amlodipine has been researched along with Myocardial Ischemia in 60 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amlodipine did not increase cardiovascular morbidity or mortality in patients with severe heart failure." | 9.08 | Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group. ( Belkin, RN; Carson, PE; Cropp, AB; DeMets, DL; Frid, D; Ghali, JK; Miller, AB; Neuberg, GW; O'Connor, CM; Packer, M; Pressler, ML; Wertheimer, JH, 1996) |
| "This study was carried out to determine the effect of the once-daily calcium channel blocking agent amlodipine (half-life 35 to 50 h) on the circadian pattern of myocardial ischemia in patients with chronic stable angina." | 9.07 | Amlodipine reduces transient myocardial ischemia in patients with coronary artery disease: double-blind Circadian Anti-Ischemia Program in Europe (CAPE Trial). ( Deanfield, JE; Detry, JM; Lichtlen, PR; Magnani, B; Sellier, P; Thaulow, E, 1994) |
| "The efficacy and safety of amlodipine (5-10 mg once daily) and diltiazem (30-60 mg three times daily) were compared in 40 patients with symptomatic myocardial ischemia." | 9.07 | Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia. ( Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V, 1991) |
| "The efficacy and safety of amlodipine (5-10 mg) once daily were studied in an open study in patients with symptomatic myocardial ischemia." | 9.07 | An open multicenter efficacy and safety evaluation of amlodipine in the treatment of symptomatic myocardial ischemia. ( Beckerman, B, 1991) |
| "To evaluate the efficacy and safety of a fixed-term combination of β-blocker bisoprolol and the calcium antagonist amlodipine in the outpatient treatment of patients with arterial hypertension (AH) and coronary heart disease (CHD)." | 7.80 | [Evaluating the effectiveness of a fixed combination of amlodipine and bisoprolol in ambulatory patients with arterial hypertension and ischemic heart disease]. ( Chesnikova, AI; Kolomatskaia, OE; Safronenko, VA, 2014) |
| " In comparison with other antianginal drugs, once-daily amlodipine at a dosage range of 5-10 mg demonstrated antianginal activity comparable to thrice-daily diltiazem and once-daily nadolol." | 7.77 | Usefulness of amlodipine for angina pectoris. ( Taylor, SH, 1994) |
| "To assess effect of calcium antagonists amlodipine and verapamil on the risk of development of atrial fibrillation after coronary artery bypass surgery." | 7.72 | [Effect of calcium antagonists verapamil and amlodipine on the risk of development of atrial fibrillation after coronary artery bypass grafting]. ( Afanas'ev, SA; Akhmedov, ShD; Antonchenko, IV; Dzhavadova, GK; Evtushenko, AV; Kandinskiĭ, ML; Kozlov, BN; Popov, SV; Shipulin, VM; Vecherskiĭ, IuIu, 2003) |
| "Possibilities of secondary prevention of reperfusion syndrome with amlodipine was assessed in 46 patients (39 with class III-IV angina after myocardial infarction and 7 with non ST elevation acute coronary syndrome)." | 7.72 | [Reperfusion syndrome after direct myocardial revascularization on beating heart in patients with ischemic heart disease. Possibilities of prevention with amlodipine]. ( Akhmedov, ShD; Dzhavadova, GK; Kandinskiĭ, ML; Tepliakov, AT; Vesnina, ZhV, 2003) |
| " The most frequent adverse events were visual symptoms and sinus bradycardia with ivabradine (0." | 6.73 | Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial. ( Ford, I; Fox, KM; Ruzyllo, W; Tendera, M, 2007) |
| "Amlodipine was preferred to another calcium antagonist for this study because it is among the least negatively inotropic of these drugs." | 5.29 | Possible prevention by amlodipine of ventricular fibrillation related to brief ischemia episodes. ( Aupetit, JF; Faucon, G; Frassati, D; Freysz, M; Timour, Q, 1996) |
