Page last updated: 2024-10-16

ammonium hydroxide and Bipolar Disorder

ammonium hydroxide has been researched along with Bipolar Disorder in 11 studies

azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that carnitine deficiency is associated with the VPA dose and the serum VPA level in patients with bipolar disorder."7.96Association Between the Serum Carnitine Level and Ammonia and Valproic Acid Levels in Patients with Bipolar Disorder. ( Ishioka, M; Kubo, K; Miyazaki, K; Nakagami, T; Shimoda, K; Sugawara, N; Tarakita, N; Yasui-Furukori, N; Yokoyama, S, 2020)
"Valproic acid, a branched short-chain fatty acid, has numerous action mechanisms which turn it into a broad spectrum anticonvulsant drug and make its use possible in some other pathologies such as bipolar disorder."7.80Hyperammonemia associated with valproic acid concentrations. ( Alvariza, S; Fagiolino, P; Guevara, N; Ibarra, M; Magallanes, L; Maldonado, C; Olano, I; Olmos, I; Vázquez, M, 2014)
"We describe a patient with lithium-induced nephrogenic diabetes insipidus in whom detailed investigations of distal tubular function were performed."7.66Lithium-induced nephrogenic diabetes insipidus: studies of tubular function and pathogenesis. ( Alroy, GG; Better, OS; Chaimovitz, C; Rapoport, J, 1979)
" Three groups of patients were studied: (A) epileptic under phenytoin monotherapy (n = 31); (B) with bipolar disorder under valproic acid treatment (n = 28); (C) elderly (n = 41)."5.22Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia. ( Fagiolino, P; González, R; Guevara, N; Maldonado, C; Queijo, C; Vázquez, M, 2016)
"These findings suggest that carnitine deficiency is associated with the VPA dose and the serum VPA level in patients with bipolar disorder."3.96Association Between the Serum Carnitine Level and Ammonia and Valproic Acid Levels in Patients with Bipolar Disorder. ( Ishioka, M; Kubo, K; Miyazaki, K; Nakagami, T; Shimoda, K; Sugawara, N; Tarakita, N; Yasui-Furukori, N; Yokoyama, S, 2020)
"Valproic acid, a branched short-chain fatty acid, has numerous action mechanisms which turn it into a broad spectrum anticonvulsant drug and make its use possible in some other pathologies such as bipolar disorder."3.80Hyperammonemia associated with valproic acid concentrations. ( Alvariza, S; Fagiolino, P; Guevara, N; Ibarra, M; Magallanes, L; Maldonado, C; Olano, I; Olmos, I; Vázquez, M, 2014)
"We describe a patient with lithium-induced nephrogenic diabetes insipidus in whom detailed investigations of distal tubular function were performed."3.66Lithium-induced nephrogenic diabetes insipidus: studies of tubular function and pathogenesis. ( Alroy, GG; Better, OS; Chaimovitz, C; Rapoport, J, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Yokoyama, S1
Yasui-Furukori, N1
Nakagami, T1
Miyazaki, K1
Ishioka, M1
Tarakita, N1
Kubo, K1
Sugawara, N1
Shimoda, K1
Kopel, J1
Grooms, A1
Ganapathy, V1
Clothier, J1
Vázquez, M2
Fagiolino, P2
Maldonado, C2
Olmos, I1
Ibarra, M1
Alvariza, S1
Guevara, N2
Magallanes, L1
Olano, I1
Queijo, C1
González, R1
Wagner, KD1
Redden, L1
Kowatch, RA1
Wilens, TE1
Segal, S1
Chang, K1
Wozniak, P1
Vigna, NV1
Abi-Saab, W1
Saltarelli, M1
BARUK, H1
Raby, WN1
Panikkar, GP1
Gilman, SM1
Rapoport, J1
Chaimovitz, C1
Alroy, GG1
Better, OS1
Rivelli, M1
el-Mallakh, RS1
Nelson, WH1
Capalna, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Depakote ER for the Treatment of Bipolar Disorder in Children and Adolescents[NCT00067262]Phase 3150 participants Interventional2003-03-31Completed
An Open-Label Long-Term Study to Evaluate the Safety of Depakote Extended Release Tablets in the Treatment of Mania Associated With Bipolar Disorder in Children and Adolescents[NCT00195767]Phase 3150 participants Interventional2004-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for ammonium hydroxide and Bipolar Disorder

