
| 2000's | 49 (17.44) | 29.6817 |
| 2010's | 87 (30.96) | 24.3611 |
| 2020's | 21 (7.47) | 2.80 |
| Authors | Studies |
|---|---|
| Kaviani, A | 1 |
| Khansari Nejad, N | 1 |
| Akour, A | 1 |
| AlMuhaissen, SA | 1 |
| Nusair, MB | 1 |
| Al-Tammemi, AB | 1 |
| Mahmoud, NN | 1 |
| Jalouqa, S | 1 |
| Alrawashdeh, MN | 1 |
| Shanahan, JP | 1 |
| Moore, CM | 1 |
| Kampf, JW | 1 |
| Szymczak, NK | 1 |
| Guo, J | 1 |
| Wang, H | 5 |
| Luo, Y | 2 |
| An, H | 1 |
| Zhang, Z | 6 |
| Liu, G | 1 |
| Li, J | 15 |
| Metcalfe, GD | 1 |
| Smith, TW | 1 |
| Hippler, M | 1 |
| Ayala Izurieta, JE | 1 |
| Márquez, CO | 1 |
| García, VJ | 1 |
| Jara Santillán, CA | 1 |
| Sisti, JM | 1 |
| Pasqualotto, N | 1 |
| Van Wittenberghe, S | 1 |
| Delegido, J | 1 |
| Kubo, Y | 1 |
| Kitagawa, Y | 1 |
| Miyazaki, T | 1 |
| Sohda, M | 1 |
| Yamaji, T | 1 |
| Sakai, M | 1 |
| Saeki, H | 1 |
| Nemoto, K | 1 |
| Oyama, T | 2 |
| Muto, M | 1 |
| Takeuchi, H | 1 |
| Toh, Y | 1 |
| Matsubara, H | 1 |
| Mano, M | 1 |
| Kono, K | 1 |
| Kato, K | 3 |
| Yoshida, M | 1 |
| Kawakubo, H | 1 |
| Booka, E | 1 |
| Yamatsuji, T | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Ishikawa, H | 1 |
| Ishihara, R | 1 |
| Tsushima, T | 1 |
| Kawachi, H | 1 |
| Kojima, T | 1 |
| Kuribayashi, S | 1 |
| Makino, T | 1 |
| Matsuda, S | 1 |
| Doki, Y | 1 |
| Ma, P | 1 |
| Tang, X | 1 |
| Zhang, L | 7 |
| Wang, X | 11 |
| Wang, W | 7 |
| Zhang, X | 10 |
| Wang, S | 3 |
| Zhou, N | 1 |
| Dodd, J | 1 |
| Jordan, R | 1 |
| Makhlina, M | 1 |
| Pesco Koplowitz, L | 1 |
| Koplowitz, B | 1 |
| Barnett, K | 1 |
| Yang, WH | 1 |
| Spana, C | 1 |
| Buchanan, SW | 1 |
| Mafa-Attoye, T | 1 |
| Dunfield, K | 1 |
| Thevathasan, NV | 1 |
| Isaac, ME | 1 |
| Wu, X | 5 |
| Huang, JW | 2 |
| Su, BK | 1 |
| Yuan, L | 1 |
| Zheng, WQ | 1 |
| Zhang, H | 6 |
| Zheng, YX | 1 |
| Zhu, W | 1 |
| Chou, PT | 1 |
| Manso, AP | 1 |
| De Morais, DC | 1 |
| Yamamoto, K | 1 |
| Owen, G | 1 |
| de Carvalho, RM | 1 |
| Palma-Dibb, RG | 1 |
| Brown, JC | 1 |
| Yang, S | 3 |
| Mire, EF | 1 |
| Miele, L | 1 |
| Ochoa, A | 1 |
| Zabaleta, J | 1 |
| Katzmarzyk, PT | 1 |
| Moi, CT | 1 |
| Bhowmick, S | 1 |
| Qureshi, M | 1 |
| Wang, K | 2 |
| Feng, B | 1 |
| Yang, Y | 4 |
| Chen, Y | 3 |
| Wang, Y | 15 |
| Yang, L | 1 |
| Jiang, K | 1 |
| James, TD | 1 |
| Chaturvedi, V | 1 |
| Postiglione, WM | 1 |
| Chakraborty, RD | 1 |
| Yu, B | 3 |
| Tabiś, W | 1 |
| Hameed, S | 1 |
| Biniskos, N | 1 |
| Jacobson, A | 1 |
| Zhou, H | 3 |
| Greven, M | 1 |
| Ferry, VE | 1 |
| Leighton, C | 1 |
| Wu, F | 2 |
| Lei, H | 2 |
| Chen, G | 2 |
| Chen, C | 3 |
| Song, Y | 2 |
| Cao, Z | 1 |
| Zhang, C | 5 |
| Zhou, J | 1 |
| Lu, Y | 2 |
| Pappone, C | 1 |
| Santinelli, V | 1 |
| Mecarocci, V | 1 |
| Tondi, L | 1 |
| Ciconte, G | 1 |
| Manguso, F | 1 |
| Sturla, F | 1 |
| Vicedomini, G | 1 |
| Micaglio, E | 1 |
| Anastasia, L | 1 |
| Pica, S | 1 |
| Camporeale, A | 1 |
| Lombardi, M | 1 |
| Shieh, PB | 1 |
| Elfring, G | 1 |
| Trifillis, P | 1 |
| Santos, C | 1 |
| Peltz, SW | 1 |
| Parsons, JA | 1 |
| Apkon, S | 1 |
| Darras, BT | 1 |
| Campbell, C | 1 |
| McDonald, CM | 1 |
| Galaviz, KI | 1 |
| Shah, NS | 1 |
| Gutierrez, M | 1 |
| Collins, LF | 1 |
| Lahiri, CD | 1 |
| Moran, CA | 1 |
| Szabo, B | 1 |
| Sumitani, J | 1 |
| Rhodes, J | 1 |
| Marconi, VC | 1 |
| Nguyen, ML | 1 |
| Cantos, VD | 1 |
| Armstrong, WS | 1 |
| Colasanti, JA | 1 |
| Mao, X | 1 |
| Chen, H | 2 |
| Lin, AZ | 1 |
| Kim, S | 1 |
| Burczynski, ME | 1 |
| Na, E | 1 |
| Halasz, G | 1 |
| Sleeman, MW | 1 |
| Murphy, AJ | 1 |
| Okamoto, H | 1 |
| Cheng, X | 2 |
| Macedo de Oliveira, M | 1 |
| Monnet-Aimard, A | 1 |
| Bosoi, CR | 5 |
| Tremblay, M | 6 |
| Rose, CF | 7 |
| Soria, LR | 2 |
| Makris, G | 3 |
| D'Alessio, AM | 1 |
| De Angelis, A | 2 |
| Boffa, I | 1 |
| Pravata, VM | 1 |
| Rüfenacht, V | 1 |
| Attanasio, S | 2 |
| Nusco, E | 1 |
| Arena, P | 1 |
| Ferenbach, AT | 1 |
| Paris, D | 1 |
| Cuomo, P | 1 |
| Motta, A | 1 |
| Nitzahn, M | 3 |
| Lipshutz, GS | 6 |
| Martínez-Pizarro, A | 1 |
| Richard, E | 1 |
| Desviat, LR | 1 |
| Häberle, J | 5 |
| van Aalten, DMF | 1 |
| Brunetti-Pierri, N | 2 |
| Belanger, AJ | 1 |
| Gefteas, E | 1 |
| Przybylska, M | 1 |
| Geller, S | 1 |
| Anarat-Cappillino, G | 1 |
| Kloss, A | 1 |
| Yew, NS | 1 |
| Claeys, W | 1 |
| Van Hoecke, L | 1 |
| Geerts, A | 1 |
| Van Vlierberghe, H | 1 |
| Lefere, S | 1 |
| Van Imschoot, G | 1 |
| Van Wonterghem, E | 1 |
| Ghesquière, B | 1 |
| Vandenbroucke, RE | 1 |
| Van Steenkiste, C | 1 |
| Qutob, HMH | 1 |
| Saad, RA | 1 |
| Bali, H | 1 |
| Osailan, A | 1 |
| Jaber, J | 1 |
| Alzahrani, E | 1 |
| Alyami, J | 1 |
| Elsayed, H | 1 |
| Alserihi, R | 1 |
| Shaikhomar, OA | 1 |
| Divya, KM | 1 |
| Savitha, DP | 1 |
| Krishna, GA | 1 |
| Dhanya, TM | 1 |
| Mohanan, PV | 1 |
| Shah, SF | 1 |
| Jafry, AT | 1 |
| Hussain, G | 1 |
| Kazim, AH | 1 |
| Ali, M | 1 |
| Rivani, E | 1 |
| Endraswari, PD | 1 |
| Widodo, ADW | 1 |
| Khalil, MR | 1 |
| Guldberg, R | 1 |
| Nørgård, BM | 1 |
| Uldbjerg, N | 1 |
| Wehberg, S | 1 |
| Fowobaje, KR | 1 |
| Mashood, LO | 1 |
| Ekholuenetale, M | 1 |
| Ibidoja, OJ | 1 |
| Romagnoli, A | 1 |
| D'Agostino, M | 1 |
| Pavoni, E | 1 |
| Ardiccioni, C | 1 |
| Motta, S | 1 |
| Crippa, P | 1 |
| Biagetti, G | 1 |
| Notarstefano, V | 1 |
| Rexha, J | 1 |
| Perta, N | 1 |
| Barocci, S | 1 |
| Costabile, BK | 1 |
| Colasurdo, G | 1 |
| Caucci, S | 1 |
| Mencarelli, D | 1 |
| Turchetti, C | 1 |
| Farina, M | 1 |
| Pierantoni, L | 1 |
| La Teana, A | 1 |
| Al Hadi, R | 1 |
| Cicconardi, F | 1 |
| Chinappi, M | 1 |
| Trucchi, E | 1 |
| Mancia, F | 1 |
| Menzo, S | 1 |
| Morozzo Della Rocca, B | 1 |
| D'Annessa, I | 1 |
| Di Marino, D | 1 |
| Choya, A | 1 |
| de Rivas, B | 1 |
| Gutiérrez-Ortiz, JI | 1 |
| López-Fonseca, R | 1 |
| Xu, S | 1 |
| Cheng, B | 1 |
| Huang, Z | 3 |
| Liu, T | 3 |
| Li, Y | 11 |
| Jiang, L | 2 |
| Guo, W | 2 |
| Xiong, J | 1 |
| Amirazodi, M | 1 |
| Daryanoosh, F | 1 |
| Mehrabi, A | 1 |
| Gaeini, A | 1 |
| Koushkie Jahromi, M | 1 |
