ammonium hydroxide has been researched along with Acute Lymphoid Leukemia in 14 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperammonemia has been reported following asparaginase administration, consistent with the mechanisms of asparaginase, which catabolizes asparagine to aspartic acid and ammonia, and secondarily converts glutamine to glutamate and ammonia." | 4.31 | Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia. ( Altintas, B; Eldem, I; Langley, R; Lee, A; Nguyen, H; Shinawi, M; Willis, D, 2023) |
| "Patients with acute lymphoblastic leukemia (ALL), who develop antiasparaginase antibodies without clinical allergic reactions ("silent inactivation") during L: -asparaginase (L: -Asp) treatment, have poor outcomes." | 2.74 | The ex vivo production of ammonia predicts L-asparaginase biological activity in children with acute lymphoblastic leukemia. ( Hasegawa, D; Hirabayashi, S; Hosoya, R; Inoue, T; Kizu, J; Machida, R; Manabe, A; Matsumoto, H; Miyake, K; Ogawa, C; Ohara, A; Watanabe, S; Yoshida, K, 2009) |
| "A group of 87 patients with acute lymphoblastic leukemia treated in the Department of Pediatric Oncology and Hematology in Krakow was enrolled to the study." | 1.40 | Clinical utility of ammonia concentration as a diagnostic test in monitoring of the treatment with L-asparaginase in children with acute lymphoblastic leukemia. ( Balwierz, W; Czogała, M; Rogatko, I; Sztefko, K, 2014) |
| "Of the 23 patients studied, 3 developed hepatic encephalopathy." | 1.39 | [Analysis of L-asparaginase induced elevation of blood ammonia and hepatic encephalopathy]. ( Cen, XN; Li, Y; Liang, ZY; Ren, HY; Yin, Y, 2013) |
| "The standard treatment protocol for acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) in childhood includes intravenous therapy with asparaginase (Asp), which may cause hyperammonemia." | 1.37 | Transient hyperammonemia due to L-asparaginase therapy in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma. ( Beblo, S; Bierbach, U; Jörck, C; Kiess, W; Mütze, U; Weigel, JF, 2011) |
| "One day after admission, she developed hepatic encephalopathy with ammonia concentrations in plasma >100 micromol/l." | 1.35 | Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia. ( Dada, R; Galm, O; Gassler, N; Jost, E; Osieka, R; Wilop, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Buddington, RK | 1 |
| Buddington, KK | 1 |
| Howard, SC | 1 |
| Lee, A | 1 |
| Eldem, I | 1 |
| Altintas, B | 1 |
| Nguyen, H | 1 |
| Willis, D | 1 |
| Langley, R | 1 |
| Shinawi, M | 1 |
| Gallin, M | 1 |
| Damaj, L | 1 |
| Gandemer, V | 1 |
| Bendavid, C | 1 |
| Moreau, C | 1 |
| Muneer, F | 1 |
| Siddique, MH | 1 |
| Azeem, F | 1 |
| Rasul, I | 1 |
| Muzammil, S | 1 |
| Zubair, M | 1 |
| Afzal, M | 1 |
| Nadeem, H | 1 |
| Santos, AC | 1 |
| Land, MGP | 1 |
| Lima, EC | 1 |
| Li, Y | 1 |
| Ren, HY | 1 |
| Cen, XN | 1 |
| Yin, Y | 1 |
| Liang, ZY | 1 |
| Czogała, M | 1 |
| Balwierz, W | 1 |
| Sztefko, K | 1 |
| Rogatko, I | 1 |
| Tong, WH | 1 |
| Pieters, R | 1 |
| van der Sluis, IM | 1 |
| Watanabe, S | 1 |
| Miyake, K | 1 |
| Ogawa, C | 1 |
| Matsumoto, H | 1 |
| Yoshida, K | 1 |
| Hirabayashi, S | 1 |
| Hasegawa, D | 1 |
| Inoue, T | 1 |
| Kizu, J | 1 |
| Machida, R | 1 |
| Ohara, A | 1 |
| Hosoya, R | 1 |
| Manabe, A | 1 |
| Dada, R | 1 |
| Wilop, S | 1 |
| Jost, E | 1 |
| Galm, O | 1 |
| Gassler, N | 1 |
| Osieka, R | 1 |
| Jörck, C | 1 |
| Kiess, W | 1 |
| Weigel, JF | 1 |
| Mütze, U | 1 |
| Bierbach, U | 1 |
| Beblo, S | 1 |
| Sudour, H | 1 |
