Page last updated: 2024-10-22

amlodipine and Renal Artery Stenosis

amlodipine has been researched along with Renal Artery Stenosis in 8 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Research Excerpts

ExcerptRelevanceReference
"Renal artery stenosis is among the most common curable causes of hypertension."2.70Resistance to antihypertensive medication as predictor of renal artery stenosis: comparison of two drug regimens. ( Deinum, J; Derkx, FH; Krijnen, P; Postma, CT; Schalekamp, MA; van Jaarsveld, BC; Woittiez, AJ, 2001)
"Aggressive treatment of hypertension resulted in complete resolution of the clinical and radiologic features of the syndrome."1.43Does this patient have hypertensive encephalopathy? ( Argyropoulou, MI; Christopoulou, F; Elisaf, M; Kosta, P; Rizos, EC, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Jafari, R1
Rostami, Z1
Nikpoor, M1
Javanbakht, M1
Ghahroudi, MS1
Hosseini, MS1
Einollahi, B1
Pathak, AS1
Rojas, M1
Stouffer, GA1
Cooper, CJ1
Murphy, TP1
Cutlip, DE1
Jamerson, K1
Henrich, W1
Reid, DM1
Cohen, DJ1
Matsumoto, AH1
Steffes, M1
Jaff, MR1
Prince, MR1
Lewis, EF1
Tuttle, KR1
Shapiro, JI1
Rundback, JH1
Massaro, JM1
D'Agostino, RB1
Dworkin, LD1
Christopoulou, F1
Rizos, EC1
Kosta, P1
Argyropoulou, MI1
Elisaf, M1
Campbell, P1
Singh, KP1
Schuchard, G1
Jain, K1
White, WB1
van Jaarsveld, BC2
Derkx, FH2
Krijnen, P3
Pieterman, H1
Man in't Veld, AJ1
Woittiez, AJ2
Dees, A2
Postma, CT2
Schalekamp, MA2
van Jaarsveld, B1
Bartelink, A1
Derkx, F1
Man in't Veld, A1
Schalekamp, M1
Deinum, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL)[NCT00081731]Phase 3947 participants (Actual)Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

30% Reduction of eGFR From Baseline, Persisting for Greater Than or Equal to 60 Days

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy77
Stenting68

Cardiovascular or Renal Death

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy20
Stenting20

Composite Endpoint: Death From Cardiovascular or Renal Causes, Stroke, Myocardial Infarction, Hospitalization for CHF, Progressive Renal Insufficiency, or Permanent Renal Replacement Therapy

Only the first event per participant is included in the composite (NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy169
Stenting161

Hospitalization for Congestive Heart Failure

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy26
Stenting27

Myocardial Infarction

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy27
Stenting30

Need for Renal Replacement Therapy

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy3
Stenting4

Stroke

(NCT00081731)
Timeframe: Measured at every 3 months for the first year and annually thereafter

Interventionparticipants (Number)
Optimal Medical Therapy16
Stenting12

Trials

4 trials available for amlodipine and Renal Artery Stenosis

ArticleYear
Stenting and medical therapy for atherosclerotic renal-artery stenosis.
    The New England journal of medicine, 2014, Jan-02, Volume: 370, Issue:1

    Topics: Aged; Amlodipine; Angioplasty, Balloon; Angiotensin II Type 1 Receptor Blockers; Anticholesteremic A

2014
'Hypertension resistant to two-drug treatment' is a useful criterion to select patients for angiography: the 'Dutch Renal Artery Stenosis Intervention Cooperative' (DRASTIC) study.
    Contributions to nephrology, 1996, Volume: 119

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiography; Antihypertensive Agents; Atenolol; Drug Resistance

1996
The Dutch Renal Artery Stenosis Intervention Cooperative (DRASTIC) Study: rationale, design and inclusion data.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1998, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiography; Angioplasty, Balloon; Angiotensin-Converting Enzym

1998
Resistance to antihypertensive medication as predictor of renal artery stenosis: comparison of two drug regimens.
    Journal of human hypertension, 2001, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cohort Studi

2001

Other Studies

4 other studies available for amlodipine and Renal Artery Stenosis

ArticleYear
Detection of significant left renal artery stenosis caused by fibromuscular dysplasia with selective angiography.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2020, Jan-14, Volume: 91, Issue:4

    Topics: Amlodipine; Angioplasty, Balloon; Antihypertensive Agents; Computed Tomography Angiography; Drug Com

2020
Expression of Cyr61 in ApoE
    Scientific reports, 2021, 02-11, Volume: 11, Issue:1

    Topics: Amides; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Blood Press

2021
Does this patient have hypertensive encephalopathy?
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Brain; Carbazoles; Carvedilol; Computed Tom

2016
Severe circadian hypertension in a young man.
    The American journal of medicine, 2011, Volume: 124, Issue:10

    Topics: Amlodipine; Angioplasty, Balloon; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Ci

2011