Page last updated: 2024-10-22

amlodipine and Osteoarthritis

amlodipine has been researched along with Osteoarthritis in 7 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"The US Food and Drug Administration recently granted an approved indication for the first fixed-dose combination antihypertensive (amlodipine) and nonsteroidal anti-inflammatory drug (celecoxib) for treatment of comorbid hypertension and osteoarthritis."9.01Fixed-Dose Combination Amlodipine/Celecoxib (Consensi) for Hypertension and Osteoarthritis. ( Cooper-DeHoff, RM; Smith, SM, 2019)
"Patients with osteoarthritis are often affected by a number of cardiovascular comorbidities, including hypertension, which is present in about 40% of cases."6.58Amlodipine and celecoxib for treatment of hypertension and osteoarthritis pain. ( Angeli, F; Reboldi, G; Signorotti, S; Trapasso, M; Verdecchia, P, 2018)
"The US Food and Drug Administration recently granted an approved indication for the first fixed-dose combination antihypertensive (amlodipine) and nonsteroidal anti-inflammatory drug (celecoxib) for treatment of comorbid hypertension and osteoarthritis."5.01Fixed-Dose Combination Amlodipine/Celecoxib (Consensi) for Hypertension and Osteoarthritis. ( Cooper-DeHoff, RM; Smith, SM, 2019)
"Patients with osteoarthritis are often affected by a number of cardiovascular comorbidities, including hypertension, which is present in about 40% of cases."2.58Amlodipine and celecoxib for treatment of hypertension and osteoarthritis pain. ( Angeli, F; Reboldi, G; Signorotti, S; Trapasso, M; Verdecchia, P, 2018)
"Drug induced linear IgA bullous dermatosis (LABD) is a rare blistering disease that has been shown to be associated with the use of various medications."1.48Diffuse vesiculobullous eruption with systemic findings. ( Falkner, RC; Helmandollar, KJ; Hoverson, KR; Meyerle, JH, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Piszczatoski, CR1
Smith, SM2
Helmandollar, KJ1
Hoverson, KR1
Falkner, RC1
Meyerle, JH1
Cooper-DeHoff, RM1
Angeli, F1
Trapasso, M1
Signorotti, S1
Verdecchia, P1
Reboldi, G1
Shukla, AK1
Jhaj, R1
Pavlicević, I1
Kuzmanić, M1
Rumboldt, M1
Rumboldt, Z1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Relevance of the Interaction Between Antihypertensive and Antirheumatic Drugs in a Family Practice[NCT00631514]Phase 488 participants (Actual)Interventional2005-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amlodipine and Osteoarthritis

ArticleYear
Fixed-Dose Combination Amlodipine/Celecoxib (Consensi) for Hypertension and Osteoarthritis.
    The American journal of medicine, 2019, Volume: 132, Issue:2

    Topics: Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Celecoxib; Humans; Hyp

2019
Amlodipine and celecoxib for treatment of hypertension and osteoarthritis pain.
    Expert review of clinical pharmacology, 2018, Volume: 11, Issue:11

    Topics: Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Celecoxib; Drug Combin

2018

Trials

1 trial available for amlodipine and Osteoarthritis

ArticleYear
Interaction between antihypertensives and NSAIDs in primary care: a controlled trial.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2008,Fall, Volume: 15, Issue:3

    Topics: Acetaminophen; Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; B

2008

Other Studies

4 other studies available for amlodipine and Osteoarthritis

ArticleYear
Consensi --a fixed dose combination of amlodipine and celecoxib.
    The Medical letter on drugs and therapeutics, 2020, Mar-09, Volume: 62, Issue:1593

    Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Celecoxib; Cyclooxygenase 2 Inhibitor

2020
Fixed-dose combination amlodipine-celecoxib for treatment of hypertension and osteoarthritis pain: an up-to-date evaluation.
    Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Celecoxib; Drug Combinations; Humans; Hypertens

2021
Diffuse vesiculobullous eruption with systemic findings.
    Dermatology online journal, 2018, May-15, Volume: 24, Issue:5

    Topics: Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arthralgia; Drug Hyper

2018
Consensi: Is it a conscientious combination?
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Arthralgia; Blood Pressure; Celecoxib; Clinical Trials as Topic

2019