Page last updated: 2024-10-22

amlodipine and Hypokalemia

amlodipine has been researched along with Hypokalemia in 7 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension."9.08The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995)
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension."5.08The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995)
"Twelve patients with essential hypertension who were already on treatment with the long-acting calcium antagonist amlodipine (5 mg once daily) were entered into a double-blind, randomized crossover study of the addition of one month's treatment with either bendrofluazide (5 mg once daily) or matching placebo."5.07A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991)
"We report a case of severe hypokalemia and flaccid muscle paralysis following a suicide attempt associating the calcium channel blocker amlodipine, the antidepressant fluoxetine and barium carbonate."3.72Acute barium intoxication and hemodiafiltration. ( Appoloni, O; Haufroid, V; Koch, M; Lheureux, P; Vincent, JL, 2003)
"Hyperkalemia was associated with increased risk of combined cardiovascular disease (hazard ratio, 1."2.77Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. ( Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Eckfeldt, JH; Einhorn, PT; Ford, CE; Franklin, SS; Furberg, CD; Ong, ST; Oparil, S; Papademetriou, V; Piller, LB; Probstfield, JL, 2012)
"Adrenal hyperplasia was apparent on post-mortem histopathology."1.40Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia. ( Elwood, C; Fryers, A, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fryers, A1
Elwood, C1
Chong, SJ1
Howard, KA1
Knox, C1
Parra, D1
Rosenstein, R1
Alderman, MH1
Piller, LB1
Ford, CE1
Probstfield, JL1
Oparil, S1
Cushman, WC1
Einhorn, PT1
Franklin, SS1
Papademetriou, V1
Ong, ST1
Eckfeldt, JH1
Furberg, CD1
Calhoun, DA1
Davis, BR1
Koch, M1
Appoloni, O1
Haufroid, V1
Vincent, JL1
Lheureux, P1
Ajayi, AA1
Akintomide, AO1
Cappuccio, FP1
Markandu, ND1
Singer, DR1
Buckley, MG1
Miller, MA1
Sagnella, GA1
MacGregor, GA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000542]Phase 30 participants Interventional1993-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for amlodipine and Hypokalemia

ArticleYear
Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Chemical Analysis; Cardiovascular Diseases; Chlorth

2012
The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension.
    Journal of the National Medical Association, 1995, Volume: 87, Issue:7

    Topics: Amlodipine; Blood Pressure; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hyperte

1995
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
    American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 1

    Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Metho

1991

Other Studies

4 other studies available for amlodipine and Hypokalemia

ArticleYear
Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia.
    Journal of feline medicine and surgery, 2014, Volume: 16, Issue:10

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aldosterone; Amlodipine; Animals; Carbimazole; Cat Dis

2014
Hypokalaemia and drinking green tea: a literature review and report of 2 cases.
    BMJ case reports, 2016, Feb-16, Volume: 2016

    Topics: Aged; Amlodipine; Antihypertensive Agents; Bendroflumethiazide; Drinking Behavior; Female; Humans; H

2016
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium

2009
Acute barium intoxication and hemodiafiltration.
    Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:4

    Topics: Amlodipine; Barium; Calcium Channel Blockers; Female; Hemodiafiltration; Humans; Hypokalemia; Middle

2003