ammonium hydroxide has been researched along with Cirrhosis in 23 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings demonstrated that ADSC-derived exosomes could efficiently alleviate hepatic fibrosis by suppressing HSCs activation and remodeling glutamine and ammonia metabolism mediated by hepatocellular glutamine synthetase, which might be a novel and promising anti-fibrotic therapeutics for hepatic fibrosis disease." | 8.12 | ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis. ( Feng, J; Fu, Q; Guo, J; Ling, B; Ning, K; Wang, J; Wu, B; Xiu, G; Xu, J, 2022) |
| "We treated a 49-yr-old man with neostigmine, who had liver cirrhosis, acute hepatic encephalopathy, and acute intestinal pseudoobstruction." | 7.73 | Neostigmine for the treatment of acute hepatic encephalopathy with acute intestinal pseudo-obstruction in a cirrhotic patient. ( Choi, SK; Joo, YE; Kim, HS; Kim, SJ; Park, CH; Rew, JS, 2005) |
| "These findings demonstrated that ADSC-derived exosomes could efficiently alleviate hepatic fibrosis by suppressing HSCs activation and remodeling glutamine and ammonia metabolism mediated by hepatocellular glutamine synthetase, which might be a novel and promising anti-fibrotic therapeutics for hepatic fibrosis disease." | 4.12 | ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis. ( Feng, J; Fu, Q; Guo, J; Ling, B; Ning, K; Wang, J; Wu, B; Xiu, G; Xu, J, 2022) |
| "In 34 patients with HCM, PET was performed using (13)N-labeled ammonia during hyperemia induced by intravenous dipyridamole." | 3.74 | Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy. ( Betti, I; Camici, PG; Casolo, G; Cecchi, F; Olivotto, I; Pupi, A; Rega, L; Sciagrà, R; Sotgia, B, 2008) |
| "We treated a 49-yr-old man with neostigmine, who had liver cirrhosis, acute hepatic encephalopathy, and acute intestinal pseudoobstruction." | 3.73 | Neostigmine for the treatment of acute hepatic encephalopathy with acute intestinal pseudo-obstruction in a cirrhotic patient. ( Choi, SK; Joo, YE; Kim, HS; Kim, SJ; Park, CH; Rew, JS, 2005) |
| " We have conducted studies to determine whether the protection afforded by the administration of sodium bicarbonate is sustained and prevents development of uremia during chronic administration and whether the effects of the administration of ammonium chloride and sodium bicarbonate are also observed in a different model of polycystic kidney disease, the CD1-pcy/pcy mouse." | 3.71 | Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease. ( Branden, MG; Cowley, BD; Gattone, VH; Torres, VE; Yoshida, I, 2001) |
| "Hyperlipidemia and oxidative stress with elevated oxidized low-density lipoprotein (ox-LDL) exacerbate hepatic inflammation and fibrosis." | 1.72 | Effects of PCSK-9 Inhibition by Alirocumab Treatments on Biliary Cirrhotic Rats. ( Chang, CC; Chuang, CL; Hou, MC; Hsu, SJ; Huang, HC; Lee, FY, 2022) |
| "Although lupus nephritis (LN) is mostly characterized by glomerular involvement, tubular injury is indispensable in its pathogenesis and progression." | 1.56 | Value of monitoring urine ammonia at time of biopsy in patients with lupus nephritis. ( Duan, S; Li, Q; Liu, S; Wan, H; Wu, L; Xing, C; Yuan, Y; Zhang, B; Zhang, C; Zhu, H, 2020) |
| "The development of fibrosis is the most important factor contributing to NASH-associated morbidity and mortality." | 1.48 | Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis. ( Andreola, F; De Chiara, F; Jalan, R; Mookerjee, RP; Rombouts, K; Thomsen, KL; Vilstrup, H, 2018) |
| "Portal hypertension affects portal-systemic shunt which leads to hepatic encephalopathy that the vascular modulation might influence severity of hepatic encephalopathy." | 1.46 | Effects of raloxifene on portal hypertension and hepatic encephalopathy in cirrhotic rats. ( Chang, CC; Chang, T; Chuang, CL; Hsin, IF; Hsu, SJ; Huang, HC; Lee, FY; Lee, SD; Lee, WS, 2017) |
