ammonium hydroxide has been researched along with Acute Liver Injury, Drug-Induced in 87 studies
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Further research should be conducted into the prevalence and pathophysiology of methamphetamine-induced encephalopathy in the absence of hyperammonemia." | 8.31 | Methamphetamine-induced encephalopathy in the absence of hyperammonemia. ( Bowman, J; Dong, F; Fitzgerald, K; Neeki, MM; Rabbany, JM, 2023) |
| "This study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy." | 7.88 | Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy. ( Li, X; Zhang, T; Zhao, L; Zhu, X, 2018) |
| "In November 1996, a panel of pediatric neurologists met to update the consensus statement issued in 1989 by a panel of neurologists and metabolic experts on L-carnitine supplementation in childhood epilepsy." | 7.70 | L-carnitine supplementation in childhood epilepsy: current perspectives. ( Bohan, TP; Coulter, DL; De Vivo, DC; Dreifuss, FE; Greenwood, RS; Nordli, DR; Shields, WD; Stafstrom, CE; Tein, I, 1998) |
| "Hepatic encephalopathy in patients with severe liver disease was associated with marked elevation of either serum methionine or blood ammonia levels or with simultaneous moderate increases in both parameters." | 7.66 | Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy. ( Higashi, T, 1982) |
| " One of the biggest problems of these compounds, however, is their very short bioavailability due to instant metabolism and rapid excretion." | 5.51 | Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury. ( Ibayashi, Y; Lee, Y; Nagasaki, Y; Ngo, DN; Nishikawa, Y; Vong, LB, 2019) |
| "Further research should be conducted into the prevalence and pathophysiology of methamphetamine-induced encephalopathy in the absence of hyperammonemia." | 4.31 | Methamphetamine-induced encephalopathy in the absence of hyperammonemia. ( Bowman, J; Dong, F; Fitzgerald, K; Neeki, MM; Rabbany, JM, 2023) |
| "This study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy." | 3.88 | Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy. ( Li, X; Zhang, T; Zhao, L; Zhu, X, 2018) |
| "Amiodarone is commonly used in the treatment of refractory paroxysmal atrial fibrillation." | 3.76 | Hepatic dysfunction and neurotoxicity in a patient receiving long-term low-dose amiodarone therapy. ( Arkun, A; Birkhahn, RH; Grau, T; Van Deusen, SK, 2010) |
| "In November 1996, a panel of pediatric neurologists met to update the consensus statement issued in 1989 by a panel of neurologists and metabolic experts on L-carnitine supplementation in childhood epilepsy." | 3.70 | L-carnitine supplementation in childhood epilepsy: current perspectives. ( Bohan, TP; Coulter, DL; De Vivo, DC; Dreifuss, FE; Greenwood, RS; Nordli, DR; Shields, WD; Stafstrom, CE; Tein, I, 1998) |
| "Hepatic encephalopathy in patients with severe liver disease was associated with marked elevation of either serum methionine or blood ammonia levels or with simultaneous moderate increases in both parameters." | 3.66 | Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy. ( Higashi, T, 1982) |
| "Valproic acid (VPA) is an anti-seizure drug that causes idiosyncratic liver injury." | 2.82 | Valproic acid induced liver injury: An insight into molecular toxicological mechanism. ( Ezhilarasan, D; Mani, U, 2022) |