ArticleYear
Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia.
    BioMed research international, 2016, Volume: 2016

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Aged, 80 and over; Ammonia; Bipolar Disorder; Carnitine; E

2016
A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2009, Volume: 48, Issue:5

    Topics: Adolescent; Ammonia; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Child; Delayed-Action

2009
A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2009, Volume: 48, Issue:5

    Topics: Adolescent; Ammonia; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Child; Delayed-Action

2009
A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2009, Volume: 48, Issue:5

    Topics: Adolescent; Ammonia; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Child; Delayed-Action

2009
A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2009, Volume: 48, Issue:5

    Topics: Adolescent; Ammonia; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Child; Delayed-Action

2009

Other Studies

9 other studies available for ammonium hydroxide and Bipolar Disorder

ArticleYear
Association Between the Serum Carnitine Level and Ammonia and Valproic Acid Levels in Patients with Bipolar Disorder.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:5

    Topics: Ammonia; Anticonvulsants; Bipolar Disorder; Carnitine; Epilepsy; Female; Humans; Male; Middle Aged;

2020
Metformin, valproic acid, and starvation induce seizures in a patient with partial SLC13A5 deficiency: a case of pharmaco-synergistic heterozygosity.
    Psychiatric genetics, 2021, 02-01, Volume: 31, Issue:1

    Topics: Adult; Amino Acid Substitution; Ammonia; Animals; Anticonvulsants; Autistic Disorder; Bipolar Disord

2021
Hyperammonemia associated with valproic acid concentrations.
    BioMed research international, 2014, Volume: 2014

    Topics: Adolescent; Adult; Ammonia; Bipolar Disorder; Carnitine; Child; Dietary Supplements; Dose-Response R

2014
[RECENT RESEARCH ON BILIARY CATATONINE, ELECTROPHORETIC DISORDERS OF THE SERUM AND AMMONIA EXCESS IN BLOOD IN CATATONIA AND SEVERAL PERIODIC PSYCHOSES].
    Confinia psychiatrica. Borderland of psychiatry. Grenzgebiete der Psychiatrie. Les Confins de la psychiatrie, 1963, Volume: 6

    Topics: Ammonia; Bile; Bipolar Disorder; Blood; Blood Protein Electrophoresis; Blood Sedimentation; Catatoni

1963
Carnitine for valproic acid-induced hyperammonemia.
    The American journal of psychiatry, 1997, Volume: 154, Issue:8

    Topics: Adult; Ammonia; Bipolar Disorder; Carbamoyl-Phosphate Synthase (Ammonia); Carnitine; Depressive Diso

1997
Valproate-induced hyperammonemia in the psychiatric setting: 2 cases.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:8

    Topics: Adult; Ammonia; Anticonvulsants; Bipolar Disorder; Humans; Male; Mental Disorders; Middle Aged; Psyc

1999
Lithium-induced nephrogenic diabetes insipidus: studies of tubular function and pathogenesis.
    Israel journal of medical sciences, 1979, Volume: 15, Issue:9

    Topics: Ammonia; Bipolar Disorder; Diabetes Insipidus; Electrolytes; Female; Glomerular Filtration Rate; Hum

1979
Carbamazepine-associated asterixis and hyperammonemia.
    The American journal of psychiatry, 1988, Volume: 145, Issue:2

    Topics: Adult; Ammonia; Bipolar Disorder; Carbamazepine; Humans; Male; Movement Disorders; Posture

1988
Exploration of the bodily functions and functional disorders of the endogenous depressions.
    Revue roumaine de physiologie, 1968, Volume: 5, Issue:1

    Topics: Acetylcholine; Adenine Nucleotides; Amino Acids; Ammonia; Bipolar Disorder; Brain; Carbon Dioxide; D

1968