ammonium hydroxide has been researched along with Alkalosis, Respiratory in 17 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
Alkalosis, Respiratory: A state due to excess loss of carbon dioxide from the body. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The existence of respiratory alkalosis and multiple myeloma should prompt a search for hyperammonemia." | 1.40 | [Hyperammonemic encephalopathy in multiple myeloma]. ( Aujesky, D; Oestmann, A, 2014) |
| "During the initial high pH period, respiratory alkalosis had no effect on NH3 production in comparison with perfusions at a normal pH." | 1.27 | Response of ammoniagenesis to acute alkalosis. ( Goyal, M; Tannen, RL, 1984) |
| "Acute respiratory alkalosis (blood pH, 7." | 1.27 | Renal metabolism and ammoniagenesis during acute respiratory alkalosis in the dog. ( Cardoso, M; Duplain, M; Gougoux, A; Vinay, P, 1984) |
| "Respiratory acidosis is due to alveolar hypoventilation." | 1.26 | Acute acid-base disorders. 2. Specific disturbances. ( Quintanilla, AP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oestmann, A | 1 |
| Aujesky, D | 1 |
| VANAMEE, P | 1 |
| POPPELL, JW | 1 |
| GLICKSMAN, AS | 1 |
| RANDALL, HT | 1 |
| ROBERTS, KE | 1 |
| Tannen, RL | 2 |
| Goyal, M | 1 |
| Gougoux, A | 1 |
| Vinay, P | 1 |
| Cardoso, M | 1 |
| Duplain, M | 1 |
| Narins, RG | 1 |
| Emmett, M | 1 |
| Rascoff, J | 1 |
| Jones, ER | 1 |
| Relman, AS | 1 |
| Brusilow, SW | 2 |
| Maestri, NE | 1 |
| Wichser, J | 1 |
| Kazemi, H | 2 |
| Gofferje, H | 1 |
| Nierle, G | 1 |
| Chesney, RW | 1 |
| McPherson, E | 1 |
| Hall, D | 1 |
| Segar, WE | 1 |
| Quintanilla, AP | 1 |
| Sahai, A | 1 |
| Laughrey, E | 1 |
| Brackett, NC | 1 |
| Campbell, AG | 1 |
| Rosenberg, LE | 1 |
| Snodgrass, PJ | 1 |
| Nuzum, CT | 1 |
| Shore, NS | 1 |
| Shih, VE | 1 |
| Shannon, DC | 1 |
| Leveen, HH | 1 |
| Falk, G | 1 |
| Borek, B | 1 |
| Diaz, C | 1 |
| Lynfield, Y | 1 |
| Wynkoop, BJ | 1 |
| Mabunda, GA | 1 |
| Rubricius, JL | 1 |
| Christoudias, GC | 1 |
| Hindfelt, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Crossover Study of Sodium Phenylbutyrate and Low-Dose Arginine Compared to High-Dose Arginine Alone on Liver Function, Ureagenesis and Subsequent Nitric Oxide Production in Patients With Argininosuccinic Aciduria[NCT00345605] | Phase 2 | 12 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | micromoles/L (Median) |
|---|---|
| High-dose Arginine Alone | 129 |
| Low-dose Arginine Plus Buphenyl | 53 |
(NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | micromole/l (Median) |
|---|---|
| High-dose Arginine Alone | 69 |
| Low-dose Arginine Plus Buphenyl | 53 |
The result (in seconds) for a prothrombin time performed on a normal individual will vary according to the type of analytical system employed. This is due to the variations between different batches of manufacturer's tissue factor used in the reagent to perform the test. The INR was devised to standardize the results. Each manufacturer assigns an ISI value (International Sensitivity Index) for any tissue factor they manufacture. The ISI value indicates how a particular batch of tissue factor compares to an international reference tissue factor. The ISI is usually between 1.0 and 2.0. The INR is the ratio of a patient's prothrombin time to a normal (control) sample, raised to the power of the ISI value for the analytical system being used. (NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | seconds (Mean) |
|---|---|
| Low-dose Arginine Plus Buphenyl | 14.2 |
| High Dose Arginine Alone | 13.8 |
(NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | micromoles/kg/hr (Mean) |
|---|---|
| High-dose Arginine Alone | 215 |
| Low-dose Arginine Plus Buphenyl | 97 |
Plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were measured. (NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | IU/L (Mean) | |
|---|---|---|
| Plasma AST | ALT | |
| High Dose Arginine Alone | 52 | 57.86 |
| Low-dose Arginine Plus Buphenyl | 36.2 | 31.7 |
Plasma levels of coagulation factors I and IX were used as measures of hepatic synthetic function since the treatment duration was short. (NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | mg/dL (Mean) | |
|---|---|---|
| I | IX | |
| High Dose Arginine Alone | 229.77 | 98.36 |
| Low-dose Arginine Plus Buphenyl | 222.22 | 105.33 |
Prothrombin time (PT) and partial thromboplastin time (PTT) were measured PT measures factors I (fibrinogen), II (prothrombin), V, VII, and X, while PTT is a performance indicator of the efficacy of the common coagulation pathways. (NCT00345605)
Timeframe: Measured after each 1-week treatment period
| Intervention | seconds (Mean) | |
|---|---|---|
| PT | PTT | |
| High Dose Arginine Alone | 13.8 | 30.98 |
| Low-dose Arginine Plus Buphenyl | 14.25 | 30.91 |
3 reviews available for ammonium hydroxide and Alkalosis, Respiratory
| Article | Year |
|---|---|
Urea cycle disorders: diagnosis, pathophysiology, and therapy.