| Salesi, M | 1 |
| Zarifkar, AH | 1 |
| Studeny, P | 1 |
| Netukova, M | 1 |
| Nemcokova, M | 1 |
| Klimesova, YM | 1 |
| Krizova, D | 1 |
| Kang, H | 1 |
| Tao, Y | 1 |
| Zhang, Q | 6 |
| Sha, D | 1 |
| Yao, J | 1 |
| Gao, Y | 5 |
| Liu, J | 8 |
| Ji, L | 1 |
| Shi, P | 1 |
| Shi, C | 1 |
| Wu, YL | 1 |
| Wright, AI | 1 |
| M El-Metwaly, N | 1 |
| A Katouah, H | 1 |
| El-Desouky, MG | 1 |
| El-Bindary, AA | 1 |
| El-Bindary, MA | 1 |
| Kostakis, ID | 1 |
| Raptis, DA | 1 |
| Davidson, BR | 1 |
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| Sharma, D | 1 |
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| Pollok, JM | 1 |
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| Ayorech, Z | 1 |
| Tesli, M | 1 |
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| Reichborn-Kjennerud, T | 1 |
| Andreassen, OA | 1 |
| Magnus, P | 1 |
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| Johansson, S | 1 |
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| Davey Smith, G | 1 |
| Havdahl, A | 1 |
| Howe, LD | 1 |
| Davies, NM | 1 |
| Amrillah, T | 1 |
| Prasetio, A | 1 |
| Supandi, AR | 1 |
| Sidiq, DH | 1 |
| Putra, FS | 1 |
| Nugroho, MA | 1 |
| Salsabilla, Z | 1 |
| Azmi, R | 1 |
| Grammatikopoulos, P | 1 |
| Bouloumis, T | 1 |
| Steinhauer, S | 1 |
| Mironov, VS | 2 |
| Bazhenova, TA | 2 |
| Manakin, YV | 2 |
| Yagubskii, EB | 2 |
| Yakushev, IA | 1 |
| Gilmutdinov, IF | 1 |
| Simonov, SV | 1 |
| Lan, K | 1 |
| Yang, H | 1 |
| Zheng, J | 2 |
| Hu, H | 2 |
| Zhu, T | 1 |
| Zou, X | 1 |
| Hu, B | 2 |
| Liu, H | 5 |
| Olokede, O | 1 |
| Wu, H | 1 |
| Holtzapple, M | 1 |
| Gungor, O | 1 |
| Kose, M | 1 |
| Ghaemi, R | 1 |
| Acker, M | 1 |
| Stosic, A | 1 |
| Jacobs, R | 1 |
| Selvaganapathy, PR | 1 |
| Ludwig, N | 1 |
| Yerneni, SS | 1 |
| Azambuja, JH | 1 |
| Pietrowska, M | 1 |
| Widłak, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does a Flashlight Used to Detect Pet Biological Fluids on Human Skin and Other Surfaces Increase Gas Phase Nitric Oxide Levels?[NCT04903535] | 100 participants (Anticipated) | Interventional | 2021-05-10 | Enrolling by invitation | |||
| The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity[NCT02896309] | 45 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for ammonium hydroxide and Disease Models, Animal
| Article | Year |
|---|---|
Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes | 2021 |
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The Pharmabiotic Approach to Treat Hyperammonemia.
Topics: Ammonia; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease M | 2018 |
Comprehensive characterization of ureagenesis in the spf
Topics: Age Factors; Aging; Ammonia; Animals; Disease Models, Animal; Humans; Hyperammonemia; Liver; Male; M | 2019 |
Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications.
Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Disease Models, Animal; Glutamine; Hepatic Encephalop | 2013 |
Nitrogen chemistry and lung physiology.
Topics: Amines; Ammonia; Animals; Disease Models, Animal; Humans; Lung; Lung Diseases; Nitric Oxide; Nitroge | 2015 |
The Na-K-Cl Co-transporter in astrocyte swelling.
Topics: Ammonia; Animals; Astrocytes; Brain; Brain Edema; Cell Size; Disease Models, Animal; Hepatic Encepha | 2010 |
Animal models of hepatic encephalopathy and hyperammonemia.
Topics: Ammonia; Animals; Disease Models, Animal; Hepatic Encephalopathy; Humans | 1994 |
Sparse-fur (spf) mouse as a model of hyperammonemia: alterations in the neurotransmitter systems.
Topics: Ammonia; Animals; Chromosome Aberrations; Chromosome Disorders; Disease Models, Animal; Gene Express | 1997 |
Hepatic encephalopathy.
Topics: Ammonia; Animals; Disease Models, Animal; GABA-A Receptor Agonists; Hepatic Encephalopathy; Humans; | 2001 |
Experimental liver diseases.
Topics: Alkaloids; Ammonia; Animals; Bilirubin; Budd-Chiari Syndrome; Carbon Tetrachloride Poisoning; Cattle | 1975 |
The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands.
Topics: Ammonia; Animals; Disease Models, Animal; Flumazenil; Hepatic Encephalopathy; Humans; Ligands; Neuro | 1991 |
Ammonium transport in the kidney: new physiological concepts and their clinical implications.
Topics: Acidosis, Renal Tubular; Ammonia; Animals; Biological Transport, Active; Disease Models, Animal; Hum | 1991 |
Hepatic coma: present concepts of pathogenesis and therapy.
Topics: Adrenal Cortex Hormones; Amino Acids; Ammonia; Animals; Anti-Bacterial Agents; Biogenic Amines; Brai | 1972 |
4 trials available for ammonium hydroxide and Disease Models, Animal
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
An engineered
Topics: Ammonia; Animals; Arginine; Biosynthetic Pathways; Disease Models, Animal; Escherichia coli; Feces; | 2019 |
Ammonia impairs neutrophil phagocytic function in liver disease.
Topics: Amino Acids; Ammonia; Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Double-Blind | 2008 |
263 other studies available for ammonium hydroxide and Disease Models, Animal
| Article | Year |
|---|---|
Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model.
Topics: Ammonia; Animals; Disease Models, Animal; Glutaminase; Glutamine; Humans; Hyperammonemia; Liver; Mic | 2022 |
Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile-duct ligated rats.
Topics: Allopurinol; Ammonia; Animals; Bile; Disease Models, Animal; Female; Hepatic Encephalopathy; Hyperam | 2022 |
O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.
Topics: Acetylglucosamine; Ammonia; Animals; Biocatalysis; Carbamoyl-Phosphate Synthase (Ammonia); Disease M | 2022 |
Excretion of excess nitrogen and increased survival by loss of SLC6A19 in a mouse model of ornithine transcarbamylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Neutral; Ammonia; Animals; Disea | 2023 |
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
Topics: Ammonia; Animals; Bile Acids and Salts; Bile Ducts; Brain; Choline; Disease Models, Animal; Glutamin | 2022 |
Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system.