| "Amlodipine was the preferred calcium antagonist for this study because it is only moderately negatively inotropic." | 5.29 | Delay by a calcium antagonist, amlodipine, of the onset of primary ventricular fibrillation in myocardial ischemia. ( Aupetit, JF; Bui-Xuan, B; Faucon, G; Timour, Q, 1996) |
| "The hypotensive and antiischemic activity of combined therapy with dihydropyridine group (amlodipine) and non-dihydropyridine group (verapamil retard) calcium antagonists (CA) as well as tolerance to this therapy were studied in 43 patients suffering from coronary heart disease (CAD) with II-III functional class exertional angina and II degree essential hypertension during 24 weeks." | 5.12 | [Evaluation of hypotensive and antiischemic effects of a combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients suffering from coronary artery disease with arterial hypertension]. ( Abramova, GN; Berenshteĭn, NV; Burmistrova, LF; Iskendeerov, BG; Lokhina, TV; Shibaeva, TM, 2006) |
| "To determine whether, at trough levels, ranolazine improves the total exercise time of patients who have symptoms of chronic angina and who experience angina and ischemia at low workloads despite taking standard doses of atenolol, amlodipine, or diltiazem and to determine times to angina onset and to electrocardiographic evidence of myocardial ischemia, effect on angina attacks and nitroglycerin use, and effect on long-term survival in an open-label observational study extension." | 5.11 | Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. ( Chaitman, BR; Chumakova, G; Kuch, J; Parker, JO; Pepine, CJ; Skettino, SL; Skopal, J; Wang, W; Wolff, AA, 2004) |
| "The Circadian Anti-ischemia Program in Europe (CAPE II) compared the efficacy of amlodipine and diltiazem (Adizem XL) and the combination of amlodipine/atenolol and diltiazem (Adizem XL)/isosorbide 5-mononitrate on exercise and ambulatory myocardial ischemia during regular therapy and after omission of medication." | 5.10 | Medical treatment of myocardial ischemia in coronary artery disease: effect of drug regime and irregular dosing in the CAPE II trial. ( Beckerman, B; Brennan, C; Bultas, J; Deanfield, JE; Detry, JM; Lichtlen, PR; Sellier, P; Thaulow, E; Young, ST, 2002) |
| "Amlodipine did not increase cardiovascular morbidity or mortality in patients with severe heart failure." | 5.08 | Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group. ( Belkin, RN; Carson, PE; Cropp, AB; DeMets, DL; Frid, D; Ghali, JK; Miller, AB; Neuberg, GW; O'Connor, CM; Packer, M; Pressler, ML; Wertheimer, JH, 1996) |
| "Three hundred nine patients with coronary artery disease, stable angina pectoris, and positive exercise tests were randomized to receive mibefradil (50, 100, or 150 mg), amlodipine (10 mg), or placebo." | 5.08 | Efficacy of mibefradil compared with amlodipine in suppressing exercise-induced and daily silent ischemia: results of a multicenter, placebo-controlled trial. ( Braat, S; Kadr, H; Kobrin, I; Ramires, JA; Rutsch, W; Tzivoni, D, 1997) |
| "This study was carried out to determine the effect of the once-daily calcium channel blocking agent amlodipine (half-life 35 to 50 h) on the circadian pattern of myocardial ischemia in patients with chronic stable angina." | 5.07 | Amlodipine reduces transient myocardial ischemia in patients with coronary artery disease: double-blind Circadian Anti-Ischemia Program in Europe (CAPE Trial). ( Deanfield, JE; Detry, JM; Lichtlen, PR; Magnani, B; Sellier, P; Thaulow, E, 1994) |
