amlodipine has been researched along with Sleep Apnea, Obstructive in 7 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of chlortalidone plus amiloride and amlodipine on blood pressure (BP) variability in patients with hypertension and obstructive sleep apnea syndrome (OSA)." | 9.69 | Effects of chlorthalidone plus amiloride compared with amlodipine on short-term blood pressure variability in individuals with hypertension and obstructive sleep apnea: a randomized controlled trial. ( Borges, RB; Cichelero, FT; Fuchs, FD; Fuchs, SC; Hirakata, VN; Jorge, JA; Lucca, MB; Martinez, D, 2023) |
| "To compare the effects of chlortalidone plus amiloride and amlodipine on blood pressure (BP) variability in patients with hypertension and obstructive sleep apnea syndrome (OSA)." | 5.69 | Effects of chlorthalidone plus amiloride compared with amlodipine on short-term blood pressure variability in individuals with hypertension and obstructive sleep apnea: a randomized controlled trial. ( Borges, RB; Cichelero, FT; Fuchs, FD; Fuchs, SC; Hirakata, VN; Jorge, JA; Lucca, MB; Martinez, D, 2023) |
| "Forty-four patients with hypertension and severe OSA (apnea/hypopnea index > 30) received stepped dose titration of antihypertensive treatment, consisting of valsartan 160 mg + amlodipine 5-10 mg + hydrochlorothiazide 25 mg." | 5.17 | Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension. ( Aksenova, AV; Chazova, IE; Elfimova, EM; Galitsin, PV; Litvin, AY; Rogoza, AN; Sukmarova, ZN, 2013) |
| "We compared the effects of atenolol (50 mg), amlodipine (5 mg), enalapril (20 mg), hydrochlorothiazide (25 mg), and losartan (50 mg) given in once-daily oral doses on office and ambulatory blood pressures (BPs) in patients with hypertension and obstructive sleep apnea (OSA)." | 5.09 | Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea. ( Grote, L; Hedner, J; Kraiczi, H; Peker, Y, 2000) |
| " We investigated the relevant impact of different dosing times of antihypertensive drugs beyond CPAP application." | 2.80 | Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study. ( Andrikou, I; Aragiannis, D; Bilo, G; Dimitriadis, K; Filis, K; Kasiakogias, A; Parati, G; Sideris, S; Stefanadis, C; Thomopoulos, C; Tsiachris, D; Tsioufis, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lucca, MB | 1 |
| Jorge, JA | 1 |
| Cichelero, FT | 1 |
| Martinez, D | 1 |
| Borges, RB | 1 |
| Hirakata, VN | 1 |
| Fuchs, FD | 1 |
| Fuchs, SC | 1 |
| Shi, J | 1 |
| Yuan, Y | 1 |
| Deng, X | 1 |
| Pan, Y | 1 |
| He, M | 1 |
| Liu, G | 1 |
| Sun, D | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Li, Y | 1 |
| Litvin, AY | 1 |
| Sukmarova, ZN | 1 |
| Elfimova, EM | 1 |
| Aksenova, AV | 1 |
| Galitsin, PV | 1 |
| Rogoza, AN | 2 |
| Chazova, IE | 1 |
| Kasiakogias, A | 1 |
| Tsioufis, C | 1 |
| Thomopoulos, C | 1 |
| Andrikou, I | 1 |
| Aragiannis, D | 1 |
| Dimitriadis, K | 1 |
| Tsiachris, D | 1 |
| Bilo, G | 1 |
| Sideris, S | 1 |
| Filis, K | 1 |
| Parati, G | 1 |
| Stefanadis, C | 1 |
| Zidek, W | 1 |
| Zelveian, PA | 1 |
| Oshchepkova, EV | 1 |
| Buniatian, MS | 1 |
| Kraiczi, H | 1 |
| Hedner, J | 1 |
| Peker, Y | 1 |
| Grote, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Independent Role of Continuous Positive Airway Pressure Therapy on Systemic Arterial Pressure in Patients With Sleep Apnea Syndrome and Arterial Hypertension[NCT00801671] | Phase 3 | 50 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Comparative Study of Effect of Valsartan 160mg Treatment Versus Continuous Positive Airway Pressure on Arterial Blood Pressure in Patients Who Have an Obstructive Sleep Apnea Syndrome and a Weak or Moderate Hypertension.[NCT00409487] | Phase 4 | 60 participants (Anticipated) | Interventional | 2006-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for amlodipine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Effects of chlorthalidone plus amiloride compared with amlodipine on short-term blood pressure variability in individuals with hypertension and obstructive sleep apnea: a randomized controlled trial.
Topics: Adult; Amiloride; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Am | 2023 |
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2019 |
Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Blo | 2013 |
Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C | 2015 |
Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anti | 2000 |
2 other studies available for amlodipine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
[Sleep apnea: RR lowering drugs need to be administered in the evening].
Topics: Amlodipine; Blood Pressure; Cross-Over Studies; Drug Chronotherapy; Drug Therapy, Combination; Human | 2015 |
[Characteristics of hypotensive effect in patients with arterial hypertension and desaturation signs of obstructive sleep apnea syndrome during sleep].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Gas Monitoring, Transcutaneous; Blood Pressu | 2004 |