Topics: Adsorption; Ammonia; Animals; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Liv | 2023 |
Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury.
Topics: Acetaminophen; Ammonia; Animals; Cattle; Cell Survival; Chemical and Drug Induced Liver Injury; Chon | 2019 |
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
Topics: Ammonia; Animals; Arginase; Arginine; Codon; Disease Models, Animal; Glutamine; Hyperammonemia; Hype | 2019 |
BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats.
Topics: Ammonia; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Hepatic Encephalopathy; Inflamma | 2020 |
High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone.
Topics: Ammonia; Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Female; Glutamic | 2020 |
Split AAV-Mediated Gene Therapy Restores Ureagenesis in a Murine Model of Carbamoyl Phosphate Synthetase 1 Deficiency.
Topics: Ammonia; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency | 2020 |
An orally delivered microbial cocktail for the removal of nitrogenous metabolic waste in animal models of kidney failure.
Topics: Administration, Oral; Alginates; Ammonia; Animals; Bacteria; Capsules; Creatinine; Disease Models, A | 2020 |
Yan-Hou-Qing formula attenuates ammonia-induced acute pharyngitis in rats via inhibition of NF-κB and COX-2.
Topics: Ammonia; Animals; China; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Female; Mo | 2020 |
Effects of resveratrol on alterations in cerebrum energy metabolism caused by metabolites accumulated in type I citrullinemia in rats.
Topics: Ammonia; Animals; Cerebellum; Cerebral Cortex; Citrulline; Citrullinemia; Disease Models, Animal; Do | 2021 |
Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency.
Topics: Ammonia; Animals; Child, Preschool; Disease Models, Animal; Female; Gene Expression Regulation; Hepa | 2021 |
Bile-duct ligation renders the brain susceptible to hypotension-induced neuronal degeneration: Implications of ammonia.
Topics: Ammonia; Animals; Antigens, Nuclear; Anxiety; Apoptosis; Behavior, Animal; Bile Ducts; Caspase 3; Ce | 2021 |
Potassium deficiency decreases the capacity for urea synthesis and markedly increases ammonia in rats.
Topics: Ammonia; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Hyperammo | 2021 |
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.
Topics: Adult; Aged; Ammonia; Animals; Cells, Cultured; Child; Disease Models, Animal; Female; Gene Editing; | 2021 |
Sirtuin-3 activation by honokiol restores mitochondrial dysfunction in the hippocampus of the hepatic encephalopathy rat model of ammonia neurotoxicity.
Topics: Ammonia; Animals; Disease Models, Animal; Hepatic Encephalopathy; Hippocampus; Male; Mitochondria; N | 2021 |
NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target.
Topics: Ammonia; Animals; Bacterial Proteins; Caenorhabditis elegans; Cell Line; Disease Models, Animal; Dro | 2021 |
Oral administration of trace element magnesium significantly improving the cognition and locomotion in hepatic encephalopathy rats.
Topics: Administration, Oral; Ammonia; Animals; Brain; Cognition; Dietary Supplements; Disease Models, Anima | 2017 |
Ameliorative effects of rutin on hepatic encephalopathy-induced by thioacetamide or gamma irradiation.
Topics: Acetylcholinesterase; Administration, Oral; Alanine Transaminase; Ammonia; Animals; Aspartate Aminot | 2017 |
Hyperammonemia compromises glutamate metabolism and reduces BDNF in the rat hippocampus.
Topics: Ammonia; Animals; Animals, Newborn; Astrocytes; Brain-Derived Neurotrophic Factor; Cells, Cultured; | 2017 |
Artificial liver support in pigs with acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Cell Nucleus; Creatinine; D | 2017 |
Lactulose decreases neuronal activation and attenuates motor behavioral deficits in hyperammonemic rats.
Topics: Ammonia; Animals; Aquaporin 4; Aspartate Aminotransferases; Behavior, Animal; Bilirubin; Creatinine; | 2017 |
Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats.
Topics: Alanine Transaminase; Ammonia; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Bip | 2017 |
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
Topics: Ammonia; Animals; Citrus; Cytokines; Disease Models, Animal; HEK293 Cells; Humans; I-kappa B Kinase; | 2017 |
Novel D-galactosamine-induced cynomolgus monkey model of acute liver failure.
Topics: Ammonia; Animals; Disease Models, Animal; Galactosamine; Intracranial Pressure; Liver Failure, Acute | 2017 |
Antitussive and expectorant activities of licorice and its major compounds.
Topics: Administration, Oral; Ammonia; Animals; Antitussive Agents; Cough; Disease Models, Animal; Dose-Resp | 2018 |
Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis.
Topics: Ammonia; Animals; Biopsy; Disease Models, Animal; Disease Progression; Fibrosis; Hepatic Stellate Ce | 2018 |
Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.
Topics: Ammonia; Animals; Antibodies; Anticoagulants; Blood Vessels; Cytokines; Disease Models, Animal; Fibr | 2018 |
Ammonia role in glial dysfunction in methylmalonic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Ammonium Chloride; Animals; Behavior, Animal; Brain; | 2018 |
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Topics: Ammonia; Analysis of Variance; Animals; Brain; Cation Transport Proteins; Disease Models, Animal; Do | 2018 |
Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure.
Topics: Ammonia; Animals; Bile Acids and Salts; Cell Line; Disease Models, Animal; End Stage Liver Disease; | 2018 |
Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy.
Topics: Ammonia; Animals; Aquaporin 4; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Emodi | 2018 |
Progressive resistance training prevents loss of muscle mass and strength in bile duct-ligated rats.
Topics: Ammonia; Animals; Bile Ducts; Body Composition; Disease Models, Animal; Hepatic Encephalopathy; Hype | 2019 |
Hepatic glutamine synthetase augmentation enhances ammonia detoxification.
Topics: Ammonia; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency | 2019 |
Taurine transporter (TauT) deficiency impairs ammonia detoxification in mouse liver.
Topics: Ammonia; Animals; Deficiency Diseases; Disease Models, Animal; GABA Plasma Membrane Transport Protei | 2019 |
Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.
Topics: Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Citrulline; Citrullinemia; Disease | 2019 |
In-solution behavior and protective potential of asparagine synthetase A from Trypanosoma cruzi.
Topics: Ammonia; Animals; Asparagine; Aspartate-Ammonia Ligase; Chagas Disease; Chromatography, Liquid; Circ | 2019 |
Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease.
Topics: Ammonia; Animals; Cells, Cultured; Disease Models, Animal; Disease Progression; Female; Humans; Live | 2020 |
Evaluation of the Hepa Wash® treatment in pigs with acute liver failure.
Topics: Ammonia; Animals; Blood Pressure; Cardiac Output; Creatinine; Dialysis; Disease Models, Animal; Fema | 2013 |
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure.
Topics: Ammonia; Animals; Azoxymethane; Blood-Brain Barrier; Cytokines; Disease Models, Animal; Hepatic Ence | 2014 |
Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1.
Topics: Ammonia; Animals; Argininosuccinate Synthase; Citrulline; Citrullinemia; Dependovirus; Disease Model | 2013 |
Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy.
Topics: Acute Disease; Ammonia; Animals; Astrocytes; Brain Edema; Cell Communication; Cells, Cultured; Cereb | 2014 |
Knockdown of asparagine synthetase A renders Trypanosoma brucei auxotrophic to asparagine.
Topics: Adenosine Triphosphate; Ammonia; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Aspart | 2013 |
Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats.
Topics: Ammonia; Animals; Bile Ducts; Disease Models, Animal; End Stage Liver Disease; Glutamate-Ammonia Lig | 2014 |
Differential up-regulation of ammonia detoxifying enzymes in cerebral cortex, cerebellum, hippocampus, striatum and liver in hyperammonemia.
Topics: Alanine Transaminase; Ammonia; AMP Deaminase; Animals; Aspartate Aminotransferases; Brain; Disease M | 2014 |
Imaging of cardiac and renal perfusion in a rat model with 13N-NH 3 micro-PET.
Topics: Ammonia; Animals; Coronary Circulation; Disease Models, Animal; Male; Myocardial Infarction; Myocard | 2015 |
L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway.
Topics: Ammonia; Animals; Biomarkers; Brain; Disease Models, Animal; Female; Glycine; Hyperammonemia; Kidney | 2014 |
Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.
Topics: Ammonia; Animals; Arginase; Dependovirus; Disease Models, Animal; Genetic Therapy; Hyperammonemia; H | 2015 |
Impaired expression of key molecules of ammoniagenesis underlies renal acidosis in a rat model of chronic kidney disease.
