amlodipine has been researched along with Kidney Failure in 18 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect and molecular mechanisms of amlodipine besylate combined with acupoint application of traditional Chinese medicine nursing on the treatment methods of renal failure and hypertension." | 9.30 | Effect of amlodipine besylate combined with acupoint application of traditional Chinese medicine nursing on the treatment of renal failure and hypertension by the PI3K/AKT pathway. ( Chi, R; Feng, L; Liang, W; Lv, S; Su, J; Zhu, Q, 2019) |
| "The present study was conducted to compare the renal and vascular protective effects of telmisartan and amlodipine in untreated hypertensive chronic kidney disease (CKD) patients with moderate renal insufficiency." | 9.13 | Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency. ( Inoue, T; Kawagoe, Y; Koide, H; Nakamura, T; Node, K; Suzuki, T; Ueda, Y, 2008) |
| "To determine whether amlodipine besylate decreases systemic arterial blood pressure (BP) and reduces the prevalence of complications in cats with induced hypertensive renal insufficiency." | 7.71 | Effects of the calcium channel antagonist amlodipine in cats with surgically induced hypertensive renal insufficiency. ( Brown, CA; Brown, SA; Cartier, LM; Elliot, J; Mathur, S; Moore, PA; Munday, JS; Newell, MA; Sheldon, SE; Syme, H, 2002) |
| "To study the effect and molecular mechanisms of amlodipine besylate combined with acupoint application of traditional Chinese medicine nursing on the treatment methods of renal failure and hypertension." | 5.30 | Effect of amlodipine besylate combined with acupoint application of traditional Chinese medicine nursing on the treatment of renal failure and hypertension by the PI3K/AKT pathway. ( Chi, R; Feng, L; Liang, W; Lv, S; Su, J; Zhu, Q, 2019) |
| "The present study was conducted to compare the renal and vascular protective effects of telmisartan and amlodipine in untreated hypertensive chronic kidney disease (CKD) patients with moderate renal insufficiency." | 5.13 | Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency. ( Inoue, T; Kawagoe, Y; Koide, H; Nakamura, T; Node, K; Suzuki, T; Ueda, Y, 2008) |
| "Associations between baseline proteinuria and proteinuria reduction by either irbesartan, amlodipine, or control for similar decrements in blood pressure and the cumulative incidence of renal end points were examined using the Kaplan-Meier method in patients enrolled in the Irbesartan Diabetic Nephropathy Trial." | 5.11 | Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy. ( Atkins, RC; Braden, G; Briganti, EM; Champion de Crespigny, PJ; DeFerrari, G; Drury, P; Hunsicker, LG; Lewis, EJ; Lewis, JB; Locatelli, F; Wiegmann, TB, 2005) |
| "An interim analysis of the AASK trial at three years demonstrates a renoprotective effect [slower decline in glomerular filtration rate (GFR), delayed onset of significant decrease in GFR, end-stage renal disease (ESRD) or death, and a decrease in urinary protein excretion] of the angiotensin converting enzyme (ACE) inhibitor, ramipril, as compared to the dihydropyridine calcium channel blocker (DHP-CCB), amlodipine, in patients with mild-to-moderate renal insufficiency." | 5.10 | ACE inhibition is effective and renoprotective in hypertensive nephrosclerosis: the African American Study of Kidney Disease and Hypertension (AASK) trial. ( Agodoa, L; Douglas, JG, 2003) |
