amlodipine has been researched along with Hypotension in 25 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension." | 8.31 | 5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023) |
| " Amlodipine, a dihydropyridine CCB, can cause prolonged hypotension in overdose." | 7.88 | A Case of Severe, Refractory Hypotension After Amlodipine Overdose. ( Chudow, M; Ferguson, K, 2018) |
| "A 49-year-old white woman with known bilateral early optic atrophy presented to our hospital with hypotension and obtundation following a known ingestion of 150 mg of amlodipine." | 7.85 | Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report. ( Chick, G; Kao, R; Landry, Y; Leung, A, 2017) |
| "A case of acute poisoning with amlodipine with deep hypotension, transient oliguria and clinical signs of acute heart failure was described." | 7.71 | [Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine]. ( Feldman, R; Glińska-Serwin, M, 2001) |
| " Amlodipine is often favored clinically over other calcium channel blockers for its vascular selectivity and relative lack of negative ionotropy, once daily dosing and prolonged duration of effect." | 5.39 | Postoperative hypotension associated with amlodipine. ( Kadam, PG; Shah, VR, 2013) |
| "These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension." | 4.31 | 5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023) |
| " Amlodipine, a dihydropyridine CCB, can cause prolonged hypotension in overdose." | 3.88 | A Case of Severe, Refractory Hypotension After Amlodipine Overdose. ( Chudow, M; Ferguson, K, 2018) |
| "A 49-year-old white woman with known bilateral early optic atrophy presented to our hospital with hypotension and obtundation following a known ingestion of 150 mg of amlodipine." | 3.85 | Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report. ( Chick, G; Kao, R; Landry, Y; Leung, A, 2017) |
| " We report a case of persistent hypotension caused by intoxication of olmesartan and amlodipine." | 3.77 | [Case of olmesartan and amlodipine intoxication]. ( Ideno, S; Kobari, M; Nakada, T; Oiwa, T; Yaguchi, A, 2011) |
| "Amlodipine is a long-acting calcium channel blocker capable of producing hypotension and dysrhythmia in overdose." | 3.76 | Amlodipine toxicity in children less than 6 years of age: a dose-response analysis using national poison data system data. ( Bakhireva, LN; Benson, BE; Spyker, DA; Troutman, WG; Watson, WA, 2010) |
| "A case of acute poisoning with amlodipine with deep hypotension, transient oliguria and clinical signs of acute heart failure was described." | 3.71 | [Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine]. ( Feldman, R; Glińska-Serwin, M, 2001) |
| " Third-standard-dose triple antihypertensive combination therapy demonstrated early effective BP control compared to third-standard-dose dual combination therapies, without increasing adverse drug reactions in patients with mild-to-moderate hypertension." | 3.30 | Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension. ( Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC, 2023) |
| "2 years in the VALUE trial (Valsartan Antihypertensive Long-Term Use Evaluation)." | 2.94 | Blood Pressure-Lowering Profiles and Clinical Effects of Angiotensin Receptor Blockers Versus Calcium Channel Blockers. ( Berge, E; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA; Wyller, TB, 2020) |
| "Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer's disease." | 1.91 | Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats. ( Bakker, ENTP; Coolen, BF; de Vos, J; Heijst, JA; Jongenelen, CAM; Naessens, DMP; Richard, E; Scholl, ER; Strijkers, GJ; Teunissen, CE; van der Wel, NN; VanBavel, E; Wilhelmus, MMM, 2023) |