Topics: Acidosis; Amino Acid Transport Systems, Neutral; Ammonia; Animals; Bicarbonates; Creatinine; Disease | 2015 |
pH-sensitive microemulsion-based gels for removal of colonic ammonia: a novel preventative oral preparation for hepatic encephalopathy in rats.
Topics: Alanine Transaminase; Ammonia; Animals; Bilirubin; Body Weight; Disease Models, Animal; Electroencep | 2015 |
Multiparametric molecular imaging provides mechanistic insights into sympathetic innervation impairment in the viable infarct border zone.
Topics: Ammonia; Animals; Arrhythmias, Cardiac; Carbon Radioisotopes; Catecholamines; Disease Models, Animal | 2015 |
Use of [18F]FDG Positron Emission Tomography to Monitor the Development of Cardiac Allograft Rejection.
Topics: Allografts; Ammonia; Animals; Diet, Carbohydrate-Restricted; Disease Models, Animal; Fluorodeoxygluc | 2015 |
Behavioral alterations and Fos protein immunoreactivity in brain regions of bile duct-ligated cirrhotic rats.
Topics: Ammonia; Animals; Anxiety; Behavior, Animal; Bile Ducts; Brain Chemistry; Disease Models, Animal; Im | 2015 |
Integrated compensatory network is activated in the absence of NCC phosphorylation.
Topics: Amiloride; Ammonia; Animals; Biological Transport; Blood Pressure; Carbonic Anhydrases; Chlorides; D | 2015 |
D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure?
Topics: Acute Kidney Injury; Alanine Transaminase; Albumins; Ammonia; Animals; Aspartate Aminotransferases; | 2015 |
Engineering the gut microbiota to treat hyperammonemia.
Topics: Ammonia; Animals; Bacteria; Bacterial Proteins; Bioengineering; Biological Therapy; Chemical and Dru | 2015 |
Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara.
Topics: Acetates; Ammonia; Animals; Anti-Inflammatory Agents; Antitussive Agents; Cough; Disease Models, Ani | 2016 |
The Influence of Finasteride on Mean and Relative Spectral Density of EEG Bands in Rat Model of Thioacetamide-Induced Hepatic Encephalopathy.
Topics: 5-alpha Reductase Inhibitors; Ammonia; Animals; Brain; Brain Waves; Central Nervous System Agents; D | 2016 |
Peripheral ammonia and blood brain barrier structure and function after methamphetamine.
Topics: Ammonia; Animals; Blood-Brain Barrier; Capillaries; Capillary Permeability; Central Nervous System S | 2016 |
Development of an experimental rat model of hyperammonemic encephalopathy and evaluation of the effects of rifaximin.
Topics: Ammonia; Animals; Behavior, Animal; Brain; Coma; Disease Models, Animal; Hepatic Encephalopathy; Hyp | 2016 |
Guanosine Exerts Neuroprotective Effect in an Experimental Model of Acute Ammonia Intoxication.
Topics: Ammonia; Animals; Biomarkers; Brain; Coma; Disease Models, Animal; Electroencephalography; Guanosine | 2017 |
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Topics: Action Potentials; Ammonia; Animals; Animals, Newborn; Arginase; Disease Models, Animal; Genetic The | 2016 |
Colonic mucosal N-methyl-D-aspartate receptor mediated visceral hypersensitivity in a mouse model of irritable bowel syndrome.
Topics: Ammonia; Animals; Colon; Dilatation; Disease Models, Animal; Feces; Glutamic Acid; Intestinal Mucosa | 2016 |
Novel Combination of Prebiotics Galacto-Oligosaccharides and Inulin-Inhibited Aberrant Crypt Foci Formation and Biomarkers of Colon Cancer in Wistar Rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Ammonia; Animals; Anticarcinogenic Agents; Bacterial Pro | 2016 |
Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Biomarkers; Brain; Carnitine; Dietary Protei | 2016 |
Ureaplasma urealyticum Causes Hyperammonemia in an Experimental Immunocompromised Murine Model.
Topics: Ammonia; Animals; Disease Models, Animal; Hyperammonemia; Immunocompromised Host; Immunosuppressive | 2016 |
NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility.
Topics: Ammonia; Animals; Animals, Newborn; Bumetanide; Cell Count; Cerebral Cortex; Disease Models, Animal; | 2017 |
The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis.
Topics: Ammonia; Animals; Base Composition; Bile Ducts; Disease Models, Animal; Eating; Hepatic Encephalopat | 2017 |
Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease.
Topics: Ammonia; Analysis of Variance; Animals; Bile Ducts; Biomarkers; Blotting, Western; Cerebral Cortex; | 2017 |
Cortical Synaptic Transmission and Plasticity in Acute Liver Failure Are Decreased by Presynaptic Events.
Topics: Ammonia; Animals; Cerebral Cortex; Cytokines; Disease Models, Animal; Liver Failure, Acute; Male; Mi | 2018 |
Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis.
Topics: Ammonia; Analysis of Variance; Animals; Autophagy; Disease Models, Animal; Homeostasis; Hyperammonem | 2017 |
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction.
Topics: Ammonia; Animals; Catecholamines; Disease Models, Animal; Epinephrine; Heart; Magnetic Resonance Ima | 2008 |
Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain.
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Disease Progression; Dizocilpine Maleate; Excitator | 2008 |
Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure.
Topics: Adult; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetra | 2009 |
[Race of experimental animals and development of renal failure in animal model of hepatorenal syndrome].
Topics: Alanine Transaminase; Ammonia; Animals; Bilirubin; Disease Models, Animal; Galactosamine; Hepatocyte | 2008 |
Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents.
Topics: Acute Disease; Alanine; Ammonia; Animals; Carbon Tetrachloride; Chronic Disease; Disease Models, Ani | 2008 |
Plasma exchange-based plasma recycling dialysis system as an artificial liver support.
Topics: Ammonia; Animals; Anion Exchange Resins; Bile Acids and Salts; Bilirubin; Charcoal; Dialysis; Diseas | 2008 |
Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia.
Topics: Ammonia; Animals; Astrocytes; Brain; Carbon Radioisotopes; Cells, Cultured; Cholestasis; Citric Acid | 2009 |
Expanding the versatility of cardiac PET/CT: feasibility of delayed contrast enhancement CT for infarct detection in a porcine model.
Topics: Ammonia; Animals; Contrast Media; Disease Models, Animal; Myocardial Infarction; Myocardial Perfusio | 2009 |
Direct evidence for central proinflammatory mechanisms in rats with experimental acute liver failure: protective effect of hypothermia.
Topics: Ammonia; Animals; Brain Edema; CD11b Antigen; Cytokines; Disease Models, Animal; Gene Expression; He | 2009 |
Y-box binding protein-1 down-regulates expression of carbamoyl phosphate synthetase-I by suppressing CCAAT enhancer-binding protein-alpha function in mice.
Topics: Age Factors; Ammonia; Animals; Animals, Newborn; Base Sequence; Carbamoyl-Phosphate Synthase (Ammoni | 2009 |
Technical breakthroughs in the wearable artificial kidney (WAK).
Topics: Ammonia; Animals; beta 2-Microglobulin; Biomarkers; Charcoal; Creatinine; Dialysis Solutions; Diseas | 2009 |
AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis.
Topics: Acute Disease; Adenine Nucleotides; Adenosine Deaminase; Ammonia; AMP Deaminase; Animals; Brain; Car | 2010 |
Glutamine synthetase deficiency in murine astrocytes results in neonatal death.
Topics: Adenylate Kinase; Amino Acids; Ammonia; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; | 2010 |
Portacaval anastomosis-induced hyperammonemia does not lead to oxidative stress.
Topics: Aldehydes; Ammonia; Animals; Biomarkers; Blotting, Western; Brain; Disease Models, Animal; Frontal L | 2010 |
Effect of intercalated cell-specific Rh C glycoprotein deletion on basal and metabolic acidosis-stimulated renal ammonia excretion.
Topics: Acidosis; Adaptation, Physiological; Ammonia; Animals; Bicarbonates; Cation Transport Proteins; Dise | 2010 |
A new experimental model for acute hepatic failure in rats.
Topics: Ammonia; Animals; Bilirubin; Creatine; Disease Models, Animal; Hepatectomy; Hepatic Encephalopathy; | 2010 |
Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle.
Topics: Acute Disease; Amino Acids, Branched-Chain; Ammonia; Animals; Disease Models, Animal; Extracellular | 2011 |
New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA.
Topics: Acyl Coenzyme A; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Anticonvulsants; Citrulline; Dise | 2011 |
Influence of rutin on biochemical alterations in hyperammonemia in rats.