| "The efficacy and safety of amlodipine (5-10 mg once daily) and diltiazem (30-60 mg three times daily) were compared in 40 patients with symptomatic myocardial ischemia." | 5.07 | Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia. ( Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V, 1991) |
| "The efficacy and safety of amlodipine (5-10 mg) once daily were studied in an open study in patients with symptomatic myocardial ischemia." | 5.07 | An open multicenter efficacy and safety evaluation of amlodipine in the treatment of symptomatic myocardial ischemia. ( Beckerman, B, 1991) |
| "In a group of 32 patients with combined ischemic heart disease (IHD) and arterial hypertension (AH) we studied dynamics of parameters of blood pressure and ECG 24-hour monitoring, as well as ultrasound structural and functional parameters of left and right ventricles during 3-month therapy with fixed dose combination of perindopril arginine (10." | 3.91 | ( Drobotya, NV; Guseynova, ES; Morgunov, MN; Torosyan, SS, 2019) |
| "To evaluate the efficacy and safety of a fixed-term combination of β-blocker bisoprolol and the calcium antagonist amlodipine in the outpatient treatment of patients with arterial hypertension (AH) and coronary heart disease (CHD)." | 3.80 | [Evaluating the effectiveness of a fixed combination of amlodipine and bisoprolol in ambulatory patients with arterial hypertension and ischemic heart disease]. ( Chesnikova, AI; Kolomatskaia, OE; Safronenko, VA, 2014) |
| "Mibefradil was found to be well tolerated and safe; this held true for patients on chronic anti-anginal background therapy." | 3.79 | Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist. ( Bieska, G; Charlon, V; Kobrin, I; Lindberg, E; Pordy, R, 1998) |
| " In comparison with other antianginal drugs, once-daily amlodipine at a dosage range of 5-10 mg demonstrated antianginal activity comparable to thrice-daily diltiazem and once-daily nadolol." | 3.77 | Usefulness of amlodipine for angina pectoris. ( Taylor, SH, 1994) |
| "Verapamil and amlodipine produced a potent antiischemic effect and reduced the area of myocardial infarction in rats." | 3.72 | Oxygen-dependent mechanisms underlying the antiischemic effect of verapamil and amlodipine. ( Gatsura, SV, 2004) |
| "Possibilities of secondary prevention of reperfusion syndrome with amlodipine was assessed in 46 patients (39 with class III-IV angina after myocardial infarction and 7 with non ST elevation acute coronary syndrome)." | 3.72 | [Reperfusion syndrome after direct myocardial revascularization on beating heart in patients with ischemic heart disease. Possibilities of prevention with amlodipine]. ( Akhmedov, ShD; Dzhavadova, GK; Kandinskiĭ, ML; Tepliakov, AT; Vesnina, ZhV, 2003) |
| "To assess effect of calcium antagonists amlodipine and verapamil on the risk of development of atrial fibrillation after coronary artery bypass surgery." | 3.72 | [Effect of calcium antagonists verapamil and amlodipine on the risk of development of atrial fibrillation after coronary artery bypass grafting]. ( Afanas'ev, SA; Akhmedov, ShD; Antonchenko, IV; Dzhavadova, GK; Evtushenko, AV; Kandinskiĭ, ML; Kozlov, BN; Popov, SV; Shipulin, VM; Vecherskiĭ, IuIu, 2003) |
| "Atorvastatin was as potent an anti-ischaemic agent as amlodipine." | 2.75 | Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering? ( Beckerman, B; Buch, J; Bultas, J; Deanfield, JE; Sellier, P; Shi, H; Thaulow, E; Yunis, C, 2010) |