| Schmitt, C | 1 |
| Contet, A | 1 |
| Chastagner, P | 1 |
| Feillet, F | 1 |
| Steiner, M | 1 |
| Attarbaschi, A | 1 |
| Kastner, U | 1 |
| Dworzak, M | 1 |
| Haas, OA | 1 |
| Gadner, H | 1 |
| Mann, G | 1 |
| Xu, SR | 1 |
| Yao, EG | 1 |
| Dong, ZR | 1 |
| Liu, RS | 1 |
| Pan, L | 1 |
| Lin, FR | 1 |
| Zhang, RX | 1 |
| Liu, MC | 1 |
| Ma, BB | 1 |
| Yin, JQ | 1 |
2 reviews available for ammonium hydroxide and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
[Molecular basis of hyperammonemia secondary to asparaginase: from therapeutic efficacity to toxicity].
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Humans; Hyperammonemia; Precursor Cell Lymphoblastic L | 2023 |
Microbial L-asparaginase: purification, characterization and applications.
Topics: Ammonia; Asparaginase; Asparagine; Aspartic Acid; Bacteria; Fungi; Hodgkin Disease; Humans; Phylogen | 2020 |
2 trials available for ammonium hydroxide and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
The ex vivo production of ammonia predicts L-asparaginase biological activity in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Biomarkers; Child; Child, Preschool; Drug Monitoring; | 2009 |
Distinct fluctuations of ammonia levels during asparaginase therapy for childhood acute leukemia.
Topics: Adolescent; Ammonia; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Drug Monitoring; | 2007 |
10 other studies available for ammonium hydroxide and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Multiple Asparaginase Infusions Cause Increasingly Severe Acute Hyperammonemia.
Topics: Ammonia; Animals; Antineoplastic Agents; Asparaginase; Hyperammonemia; Precursor Cell Lymphoblastic | 2022 |
Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Glutamine; Humans; Hyperammonemia; Phenylbutyra | 2023 |
Ammonia level as a proxy of asparaginase inactivation in children: A strategy for classification of infusion reactions.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Drug Hypersensitivity; Humans; Hyperammonemia; | 2022 |
[Analysis of L-asparaginase induced elevation of blood ammonia and hepatic encephalopathy].
Topics: Adolescent; Adult; Aged; Ammonia; Asparaginase; Female; Hepatic Encephalopathy; Humans; Male; Middle | 2013 |
Clinical utility of ammonia concentration as a diagnostic test in monitoring of the treatment with L-asparaginase in children with acute lymphoblastic leukemia.
Topics: Adolescent; Ammonia; Asparaginase; Child; Child, Preschool; Diagnostic Tests, Routine; Female; Human | 2014 |
Ammonia Levels Should Not Be Used as a Surrogate Marker of Levels of Asparaginase Activity in Acute Lymphoblastic Leukemia Patients.
Topics: Ammonia; Asparaginase; Biomarkers; Child; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pr | 2016 |
Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia.
Topics: Adult; Alanine Transaminase; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Aspartate Amin | 2009 |
Transient hyperammonemia due to L-asparaginase therapy in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Topics: Adolescent; Ammonia; Antineoplastic Agents; Asparaginase; Child; Female; Humans; Hyperammonemia; Lym | 2011 |
Acute metabolic encephalopathy in two patients treated with asparaginase and ondasetron.
Topics: Adolescent; Ammonia; Asparaginase; Brain Diseases, Metabolic; Humans; Male; Precursor Cell Lymphobla | 2011 |
Plasma ammonia in patients with acute leukemia.
Topics: Adolescent; Adult; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia | 1992 |