Topics: Administration, Oral; Ammonia; Animals; Antioxidants; Body Weight; Brain; Disease Models, Animal; Hy | 2012 |
Microglia activation in hepatic encephalopathy in rats and humans.
Topics: Ammonia; Animals; Astrocytes; Autopsy; Calcium-Binding Proteins; Cell Movement; Cells, Cultured; Cer | 2011 |
Neuromonitoring in a porcine model of acute hepatic failure.
Topics: Ammonia; Animals; Brain Edema; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Evok | 2011 |
p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.
Topics: Ammonia; Animals; Blotting, Western; Cerebellum; Cerebral Cortex; Cognition; Disease Models, Animal; | 2011 |
Development of a porcine model of post-hepatectomy liver failure.
Topics: Ammonia; Animals; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Female; Hepatecto | 2011 |
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.
Topics: Amino Acids; Ammonia; Animals; Brain; Disease Models, Animal; Evoked Potentials, Motor; Glutamine; H | 2012 |
Metabolomic analysis reveals hepatic metabolite perturbations in citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mice, a model of human citrin deficiency.
Topics: Ammonia; Animals; Calcium-Binding Proteins; Citric Acid Cycle; Disease Models, Animal; Electrophores | 2011 |
β-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; beta Catenin; Disease Models, A | 2012 |
Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models.
Topics: Ammonia; Animals; Cerebellum; Cognition; Disease Models, Animal; Hepatic Encephalopathy; Humans; Hyp | 2012 |
Ammonia-induced brain swelling and neurotoxicity in an organotypic slice model.
Topics: Ammonia; Animals; Animals, Newborn; Brain; Brain Edema; Disease Models, Animal; Hepatic Encephalopat | 2011 |
Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice.
Topics: Ammonia; Animals; Antitussive Agents; Chlorogenic Acid; Cough; Disease Models, Animal; Drug Contamin | 2012 |
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure.
Topics: Ammonia; Animals; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; End Stage Liver Disease; | 2012 |
Artificial liver support system reduces intracranial pressure more effectively than bioartificial system: an experimental study.
Topics: Ammonia; Animals; Bilirubin; Biomarkers; Cerebrovascular Circulation; Disease Models, Animal; Equipm | 2012 |
Long-term activation of semicarbazide-sensitive amine oxidase lowers circulating levels of uric acid in diabetic conditions.
Topics: Amine Oxidase (Copper-Containing); Ammonia; Animals; Benzylamines; Blood Glucose; Cell Adhesion Mole | 2012 |
Chronic postnatal ornithine administration to rats provokes learning deficit in the open field task.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Animals, Newborn; Avoidance Learning; Behavi | 2012 |
Peripheral ammonia as a mediator of methamphetamine neurotoxicity.
Topics: Alanine Transaminase; Ammonia; Analysis of Variance; Animals; Aspartate Aminotransferases; Benzodiaz | 2012 |
Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-bioartificial liver.
Topics: Amino Acids; Ammonia; Animals; Apolipoprotein A-I; Cell Line, Tumor; Cytochrome P-450 CYP3A; Disease | 2013 |
Ammonia aggravates stress-induced gastric mucosal oxidative injury through the cancellation of cytoprotective heat shock protein 70.
Topics: Ammonia; Animals; Disease Models, Animal; Electroshock; Emotions; Free Radicals; Gastric Mucosa; Gen | 2002 |
The development of a new bioartificial liver and its application in 12 acute liver failure patients.
Topics: Adolescent; Adult; Ammonia; Animals; Bilirubin; Disease Models, Animal; Equipment Design; Female; He | 2003 |
The relationship between the level of thirteen different substances and enzymes in blood and peritoneal fluid and the duration of mechanical intestinal obstruction: an experimental study on rats.
Topics: Ammonia; Animals; Ascitic Fluid; Blood Chemical Analysis; Disease Models, Animal; Fructose-Bisphosph | 2003 |
Tochu (Eucommia ulmoides) leaf extract prevents ammonia and vitamin C deficiency induced gastric mucosal injury.
Topics: Ammonia; Animals; Anti-Ulcer Agents; Antioxidants; Ascorbic Acid; Ascorbic Acid Deficiency; Cell Div | 2003 |
Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia.
Topics: Amino Acids; Ammonia; Animals; Argininosuccinate Synthase; Aspartic Acid; Base Sequence; Citrullinem | 2004 |
Rabbit retinal organ culture as an in-vitro model of hepatic retinopathy.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glial Fibrillary A | 2004 |
Efficacy of immunoadsorbent devices for maintaining hepatic function in ex vivo direct xenogenic hemoperfusion.
Topics: Alanine Transaminase; Ammonia; Animals; Bioreactors; Disease Models, Animal; Dogs; Graft Rejection; | 2004 |
Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori.
Topics: Acids; Adaptation, Physiological; Amidohydrolases; Ammonia; Animals; Bacterial Proteins; Buffers; Di | 2004 |
Chronic gastritis rat model and role of inducing factors.
Topics: Alcohols; Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Chronic Disease; Deoxy | 2004 |
[Description of an experimental model of hepatorenal syndrome in Wistar rats].
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Anim | 2004 |
Hyperammonaemia reduces intracellular 22Na (sodium) ion and extracellular 86Rb ion concentrations in the blood-brain barrier of the rat.
Topics: Ammonia; Animals; Blood-Brain Barrier; Carbon Radioisotopes; Choroid Plexus; Diffusion; Disease Mode | 2005 |
An experimental animal model of fulminant hepatic failure in pigs.
Topics: Acidosis; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Blood Urea Nitrog | 2005 |
Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study.
Topics: Albumins; Ammonia; Animals; Brain Edema; Cerebrovascular Circulation; Disease Models, Animal; Female | 2006 |
Functional evaluation of a new bioartificial liver system in vitro and in vitro.
Topics: Alanine Transaminase; Albumins; Ammonia; Animals; Bilirubin; Bioreactors; Cell Survival; Cells, Cult | 2006 |
Citrate therapy in Dent's disease.
Topics: Acidosis; Ammonia; Animals; Chronic Disease; Citrates; Disease Models, Animal; Humans; Hydrogen-Ion | 2006 |
Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis.
Topics: Ammonia; Animals; Basal Ganglia; Cerebral Cortex; Disease Models, Animal; Duodenum; Glutaminase; Hep | 2006 |
A latex-induced allergic airway inflammation model in mice.
Topics: Allergens; Ammonia; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Immu | 2006 |
Protective effects of Gingko biloba on thioacetamide-induced fulminant hepatic failure in rats.
Topics: Acetylcysteine; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Chem | 2006 |
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C | 2007 |
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Anim | 2008 |
Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
Topics: Ammonia; Animals; Brain Chemistry; Disease Models, Animal; Extracellular Space; Female; Glutamic Aci | 2007 |
Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.
Topics: Alanine; Ammonia; Animals; Arginine; Citrulline; Disease Models, Animal; Female; Glycine; Injections | 2007 |
Cerebral blood flow autoregulation in experimental liver failure.
Topics: Ammonia; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Anim | 2008 |
Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo.
Topics: Amino Acids; Ammonia; Animals; Aquaporin 4; Astrocytes; Connexin 43; Diet, Reducing; Disease Models, | 2008 |
Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis.
Topics: Acidosis; Ammonia; Ammonium Chloride; Angiotensin II; Animals; Disease Models, Animal; Kidney Cortex | 2008 |
[Pathogenesis of hepatic encephalopathy--studies in the rabbit model of acute liver failure].
Topics: Ammonia; Animals; Arousal; Brain; Disease Models, Animal; Electroencephalography; Evoked Potentials, | 1984 |
Altered auditory brainstem evoked responses in the ferret model for Reye's syndrome.
Topics: Ammonia; Animals; Aspirin; Audiometry; Audiometry, Evoked Response; Brain Stem; Disease Models, Anim | 1984 |
Large-pore hemodialytic procedures in pigs with ischemic hepatic necrosis; a randomized study.
Topics: Ammonia; Animals; Blood; Disease Models, Animal; Electroencephalography; Hepatic Encephalopathy; Isc | 1984 |
Free fatty acids in an animal model of Reye's syndrome.
Topics: Ammonia; Animals; Aspirin; Carnivora; Diet; Disease Models, Animal; Fatty Acids, Nonesterified; Ferr | 1983 |
Fatty liver and kidney syndrome in chickens as an animal model for Reye's syndrome.
Topics: Ammonia; Animals; Blood Glucose; Carbon-Carbon Ligases; Carboxy-Lyases; Chickens; Disease Models, An | 1983 |
Increased tryptophan uptake into the brain in hyperammonemia.
