amlodipine has been researched along with Hypertrophy in 11 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amlodipine is one of the commonly prescribed antihypertensive drugs, and gingival hyperplasia is one overlooked side effect in patients taking amlodipine." | 8.12 | Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022) |
| " We have previously shown that in salt-sensitive hypertension either a statin or the calcium channel blocker amlodipine (Aml) have vasoprotective effects." | 7.80 | Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension. ( Jaimes, EA; Raij, L; Tian, R; Zhou, MS, 2014) |
| " The present study compared the effects of prolonged treatment with the Ca2+-channel blocker amlodipine and the ACE inhibitor enalapril, respectively, in TGR(mREN2)27 rats (TGR), an animal model of renin-dependent hypertension." | 7.71 | Normalisation of blood pressure in hypertensive TGR(mREN2)27 rats by amlodipine vs. enalapril: effects on cardiac hypertrophy and signal transduction pathways. ( Heckmann, M; Huser, L; Knotter, B; Lemmer, B; Schiffer, S; Witte, K, 2001) |
| "Amlodipine was found to inhibit growth and bFGF-induced DNA synthesis in a concentration-dependent manner." | 5.30 | Amlodipine and vascular hypertrophy. ( Herembert, T; Iouzalen, L; Marche, P; Stepien, O; Zhu, DL, 1997) |
| "Amlodipine is one of the commonly prescribed antihypertensive drugs, and gingival hyperplasia is one overlooked side effect in patients taking amlodipine." | 4.12 | Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022) |
| " We have previously shown that in salt-sensitive hypertension either a statin or the calcium channel blocker amlodipine (Aml) have vasoprotective effects." | 3.80 | Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension. ( Jaimes, EA; Raij, L; Tian, R; Zhou, MS, 2014) |
| "Significant reduction of aortic SMC number occurred by day 3 of amlodipine, reaching -13% at 28 days, followed by a significant regression of medial hypertrophy by day 5, reaching -13% at 28 days." | 3.74 | Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine. ( deBlois, D; Duguay, D, 2007) |
| " The present study compared the effects of prolonged treatment with the Ca2+-channel blocker amlodipine and the ACE inhibitor enalapril, respectively, in TGR(mREN2)27 rats (TGR), an animal model of renin-dependent hypertension." | 3.71 | Normalisation of blood pressure in hypertensive TGR(mREN2)27 rats by amlodipine vs. enalapril: effects on cardiac hypertrophy and signal transduction pathways. ( Heckmann, M; Huser, L; Knotter, B; Lemmer, B; Schiffer, S; Witte, K, 2001) |
| "This study investigated whether pulmonary vascular remodelling in hypoxic pulmonary hypertensive rats (10% oxygen; 4 weeks) could be prevented by treatment, during hypoxia, with amlodipine (10 mg/kg/day, p." | 3.71 | Pulmonary vascular remodelling in hypoxic rats: effects of amlodipine, alone and with perindopril. ( Jeffery, TK; Wanstall, JC, 2001) |
| " The lowest dosage of lacidipine (but not of amlodipine) restored the physiological downregulation of renin production by high salt and reduced left ventricular hypertrophy and mRNA levels of atrial natriuretic factor and transforming growth factor-beta1." | 3.71 | Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats. ( Godfraind, T; Krenek, P; Kyselovic, J; Wibo, M, 2001) |
| "Amlodipine was found to inhibit growth and bFGF-induced DNA synthesis in a concentration-dependent manner." | 1.30 | Amlodipine and vascular hypertrophy. ( Herembert, T; Iouzalen, L; Marche, P; Stepien, O; Zhu, DL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Reddy, SC | 1 |
| Midha, N | 1 |
| Chhabra, V | 1 |
| Kumar, D | 1 |
| Bohra, GK | 1 |
| Zhou, MS | 1 |
| Tian, R | 1 |
| Jaimes, EA | 1 |
| Raij, L | 1 |
| Marçal, DM | 1 |
| Rizzi, E | 1 |
| Martins-Oliveira, A | 1 |
| Ceron, CS | 1 |
| Guimaraes, DA | 1 |
| Gerlach, RF | 1 |
| Tanus-Santos, JE | 1 |
| Griffin, KA | 1 |
| Picken, M | 1 |
| Giobbie-Hurder, A | 1 |
| Bidani, AK | 1 |
| Ferrandi, M | 1 |
| Molinari, I | 1 |
| Barassi, P | 1 |
| Minotti, E | 1 |
| Bianchi, G | 1 |
| Ferrari, P | 1 |
| Duguay, D | 1 |
| deBlois, D | 1 |
| Stepien, O | 1 |
| Iouzalen, L | 1 |
| Herembert, T | 1 |
| Zhu, DL | 1 |
| Marche, P | 2 |
| Witte, K | 1 |
| Huser, L | 1 |
| Knotter, B | 1 |
| Heckmann, M | 1 |
| Schiffer, S | 1 |
| Lemmer, B | 1 |
| Jeffery, TK | 1 |
| Wanstall, JC | 1 |
| Kyselovic, J | 1 |
| Krenek, P | 1 |
| Wibo, M | 1 |
| Godfraind, T | 1 |
1 review available for amlodipine and Hypertrophy
| Article | Year |
|---|---|
[Amlodipine and the mechanisms of vascular hypertrophy].
Topics: Amlodipine; Calcium Channel Blockers; Calcium Channels; Cardiovascular Diseases; Cell Division; Huma | 2000 |
10 other studies available for amlodipine and Hypertrophy
| Article | Year |
|---|---|
Amlodipine Induced Gum Hypertrophy: A Rare Case Report.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Gingival Overgrowth; Humans; Hyper | 2022 |
Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension.
Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Atorvastatin; Blood Pressure; C-Reactive Protei | 2014 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blo | 2011 |
Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Diet, Protein-Restric | 2003 |
Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238.
Topics: Amlodipine; Androstanols; Animals; Blood Pressure; Caveolae; Enzyme Activation; Enzyme Inhibitors; H | 2004 |
Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine.
Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Hyp | 2007 |
Amlodipine and vascular hypertrophy.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cell Count; Cell Cycle; Cell Division; Cells, Culture | 1997 |
Normalisation of blood pressure in hypertensive TGR(mREN2)27 rats by amlodipine vs. enalapril: effects on cardiac hypertrophy and signal transduction pathways.
Topics: Adenylyl Cyclases; Amlodipine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Anima | 2001 |
Pulmonary vascular remodelling in hypoxic rats: effects of amlodipine, alone and with perindopril.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Heart Ventricles; Hypertension, Pulmon | 2001 |
Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats.
Topics: Actins; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Co | 2001 |