| "Acute liver failure is a rare disorder with high mortality and resource cost." | 2.46 | Acute liver failure. ( Auzinger, G; Bernal, W; Dhawan, A; Wendon, J, 2010) |
| "Carnitine is an essential amino acid necessary in beta-oxidation of fatty acids and energy production in cellular mitochondria." | 2.41 | The role of carnitine supplementation during valproic acid therapy. ( El-Chaar, GM; Raskind, JY, 2000) |
| " These deal mainly with biochemical systems that are known to be affected by VPA, or with the possible idiosyncratic production of toxic VPA metabolites, especially delta 4-VPA." | 2.38 | Valproate hepatotoxicity syndrome: hypotheses of pathogenesis. ( Levy, RH; Stephens, JR, 1992) |
| " One of the biggest problems of these compounds, however, is their very short bioavailability due to instant metabolism and rapid excretion." | 1.51 | Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury. ( Ibayashi, Y; Lee, Y; Nagasaki, Y; Ngo, DN; Nishikawa, Y; Vong, LB, 2019) |
| " Microfluidic bioartificial organs enable the spatial and temporal control of cell growth and biochemistry, critical for organ-specific metabolic functions and particularly relevant to testing the metabolic dose-response signatures associated with both pharmaceutical and environmental toxicity." | 1.38 | Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs. ( Baudoin, R; Blaise, BJ; Brochot, C; Defernez, M; Domange, C; Dumas, ME; Leclerc, E; Legallais, C; Navratil, V; Péry, AR; Pontoizeau, C; Prot, JM; Shintu, L; Toulhoat, P, 2012) |
| "Treatment with melatonin (3 mg/kg/daily, i." | 1.32 | Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats. ( Aeed, H; Avinoach, I; Avni, Y; Bruck, R; Hochman, A; Matas, Z; Shahmurov, M; Shirin, H; Weizman, N; Zozulya, G, 2004) |
| "In 37 women with long-term use of oral contraceptives (average use 13." | 1.28 | [Use of the stable nitrogen isotope 15N in assessing liver metabolism in hormonal contraception]. ( Graubaum, HJ; Jung, K; Kranz, D; Laue, R; Metzner, C; Seifert, P; Wagenknecht, C, 1990) |
| " In the two cases presented there was a severe outbreak of hepatotoxic encephalopathy despite the fact that the dosage of salicylates did not exceed that generally recommended for children with rheumatic diseases." | 1.26 | Toxic encephalopathy with hyperammonaemia during high-dose salicylate therapy. ( Korpela, P; Lang, H; Mäkelä, AL, 1980) |
| "3." | 1.25 | Exchange transfusion in hepatic coma: factors affecting results, with long-term follow-up data. ( Darin, JC; Hussey, CV; Lewis, JD; Varma, RR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (55.17) | 18.7374 |
| 1990's | 9 (10.34) | 18.2507 |
| 2000's | 9 (10.34) | 29.6817 |
| 2010's | 16 (18.39) | 24.3611 |
| 2020's | 5 (5.75) | 2.80 |
| Authors | Studies |
|---|---|
| Ezhilarasan, D | 1 |
| Mani, U | 1 |
| Rabbany, JM | 1 |
| Fitzgerald, K | 1 |
| Bowman, J | 1 |
| Dong, F | 1 |
| Neeki, MM | 1 |
| Yan, Z | 1 |
| Wan, J | 1 |
| Liu, J | 1 |
| Yao, B | 1 |
| Lu, Y | 1 |
| Guo, Z | 1 |
| Li, Y | 1 |
| Vong, LB | 1 |
| Ibayashi, Y | 1 |
| Lee, Y | 1 |
| Ngo, DN | 1 |
| Nishikawa, Y | 1 |
| Nagasaki, Y | 1 |
| Yan, T | 1 |
| Li, F | 1 |
| Xiong, W | 1 |
| Wu, B | 1 |
| Xiao, F | 1 |
| He, B | 1 |
| Jia, Y | 1 |
| Hamdani, EH | 1 |
| Popek, M | 1 |
| Frontczak-Baniewicz, M | 1 |