| " Parallel-group, randomized, controlled trials that included at least 10 adults with baseline hypertension (SBP>or=140 mm Hg, DBP>or=90 mm Hg, or both), included at least 1 arm randomized to initial treatment with amlodipine monotherapy, had a minimum treatment duration of 8 weeks, and reported baseline and end-point blood pressure were included." | 4.82 | Effect of amlodipine on systolic blood pressure. ( Connelly, JE; Estok, RP; Fahrbach, KR; Frame, D; Levine, CB; Ludensky, V; Stone, LR, 2003) |
| "To determine whether amlodipine besylate decreases systemic arterial blood pressure (BP) and reduces the prevalence of complications in cats with induced hypertensive renal insufficiency." | 3.71 | Effects of the calcium channel antagonist amlodipine in cats with surgically induced hypertensive renal insufficiency. ( Brown, CA; Brown, SA; Cartier, LM; Elliot, J; Mathur, S; Moore, PA; Munday, JS; Newell, MA; Sheldon, SE; Syme, H, 2002) |
| "Reasonable sampling scheme is the important basis for establishing reliable population pharmacokinetic model." | 2.77 | [Modeling and simulation activities to design sampling scheme for population pharmacokinetic study on amlodipine]. ( Barrett, JS; Di, W; Guo, R; Huang, ZJ; Jing, NN; Ng, CM; Pei, Q; Yang, GP; Yuan, H; Zhang, BK; Zhou, YN; Zuo, XC, 2012) |
| "Amlodipine is a calcium antagonist of the dihydropyridine class." | 2.71 | Pharmacokinetics of amlodipine in hypertensive patients undergoing haemodialysis. ( Kungys, G; Naujoks, H; Wanner, C, 2003) |
| "A 35-year-old woman with a history of breast cancer, treated 3 years ago with surgery, radiation, and chemotherapy presented with a rapid onset of severe Raynaud's phenomenon." | 1.36 | Paraneoplastic Raynaud's phenomenon in a breast cancer survivor. ( Allen, D; Mittoo, S; Robinson, D, 2010) |
| "Renovascular hypertension was induced in the dogs by placing silver clips on both renal arteries to create 90% occlusion." | 1.32 | Effects of antihypertensive drugs on peritoneal vessels in hypertensive dogs with mild renal insufficiency. ( Imai, H; Ishida, Y; Nakamoto, H; Suzuki, H; Tomori, K, 2003) |
| "Structural features of amlodipine give the molecule physicochemical and pharmacokinetic properties that are unique among calcium antagonists." | 1.28 | Amlodipine: pharmacokinetic profile of a low-clearance calcium antagonist. ( Abernethy, DR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 13 (72.22) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, L | 1 |
| Su, J | 1 |
| Chi, R | 1 |
| Zhu, Q | 1 |
| Lv, S | 1 |
| Liang, W | 1 |
| Nakamura, T | 1 |
| Inoue, T | 1 |
| Suzuki, T | 1 |
| Kawagoe, Y | 1 |
| Ueda, Y | 1 |
| Koide, H | 1 |
| Node, K | 1 |
| Allen, D | 1 |
| Robinson, D | 1 |
| Mittoo, S | 1 |
| Khan, AH | 2 |
| Sattar, MA | 2 |
| Abdullah, NA | 2 |
| Johns, EJ | 2 |
| Zuo, XC | 1 |
| Yuan, H | 1 |
| Zhang, BK | 1 |
| Ng, CM | 1 |
| Barrett, JS | 1 |
| Yang, GP | 1 |
| Huang, ZJ | 1 |
| Pei, Q | 1 |
| Guo, R | 1 |
| Zhou, YN | 1 |
| Jing, NN | 1 |
| Di, W | 1 |
| Levine, CB | 1 |
| Fahrbach, KR | 1 |
| Frame, D | 1 |
| Connelly, JE | 1 |
| Estok, RP | 1 |
| Stone, LR | 1 |
| Ludensky, V | 1 |
| Kungys, G | 1 |
| Naujoks, H | 1 |
| Wanner, C | 1 |
| Douglas, JG | 1 |
| Agodoa, L | 1 |
| Ishida, Y | 1 |
| Tomori, K | 1 |
| Nakamoto, H | 1 |
| Imai, H | 1 |
| Suzuki, H | 1 |
| Mathur, S | 2 |
| Brown, CA | 2 |
| Dietrich, UM | 1 |
| Munday, JS | 2 |
| Newell, MA | 2 |
| Sheldon, SE | 2 |
| Cartier, LM | 2 |
| Brown, SA | 2 |
| Atkins, RC | 1 |
| Briganti, EM | 1 |
| Lewis, JB | 1 |
| Hunsicker, LG | 1 |
| Braden, G | 1 |
| Champion de Crespigny, PJ | 1 |
| DeFerrari, G | 1 |
| Drury, P | 1 |
| Locatelli, F | 1 |
| Wiegmann, TB | 1 |
| Lewis, EJ | 1 |
| Abernethy, DR | 1 |
| Ishikawa, K | 1 |
| Rakugi, H | 1 |
| Ogihara, T | 1 |
| Williams, B | 1 |
| Lacy, PS | 1 |
