Page last updated: 2024-10-22

amlodipine and Ischemia

amlodipine has been researched along with Ischemia in 7 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Amlodipine, a long acting calcium antagonist, was used to reduce the adverse effects of ischemic/reperfusion injury studied in isolated perfused rat livers."7.69Amlodipine improves hepatic hemodynamic and metabolic function in the isolated perfused rat liver after sequential cold and warm ischemia. ( Dunne, JB; Piratvisuth, T; Tredger, JM; Williams, R, 1995)
"Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics that seem to be attributable to a high degree of ionization."5.38Amlodipine-induced delirium in a patient with ischemic stroke. ( Dikici, S; Kocaman, G; Kocer, A; Ozdem, S, 2012)
" Intact FGF-23, the eGFR, proteinuria and the endothelium-dependent flow-mediated (FMD) response to ischemia and other parameters were measured at baseline and after 12-weeks of treatment with ramipril (n = 68) or amlodipine (n = 32)."5.19Ramipril lowers plasma FGF-23 in patients with diabetic nephropathy. ( Cetinkaya, H; Eyileten, T; Gok, M; Karaman, M; Kurt, YG; Mallamaci, F; Oguz, Y; Saglam, M; Sonmez, A; Unal, HU; Vural, A; Yilmaz, MI; Zoccali, C, 2014)
"Dexamethasone (DXM) can regulate the balance of neutrophil and cytokine and enhance the ischemia-reperfusion tolerance of the skin flap; amlodipine besylate (AB) can selectively expand the peripheral blood vessels and relieve the vascular smooth muscle spasm."3.76[Percutaneous penetration ability of dexamethasone-amlodipine besylate compound gel and its effect on survival of ischemic random skin flap]. ( Liu, K; Qin, Y; Wang, X; Zhang, J; Zhang, X; Zhong, L, 2010)
"Amlodipine, a long acting calcium antagonist, was used to reduce the adverse effects of ischemic/reperfusion injury studied in isolated perfused rat livers."3.69Amlodipine improves hepatic hemodynamic and metabolic function in the isolated perfused rat liver after sequential cold and warm ischemia. ( Dunne, JB; Piratvisuth, T; Tredger, JM; Williams, R, 1995)
"Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics that seem to be attributable to a high degree of ionization."1.38Amlodipine-induced delirium in a patient with ischemic stroke. ( Dikici, S; Kocaman, G; Kocer, A; Ozdem, S, 2012)
"Malignant hypertension is a well-defined condition associated with high blood pressure and acute target-organ damage."1.33Malignant hypertension with intestinal ischemia secondary to juxtaglomerular cell tumor. ( Leitão, AA; Leite, CA; Libório, AB; Marques, Fde O; Praxedes, JN; Testagrossa, L, 2005)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yilmaz, MI1
Sonmez, A1
Saglam, M1
Kurt, YG1
Unal, HU1
Karaman, M1
Gok, M1
Cetinkaya, H1
Eyileten, T1
Oguz, Y1
Vural, A1
Mallamaci, F1
Zoccali, C1
Qin, YH1
Jiao, HS1
Li, AS1
Jiao, Y1
Wei, LM1
Zhang, J2
Zhong, L2
Liu, K2
Zhang, XF1
Wang, X1
Zhang, X1
Qin, Y1
Dikici, S1
Kocaman, G1
Ozdem, S1
Kocer, A1
Libório, AB1
Marques, Fde O1
Testagrossa, L1
Leite, CA1
Leitão, AA1
Praxedes, JN1
White, WB1
Parke, AL1
Piratvisuth, T1
Dunne, JB1
Williams, R1
Tredger, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01738945]Phase 432 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for amlodipine and Ischemia

ArticleYear
Ramipril lowers plasma FGF-23 in patients with diabetic nephropathy.
    American journal of nephrology, 2014, Volume: 40, Issue:3

    Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type

2014

Other Studies

6 other studies available for amlodipine and Ischemia

ArticleYear
Transdermal application of azithromycin-amlodipine-heparin gel enhances survival of infected random ischaemic flap.
    Journal of plastic surgery and hand surgery, 2015, Volume: 49, Issue:6

    Topics: Administration, Cutaneous; Amlodipine; Animals; Azithromycin; Chi-Square Distribution; Drug Therapy,

2015
[Percutaneous penetration ability of dexamethasone-amlodipine besylate compound gel and its effect on survival of ischemic random skin flap].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2010, Volume: 24, Issue:5

    Topics: Amlodipine; Animals; Dexamethasone; Gels; Graft Survival; Ischemia; Rats; Rats, Sprague-Dawley; Repe

2010
Amlodipine-induced delirium in a patient with ischemic stroke.
    The neurologist, 2012, Volume: 18, Issue:3

    Topics: Amlodipine; Calcium Channel Blockers; Delirium; Humans; Ischemia; Male; Middle Aged; Stroke

2012
Malignant hypertension with intestinal ischemia secondary to juxtaglomerular cell tumor.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Abdomen, Acute; Acute Kidney Injury; Adenocarcinoma; Adult; Amlodipine; Antihypertensive Agents; Com

2005
Acute pain in the tip of the index finger.
    The American journal of medicine, 2005, Volume: 118, Issue:11

    Topics: Acute Disease; Amlodipine; Arterial Occlusive Diseases; Aspirin; Cyanosis; Diagnostic Errors; Female

2005
Amlodipine improves hepatic hemodynamic and metabolic function in the isolated perfused rat liver after sequential cold and warm ischemia.
    Transplantation, 1995, Jul-15, Volume: 60, Issue:1

    Topics: Amlodipine; Animals; Cold Temperature; Hemodynamics; Ischemia; Liver; Liver Function Tests; Male; Or

1995