| Utheim, TP | 1 |
| Albrecht, J | 3 |
| Zielińska, M | 1 |
| Chaudhry, FA | 1 |
| Zhu, X | 1 |
| Li, X | 1 |
| Zhang, T | 1 |
| Zhao, L | 1 |
| Chien, MM | 1 |
| Chang, MH | 1 |
| Chang, KC | 1 |
| Lu, FT | 1 |
| Chiu, YC | 1 |
| Chen, HL | 1 |
| Ni, YH | 1 |
| Hsu, HY | 1 |
| Wu, JF | 1 |
| Jung, E | 1 |
| Kim, J | 1 |
| Stenbøg, P | 1 |
| Busk, T | 1 |
| Larsen, FS | 1 |
| Blanco, VM | 1 |
| Márquez, MS | 1 |
| Alvarez-Leefmans, FJ | 1 |
| Vargha, R | 1 |
| Mostafa, G | 1 |
| Burda, G | 1 |
| Hermon, M | 1 |
| Trittenwein, G | 1 |
| Gole, J | 1 |
| Shimizu, D | 1 |
| Ishitsuka, Y | 1 |
| Miyata, K | 1 |
| Tomishima, Y | 1 |
| Kondo, Y | 1 |
| Irikura, M | 1 |
| Iwawaki, T | 1 |
| Oike, Y | 1 |
| Irie, T | 1 |
| Shen, TC | 1 |
| Albenberg, L | 1 |
| Bittinger, K | 1 |
| Chehoud, C | 1 |
| Chen, YY | 1 |
| Judge, CA | 1 |
| Chau, L | 1 |
| Ni, J | 1 |
| Sheng, M | 1 |
| Lin, A | 1 |
| Wilkins, BJ | 1 |
| Buza, EL | 1 |
| Lewis, JD | 2 |
| Daikhin, Y | 1 |
| Nissim, I | 1 |
| Yudkoff, M | 1 |
| Bushman, FD | 1 |
| Wu, GD | 1 |
| Benli, AC | 1 |
| Köksal, G | 1 |
| Ozkul, A | 1 |
| Arkun, A | 1 |
| Van Deusen, SK | 1 |
| Grau, T | 1 |
| Birkhahn, RH | 1 |
| Chen, YR | 1 |
| Sekine, K | 1 |
| Nakamura, K | 1 |
| Yanai, H | 1 |
| Tanaka, M | 1 |
| Miyajima, A | 1 |
| Kaminsky, Y | 1 |
| Kosenko, E | 1 |
| Bernal, W | 1 |
| Auzinger, G | 1 |
| Dhawan, A | 1 |
| Wendon, J | 1 |
| Shintu, L | 1 |
| Baudoin, R | 1 |
| Navratil, V | 1 |
| Prot, JM | 1 |
| Pontoizeau, C | 1 |
| Defernez, M | 1 |
| Blaise, BJ | 1 |
| Domange, C | 1 |
| Péry, AR | 1 |
| Toulhoat, P | 1 |
| Legallais, C | 1 |
| Brochot, C | 1 |
| Leclerc, E | 1 |
| Dumas, ME | 1 |
| Obara-Michlewska, M | 1 |
| Tuszyńska, P | 1 |
| Krauss, M | 1 |
| Schaller, S | 1 |
| Borchers, S | 1 |
| Findeisen, R | 1 |
| Lippert, J | 1 |
| Kuepfer, L | 1 |
| Dai, MZ | 1 |
| Lin, YL | 1 |
| Lin, HC | 1 |
| Zan, HW | 1 |
| Chang, KT | 1 |
| Meng, HF | 1 |
| Liao, JW | 1 |
| Tsai, MJ | 1 |
| Cheng, H | 1 |
| PILGERSTORFER, W | 1 |
| SOBERON, G | 1 |
| FLORES, G | 1 |
| ROSADO, A | 1 |
| TORRES GALLARDO, J | 1 |
| MORA, J | 1 |
| MAGGIO, R | 1 |
| DIENST, SG | 1 |
| GIULIANI, V | 1 |
| MASUDA, M | 1 |
| KUZUDANI, A | 1 |
| MORI, K | 1 |
| OGASAWARA, K | 1 |
| IRINO, J | 1 |
| TABUCHI, K | 1 |
| TOMIKAWA, J | 1 |
| INOUE, H | 1 |
| NAKANO, K | 1 |
| ADACHI, H | 1 |
| KANETSUNA, H | 1 |
| MONDEN, M | 1 |
| SHIOYA, A | 1 |
| KURAISHI, K | 1 |
| KAKIMOTO, M | 1 |
| TAMAMA, Y | 1 |
| SALVATORE, F | 1 |
| CIMINO, F | 1 |
| DAYELLO CARACCIOLO, M | 1 |
| CITTADINI, D | 1 |
| KOWALEWSKI, K | 3 |
| SEIDLER, E | 1 |
| THIELE, W | 1 |
| BARAONA, E | 1 |
| SALINAS, A | 1 |
| NAVIA, E | 1 |
| ORREGO, H | 1 |
| CORNELIUS, CE | 2 |
| GAZMURI, G | 1 |
| GRONWALL, R | 1 |
| RHODE, EA | 1 |
| Bruck, R | 1 |
| Aeed, H | 1 |
| Avni, Y | 1 |
| Shirin, H | 1 |
| Matas, Z | 1 |
| Shahmurov, M | 1 |
| Avinoach, I | 1 |
| Zozulya, G | 1 |
| Weizman, N | 1 |
| Hochman, A | 1 |
| Kuhrt, H | 1 |
| Walski, M | 1 |
| Reichenbach, A | 1 |
| Túnez, I | 1 |
| Muñoz, MC | 1 |
| Villavicencio, MA | 1 |
| Medina, FJ | 1 |
| de Prado, EP | 1 |
| Espejo, I | 1 |
| Barcos, M | 1 |
| Salcedo, M | 1 |
| Feijóo, M | 1 |
| Montilla, P | 1 |
| Nishida, T | 1 |
| Matsura, T | 1 |
| Nakada, J | 1 |
| Togawa, A | 1 |
| Kai, M | 1 |
| Sumioka, I | 1 |