Topics: Amino Acids; Ammonia; Animals; Brain; Brain Stem; Disease Models, Animal; Indoles; Male; Probenecid; | 1983 |
Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins.
Topics: Ammonia; Animals; Caprylates; Disease Models, Animal; Disulfides; Evoked Potentials, Visual; Galacto | 1984 |
Hepatocyte heterogeneity in ammonia metabolism: impairment of glutamine synthesis in CCl4 induced liver cell necrosis with no effect on urea synthesis.
Topics: Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Mo | 1984 |
[Hyperammonemia and decrease of growth and nocturnal locomotion in rats with portal stricture and uremia].
Topics: Ammonia; Animals; Constriction, Pathologic; Disease Models, Animal; Growth Disorders; Male; Motor Ac | 1984 |
Hypoglycin toxicity: studies of ammonia metabolism.
Topics: Ammonia; Animals; Citrulline; Cyclopropanes; Disease Models, Animal; Humans; Hypoglycins; Liver; Nit | 1983 |
The brain in experimental portal-systemic encephalopathy. I. Morphological changes in three animal models.
Topics: Ammonia; Animals; Astrocytes; Brain; Carbon Tetrachloride Poisoning; Cation Exchange Resins; Cerebel | 1983 |
The brain in experimental portal-systemic encephalopathy. II. Water and electrolyte changes.
Topics: Ammonia; Animals; Blood Proteins; Body Water; Brain; Cation Exchange Resins; Chlorides; Disease Mode | 1983 |
The sparse fur mouse: an animal model for a human inborn error of metabolism of the urea cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Carbamyl Phosphate; Disease Models, Animal; | 1983 |
Interactions of aspirin and other potential etiologic factors in an animal model of Reye syndrome.
Topics: Ammonia; Animals; Arginine; Aspartate Aminotransferases; Aspirin; Diet; Disease Models, Animal; Ferr | 1982 |
Serum enzyme alterations in arginine-deficient, influenza-infected ferrets: a potential animal model of Reye's syndrome.
Topics: Ammonia; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Ferrets; Humans; In | 1982 |
Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy.
Topics: Ammonia; Animals; Brain; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatic Enc | 1982 |
[Hepatic coma - experimental study with swine (part 1)].
Topics: Acetamides; Ammonia; Animals; Creatinine; Disease Models, Animal; Electrolytes; Enzymes; Female; Hep | 1981 |
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amino Acids; Ammonia; Animals; Biogenic Monoamines; B | 1995 |
[The effect of lactitol (NS-4) on the concentrations of ammonia and amino acids in blood and cerebrospinal fluid in Eck fistula (portacaval-shunted) dogs].
Topics: Amino Acids; Ammonia; Animals; Disease Models, Animal; Dogs; Hepatic Encephalopathy; Lactulose; Male | 1995 |
Mechanism for lowering blood ammonia levels by lactitol.
Topics: Acetates; Administration, Oral; Ammonia; Animals; Cecum; Charcoal; Colon; Disease Models, Animal; Ga | 1995 |
[Effect of lactitol (NS-4) on the increase in blood and brain ammonia concentration and on coma in newly developed rat models of hepatic coma].
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Lactulose; Male; Rats; Rats | 1995 |
Oceanography and environmental sciences at Miami.
Topics: Ammonia; Animals; Carcinogenicity Tests; Disease Models, Animal; Fishes; Marine Toxins; Neurofibroma | 1995 |
Hyperammonemic encephalopathy due to essential amino acid hyperalimentation.
Topics: Amino Acids, Essential; Ammonia; Animals; Brain Diseases; Disease Models, Animal; Humans; Male; Pare | 1994 |
[Preventive effects of troxipide on a newly developed model of acute gastric mucosal lesion (AGML) induced by ischemia/reperfusion plus ammonia in the rat].
Topics: Acute Disease; Ammonia; Animals; Disease Models, Animal; Gastric Mucosa; Male; Piperidines; Rats; Ra | 1994 |
Effects of zinc on hepatic ornithine transcarbamylase (OTC) activity.
Topics: Ammonia; Animals; Carbon Tetrachloride; Disease Models, Animal; Liver; Liver Cirrhosis, Experimental | 1993 |
Increased densities of binding sites for the peripheral-type benzodiazepine receptor ligand [3H]PK 11195 in congenital ornithine transcarbamylase-deficient sparse fur mouse.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Binding Sites; Brain; Disease Models, Animal | 1993 |
Reversal of behavioral changes in rats subjected to portacaval shunt with oral neomycin therapy.
Topics: Ammonia; Animals; Behavior, Animal; Blood Urea Nitrogen; Disease Models, Animal; Hepatic Encephalopa | 1994 |
Encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit. A clinical and biochemical study.
Topics: Ammonia; Animals; Brain Edema; Disease Models, Animal; Electroencephalography; Hepatic Encephalopath | 1994 |
Generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Animals; Argininosuccinate Synthase; Cel | 1994 |
Gender-dependent reduction of spontaneous motor activity and growth in rats subjected to portacaval shunt.
Topics: Amino Acids; Ammonia; Animals; Body Weight; Disease Models, Animal; Eating; Female; Hepatic Encephal | 1994 |
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Ammonia; Animals; Benzoates; Benzoic Acid; Brain; Coenzym | 1993 |
Free and esterified coenzyme A in the liver and muscles of chronically hyperammonemic mice treated with sodium benzoate.
Topics: Acetyl Coenzyme A; Ammonia; Animals; Benzoates; Benzoic Acid; Chronic Disease; Coenzyme A; Disease M | 1995 |
Rats with gastritis have increased sensitivity to the gastrin stimulatory effects of luminal ammonia.
Topics: Acetates; Ammonia; Animals; Disease Models, Animal; Gastric Mucosa; Gastrins; Gastritis; Iodoacetami | 1996 |
Microencapsulated genetically engineered live E. coli DH5 cells administered orally to maintain normal plasma urea level in uremic rats.
Topics: Administration, Oral; Ammonia; Animals; Capsules; Disease Models, Animal; Escherichia coli; Feasibil | 1996 |
Tyrosine uptake and regional brain monoamine metabolites in a rat model resembling congenital hyperammonemia.
Topics: Amino Acids; Ammonia; Animals; Body Weight; Brain; Disease Models, Animal; Dopamine; Eating; Homovan | 1996 |
The sparse fur mouse as a model for gene therapy in ornithine carbamoyltransferase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Animals; Avoidance Learning; Crosses, Ge | 1995 |
Electrodermal response in nonglabrous skin of freely moving rats: mediation by the sympathetic nervous system and evaluation in an animal model of depression.
Topics: Ammonia; Animals; Depressive Disorder; Disease Models, Animal; Facial Nerve; Galvanic Skin Response; | 1996 |
Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse.
Topics: Ammonia; Animals; Brain Damage, Chronic; Disease Models, Animal; Glutamine; Hair; Metabolism, Inborn | 1995 |
Acute liver failure and hyperammonemia increase peripheral-type benzodiazepine receptor binding and pregnenolone synthesis in mouse brain.
Topics: Acetates; Ammonia; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Liver Failure, Ac | 1995 |
Comparison of the metabolic disturbances caused by end-to-side and side-to-side portacaval shunts.
Topics: Amino Acids; Ammonia; Animals; Blood Glucose; Body Weight; Brain; Disease Models, Animal; Hepatic En | 1996 |
Live E. coli cells to treat uremia.
Topics: Administration, Oral; Ammonia; Animals; Disease Models, Animal; Escherichia coli; Genetic Engineerin | 1997 |
Precipitation of overt encephalopathy in the portacaval shunted rat: towards the development of an adequate model of chronic portal systemic encephalopathy.
Topics: Ammonia; Animals; Blood Urea Nitrogen; Body Weight; Disease Models, Animal; Feasibility Studies; Hep | 1997 |
Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats.
Topics: Ammonia; Animals; Body Water; Brain; Disease Models, Animal; Electroencephalography; Glutamic Acid; | 1997 |
Two models of acute hepatic failure with extensive hepatic necrosis and blood ammonia elevation in small animals.
Topics: Alanine Transaminase; Ammonia; Animals; Bilirubin; Common Bile Duct; Disease Models, Animal; Emulsio | 1997 |
Developmental study of hepatic glutamine synthetase in a mouse model of congenital hyperammonemia.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Body Weight; Disease Models, Animal; Female; | 1997 |
Loss and recovery of liver regeneration in rats with fulminant hepatic failure.
Topics: Albumins; Ammonia; Animals; Bilirubin; Cell Division; Cell Transplantation; Disease Models, Animal; | 1997 |
Positive biochemical effects of a bioartificial liver support system (BALSS) in a porcine fulminant hepatic failure (FHF) model.
Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Bioreactors; Cell Adhesion; Cells, Cultured; | 1998 |
Evaluation of gene therapy for citrullinaemia using murine and bovine models.
Topics: Adenoviruses, Human; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Arginine; Argininosucci | 1998 |
Region-specific changes in CNS muscarinic acetylcholine receptors in a rat model of hyperammonemia.
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Kinetics; Quinuclidinyl Benzilate; Rats; Rats, Wist | 1998 |
Improvement of chronic hepatic encephalopathy in dogs by the benzodiazepine-receptor partial inverse agonist sarmazenil, but not by the antagonist flumazenil.
Topics: Ammonia; Animals; Benzodiazepines; Chronic Disease; Disease Models, Animal; Dogs; Electroencephalogr | 1998 |
Mice deficient in the urea-cycle enzyme, carbamoyl phosphate synthetase I, die during the early neonatal period from hyperammonemia.
Topics: Amino Acid Sequence; Ammonia; Animals; Animals, Newborn; Base Sequence; Brain; Carbamoyl-Phosphate S | 1999 |
Effects of ammonia solution on the gastric mucosa in cirrhotic rats and therapeutic effects of geranylgeranylacetone.
Topics: Ammonia; Animals; Anti-Ulcer Agents; Carbon Tetrachloride; Disease Models, Animal; Diterpenes; Gastr | 1999 |
In vitro and in vivo study of glutamate dehydrogenase encapsulated into mouse erythrocytes by a hypotonic dialysis procedure.
Topics: Ammonia; Animals; Cattle; Dialysis; Disease Models, Animal; Drug Carriers; Erythrocytes; Glutamate D | 1999 |
A reversible model of acute hepatic failure by temporary hepatic ischemia in the pig.
Topics: Acute Disease; Ammonia; Animals; Disease Models, Animal; Ischemia; Liver; Liver Failure; Male; Swine | 2000 |
[Effect of ammonia on the pig respiratory system. Study of the dose-response relation].
Topics: Air Pollutants; Ammonia; Animals; Bronchial Hyperreactivity; Capillary Permeability; Cough; Disease | 1999 |
A novel stable reproducible model of hepatic failure in canines.
Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Amino Acids, Cyclic; Ammonia; Animals; Aspartate | 2000 |
Diabetogenic role of insulin's counterregulatory hormones in the isletectomized, diabetic goby.
Topics: Ammonia; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal | 2000 |
Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease.
Topics: Ammonia; Ammonium Chloride; Animals; Bicarbonates; Disease Models, Animal; Female; Fibrosis; Inflamm | 2001 |
Heliox use in the treatment of acute hyperammonemia.
Topics: Administration, Inhalation; Ammonia; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; | 2001 |
Effects of prostaglandin E(1) on the efficacy of xenogeneic extracorporeal pig liver perfusion in a canine model of acute liver failure.
Topics: Alprostadil; Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Bile; Bile Acids and Salts; | 2001 |
Fermentable carbohydrate and digestive nitrogen excretion.
Topics: Ammonia; Animals; Cecum; Dietary Carbohydrates; Dietary Proteins; Disease Models, Animal; Disease Pr | 2001 |
In vivo estimation of bioartificial liver with recombinant HepG2 cells using pigs with ischemic liver failure.
Topics: Ammonia; Animals; Blood Coagulation; Disease Models, Animal; Glucose; Glutamate-Ammonia Ligase; Glut | 2001 |
[Nitrogen detoxification in artificially-fed zinc-deficient rats].
Topics: Alkaline Phosphatase; Ammonia; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthas | 2001 |
The treatment of ammonia poisoning by taurine in combination with a broncholytic drug.
Topics: Administration, Inhalation; Ammonia; Animals; Antidotes; Antioxidants; Bronchodilator Agents; Diseas | 2000 |
Establishment of an animal model of chronic atrophic gastritis and a study on the factors inducing atrophy.
Topics: Ammonia; Animals; Atrophy; Deoxycholic Acid; Disease Models, Animal; Ethanol; Gastric Mucosa; Gastri | 2001 |
[Metabolic disorders in experimental hepatic insufficiency and parenteral feeding].
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Blood Coagulation; Blood Transfusion; Choline; D | 1977 |
Primary dilation of the cerebral resistance vessels as a cause of increased intracranial pressure.
Topics: Acute Disease; Ammonia; Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Electro | 1978 |
Comparison of mild vs severe pressure overload on the enzymatic activity of myosin in the canine ventricles.
Topics: Adenosine Triphosphatases; Ammonia; Animals; Blood Pressure; Calcium; Disease Models, Animal; Dogs; | 1975 |
Hyperammonemic coma after hepatectomy in germ-free rats.
Topics: Ammonia; Animals; Bacteria; Bacterial Toxins; Disease Models, Animal; Germ-Free Life; Hepatectomy; H | 1979 |
A model of fulminant hepatic failure in the rabbit.
Topics: Alkaline Phosphatase; Amino Acids; Ammonia; Animals; Aspartate Aminotransferases; Blood Coagulation | 1978 |
Hepatic metabolic changes following energy deprivation by ammonia in patients and rabbits with jaundice.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Ammonium Chloride; | 1977 |
Experience of treatment in the Amanita phalloides poisoning (clinical and experimental observations).
Topics: Adolescent; Adult; Alanine Transaminase; Amanita; Ammonia; Animals; Aspartate Aminotransferases; Bio | 1977 |
Histochemical studies in experimental portal-systemic encephalopathy.
Topics: Alzheimer Disease; Ammonia; Animals; Cerebral Cortex; Disease Models, Animal; Glutamate Dehydrogenas | 1976 |
Effect of ammonia on cerebral metabolism of rats with portocaval shunts.
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Male; Portacaval Shunt, Sur | 1976 |
Total devascularization of the Liver: an experimental model of acute liver failure.
Topics: Acute Disease; Ammonia; Animals; Disease Models, Animal; Glucose; Lactates; Liver; Liver Diseases; P | 1976 |
Projections and measurements of in vivo performance of liquid membrane capsules.
Topics: Ammonia; Animals; Capsules; Disease Models, Animal; Dogs; In Vitro Techniques; Intestine, Small; Mem | 1976 |
Methionine-induced hepatic coma in dogs.
Topics: Administration, Oral; Ammonia; Animals; Brain; Disease Models, Animal; Dogs; Hepatic Encephalopathy; | 1975 |
Quinolinate in brain and cerebrospinal fluid in rat models of congenital hyperammonemia.
Topics: Acetates; Ammonia; Animals; Brain; Disease Models, Animal; Hydroxyindoleacetic Acid; Male; Metabolis | 1992 |
The isolated perfused rat liver as an experimental model.
Topics: Albumins; Amino Acids; Ammonia; Animals; Biological Availability; Disease Models, Animal; Evaluation | 1992 |
Interactions of ibuprofen with influenza infection and hyperammonemia in an animal model of Reye's syndrome.
Topics: Alanine Transaminase; Ammonia; Animals; Arginine; Aspartate Aminotransferases; Diet; Disease Models, | 1992 |
A reliable method for the production of antral gastric ulcer by a combination of 2-deoxy-D-glucose, aspirin and ammonia in rats.
Topics: Administration, Oral; Ammonia; Animals; Aspirin; Deoxyglucose; Disease Models, Animal; Drug Interact | 1991 |
A new surgical model of acute liver failure in the pig: experimental procedure and analysis of liver injury.
Topics: Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Female; Hepatectom | 1991 |
Congenital portosystemic shunts (PSS) in dogs are a genetic disorder.
Topics: Ammonia; Animals; Disease Models, Animal; Dog Diseases; Dogs; Female; Hepatic Encephalopathy; Male; | 1991 |
In vivo and in vitro rat model for cyclosporine-induced proximal tubular toxicity.
Topics: Acetylglucosaminidase; Ammonia; Animals; Citrates; Citric Acid; Cyclosporins; Disease Models, Animal | 1991 |
[Possibilities of hemosorption using a fibrous sorbent in acute hepatic failure (experimental study)].
Topics: Acrylic Resins; Acute Disease; Ammonia; Animals; Bilirubin; Blood Proteins; Disease Models, Animal; | 1990 |
The effect of L-carnitine supplementation in 4 pentenoic acid treated rats.
Topics: Ammonia; Animals; Blood Glucose; Carnitine; Disease Models, Animal; Fatty Acids, Monounsaturated; Fa | 1990 |
Gas-exchange impairment: its correlation to lung mechanics in acute airway obstruction (studies on a rabbit asthma model).
Topics: Airway Obstruction; Ammonia; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Disease Models, | 1990 |
The effect of blood ingestion on brain serotonin synthesis in portacaval-shunted rats.