| "Hindlimb ischemia was induced in nude mice by ligation and excision of the left femoral artery (n = 5) or the left iliac artery (n = 10)." | 1.34 | (13)N-ammonia PET as a measurement of hindlimb perfusion in a mouse model of peripheral artery occlusive disease. ( Abizanda, G; Aranguren, XL; Collantes, M; Ecay, M; Martí-Climent, JM; Peñuelas, I; Prósper, F; Quincoces, G; Richter, JA; Uriz, M, 2007) |
| "In patients with acute liver failure, hyperammonemia is associated with cerebral herniation." | 1.31 | Splanchnic and leg exchange of amino acids and ammonia in acute liver failure. ( Clemmesen, JO; Kondrup, J; Ott, P, 2000) |
| "Hepatic encephalopathy is a syndrome characterized by increased blood ammonia level and is one of the major complications of cirrhosis." | 1.31 | The protective effect of HD-03 in CCl4-induced hepatic encephalopathy in rats. ( Anturlikar, SD; Gopumadhavan, S; Mitra, SK; Seshadri, SJ; Venkataranganna, MV; Venkatesha Udupa, U, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 10 (43.48) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, HC | 2 |
| Hsu, SJ | 2 |
| Chang, CC | 2 |
| Chuang, CL | 2 |
| Hou, MC | 1 |
| Lee, FY | 2 |
| Wu, B | 1 |
| Feng, J | 1 |
| Guo, J | 1 |
| Wang, J | 1 |
| Xiu, G | 1 |
| Xu, J | 2 |
| Ning, K | 1 |
| Ling, B | 1 |
| Fu, Q | 1 |
| Tranah, TH | 1 |
| Ballester, MP | 3 |
| Carbonell-Asins, JA | 3 |
| Jalan, R | 5 |
| Shawcross, DL | 1 |
| Zhu, R | 1 |
| Liu, L | 1 |
| Zhang, G | 1 |
| Dong, J | 1 |
| Ren, Z | 1 |
| Li, Z | 1 |
| Rose, CF | 1 |
| Tapper, EB | 1 |
| Bajaj, JS | 1 |
| Balcar, L | 1 |
| Reiberger, T | 1 |
| Dong, JJ | 1 |
| Zhang, QY | 1 |
| Cai, YJ | 1 |
| Jing, H | 1 |
| Wang, S | 1 |
| Wang, Y | 1 |
| Shen, N | 1 |
| Gao, XJ | 1 |
| Zhu, H | 1 |
| Wan, H | 1 |
| Duan, S | 1 |
| Zhang, C | 1 |
| Li, Q | 1 |
| Liu, S | 1 |
| Wu, L | 1 |
| Zhang, B | 1 |
| Xing, C | 1 |
| Yuan, Y | 1 |
| Thomsen, KL | 1 |
| De Chiara, F | 1 |
| Rombouts, K | 1 |
| Vilstrup, H | 1 |
| Andreola, F | 1 |
| Mookerjee, RP | 1 |
| Choudhary, NS | 1 |
| Saigal, S | 1 |
| Saraf, N | 1 |
| Soin, AS | 1 |
| Singh, S | 1 |
| Suresh, S | 1 |
| McClave, SA | 1 |
| Cave, M | 1 |
| Lee, WS | 1 |
| Hsin, IF | 1 |
| Chang, T | 1 |
| Lee, SD | 1 |
| Sotgia, B | 1 |
| Sciagrà, R | 1 |
| Olivotto, I | 1 |
| Casolo, G | 1 |
| Rega, L | 1 |
| Betti, I | 1 |
| Pupi, A | 1 |
| Camici, PG | 1 |
| Cecchi, F | 1 |
| Nishiguchi, S | 1 |
| Shiomi, S | 1 |
| Kawamura, E | 1 |
| Ishizu, H | 1 |
| Habu, D | 1 |
| Torii, K | 1 |
| Kawabe, J | 1 |
| Park, CH | 1 |
| Joo, YE | 1 |
| Kim, HS | 1 |
| Choi, SK | 1 |
| Rew, JS | 1 |
| Kim, SJ | 1 |
| Olde Damink, SW | 1 |
| Dejong, CH | 1 |
| Deutz, NE | 1 |
| Redhead, DN | 1 |
| Hayes, PC | 1 |
| Soeters, PB | 1 |
| Peñuelas, I | 1 |
| Aranguren, XL | 1 |
| Abizanda, G | 1 |
| Martí-Climent, JM | 1 |
| Uriz, M | 1 |
| Ecay, M | 1 |
| Collantes, M | 1 |
| Quincoces, G | 1 |
| Richter, JA | 1 |
| Prósper, F | 1 |
| Clemmesen, JO | 1 |
| Kondrup, J | 1 |
| Ott, P | 1 |
| Torres, VE | 1 |
| Cowley, BD | 1 |
| Branden, MG | 1 |
| Yoshida, I | 1 |
| Gattone, VH | 1 |
| Mitra, SK | 1 |
| Venkataranganna, MV | 1 |
| Gopumadhavan, S | 1 |
| Anturlikar, SD | 1 |
| Seshadri, SJ | 1 |
| Venkatesha Udupa, U | 1 |
| Sakai, T | 1 |
| Katoh, T | 1 |
| Asada, K | 1 |
| Yagi, K | 1 |
| Yoshida, R | 1 |
2 reviews available for ammonium hydroxide and Cirrhosis
| Article | Year |
|---|---|
Treating Every Needle in the Haystack: Hyperammonemic Encephalopathy and Severe Malnutrition After Bariatric Surgery-A Case Report and Review of the Literature.
Topics: Adult; Ammonia; Brain Diseases, Metabolic; Diagnostic Errors; Female; Fibrosis; Gastric Bypass; Huma | 2015 |
Portal hepatic venous shunt via an intrahepatic portal vein aneurysm.