| Minami, Y | 1 |
| Inagaki, Y | 1 |
| Ishibe, Y | 1 |
| Ito, H | 1 |
| Ohta, Y | 1 |
| Yamada, K | 1 |
| Hamid, HA | 1 |
| El-Gazzar, RM | 1 |
| Harputluoglu, MM | 1 |
| Demirel, U | 1 |
| Ciralik, H | 1 |
| Temel, I | 1 |
| Firat, S | 1 |
| Ara, C | 1 |
| Aladag, M | 1 |
| Karincaoglu, M | 1 |
| Hilmioglu, F | 1 |
| Goto, S | 1 |
| Seo, T | 1 |
| Hagiwara, T | 1 |
| Ueda, K | 1 |
| Yamauchi, T | 1 |
| Nagata, S | 1 |
| Ando, Y | 1 |
| Ishitsu, T | 1 |
| Nakagawa, K | 1 |
| Strolin Benedetti, M | 1 |
| Rumigny, JF | 1 |
| Dostert, P | 1 |
| Sakai, T | 1 |
| Powell-Jackson, PR | 1 |
| Tredger, JM | 1 |
| Williams, R | 1 |
| Häussinger, D | 1 |
| Gerok, W | 1 |
| Faus, MJ | 1 |
| Pita, ML | 1 |
| Lupiánez, JA | 1 |
| Hortelano, P | 1 |
| Sánchez-Medina, F | 1 |
| O'Donovan, DJ | 1 |
| Higashi, T | 1 |
| Mäkelä, AL | 1 |
| Lang, H | 1 |
| Korpela, P | 1 |
| Ozretić, B | 1 |
| Krajnović-Ozretić, M | 1 |
| Böhles, H | 1 |
| Sewell, AC | 1 |
| Wenzel, D | 1 |
| Valik, D | 1 |
| De Vivo, DC | 1 |
| Bohan, TP | 1 |
| Coulter, DL | 1 |
| Dreifuss, FE | 1 |
| Greenwood, RS | 1 |
| Nordli, DR | 1 |
| Shields, WD | 1 |
| Stafstrom, CE | 1 |
| Tein, I | 1 |
| Raskind, JY | 1 |
| El-Chaar, GM | 1 |
| Maestracci, P | 1 |
| Grimaud, D | 1 |
| Madani, MO | 1 |
| Adam, SE | 1 |
| Himes, JA | 1 |
| Gronwall, RR | 1 |
| Hussey, CV | 1 |
| Varma, RR | 1 |
| Darin, JC | 1 |
| Kisfaludy, S | 1 |
| Stephens, JR | 1 |
| Levy, RH | 1 |
| Seiler, N | 1 |
| Sarhan, S | 1 |
| Knödgen, B | 1 |
| Wiedemann, G | 1 |
| Haupt, M | 1 |
| Rommel, A | 1 |
| Rommel, KF | 1 |
| Biesenbach, R | 1 |
| Schmidt, W | 1 |
| Metzner, C | 1 |
| Jung, K | 1 |
| Laue, R | 1 |
| Wagenknecht, C | 1 |
| Graubaum, HJ | 1 |
| Kranz, D | 1 |
| Seifert, P | 1 |
| Kamei, S | 1 |
| Zieve, L | 2 |
| Morimoto, Y | 1 |
| Ukida, M | 1 |
| Tsuji, T | 1 |
| Grüngreiff, K | 1 |
| Abicht, K | 1 |
| Kluge, M | 1 |
| Presser, HJ | 1 |
| Franke, D | 1 |
| Kleine, FD | 1 |
| Klauck, S | 1 |
| Diete, U | 1 |
| Anderson, WR | 1 |
| LaFontaine, D | 1 |
| Ito, M | 1 |
| Matsumoto, H | 1 |
| Kikuchi, S | 1 |
| Yachi, A | 1 |
| Schrader, A | 1 |
| Staeffen, J | 1 |
| Oberling, F | 1 |
| Cazenave, JP | 1 |
| Lang, JM | 1 |
| Kurtz, D | 1 |
| Mayer, G | 1 |
| Waitz, R | 1 |
| Hsia, YE | 1 |
| Róka, L | 1 |
| Miertsch, HJ | 1 |
| Zamora, AJ | 1 |
| Cavanagh, JB | 1 |
| Kyu, MH | 1 |
| Parkins, JJ | 1 |
| Hemingway, RG | 1 |
| Brown, NA | 1 |
| Hooper, PT | 1 |
| Best, SM | 1 |
| Murray, DR | 1 |
| Zuidema, GD | 1 |
| Kirsh, MM | 1 |
| Gaisford, WD | 1 |
| Trey, C | 1 |
| Garcia, FG | 1 |
| King, NW | 1 |
| Lowenstein, LM | 1 |
| Davidson, CS | 1 |
| Szelenyi, I | 1 |
| Farkas, I | 1 |
| Desi, I | 1 |
| Nemesánszky, E | 1 |
| Michalowicz-Wojczyńska, E | 1 |
| Hourani, BT | 1 |
| Hamlin, EM | 1 |
| Reynolds, TB | 1 |
| Di Rosa, M | 1 |
| Weisberg, H | 1 |
| Strobos, RJ | 1 |
| Rosenthal, WS | 1 |
| Appleton, HD | 1 |
| Glass, GB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Steroids in the Management of Fulminant Hepatic Failure Due to Hepatitis A Virus in the Pediatric Age Group[NCT02375867] | Phase 4 | 33 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for ammonium hydroxide and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Valproic acid induced liver injury: An insight into molecular toxicological mechanism.