| " Insulin was infused for a total of approximately 37 hours, most of which was dosed at 10 U/kg/hour; following discontinuation, serial serum insulin levels were drawn and remained at supraphysiologic levels for at least 24 hours and well above reference range for multiple days thereafter." | 1.56 | Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report. ( Bangh, SA; Cole, JB; Corcoran, JN; Jacoby, KJ; Olives, TD, 2020) |
| " Amlodipine is often favored clinically over other calcium channel blockers for its vascular selectivity and relative lack of negative ionotropy, once daily dosing and prolonged duration of effect." | 1.39 | Postoperative hypotension associated with amlodipine. ( Kadam, PG; Shah, VR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 11 (44.00) | 24.3611 |
| 2020's | 6 (24.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, T | 1 |
| Xu, LL | 1 |
| Guo, PY | 1 |
| Shi, WT | 1 |
| Cheng, YQ | 1 |
| Liu, AJ | 1 |
| Naessens, DMP | 1 |
| de Vos, J | 1 |
| Richard, E | 1 |
| Wilhelmus, MMM | 1 |
| Jongenelen, CAM | 1 |
| Scholl, ER | 1 |
| van der Wel, NN | 1 |
| Heijst, JA | 1 |
| Teunissen, CE | 1 |
| Strijkers, GJ | 1 |
| Coolen, BF | 1 |
| VanBavel, E | 1 |
| Bakker, ENTP | 1 |
| Fukuda, N | 1 |
| Katakawa, M | 1 |
| Ito, H | 1 |
| Hara, T | 1 |
| Otsuka, N | 1 |
| Ishizuka, M | 1 |
| Abe, M | 1 |
| Sung, KC | 1 |
| Hong, SJ | 1 |
| Rhee, MY | 1 |
| Jeong, MH | 1 |
| Kim, DH | 1 |
| Lim, SW | 1 |
| Park, K | 1 |
| Lee, JB | 1 |
| Kim, SY | 1 |
| Cho, JM | 1 |
| Cho, GY | 1 |
| Heo, JH | 1 |
| Kim, SH | 1 |
| Lee, HY | 1 |
| Kim, W | 1 |
| Cho, DK | 1 |
| Park, S | 1 |
| Shin, J | 1 |
| Pyun, WB | 1 |
| Kwon, K | 1 |
| Rha, SW | 1 |
| Jung, JA | 1 |
| Mehlum, MH | 1 |
| Liestøl, K | 1 |
| Kjeldsen, SE | 1 |
| Wyller, TB | 1 |
| Julius, S | 1 |
| Rothwell, PM | 1 |
| Mancia, G | 1 |
| Parati, G | 1 |
| Weber, MA | 1 |
| Berge, E | 1 |
| Corcoran, JN | 1 |
| Jacoby, KJ | 1 |
| Olives, TD | 1 |
| Bangh, SA | 1 |
| Cole, JB | 1 |
| Chudow, M | 1 |
| Ferguson, K | 1 |
| Kao, R | 1 |
| Landry, Y | 1 |
| Chick, G | 1 |
| Leung, A | 1 |
| Zahed, NS | 1 |
| Hassanian-Moghaddam, H | 1 |
| Zamani, N | 1 |
| Raj, A | 1 |
| Panda, PK | 1 |
| Singh, SS | 1 |
| Bhatia, D | 1 |
| McDonald, MB | 1 |
| Tiyyagura, GK | 1 |
| Kondrich, J | 1 |
| Kadam, PG | 1 |
| Shah, VR | 1 |
| Brunette-Lawrey, E | 1 |
| Croft, F | 1 |
| Smith, SW | 1 |
| Ferguson, KL | 1 |
| Hoffman, RS | 3 |
| Nelson, LS | 1 |
| Greller, HA | 1 |
| Benson, BE | 1 |
| Spyker, DA | 1 |
| Troutman, WG | 1 |
| Watson, WA | 1 |
| Bakhireva, LN | 1 |
| Lugassy, DM | 1 |
| Martin, JA | 1 |
| Ideno, S | 1 |
| Nakada, T | 1 |
| Oiwa, T | 1 |
| Kobari, M | 1 |
| Yaguchi, A | 1 |
| Nimbalkar, SM | 1 |
| Patel, DV | 1 |
| Harris, NS | 1 |
| Aggarwal, C | 1 |
| Gupta, S | 1 |
| Thompson, TM | 1 |
| Bryant, SM | 1 |
| Lu, JJ | 1 |
| Kanagarajan, K | 1 |
| Marraffa, JM | 1 |
| Bouchard, NC | 1 |
| Krishnan, P | 1 |
| Stork, CM | 1 |
| Koch, AR | 1 |
| Vogelaers, DP | 1 |
| Decruyenaere, JM | 1 |
| Callens, B | 1 |
| Verstraete, A | 1 |
| Buylaert, WA | 1 |
| Cleophas, TJ | 1 |
| van der Meulen, J | 1 |
| van de Luit, L | 1 |
| Zwinderman, AH | 1 |
| Feldman, R | 1 |
| Glińska-Serwin, M | 1 |
3 trials available for amlodipine and Hypotension
| Article | Year |
|---|---|
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Thera | 2023 |
Blood Pressure-Lowering Profiles and Clinical Effects of Angiotensin Receptor Blockers Versus Calcium Channel Blockers.
Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pre | 2020 |
Daytime-selective antihypertensive activity of celiprolol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting Enzyme | 1999 |
22 other studies available for amlodipine and Hypotension
| Article | Year |
|---|---|
Synergism of amlodipine and telmisartan or candesartan on blood pressure reduction by using SynergyFinder 3.0 and probability sum test in vivo.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Hypotension; Rats; Rats, Inbred SHR; T | 2023 |
Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Atenolol; Carotid Artery, Common; Hypertension; Hypote | 2023 |
5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats.
Topics: Aminolevulinic Acid; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bupivacaine; Hype | 2023 |
Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.
Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Bradycardia; Calcium Channel Blockers; Drug Admi | 2020 |
A Case of Severe, Refractory Hypotension After Amlodipine Overdose.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Overdose; Fatal Outcome; Humans; Hypotens | 2018 |
Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report.
Topics: Amlodipine; Blindness; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Female; | 2017 |
A Fatal Case of Amlodipine Toxicity Following Iatrogenic Hypercalcemia.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Calcium Gluconate; Electrocardiography; Fatal Outcome; | 2018 |
Amlodipine (150 mg) Poisoning: A Case Study.
Topics: Adolescent; Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Hypotension; Shock; | 2018 |
Index of suspicion. Case 1: Fatigue, weakness, body aches, and metabolic alkalosis in a 15-year-old boy. Case 2: Refractory hypotension, tachycardia, hyperglycemia, and metabolic acidosis in an afebrile teen.
Topics: Acidosis; Adolescent; Alkalosis; Amlodipine; Calcium Channel Blockers; Diagnosis, Differential; Drug | 2013 |
Postoperative hypotension associated with amlodipine.
Topics: Amlodipine; Calcium Channel Blockers; Cholecystectomy, Laparoscopic; Humans; Hypotension; Male; Midd | 2013 |
Losartan and amlodipine overdose-Case Report of a patient with anuric renal failure prior to the onset of hypotension.
Topics: Acute Kidney Injury; Amlodipine; Antihypertensive Agents; Anuria; Drug Overdose; Female; Humans; Hyp | 2016 |
Prolonged severe hypotension following combined amlodipine and valsartan ingestion.
Topics: Aged; Amlodipine; Antidotes; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Cardi | 2008 |
Amlodipine toxicity in children less than 6 years of age: a dose-response analysis using national poison data system data.
Topics: Amlodipine; Calcium Channel Blockers; Child, Preschool; Databases, Factual; Dose-Response Relationsh | 2010 |
Amlodipine toxicity vs. exposure in children.
Topics: Amlodipine; Calcium Channel Blockers; Humans; Hypotension; Poison Control Centers | 2011 |
[Case of olmesartan and amlodipine intoxication].
Topics: Acid-Base Imbalance; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Calcium Gluconate; Drug Ov | 2011 |
Near fatal case of amlodipine poisoning in an infant.
Topics: Amlodipine; Calcium Channel Blockers; Drug Overdose; Glucose; Humans; Hypotension; Infant; Infusions | 2013 |
Case records of the Massachusetts General Hospital. Case 24-2006. A 40-year-old woman with hypotension after an overdose of amlodipine.
Topics: Adult; Amlodipine; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Combined Modality Therapy; | 2006 |
Case 24-2006: a woman with hypotension after an overdose of amlodipine.
Topics: Amlodipine; Calcium Channel Blockers; Humans; Hypotension; Insulin; Poisoning | 2006 |
Case 24-2006: a woman with hypotension after an overdose of amlodipine.
Topics: Amlodipine; Calcium Channel Blockers; Contraindications; Humans; Hypotension; Intestines; Poisoning; | 2006 |
The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose.
Topics: Adult; Amlodipine; Antidotes; Blood Pressure; Calcium Channel Blockers; Diazepam; Diltiazem; Drug Ov | 2007 |
Fatal intoxication with amlodipine.
Topics: Amlodipine; Fatal Outcome; Female; Humans; Hypotension; Middle Aged; Oxazepam | 1995 |
[Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine].
Topics: Adult; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Overdose; Female; Heart F | 2001 |