Page last updated: 2024-10-22

amlodipine and Long QT Syndrome

amlodipine has been researched along with Long QT Syndrome in 2 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"A total of 170 outpatients aged 50-75 years with mild to moderate hypertension (SBP >130 and <180 mmHg and DBP >80 and <100 mmHg) and type 2 diabetes were randomly treated with aliskiren 300 mg or amlodipine 10 mg, both given once daily for 24 weeks, according to a prospective, open label, blinded-end point, parallel group design."5.16Effects of aliskiren on QT duration and dispersion in hypertensive patients with type 2 diabetes mellitus. ( Derosa, G; Fogari, R; Lazzari, P; Maffioli, P; Monti, C; Mugellini, A; Zoppi, A, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higa, A1
Hoshi, H1
Yanagisawa, Y1
Ito, E1
Morisawa, G1
Imai, JI1
Watanabe, S1
Takagi, M1
Fogari, R1
Zoppi, A1
Maffioli, P1
Monti, C1
Lazzari, P1
Mugellini, A1
Derosa, G1

Trials

1 trial available for amlodipine and Long QT Syndrome

ArticleYear
Effects of aliskiren on QT duration and dispersion in hypertensive patients with type 2 diabetes mellitus.
    Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:4

    Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabet

2012

Other Studies

1 other study available for amlodipine and Long QT Syndrome

ArticleYear
Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:6

    Topics: Amlodipine; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Cardiotoxicity; Ce

2017