Topics: Adenosine Triphosphate; Ammonia; Anticonvulsants; Carnitine O-Palmitoyltransferase; Chemical and Dru | 2022 |
Efficacy of liver assisting in patients with hepatic encephalopathy with special focus on plasma exchange.
Topics: Ammonia; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Humans; Liver Failure; Live | 2013 |
Acute liver failure.
Topics: Acetaminophen; Ammonia; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Emergency | 2010 |
[Mechanisms of action and biochemical toxicology of valproic acid].
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Ammonia; Animals; Anticonvulsants; Aspartic | 1984 |
[Clinical study on therapeutic plasmapheresis--mechanism of its efficacy, indications, and the clinical application. e. Liver failure].
Topics: Amino Acids; Ammonia; Chemical and Drug Induced Liver Injury; Evaluation Studies as Topic; Humans; L | 1984 |
Hepatotoxicity to sodium valproate: a review.
Topics: Adolescent; Adult; Ammonia; Animals; Chemical and Drug Induced Liver Injury; Child; Child, Preschool | 1984 |
The role of carnitine supplementation during valproic acid therapy.
Topics: Adolescent; Adult; Aged; Ammonia; Anticonvulsants; Carnitine; Chemical and Drug Induced Liver Injury | 2000 |
Experimental liver diseases.
Topics: Alkaloids; Ammonia; Animals; Bilirubin; Budd-Chiari Syndrome; Carbon Tetrachloride Poisoning; Cattle | 1975 |
Valproate hepatotoxicity syndrome: hypotheses of pathogenesis.
Topics: Ammonia; Animals; Carnitine; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Diseases; | 1992 |
Inherited hyperammonemic syndromes.
Topics: Acidosis; Amino Acids; Ammonia; Animals; Arginine; Brain; Brain Diseases; Chemical and Drug Induced | 1974 |
Hepatic encephalopathy.
Topics: Ammonia; Animals; Anti-Bacterial Agents; Arginine; Chemical and Drug Induced Liver Injury; Colectomy | 1964 |
2 trials available for ammonium hydroxide and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Potential relationships between transaminase abnormality and valproic acid clearance or serum carnitine concentrations in Japanese epileptic patients.
Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Body Weight; Carnitine; Chemical and Drug Induced Liver | 2008 |
The effect of carnitine supplementation in valproate-induced hyperammonaemia.
Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Carnitine; Chemical and Drug Induced Liver Injury; Chil | 1996 |
74 other studies available for ammonium hydroxide and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Methamphetamine-induced encephalopathy in the absence of hyperammonemia.
Topics: Ammonia; Brain Diseases; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adver | 2023 |
α-lipoic acid ameliorates hepatotoxicity induced by chronic ammonia toxicity in crucian carp (Carassius auratus gibelio) by alleviating oxidative stress, inflammation and inhibiting ERS pathway.
Topics: Ammonia; Animals; Antioxidants; Carps; Chemical and Drug Induced Liver Injury; Goldfish; Humans; Inf | 2023 |
Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury.
Topics: Acetaminophen; Ammonia; Animals; Cattle; Cell Survival; Chemical and Drug Induced Liver Injury; Chon | 2019 |
Nootkatone improves anxiety- and depression-like behavior by targeting hyperammonemia-induced oxidative stress in D-galactosamine model of liver injury.
Topics: Ammonia; Animals; Antidepressive Agents; Antioxidants; Anxiety; Behavior, Animal; Brain; Cell Surviv | 2021 |
Perturbation of astroglial Slc38 glutamine transporters by NH
Topics: Amino Acid Transport Systems, Neutral; Ammonia; Animals; Astrocytes; Azoxymethane; Brain Edema; Cere | 2021 |
Risk Factors for Valproic Acid-induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy.
Topics: Age Factors; Ammonia; Anticonvulsants; Aspartate Aminotransferases; Chemical and Drug Induced Liver | 2018 |
Prognostic parameters of pediatric acute liver failure and the role of plasma exchange.
Topics: Adolescent; alpha-Fetoproteins; Ammonia; Antithyroid Agents; Chemical and Drug Induced Liver Injury; | 2019 |
Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy.
Topics: Ammonia; Animals; Aquaporin 4; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Emodi | 2018 |
Parallel changes in intracellular water volume and pH induced by NH(3)/NH(4)(+) exposure in single neuroblastoma cells.