Topics: Adolescent; Algorithms; Alkalosis, Respiratory; Amino Acid Metabolism, Inborn Errors; Ammonia; Child | 1996 |
Urea cycle disorders: clinical paradigm of hyperammonemic encephalopathy.
Topics: Adult; Alkalosis, Respiratory; Ammonia; Brain Diseases; Brain Edema; Diagnosis, Differential; Female | 1995 |
An approach to clinical disorders of acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Ammonia; | 1974 |
14 other studies available for ammonium hydroxide and Alkalosis, Respiratory
| Article | Year |
|---|---|
[Hyperammonemic encephalopathy in multiple myeloma].
Topics: Alkalosis, Respiratory; Ammonia; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethason | 2014 |
Respiratory alkalosis in hepatic coma.
Topics: Alkalosis; Alkalosis, Respiratory; Ammonia; Blood; Hepatic Encephalopathy; Humans; Liver Diseases | 1956 |
Response of ammoniagenesis to acute alkalosis.
Topics: Acute Disease; Alkalosis; Alkalosis, Respiratory; Ammonia; Animals; Hydrogen-Ion Concentration; Kidn | 1984 |
Renal metabolism and ammoniagenesis during acute respiratory alkalosis in the dog.
Topics: Acute Disease; Alkalosis, Respiratory; Ammonia; Animals; Dogs; Female; Glomerular Filtration Rate; G | 1984 |
Effects of acute acid-base changes on in vivo total ammonia synthesis in the rat.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalosis; Alkalosis, Respirato | 1982 |
CSF bicarbonate regulation in respiratory acidosis and alkalosis.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Ammonia; Ammoni | 1975 |
[Acid-base equilibrium- -disorders and therapy].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Adrenal Insufficiency; Alkalosis, Respirator | 1975 |
Letter: Severe mixed metabolic and respiratory alkalosis in Reye syndrome.
Topics: Alkalosis; Alkalosis, Respiratory; Ammonia; Bicarbonates; Brain Diseases; Carbon Dioxide; Child, Pre | 1976 |
Acute acid-base disorders. 2. Specific disturbances.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalies; Alkalosis; Alkalosis, | 1976 |
Relationship between intracellular pH and ammonia metabolism in LLC-PK1 cells.
Topics: Acidosis; Acidosis, Respiratory; Alanine; Alkalosis; Alkalosis, Respiratory; Ammonia; Cell Line; Cyt | 1990 |
Ornithine transcarbamylase deficiency: a cause of lethal neonatal hyperammonemia in males.
Topics: Alkalosis, Respiratory; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Blood Urea Nitro | 1973 |
Brain organic buffers in respiratory acidosis and alkalosis.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Ammonia; Animals; B | 1973 |
Chemical acidification of wounds. An adjuvant to healing and the unfavorable action of alkalinity and ammonia.
Topics: Alkalies; Alkalosis, Respiratory; Ammonia; Animals; Carbon Dioxide; Dogs; Hemoglobins; Humans; Hydro | 1973 |
The effect of acute hypocapnia upon the energy state of the brain in sustained hyperammonemia.
Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Ammonia; Animals; Bicarbonates; Blood; Brain; Carbon | 1973 |