| "The occurrence of sudden cardiac death (SCD) in patients with silent ischemia after myocardial infarction (MI) and the factors facilitating SCD are unknown." | 2.74 | Sudden cardiac death in patients with silent myocardial ischemia after myocardial infarction (from the Swiss Interventional Study on Silent Ischemia Type II [SWISSI II]). ( Abbate, A; Erne, P; Jamshidi, P; Kobza, R; Pfisterer, M; Schoenenberger, AW; Stuck, AE; Zuber, M, 2009) |
| " The most frequent adverse events were visual symptoms and sinus bradycardia with ivabradine (0." | 2.73 | Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial. ( Ford, I; Fox, KM; Ruzyllo, W; Tendera, M, 2007) |
| "3% of amlodipine patients recording adverse events, compared with 13." | 2.67 | Amlodipine and the total ischemic burden: circadian anti-ischemia program in Europe (CAPE) trial-methodology, safety and toleration. The Steering Committee members and all of the investigators. ( Detry, JM, 1994) |
| "Treatment with diltiazem resulted in a significant lengthening of sinus cycle length (SCL, p < 0." | 2.67 | Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy. ( Biscione, F; Lanza, GA; Manzoli, A; Natale, A; Santarelli, P, 1994) |
| "Amlodipine has also been found to provide improved antianginal effects when combined to treatment with beta blockers and/or long-acting nitrates." | 2.67 | Amlodipine once a day in stable angina: double-blind crossover comparison with placebo. ( Cheitlin, MD; Das, SK; Deedwania, PC; Pasternak, RC; Pool, PE; Singh, JB, 1993) |
| "Rats treated with amlodipine showed improved postischemia neovascularization and cardiac function, together with reduced cardiac remodeling, decreased interstitial fibrosis, and cardiomyocyte apoptosis." | 1.43 | Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization. ( Dong, L; Ferro, A; Kang, L; Sun, J; Xie, J; Xu, B, 2016) |
| "Cardiac complications were defined as left ventricular hypertrophy (LVH) and ischemic heart disease (IHD)." | 1.35 | Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial. ( Fujimoto, A; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Ueshima, K; Yasuno, S, 2009) |
| "Hypertension is a complex disease, the treatment of which should not only lower systolic and diastolic blood pressure but also attenuate the secondary consequences of the disease." | 1.29 | End-organ involvement and calcium antagonist therapy: animal studies. ( Nayler, WG, 1994) |
| "Amlodipine was the preferred calcium antagonist for this study because it is only moderately negatively inotropic." | 1.29 | Delay by a calcium antagonist, amlodipine, of the onset of primary ventricular fibrillation in myocardial ischemia. ( Aupetit, JF; Bui-Xuan, B; Faucon, G; Timour, Q, 1996) |
| "Amlodipine was preferred to another calcium antagonist for this study because it is among the least negatively inotropic of these drugs." | 1.29 | Possible prevention by amlodipine of ventricular fibrillation related to brief ischemia episodes. ( Aupetit, JF; Faucon, G; Frassati, D; Freysz, M; Timour, Q, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 31 (51.67) | 18.2507 |
| 2000's | 18 (30.00) | 29.6817 |
| 2010's | 11 (18.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drobotya, NV | 1 |
| Torosyan, SS | 1 |
| Guseynova, ES | 1 |
| Morgunov, MN | 1 |
| Mamou, Z | 1 |
| Chahine, M | 1 |
| Rhondali, O | 1 |
| Dehina, L | 1 |
| Chevalier, P | 1 |
| Descotes, J | 1 |
| Bui-Xuan, B | 2 |
| Romestaing, C | 1 |
| Timour, Q | 3 |
| Chesnikova, AI | 1 |
| Safronenko, VA | 1 |
| Kolomatskaia, OE | 1 |
| Sun, J | 1 |
| Xie, J | 1 |
| Kang, L | 1 |
| Ferro, A | 1 |
| Dong, L | 1 |
| Xu, B | 1 |
| Ueshima, K | 2 |
| Yasuno, S | 2 |