Topics: Ammonia; Ammonium Compounds; Biological Transport; Brain Edema; Cell Size; Chemical and Drug Induced | 2013 |
Treatment with N-acetylcystein and total plasma exchange for extracorporeal liver support in children with paracetamol intoxication.
Topics: Acetaminophen; Acetylcysteine; Ammonia; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver In | 2014 |
Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
Topics: Acetaminophen; Alanine Transaminase; Ammonia; Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Pro | 2014 |
Engineering the gut microbiota to treat hyperammonemia.
Topics: Ammonia; Animals; Bacteria; Bacterial Proteins; Bioengineering; Biological Therapy; Chemical and Dru | 2015 |
Sublethal ammonia exposure of Nile tilapia (Oreochromis niloticus L.): effects on gill, liver and kidney histology.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Cichlids; Gills; Glomerulonephritis; Hydro | 2008 |
Hepatic dysfunction and neurotoxicity in a patient receiving long-term low-dose amiodarone therapy.
Topics: Aged, 80 and over; Amiodarone; Ammonia; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Dr | 2010 |
Y-box binding protein-1 down-regulates expression of carbamoyl phosphate synthetase-I by suppressing CCAAT enhancer-binding protein-alpha function in mice.
Topics: Age Factors; Ammonia; Animals; Animals, Newborn; Base Sequence; Carbamoyl-Phosphate Synthase (Ammoni | 2009 |
AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis.
Topics: Acute Disease; Adenine Nucleotides; Adenosine Deaminase; Ammonia; AMP Deaminase; Animals; Brain; Car | 2010 |
Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs.
Topics: Acetaminophen; Ammonia; Analgesics, Non-Narcotic; Animals; Bioartificial Organs; Cells, Cultured; Ch | 2012 |
Ammonia upregulates kynurenine aminotransferase II mRNA expression in rat brain: a role for astrocytic NMDA receptors?
Topics: Ammonia; Analysis of Variance; Animals; Astrocytes; Brain Chemistry; Carcinogens; Chemical and Drug | 2013 |
Integrating cellular metabolism into a multiscale whole-body model.
Topics: Acetaminophen; Allopurinol; Ammonia; Chemical and Drug Induced Liver Injury; Computational Biology; | 2012 |
Highly sensitive ammonia sensor with organic vertical nanojunctions for noninvasive detection of hepatic injury.
Topics: Ammonia; Animals; Breath Tests; Chemical and Drug Induced Liver Injury; Female; Nanostructures; Rats | 2013 |
[Toxic hepatosis in ammonia poisoning].
Topics: Ammonia; Chemical and Drug Induced Liver Injury; Hepatitis; Humans; Occupational Diseases | 1963 |
[Hyperammonemia and hepatic insufficiency].
Topics: Ammonia; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; He | 1963 |
TREATMENT OF PROGRESSIVE AMMONIA INTOXICATION BY EXCLUSION OF THE COLON.
Topics: Ammonia; Blood; Chemical and Drug Induced Liver Injury; Colon; Hepatic Encephalopathy; Hepatitis; Po | 1964 |
[INITIAL CLINICAL RESULTS FOLLOWING THE USE OF A NEW HEPATOPROTECTIVE AND ANTI-BLOOD AMMONIA PREPARATION].
Topics: Amino Acids; Ammonia; Arginine; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Cit | 1963 |
[STUDIES ON ASPARTIC ACID SALTS. II. BASIC STUDIES].
Topics: Ammonia; Aspartic Acid; Biomedical Research; Carbon Tetrachloride Poisoning; Chemical and Drug Induc | 1964 |
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Ind | 1964 |
PHARMACOLOGICAL STUDY ON L-ORNITHINE L-ASPARTATE.
Topics: Alanine Transaminase; Ammonia; Ammonium Chloride; Aspartate Aminotransferases; Aspartic Acid; Blood; | 1964 |
MECHANISM OF THE PROTECTION BY L-ORNITHINE-L-ASPARTATE MIXTURE AND BY L-ARGININE IN AMMONIA INTOXICATION.
Topics: Ammonia; Arginine; Aspartic Acid; Chemical and Drug Induced Liver Injury; Dipeptides; Hepatitis; Lig | 1964 |
EFFECT OF ETHIONINE ON TOTAL BLOOD AMMONIA IN RATS.
Topics: Ammonia; Blood; Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Hepatitis A; Metabolis | 1965 |
BLOOD AMMONIA IN RATS WITH EXPERIMENTAL LIVER DAMAGE.
Topics: Ammonia; Antimetabolites; Blood; Chemical and Drug Induced Liver Injury; Diet; Ethionine; Fatty Live | 1965 |
[AMMONIA AND PROTEIN DETERMINATIONS IN EXPERIMENTAL PORTAL VEIN LIGATION IN RABBITS].