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Blood; Brain; Disease Models, Animal; Explorator | 1987 |
Ammonia-complement interaction in the pathogenesis of progressive renal injury.
Topics: Ammonia; Animals; Complement System Proteins; Disease Models, Animal; Drug Interactions; Humans; Kid | 1989 |
Alterations in plasma amino acids and hepatic enzymes in the 4-pentenoic acid model of Reye's syndrome.
Topics: Amino Acids; Ammonia; Animals; Disease Models, Animal; Fatty Acids, Monounsaturated; Glutamate Dehyd | 1989 |
A simple animal model of hyperammonemia.
Topics: Acetates; Ammonia; Animals; Citrulline; Disease Models, Animal; Glutamate Dehydrogenase; Liver; Male | 1989 |
Reduced somatostatin-like immunoreactivity in the brain of dogs with an Eck fistula.
Topics: Amino Acids; Ammonia; Animals; Chromatography, Gel; Disease Models, Animal; Dogs; Hepatic Encephalop | 1987 |
Brain cholecystokinin depletion in rats with acute liver failure.
Topics: Ammonia; Animals; Blood Glucose; Brain; Cerebral Cortex; Cholecystokinin; Disease Models, Animal; Hy | 1989 |
Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits.
Topics: Acetates; Acetic Acid; Ammonia; Animals; Blood Glucose; Disease Models, Animal; Electroencephalograp | 1989 |
Arginine deficiency, hyperammonemia and Reye's syndrome in ferrets.
Topics: Ammonia; Animals; Animals, Laboratory; Arginine; Carnivora; Disease Models, Animal; Ferrets; Influen | 1985 |
Correlation between electroencephalographic and biochemical indices in acute hepatic encephalopathy in rats.
Topics: Acute Disease; Alanine Transaminase; Amino Acids; Ammonia; Animals; Disease Models, Animal; Electroe | 1987 |
A surgical model of fulminant hepatic failure in the rabbit: different effects of end-to-side versus small-diameter side-to-side portacaval shunt.
Topics: Ammonia; Animals; Blood Coagulation Factors; Disease Models, Animal; Electroencephalography; Female; | 1987 |
Differences in virulence within the species Bacteroides gingivalis.
Topics: Ammonia; Animals; Bacteroides; Bacteroides Infections; Blood Bactericidal Activity; Disease Models, | 1987 |
Behavioral and neurotransmitter changes in the urease-infused rat: a model of congenital hyperammonemia.
Topics: Ammonia; Animals; Behavior, Animal; Biogenic Amines; Brain; Disease Models, Animal; Drug Implants; F | 1986 |
A reproducible model of acute hepatic failure by transient ischemia in the pig.
Topics: Amino Acids; Ammonia; Animals; Disease Models, Animal; Electroencephalography; Electrophysiology; Fi | 1987 |
Biochemical and morphological characteristics of a mouse model of Reye's syndrome induced by the interaction of influenza B virus and a chemical emulsifier.
Topics: Ammonia; Animals; Animals, Suckling; Disease Models, Animal; Emulsions; Female; Influenza B virus; L | 1986 |
Metabolic and mitochondrial morphological changes that mimic Reye syndrome after endotoxin administration to rats.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Blood Glucose; Disease Models, | 1985 |
Neuron-specific mitochondrial degeneration induced by hyperammonemia and octanoic acidemia.
Topics: Ammonia; Animals; Brain; Caprylates; Disease Models, Animal; Dogs; In Vitro Techniques; Mitochondria | 1985 |
The pathophysiology of hyperchloremic metabolic acidosis after urinary diversion through intestinal segments.
Topics: Acidosis; Ammonia; Animals; Chlorides; Disease Models, Animal; Dogs; Electrolytes; Female; Ileum; Ki | 1985 |
Investigation of an animal model of a Reye-like syndrome caused by Margosa oil.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Blood Glucose; Brain Edema; Dis | 1985 |
Transient hyperammonemia during aging in ornithine transcarbamylase-deficient, sparse-fur mice.
Topics: Aging; Ammonia; Animals; Body Weight; Disease Models, Animal; Hair; Liver; Mice; Mice, Mutant Strain | 1985 |
Renal ammoniagenesis and tissue glutamine, glutamine synthetase, and glutaminase I levels in potassium-deficient rats.
Topics: Ammonia; Animals; Carbon Dioxide; Chlorides; Disease Models, Animal; Glutamate-Ammonia Ligase; Gluta | 1973 |
Urease-inhibiting action of some drugs in vitro and in vivo.
Topics: Ammonia; Animals; Anti-Bacterial Agents; Ascorbic Acid; Bacitracin; Chloramphenicol; Chlortetracycli | 1970 |
The astrocyte response in experimental portal-systemic encephalopathy: an electron microscopic study.
Topics: Ammonia; Animals; Cell Membrane; Cell Nucleus; Cerebral Cortex; Cytoplasm; Cytoplasmic Granules; Dis | 1974 |
Experimental ammonia encephalopathy in the primate.
Topics: Ammonia; Animals; Brain; Brain Diseases; Disease Models, Animal; Electroencephalography; Haplorhini; | 1972 |
The Eck fistula rat: definition of an experimental model.
Topics: Adrenal Glands; Ammonia; Animals; Atrophy; Body Weight; Cerebral Cortex; Coprophagia; Disease Models | 1972 |
Ultrastructural responses of the astrocytes to portocaval anastomosis in the rat.
Topics: Ammonia; Animals; Brain; Brain Diseases; Carbon Tetrachloride Poisoning; Caudate Nucleus; Cerebellar | 1973 |
Effects of colectomy on encephalopathy in rats with protacaval shunts.
Topics: Ammonia; Animals; Brain Diseases; Colectomy; Colon; Disease Models, Animal; Electroencephalography; | 1974 |
Abnormal orotic acid metabolism associated with acute hyperammonaemia in the rat.
Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Carbon Radioisotopes; Carboxy-Lyas | 1974 |
Brain histology and behavior of mice injected with urease.
Topics: Ammonia; Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Cell Nucleus; Disease | 1974 |
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosp | 1974 |
Cerebral metabolic state following complete compression ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammo | 1974 |
An experimental model for the study of hepatic encephalopathy.
Topics: Ammonia; Animals; Bilirubin; Blood Glucose; Cell Nucleolus; Cell Nucleus; Cerebral Cortex; Disease M | 1974 |
Effect of low protein diet and hyperammonemia on liver glutaminase activity in the rat.
Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Body Weight; Dietary Proteins; Dis | 1974 |
Effects of haemoperfusion through charcoal or XAD-2 resin on an animal model of fulminant liver failure.
Topics: Ammonia; Animals; Bilirubin; Carbon Radioisotopes; Charcoal; Disease Models, Animal; Dogs; Filtratio | 1974 |
Renal metabolism of glutamine in dogs during infusion of -ketoglutaric acid.
Topics: Acidosis; Ammonia; Ammonium Chloride; Animals; Cell Membrane Permeability; Disease Models, Animal; D | 1972 |
Experimental prepatent schistosomiasis mansoni: quantitative analyses of proteins, enzyme activity and free amino acids in mouse serum.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Animals; Aspartate Aminotransferas | 1972 |
Acute hepatic coma: a canine model.
Topics: Ammonia; Animals; Aspartate Aminotransferases; Blood Coagulation Tests; Blood Pressure; Blood Urea N | 1972 |
Changes in the cerebellar cortex in rats after portocaval anastomosis.
Topics: Ammonia; Animals; Cerebellar Cortex; Cerebellar Diseases; Dementia; Dendrites; Disease Models, Anima | 1972 |
Eck's fistula encephalopathy in germfree dogs.
Topics: Ammonia; Animals; Body Weight; Brain; Brain Diseases; Disease Models, Animal; Dogs; Germ-Free Life; | 1971 |
[Modification of experimentally induced endogenous hyperammoniemia by amino acids in the rat].
Topics: Amino Acids; Ammonia; Anesthesia, General; Animals; Arginine; Aspartic Acid; Citric Acid Cycle; Depr | 1970 |
Eck fistula encephalopathy: long-term studies in primates.
Topics: Ammonia; Animals; Body Weight; Brain; Brain Diseases; Dietary Proteins; Disease Models, Animal | 1971 |
Hemodialysis of ammonium nitrogen.
Topics: Ammonia; Animals; Disease Models, Animal; Dogs; Extracorporeal Circulation; Hepatic Encephalopathy; | 1971 |
[Encephalopathy of the rat with portacaval shunt: an animal model for therapeutic experiments].
Topics: Ammonia; Animals; Body Weight; Brain Diseases; Carbohydrates; Disease Models, Animal; Motor Activity | 1971 |