| Oba, K | 2 |
| Fujimoto, A | 2 |
| Ogihara, T | 2 |
| Saruta, T | 2 |
| Nakao, K | 2 |
| Schoenenberger, AW | 2 |
| Kobza, R | 1 |
| Jamshidi, P | 1 |
| Zuber, M | 2 |
| Abbate, A | 1 |
| Stuck, AE | 1 |
| Pfisterer, M | 2 |
| Erne, P | 2 |
| Deanfield, JE | 4 |
| Sellier, P | 3 |
| Thaulow, E | 3 |
| Bultas, J | 2 |
| Yunis, C | 1 |
| Shi, H | 1 |
| Buch, J | 1 |
| Beckerman, B | 3 |
| Kukushkin, SK | 1 |
| Manoshkina, EM | 1 |
| Nedogoda, SV | 1 |
| Tanaka, S | 1 |
| Li, AY | 1 |
| Ng, FH | 1 |
| Chan, FK | 1 |
| Tunggal, P | 1 |
| Chan, K | 1 |
| Lau, YK | 1 |
| Svistov, AS | 1 |
| Sukhov, VIu | 1 |
| Makiev, RG | 1 |
| Alanichev, AE | 1 |
| Kreutz, RP | 1 |
| Flockhart, DA | 1 |
| Detry, JM | 3 |
| Lichtlen, PR | 2 |
| Brennan, C | 1 |
| Young, ST | 1 |
| Popov, SV | 1 |
| Kandinskiĭ, ML | 2 |
| Kozlov, BN | 1 |
| Antonchenko, IV | 1 |
| Evtushenko, AV | 1 |
| Dzhavadova, GK | 2 |
| Vecherskiĭ, IuIu | 1 |
| Akhmedov, ShD | 2 |
| Afanas'ev, SA | 1 |
| Shipulin, VM | 1 |
| Tepliakov, AT | 1 |
| Vesnina, ZhV | 1 |
| Chaitman, BR | 1 |
| Pepine, CJ | 1 |
| Parker, JO | 1 |
| Skopal, J | 1 |
| Chumakova, G | 1 |
| Kuch, J | 1 |
| Wang, W | 1 |
| Skettino, SL | 1 |
| Wolff, AA | 1 |
| Gatsura, SV | 1 |
| Asanuma, H | 1 |
| Minamino, T | 1 |
| Sanada, S | 1 |
| Ogita, H | 1 |
| Kim, J | 1 |
| Fujita, M | 1 |
| Hirata, A | 1 |
| Tsukamoto, O | 1 |
| Ogai, A | 1 |
| Node, K | 1 |
| Hori, M | 1 |
| Tomoike, H | 1 |
| Kitakaze, M | 1 |
| Lucchesi, BR | 1 |
| Hoff, PT | 1 |
| Tamura, Y | 1 |
| Canale, C | 1 |
| Terrachini, V | 1 |
| Masperone, MA | 1 |
| Caponnetto, S | 1 |
| Karpov, IuA | 1 |
| Sasaki, T | 1 |
| Niwano, S | 1 |
| Kitano, Y | 1 |
| Izumi, T | 1 |
| Siragy, HM | 1 |
| Xue, C | 1 |
| Webb, RL | 1 |
| Brener, SJ | 1 |
| Ivanc, TB | 1 |
| Poliszczuk, R | 1 |
| Chen, M | 1 |
| Tuzcu, EM | 1 |
| Hu, T | 1 |
| Frid, DJ | 1 |
| Nissen, SE | 1 |
| Iskendeerov, BG | 1 |
| Burmistrova, LF | 1 |
| Berenshteĭn, NV | 1 |
| Abramova, GN | 1 |
| Lokhina, TV | 1 |
| Shibaeva, TM | 1 |
| Ruzyllo, W | 1 |
| Tendera, M | 1 |
| Ford, I | 1 |
| Fox, KM | 2 |
| Burckhardt, D | 1 |
| Kiowski, W | 1 |
| Dubach, P | 1 |
| Resink, T | 1 |
| Tabouy, L | 1 |
| Chauvet-Monges, AM | 1 |
| Salducci, MD | 1 |
| Crevat, A | 1 |
| Nayler, WG | 1 |
| Santarelli, P | 1 |
| Biscione, F | 1 |
| Natale, A | 1 |
| Manzoli, A | 1 |
| Lanza, GA | 1 |
| Davies, RF | 2 |
| Habibi, H | 2 |
| Klinke, WP | 2 |
| Dessain, P | 2 |
| Nadeau, C | 2 |
| Phaneuf, DC | 2 |
| Lepage, S | 2 |
| Raman, S | 1 |
| Herbert, M | 1 |
| Foris, K | 1 |
| Mehta, JL | 1 |
| Magnani, B | 1 |
| Perticone, F | 1 |
| Borelli, DA | 1 |
| Pugliese, F | 1 |
| Maio, R | 1 |
| Costa, R | 1 |
| Cosco, C | 1 |
| Ceravolo, R | 1 |
| Mattioli, PL | 1 |
| Mulcahy, D | 1 |
| Purcell, H | 1 |
| Sparrow, J | 1 |
| Cunningham, D | 1 |
| Wright, C | 1 |
| Taylor, SH | 1 |
| Vetrovec, GW | 1 |
| Deedwania, PC | 2 |
| Cheitlin, MD | 1 |
| Das, SK | 1 |
| Pool, PE | 1 |
| Singh, JB | 1 |
| Pasternak, RC | 1 |
| Linden, W | 1 |
| Buttars, JA | 1 |
| Sobey, CG | 1 |
| Dalipram, RA | 1 |
| Woodman, OL | 1 |
| Rumoroso, JR | 1 |
| Inguanzo, R | 1 |
| Cembellín, JC | 1 |
| Bodegas, A | 1 |
| Barrenetxea, JI | 1 |
| Roux, S | 1 |
| Bühler, M | 1 |
| Clozel, JP | 1 |
| Packer, M | 1 |
| O'Connor, CM | 1 |
| Ghali, JK | 1 |
| Pressler, ML | 1 |
| Carson, PE | 1 |
| Belkin, RN | 1 |
| Miller, AB | 1 |
| Neuberg, GW | 1 |
| Frid, D | 1 |
| Wertheimer, JH | 1 |
| Cropp, AB | 1 |
| DeMets, DL | 1 |
| Faucon, G | 2 |
| Aupetit, JF | 2 |
| Deanfield, J | 1 |
| Freysz, M | 1 |
| Frassati, D | 1 |
| Melcher, A | 1 |