Topics: Ammonia; Animals; Blood Chemical Analysis; Blood Protein Electrophoresis; Chemical and Drug Induced | 1965 |
ALTERATIONS OF AMMONIA METABOLISM IN THE CEREBRAL CORTEX OF RATS WITH HEPATIC DAMAGE INDUCED BY CARBON TETRACHLORIDE.
Topics: Aminobutyrates; Ammonia; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cere | 1965 |
PRELIMINARY STUDIES ON EXPERIMENTAL HYPERBILIRUBINEMIA AND HEPATIC COMA IN THE HORSE.
Topics: Ammonia; Animals; Blood Chemical Analysis; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1965 |
Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Liver; Liver Dise | 2004 |
Rabbit retinal organ culture as an in-vitro model of hepatic retinopathy.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glial Fibrillary A | 2004 |
Hepato- and neurotoxicity induced by thioacetamide: protective effects of melatonin and dimethylsulfoxide.
Topics: Alanine Transaminase; Ammonia; Animals; Blood Urea Nitrogen; Brain; Catalase; Chemical and Drug Indu | 2005 |
Geranylgeranylacetone protects against acetaminophen-induced hepatotoxicity by inducing heat shock protein 70.
Topics: Acetaminophen; Alanine Transaminase; Ammonia; Analgesics, Non-Narcotic; Animals; Anti-Ulcer Agents; | 2006 |
Effect of occupational exposure to ammonia on enzymatic activities of catalase and mono amine oxidase.
Topics: Adult; Alanine Transaminase; Ammonia; Aspartate Aminotransferases; Blood Urea Nitrogen; Case-Control | 1996 |
Protective effects of Gingko biloba on thioacetamide-induced fulminant hepatic failure in rats.
Topics: Acetylcysteine; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Chem | 2006 |
Hepatocyte heterogeneity in ammonia metabolism: impairment of glutamine synthesis in CCl4 induced liver cell necrosis with no effect on urea synthesis.
Topics: Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Mo | 1984 |
Dissociation between renal gluconeogenesis and ammoniagenesis after acute liver intoxication.
Topics: Acidosis; Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1982 |
Hepatic glutamine synthesis and urinary ammonia excretion.
Topics: Acidosis; Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1982 |
Impaired metabolism of methionine in severe liver diseases. II. Clinical and experimental studies on role of impaired methionine metabolism in pathogenesis of hepatic encephalopathy.
Topics: Ammonia; Animals; Brain; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatic Enc | 1982 |
Toxic encephalopathy with hyperammonaemia during high-dose salicylate therapy.
Topics: Adolescent; Ammonia; Chemical and Drug Induced Liver Injury; Child; Electroencephalography; Female; | 1980 |
Plasma sorbitol dehydrogenase, glutamate dehydrogenase, and alkaline phosphatase as potential indicators of liver intoxication in grey mullet (Mugil auratus Risso).
Topics: Alkaline Phosphatase; Ammonia; Animals; Biomarkers; Carbon Tetrachloride Poisoning; Chemical and Dru | 1993 |
Encephalopathy, lactic acidosis, hyperammonaemia and 5-fluorouracil toxicity.
Topics: Acidosis, Lactic; Ammonia; Brain Diseases; Chemical and Drug Induced Liver Injury; Citric Acid Cycle | 1998 |
L-carnitine supplementation in childhood epilepsy: current perspectives.
Topics: Age Factors; Ammonia; Anticonvulsants; Carnitine; Chemical and Drug Induced Liver Injury; Child; Chi | 1998 |
[Acute hepatocellular insufficiency or severe jaundice].
Topics: Acute Disease; Ammonia; Brain Diseases, Metabolic; Chemical and Drug Induced Liver Injury; Citric Ac | 1976 |
Ligation of the bile duct and acute chloroform toxicity in the donkey.
Topics: Ammonia; Animals; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Injury; Chloroform; Cholest | 1976 |
Exchange transfusion in hepatic coma: factors affecting results, with long-term follow-up data.
Topics: Adolescent; Adult; Aged; Ammonia; Bilirubin; Biopsy; Chemical and Drug Induced Liver Injury; Child; | 1975 |
Effects of ammonia intoxication and liver injury on rat brain glutamate-dehydrogenase and glutaminase activity.
Topics: Ammonia; Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Gal | 1975 |
Inhibition of ornithine aminotransferase by 5-fluoromethylornithine: protection against acute thioacetamide intoxication by elevated tissue ornithine levels.
Topics: Amino Acids; Ammonia; Animals; Biogenic Polyamines; Chemical and Drug Induced Liver Injury; Hemorrha | 1992 |
[Incidence of pathologic ammonia concentrations in the plasma in children with seizure disorders treated with Convulsofin/Convulex and other anticonvulsants in comparison with children with brain damage and healthy children].
