Page last updated: 2024-10-22

amlodipine and Liver Cirrhosis

amlodipine has been researched along with Liver Cirrhosis in 2 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Amlodipine, a dihydropyridine calcium antagonist, was synthesized in an attempt to develop a compound with a pharmacokinetic profile characteristic of this class, which would also have an increased oral bioavailability and extended clearance time."2.38The pharmacokinetic profile of amlodipine. ( Abernethy, DR, 1989)
"Non-alcoholic steatohepatitis (NASH), which is a common liver disease in industrialized countries, is associated with obesity, hypertension, and type-2 diabetes (metabolic syndrome)."1.35ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. ( Cao, G; Mastai, R; Mella, J; Muñoz, MC; Pereyra, L; Toblli, JE, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toblli, JE1
Muñoz, MC1
Cao, G1
Mella, J1
Pereyra, L1
Mastai, R1
Abernethy, DR1

Reviews

1 review available for amlodipine and Liver Cirrhosis

ArticleYear
The pharmacokinetic profile of amlodipine.
    American heart journal, 1989, Volume: 118, Issue:5 Pt 2

    Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium

1989

Other Studies

1 other study available for amlodipine and Liver Cirrhosis

ArticleYear
ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:4

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme I

2008