Page last updated: 2024-10-22

amlodipine and Shock

amlodipine has been researched along with Shock in 8 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
" Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock."8.12Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022)
" In both experimental models and clinical cases of vasodilatory shock, methylene blue improves hemodynamic measures."7.81Efficacy of methylene blue in an experimental model of calcium channel blocker-induced shock. ( Bania, TC; Chu, J; Donovan, S; Hoffman, RS; Jang, DH; Nelson, LS, 2015)
"This is a single case report where a poisoned patient developed vasodilatory shock following ingestion of atenolol, amlodipine, and valsartan."7.81Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report. ( Cole, JB; Laes, JR; Williams, DM, 2015)
"Amlodipine is a potent vasodilator with a long half-life and delayed onset of action that is particularly concerning after an overdose."5.37Methylene blue in the treatment of refractory shock from an amlodipine overdose. ( Hoffman, RS; Jang, DH; Nelson, LS, 2011)
" Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock."4.12Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022)
" In both experimental models and clinical cases of vasodilatory shock, methylene blue improves hemodynamic measures."3.81Efficacy of methylene blue in an experimental model of calcium channel blocker-induced shock. ( Bania, TC; Chu, J; Donovan, S; Hoffman, RS; Jang, DH; Nelson, LS, 2015)
"We describe the case of a 58-year-old woman who developed a severe distributive shock following the intentional ingestion of a large overdose of amlodipine (480 mg) combined with valsartan (3680 mg)."3.81Mixed amlodipine/valsartan overdose treated by the molecular adsorbent recirculating system (MARS™). ( Capron, A; Galloy, AC; Gérard, L; Hantson, P, 2015)
"This is a single case report where a poisoned patient developed vasodilatory shock following ingestion of atenolol, amlodipine, and valsartan."3.81Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report. ( Cole, JB; Laes, JR; Williams, DM, 2015)
" We describe a rare case of massive overdose of lercanidipine with shock, refractory to conventional therapies and multi-organ failure."3.80Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose. ( Javeri, Y; Juneja, D; Nasa, P; Singh, A; Singh, O, 2014)
"Amlodipine is a potent vasodilator with a long half-life and delayed onset of action that is particularly concerning after an overdose."1.37Methylene blue in the treatment of refractory shock from an amlodipine overdose. ( Hoffman, RS; Jang, DH; Nelson, LS, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Koliastasis, L1
Lampadakis, I1
Milkas, A1
Strempelas, P1
Sourides, V1
Kakava, K1
Tsioufis, P1
Papaioannou, S1
Raj, A1
Panda, PK1
Singh, SS1
Nasa, P1
Singh, A1
Juneja, D1
Singh, O1
Javeri, Y1
Jang, DH2
Donovan, S1
Nelson, LS2
Bania, TC1
Hoffman, RS2
Chu, J1
Gérard, L1
Galloy, AC1
Capron, A1
Hantson, P1
Laes, JR1
Williams, DM1
Cole, JB1
Varpula, T1
Rapola, J1
Sallisalmi, M1
Kurola, J1

Other Studies

8 other studies available for amlodipine and Shock

ArticleYear
Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia.
    Cardiovascular toxicology, 2022, Volume: 22, Issue:1

    Topics: Aged; Amlodipine; Calcium Channel Blockers; COVID-19; Drug Overdose; Female; Humans; Hyperinsulinism

2022
Amlodipine (150 mg) Poisoning: A Case Study.
    Current drug safety, 2018, Volume: 13, Issue:2

    Topics: Adolescent; Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Hypotension; Shock;

2018
Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2014, Volume: 25, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Charcoal; Dihydropyridines; Dru

2014
Efficacy of methylene blue in an experimental model of calcium channel blocker-induced shock.
    Annals of emergency medicine, 2015, Volume: 65, Issue:4

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Disease Models, Animal; Free Radical Scavengers; Guan

2015
Mixed amlodipine/valsartan overdose treated by the molecular adsorbent recirculating system (MARS™).
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6

    Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihyp

2015
Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:4

    Topics: Amlodipine; Atenolol; Hemodynamics; Humans; Male; Methylene Blue; Middle Aged; Shock; Valsartan; Vas

2015
Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:3

    Topics: Acidosis, Lactic; Amlodipine; Calcium Channel Blockers; Cardiotonic Agents; Coma; Drug Overdose; Ech

2009
Methylene blue in the treatment of refractory shock from an amlodipine overdose.
    Annals of emergency medicine, 2011, Volume: 58, Issue:6

    Topics: Adult; Amlodipine; Cyclic GMP; Female; Humans; Methylene Blue; Shock; Vasodilator Agents

2011