| Dens, J | 1 |
| Curry, P | 1 |
| Hagel, H | 1 |
| Koenig, W | 1 |
| Höher, M | 1 |
| Tzivoni, D | 1 |
| Kadr, H | 1 |
| Braat, S | 1 |
| Rutsch, W | 1 |
| Ramires, JA | 1 |
| Kobrin, I | 2 |
| Bieska, G | 1 |
| Charlon, V | 1 |
| Lindberg, E | 1 |
| Pordy, R | 1 |
| van der Vring, JA | 1 |
| Daniëls, MC | 1 |
| Holwerda, NJ | 1 |
| Withagen, PJ | 1 |
| Schelling, A | 1 |
| Cleophas, TJ | 1 |
| Hendriks, MG | 1 |
| Becker, BF | 1 |
| Möbert, J | 1 |
| Glasser, SP | 1 |
| Frishman, W | 1 |
| White, WB | 1 |
| Stone, P | 1 |
| Johnson, MF | 1 |
| Zannad, F | 1 |
| Lazareva, ON | 1 |
| Mazur, NA | 1 |
| Pshenitsin, AI | 1 |
| Vikent'ev, VV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double Blind Atorvastatin Amlodipine Study (DUAAL) Effect Of Amlodipine, Atorvastatin And The Combination On Transient Myocardia Ischemia In Coronary Artery Disease.[NCT00159718] | Phase 4 | 360 participants | Interventional | 2001-07-31 | Completed | ||
| Effect of Amlodipine on Platelet Inhibition by Clopidogrel in Patients With Ischemic Heart Disease- a Prospective Randomized Controlled Trial[NCT01203696] | Phase 4 | 97 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| Regional and Systemic Hemodynamic Effects of a Long-term Administration of Amlodipine in Patients With Chronic Heart Failure Treated With a Combination of Enalapril, Furosemide and Digoxin[NCT00151619] | Phase 2 | 7 participants (Actual) | Interventional | 1999-02-10 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for amlodipine and Myocardial Ischemia
| Article | Year |
|---|---|
[Amlodipine in contemporary therapy of cardiovascular diseases].
Topics: Amlodipine; Biotransformation; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Hyper | 2010 |
[Ischemic heart disease combined with hypertension: peculiarities of course and selection of therapy].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2005 |
Usefulness of amlodipine for angina pectoris.
Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Dil | 1994 |
Treatment effects on the total ischaemic burden and prognostic implications.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as T | 1996 |
Nisoldipine CC: clinical experience in ischaemic heart disease.
Topics: Amlodipine; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; H | 1997 |
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Bloc | 1998 |
Circadian heart rate response to chronotherapy versus conventional therapy in patients with hypertension and myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Blood Pressure; C | 2000 |
26 trials available for amlodipine and Myocardial Ischemia
| Article | Year |
|---|---|
Sudden cardiac death in patients with silent myocardial ischemia after myocardial infarction (from the Swiss Interventional Study on Silent Ischemia Type II [SWISSI II]).
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angioplasty, Balloon, Coronary; Antihypertensi | 2009 |
Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering?
Topics: Aged, 80 and over; Amlodipine; Angina, Stable; Antihypertensive Agents; Atorvastatin; Chronic Diseas | 2010 |
Effect of amlodipine on platelet inhibition by clopidogrel in patients with ischaemic heart disease: a randomised, controlled trial.
Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Chi-Square Distribution; Clopidogrel; | 2013 |
Medical treatment of myocardial ischemia in coronary artery disease: effect of drug regime and irregular dosing in the CAPE II trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Calcium Channel B | 2002 |
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial.
Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Atenolol; Calcium Chan | 2004 |
Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Sc | 1991 |
An open multicenter efficacy and safety evaluation of amlodipine in the treatment of symptomatic myocardial ischemia.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Fem | 1991 |
[Evaluation of hypotensive and antiischemic effects of a combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients suffering from coronary artery disease with arterial hypertension].
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Drug Therap | 2006 |
Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial.
Topics: Aged; Amlodipine; Angina Pectoris; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardioton | 2007 |
Effects of anti-ischaemic drug therapy in silent myocardial ischaemia type I: the Swiss Interventional Study on Silent Ischaemia type I (SWISSI I): a randomized, controlled pilot study.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Bisoprolol; Death, Su | 2007 |
Amlodipine and the total ischemic burden: circadian anti-ischemia program in Europe (CAPE) trial-methodology, safety and toleration. The Steering Committee members and all of the investigators.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Data Interpretation, Statistical; Double-Blind Method | 1994 |
Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.
Topics: Adult; Aged; Amlodipine; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electroph | 1994 |
Effect of amlodipine, atenolol and their combination on myocardial ischemia during treadmill exercise and ambulatory monitoring. Canadian Amlodipine/Atenolol in Silent Ischemia Study (CASIS) Investigators.
Topics: Amlodipine; Atenolol; Cross-Over Studies; Drug Therapy, Combination; Electrocardiography, Ambulatory | 1995 |
Amlodipine reduces transient myocardial ischemia in patients with coronary artery disease: double-blind Circadian Anti-Ischemia Program in Europe (CAPE Trial).
Topics: Adult; Aged; Amlodipine; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug T | 1994 |
[An ergometric cross-over evaluation of the anti-ischemic efficacy of amlodipine and gallopamil in stable angina of effort].
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Angina Pectoris; Exercise Test; Female; Gallopamil; H | 1993 |
Usefulness of amlodipine for angina pectoris.
Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Dil | 1994 |
Amlodipine once a day in stable angina: double-blind crossover comparison with placebo.
Topics: Aged; Amlodipine; Angina Pectoris; Double-Blind Method; Electrocardiography; Exercise Test; Fatigue; | 1993 |
Relative importance of psychologic traits and severity of ischemia in causing angina during treadmill exercise. Canadian Amlodipine/Atenolol in Silent Ischemia Study (CASIS) Investigators.
Topics: Amlodipine; Angina Pectoris; Atenolol; Exercise Test; Exercise Tolerance; Female; Humans; Male; Midd | 1993 |
Treatment effects on the total ischaemic burden and variables with prognostic implications.
Topics: Amlodipine; Humans; Myocardial Ischemia; Prognosis; Vasodilator Agents | 1995 |
Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Cardiomyopathy, Dilated; Chronic Disease; Double-Blind M | 1996 |
Felodipine and amlodipine in stable angina pectoris: results of a randomized double-blind crossover trial.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blocker | 1997 |
Efficacy of mibefradil compared with amlodipine in suppressing exercise-induced and daily silent ischemia: results of a multicenter, placebo-controlled trial.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Double-Blind Method; Electrocardiography, | 1997 |
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Bloc | 1998 |
Anti-ischemic effects of amlodipine in patients with stable angina pectoris and myocardial ischemia during daily life. Amlodipine Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Double-Blind Method; Electr | 1999 |
Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Resear
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; B | 1999 |
[Effects of calcium antagonists on atherosclerosis progression and intima media thickness].
Topics: Amlodipine; Arteriosclerosis; Calcium Channel Blockers; Disease Progression; Echocardiography; Human | 2000 |
29 other studies available for amlodipine and Myocardial Ischemia
| Article | Year |
|---|---|
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Myocar | 2019 |
Effects of amlodipine and perindoprilate on the structure and function of mitochondria in ventricular cardiomyocytes during ischemia-reperfusion in the pig.
Topics: Action Potentials; Amlodipine; Animals; Calcium; Cell Death; Heart Rate; Heart Ventricles; Indoles; | 2015 |
[Evaluating the effectiveness of a fixed combination of amlodipine and bisoprolol in ambulatory patients with arterial hypertension and ischemic heart disease].
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Amlodipine; Bisoprolol; Blood Pressure; Calcium Channe | 2014 |
Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization.
Topics: Amlodipine; Animals; Cell Movement; Cytokines; Diabetic Angiopathies; Dose-Response Relationship, Dr | 2016 |
Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial.