| Thom, SM | 1 |
| Cruickshank, K | 1 |
| Stanton, A | 1 |
| Collier, D | 1 |
| Hughes, AD | 1 |
| Thurston, H | 1 |
| O'Rourke, M | 1 |
| Janssen, JJ | 1 |
| Gans, RO | 1 |
| van der Meulen, J | 1 |
| Pijpers, R | 1 |
| ter Wee, PM | 1 |
| Syme, H | 1 |
| Elliot, J | 1 |
| Moore, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Outcomes in Atrial Fibrillation Patients Aided by Implantable Cardiac Monitor: Evaluation of Chronic Beta-blocker Use Versus As-needed Pharmacological Rate Control[NCT05745337] | Phase 1 | 20 participants (Anticipated) | Interventional | 2023-02-06 | Recruiting | ||
| A Randomized, Open-label Study Investigating the Effect of Bilateral Renal Artery Sympathetic Denervation by Catheter-based Radiofrequency Ablation on Blood Pressure and Disease Progression in Autosomal Dominant Polycystic Kidney Disease[NCT01932450] | Phase 2 | 100 participants (Anticipated) | Interventional | 2013-08-31 | Recruiting | ||
| Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)[NCT02584439] | Phase 3 | 30 participants (Anticipated) | Interventional | 2015-10-31 | Recruiting | ||
| Pulse Wave Velocity as a Predictor for Postoperative Cardiovascular Events[NCT03223441] | 543 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol[NCT02403349] | Phase 4 | 105 participants (Actual) | Interventional | 2012-05-31 | Active, not recruiting | ||
| Longitudinal Change of Arterial Stiffness Indices in Relation to Ambulatory Aortic and Branchial Pressure in Long Term Peritoneal Dialysis Patients[NCT03607747] | 40 participants (Anticipated) | Observational | 2018-07-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amlodipine and Kidney Failure
| Article | Year |
|---|---|
Effect of amlodipine on systolic blood pressure.
Topics: Age Factors; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Dose-Respo | 2003 |
[Recent multi-center clinical studies about calcium blockade and cardiovascular diseases].
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhi | 2006 |
8 trials available for amlodipine and Kidney Failure
8 other studies available for amlodipine and Kidney Failure
| Article | Year |
|---|---|
Paraneoplastic Raynaud's phenomenon in a breast cancer survivor.
Topics: Adult; Amlodipine; Antibodies, Antinuclear; Antineoplastic Agents; Breast Neoplasms; Edema; Female; | 2010 |
Effect of calcium channel blockade on adrenergically induced renal vasoconstriction in rat models of renal impairment.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Diabetic Nephropathies; Disease Models, Animal; Drug | 2009 |
Effects of antihypertensive drugs on peritoneal vessels in hypertensive dogs with mild renal insufficiency.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aquaporins; | 2003 |
Evaluation of a technique of inducing hypertensive renal insufficiency in cats.
Topics: Amlodipine; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Cat Disease | 2004 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking | 2005 |
Amlodipine: pharmacokinetic profile of a low-clearance calcium antagonist.
Topics: Adsorption; Adult; Aged; Aged, 80 and over; Aging; Amlodipine; Calcium Channel Blockers; Drug Intera | 1991 |
Influence of cisplatin-induced renal failure on the alpha(1)-adrenoceptor subtype causing vasoconstriction in the kidney of the rat.
Topics: Amlodipine; Animals; Cisplatin; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; I | 2007 |
Effects of the calcium channel antagonist amlodipine in cats with surgically induced hypertensive renal insufficiency.
Topics: Albuminuria; Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cat Diseases; Cats; Fema | 2002 |