Topics: Aged; Ammonia; Aneurysm; Fibrosis; Fistula; Hepatic Veins; Humans; Liver; Magnetic Resonance Imaging | 1992 |
1 trial available for ammonium hydroxide and Cirrhosis
| Article | Year |
|---|---|
Kidney plays a major role in ammonia homeostasis after portasystemic shunting in patients with cirrhosis.
Topics: Adaptation, Physiological; Ammonia; Female; Fibrosis; Homeostasis; Humans; Kidney; Male; Middle Aged | 2006 |
20 other studies available for ammonium hydroxide and Cirrhosis
| Article | Year |
|---|---|
Effects of PCSK-9 Inhibition by Alirocumab Treatments on Biliary Cirrhotic Rats.
Topics: Ammonia; Animals; Antibodies, Monoclonal, Humanized; Cholesterol, LDL; Fibrosis; Hepatic Encephalopa | 2022 |
ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis.
Topics: Ammonia; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diethylnitrosamine; Exosomes; Fib | 2022 |
Reply to: "Ammonia and prognosis of cirrhosis: A new perspective for identifying high risk patients".
Topics: Ammonia; Fibrosis; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Prognosis | 2023 |
The pathogenesis of gut microbiota in hepatic encephalopathy by the gut-liver-brain axis.
Topics: Ammonia; Brain; Fibrosis; Gastrointestinal Microbiome; Hepatic Encephalopathy; Humans; Hyperammonemi | 2023 |
Measuring and Interpreting Ammonia Levels in Cirrhosis.
Topics: Ammonia; Fibrosis; Hepatic Encephalopathy; Humans; Liver Cirrhosis | 2023 |
Ammonia predicts clinical outcomes in cirrhosis - but there are caveats to consider.
Topics: Ammonia; Fibrosis; Hepatic Encephalopathy; Humans; Liver Cirrhosis | 2023 |
Reply to: "Ammonia predicts clinical outcomes in cirrhosis - but there are caveats to consider".
Topics: Ammonia; Fibrosis; Hepatic Encephalopathy; Humans; Liver Cirrhosis | 2023 |
Letter: Exploring the clinical utility of ammonia in critically ill patients with cirrhosis: More to do?
Topics: Ammonia; Critical Illness; Fibrosis; Humans; Liver Cirrhosis | 2023 |
Environmental contaminant ammonia triggers epithelial-to-mesenchymal transition-mediated jejunal fibrosis with the disassembly of epithelial cell-cell contacts in chicken.
Topics: Ammonia; Animals; Chickens; Epithelial Cells; Fibrosis; Humans; Jejunum; Proteomics | 2020 |
Value of monitoring urine ammonia at time of biopsy in patients with lupus nephritis.
Topics: Acidosis, Renal Tubular; Ammonia; Atrophy; Biopsy; Creatinine; Female; Fibrosis; Glomerular Filtrati | 2020 |
Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis.
Topics: Ammonia; Animals; Biopsy; Disease Models, Animal; Disease Progression; Fibrosis; Hepatic Stellate Ce | 2018 |
Letter to Editor: Prognostic Role of Ammonia in Patients With Cirrhosis.
Topics: Ammonia; Fibrosis; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Prognosis | 2019 |
Effects of raloxifene on portal hypertension and hepatic encephalopathy in cirrhotic rats.
Topics: Ammonia; Animals; Body Weight; Female; Fibrosis; Gene Expression Regulation; Hemodynamics; Hepatic E | 2017 |
Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy.
Topics: Adolescent; Adult; Aged; Ammonia; Cardiomyopathy, Hypertrophic; Contrast Media; Coronary Circulation | 2008 |
Evaluation of ammonia metabolism in the skeletal muscles of patients with cirrhosis using N-13 ammonia PET.
Topics: Aged; Amino Acids, Branched-Chain; Ammonia; Female; Fibrosis; Humans; Male; Metabolic Clearance Rate | 2003 |
Neostigmine for the treatment of acute hepatic encephalopathy with acute intestinal pseudo-obstruction in a cirrhotic patient.
Topics: Air; Ammonia; Blood Pressure; Cholinesterase Inhibitors; Electrolytes; Enema; Fibrosis; Hepatic Ence | 2005 |
(13)N-ammonia PET as a measurement of hindlimb perfusion in a mouse model of peripheral artery occlusive disease.
Topics: Ammonia; Animals; Arterial Occlusive Diseases; Fibrosis; Hindlimb; Ischemia; Male; Mice; Mice, Nude; | 2007 |
Splanchnic and leg exchange of amino acids and ammonia in acute liver failure.
Topics: Adult; Alanine; Amino Acids; Ammonia; Blood Urea Nitrogen; Citrulline; Female; Femoral Artery; Femor | 2000 |
Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease.
Topics: Ammonia; Ammonium Chloride; Animals; Bicarbonates; Disease Models, Animal; Female; Fibrosis; Inflamm | 2001 |
The protective effect of HD-03 in CCl4-induced hepatic encephalopathy in rats.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Astrocytes; Carbon Tetrachlorid | 2001 |