Topics: Adrenergic Antagonists; Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calciu | 2009 |
[Combination of perindopril and amlodipine as optimal basis for realization of desirable clinical effects in the treatment of arterial hypertension with fixed drug combination].
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Card | 2011 |
Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) tria
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Coronar | 2011 |
[Use of SPECT-scanning of the heart in estimating of influence of drugs of the background therapy of ischemic heart disease on myocardial perfusion].
Topics: Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Cardiac-Gated Single-Photon Emission Compu | 2012 |
Amlodipine--not a significant contributor to clopidogrel non-response?
Topics: Amlodipine; Calcium Channel Blockers; Clopidogrel; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibi | 2013 |
[Effect of calcium antagonists verapamil and amlodipine on the risk of development of atrial fibrillation after coronary artery bypass grafting].
Topics: Adult; Aged; Amlodipine; Atrial Fibrillation; Calcium Channel Blockers; Coronary Artery Bypass; Huma | 2003 |
[Reperfusion syndrome after direct myocardial revascularization on beating heart in patients with ischemic heart disease. Possibilities of prevention with amlodipine].
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Echocardiography, Doppler; Elect | 2003 |
Oxygen-dependent mechanisms underlying the antiischemic effect of verapamil and amlodipine.
Topics: Amlodipine; Animals; Hemoglobins; Lipid Peroxidation; Malondialdehyde; Myocardial Infarction; Myocar | 2004 |
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.
Topics: Adenosine; Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Do | 2005 |
Cardioprotective effects of amlodipine in animal models of ischemia and reperfusion.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Cats; Coronary Ci | 1991 |
Two cases of Brugada syndrome associated with spontaneous clinical episodes of coronary vasospasm.
Topics: Acetylcholine; Amlodipine; Calcium Channel Blockers; Cardiovascular Agents; Coronary Vasospasm; Defi | 2006 |
Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia.
Topics: Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Calcium | 2006 |
Antihypertensive therapy and regression of coronary artery disease: insights from the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis (CAMELOT) and Norvasc for Regression of Manifest Atherosclerotic Lesions by Intravascular So
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block | 2006 |
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Bloc | 1994 |
End-organ involvement and calcium antagonist therapy: animal studies.
Topics: Administration, Oral; Amlodipine; Animals; Aorta, Thoracic; Arteriosclerosis; Binding Sites; Blood P | 1994 |
Emerging options in the management of myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Disease | 1994 |
Effects of amlodipine versus diltiazem on morning peak in myocardial ischemic activity in angina pectoris.
Topics: Aged; Amlodipine; Angina Pectoris; Circadian Rhythm; Diltiazem; Female; Humans; Male; Middle Aged; M | 1993 |
Hemodynamic and electrophysiologic effects of first- and second-generation calcium antagonists.
Topics: Amlodipine; Calcium Channel Blockers; Cardiac Output; Dihydropyridines; Electrophysiology; Female; H | 1994 |
Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.
Topics: Allopurinol; Amlodipine; Anesthetics; Animals; Dogs; Endothelium, Vascular; Female; Male; Myocardial | 1993 |
Left main coronary artery spasm.
Topics: Amlodipine; Angina Pectoris; Coronary Vasospasm; Diagnosis, Differential; Follow-Up Studies; Humans; | 1995 |
Mechanism of the antiischemic effect of mibefradil, a selective T calcium channel blocker in dogs: comparison with amlodipine.
Topics: Amlodipine; Angina Pectoris, Variant; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Block | 1996 |
Delay by a calcium antagonist, amlodipine, of the onset of primary ventricular fibrillation in myocardial ischemia.
Topics: Action Potentials; Amlodipine; Animals; Calcium Channel Blockers; Disease Models, Animal; Heart Cond | 1996 |
Possible prevention by amlodipine of ventricular fibrillation related to brief ischemia episodes.
Topics: Amlodipine; Animals; Electrophysiology; Female; Heart; Hemodynamics; Male; Myocardial Ischemia; Swin | 1996 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relati | 1999 |
[Comparative effects of amlodipine (stamlo) and enalapril (enam) on arterial pressure, painless myocardial ischemia and diastolic function of left ventricle in patients with arterial hypertension].
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 2000 |