Topics: Adolescent; Ammonia; Anticonvulsants; Brain Damage, Chronic; Chemical and Drug Induced Liver Injury; | 1990 |
[Use of the stable nitrogen isotope 15N in assessing liver metabolism in hormonal contraception].
Topics: Adult; Ammonia; Ammonium Chloride; Chemical and Drug Induced Liver Injury; Contraceptives, Oral, Hor | 1990 |
[Clinical significance of ornithine carbamoyltransferase analysis in biochemical laboratory tests].
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Chemical and Drug Induced Liver Injury; Hepatitis, Vi | 1989 |
Regenerative enzyme activity of the liver after partial hepatectomy or toxic injury depressed by continuous NH4+ infusion.
Topics: Acetaminophen; Ammonia; Ammonium Chloride; Animals; Chemical and Drug Induced Liver Injury; Galactos | 1989 |
Dynamic relationship between urea and glutamine synthesis in the mechanism of ammonia detoxication: a tracer study using 15NH4Cl in fulminant hepatic failure rats.
Topics: Ammonia; Ammonium Chloride; Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Ga | 1988 |
Clinical studies on zinc in chronic liver diseases.
Topics: Adult; Ammonia; Chemical and Drug Induced Liver Injury; Fatty Liver, Alcoholic; Female; Hepatic Ence | 1988 |
Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat.
Topics: Ammonia; Animals; Caprylates; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Ornithin | 1988 |
[A comparative study of free amino acid levels in the serum and cerebral cortex in hepatic failure rats].
Topics: Acute Disease; Amino Acids; Ammonia; Animals; Blood-Brain Barrier; Carbon Tetrachloride; Cerebral Co | 1986 |
[Parenchymatous organs, hematopoietic system].
Topics: Ammonia; Anemia; Blood Coagulation Disorders; Brain; Brain Diseases; Brain Edema; Cerebral Hemorrhag | 1971 |
[Hepatic coma in cirrhosis].
Topics: Ammonia; Blood Transfusion; Chemical and Drug Induced Liver Injury; Chlorine; Diagnosis, Differentia | 1969 |
[Apropos of certain toxic effects of L-asparaginase in human therapy].
Topics: Acute Disease; Adult; Ammonia; Asparaginase; Asthenia; Blood Coagulation Disorders; Brain; Chemical | 1971 |
[Study on di-L(+)-ornithine-alpha-ketoglutaric acid in the model of isolated perfused rat liver].
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Female; Galactosamine; Glucose; Ketoglutar | 1972 |
Ultrastructural responses of the astrocytes to portocaval anastomosis in the rat.
Topics: Ammonia; Animals; Brain; Brain Diseases; Carbon Tetrachloride Poisoning; Caudate Nucleus; Cerebellar | 1973 |
The increasing susceptibility of sheep to dietary urea toxicity associated with progressive liver dysfunction.
Topics: Ammonia; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Ind | 1973 |
Hyperammonaemia and spongy degeneration of the brain in sheep affected with hepatic necrosis.
Topics: Ammonia; Animals; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Glutamine; Liver; L | 1974 |
Massive liver necrosis in the monkey: the effects of exchange blood transfusions on fulminant liver failure.
Topics: Ammonia; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Ind | 1969 |
[Effect of magnesium orotate glycinate on the brain electric activity after experimental ammonia poisoning].
Topics: Ammonia; Animals; Brain Diseases; Chemical and Drug Induced Liver Injury; Electroencephalography; Fe | 1971 |
Blood ammonia in portal hypertension and liver diseases in children.
Topics: Adolescent; Adult; Age Factors; Ammonia; Ammonium Chloride; Chemical and Drug Induced Liver Injury; | 1969 |
Cerebrospinal fluid glutamine as a measure of hepatic encephalopathy.
Topics: Ammonia; Brain Diseases; Chemical and Drug Induced Liver Injury; Glutamine; Humans; Liver Cirrhosis; | 1971 |
[Blood ammonia antagonistic and hepatoprotective effect of a combination of arginine, taurine and vitamin B6 pyrrolidon-carboxylate].
Topics: Ammonia; Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1967 |
Effect of a monoamine oxidase inhibitor on total blood ammonia in rats with ethionine induced liver injury.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Dietary Proteins; Ethionine; Nialamide; Ra | 1965 |
The comparative effect of chlorothiazide and meralluride on the development of hepatic encephalopathy in cirrhotic patients.
Topics: Ammonia; Bicarbonates; Blood Urea Nitrogen; Body Weight; Brain Diseases; Chemical and Drug Induced L | 1966 |