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amlodipine and Hypertension, Pulmonary

amlodipine has been researched along with Hypertension, Pulmonary in 13 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"These results show that oral amlodipine can produce acute pulmonary vasodilatation in patients with pulmonary hypertension."9.08Acute pulmonary vasodilatory properties of amlodipine in humans with pulmonary hypertension. ( Channer, KS; Morice, AH; O'Toole, L; Woodmansey, PA, 1996)
"The aim of the study was to investigate the pulmonary vasodilator effect of the dihydropyridine calcium channel blocker amlodipine in patients with clinically stable chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH)."7.71The effect of amlodipine on exercise-induced pulmonary hypertension and right heart function in patients with chronic obstructive pulmonary disease. ( Franz, IW; Schaupp, S; Tönnesmann, U; Van Der Meyden, J, 2002)
"This study was designed to evaluate the effects of amlodipine, a new calcium channel blocker, on the development of right ventricular hypertrophy and thickening of the media of the pulmonary arteries in a rat model of pulmonary hypertension."7.69Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension. ( Imai, S; Kanda, T; Kobayashi, I; Nagai, R; Suzuki, T; Takahashi, T, 1996)
"These results show that oral amlodipine can produce acute pulmonary vasodilatation in patients with pulmonary hypertension."5.08Acute pulmonary vasodilatory properties of amlodipine in humans with pulmonary hypertension. ( Channer, KS; Morice, AH; O'Toole, L; Woodmansey, PA, 1996)
"The aim of the study was to investigate the pulmonary vasodilator effect of the dihydropyridine calcium channel blocker amlodipine in patients with clinically stable chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH)."3.71The effect of amlodipine on exercise-induced pulmonary hypertension and right heart function in patients with chronic obstructive pulmonary disease. ( Franz, IW; Schaupp, S; Tönnesmann, U; Van Der Meyden, J, 2002)
"This study investigated whether pulmonary vascular remodelling in hypoxic pulmonary hypertensive rats (10% oxygen; 4 weeks) could be prevented by treatment, during hypoxia, with amlodipine (10 mg/kg/day, p."3.71Pulmonary vascular remodelling in hypoxic rats: effects of amlodipine, alone and with perindopril. ( Jeffery, TK; Wanstall, JC, 2001)
"This study was designed to evaluate the effects of amlodipine, a new calcium channel blocker, on the development of right ventricular hypertrophy and thickening of the media of the pulmonary arteries in a rat model of pulmonary hypertension."3.69Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension. ( Imai, S; Kanda, T; Kobayashi, I; Nagai, R; Suzuki, T; Takahashi, T, 1996)
" We have compared the pulmonary vasodilator effects, dose-response characteristics, and tolerability of two calcium channel blockers, amlodipine and extended-release (ER) felodipine, in 10 patients (seven men, age 68+/-4."2.68A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD. ( Alpers, JA; Bune, AJ; Frith, PA; McEvoy, RD; Sajkov, D; Wang, T, 1997)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mikhalkova, D1
Fenstad, ER1
Miller, WL1
Dmuchowska, DA1
Zalewska, R1
Jasiewicz, M1
Krasnicki, P1
Mikita, A1
Sobkowicz, B1
Mariak, Z1
Sarraf, D1
Johri, S1
Dunnington, GH1
Vnencak-Jones, CL1
Franz, IW1
Van Der Meyden, J1
Schaupp, S1
Tönnesmann, U1
Schröder, A1
Schumacher, T1
Tromm, A1
Higashide, T1
Okai, T1
Yoshida, S1
Tonoike, N1
Kakihara, M1
Mizumura, T1
Oshima, A1
Sugimura, Y1
Tamamura, T1
Ogata, I1
Mawatari, E1
Hongo, M1
Sakai, A1
Terasawa, F1
Takahashi, M1
Yazaki, Y1
Kinoshita, O1
Ikeda, U1
Woodmansey, PA2
Zhang, F1
Channer, KS2
Morice, AH2
O'Toole, L1
Takahashi, T1
Kanda, T1
Imai, S1
Suzuki, T1
Kobayashi, I1
Nagai, R1
Sajkov, D1
Wang, T1
Frith, PA1
Bune, AJ1
Alpers, JA1
McEvoy, RD1
Jeffery, TK1
Wanstall, JC1

Trials

2 trials available for amlodipine and Hypertension, Pulmonary

ArticleYear
Acute pulmonary vasodilatory properties of amlodipine in humans with pulmonary hypertension.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:2

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac

1996
A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD.
    Chest, 1997, Volume: 111, Issue:6

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Dose-Re

1997

Other Studies

11 other studies available for amlodipine and Hypertension, Pulmonary

ArticleYear
34-year-old man with exertional syncope, dyspnea, and chest pain.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:7

    Topics: Adult; Amlodipine; Antihypertensive Agents; Chest Pain; Dyspnea; Electrocardiography; Humans; Hypert

2013
Diagnostic and Therapeutic Challenges.
    Retina (Philadelphia, Pa.), 2015, Volume: 35, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Diagnosis, Differential; Drug Therapy, Combination; Female; Hum

2015
[RIGHT VENTRICULAR DIASTOLIC FUNCTION AND PERIPHERAL HEMODYNAMICS IN PATIENTS WITH CHRONIC COR PULMONALE RECEIVING VARIOUS THERAPY REGIMENS].
    Tuberkulez i bolezni legkikh, 2010, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Echocardiography, Doppler, Color; Female; Hemodynamics; Humans;

2010
A novel BMPR2 mutation associated with pulmonary arterial hypertension in an octogenarian.
    Lung, 2010, Volume: 188, Issue:4

    Topics: Aged, 80 and over; Amlodipine; Bone Morphogenetic Protein Receptors, Type II; Bosentan; Digoxin; Dys

2010
The effect of amlodipine on exercise-induced pulmonary hypertension and right heart function in patients with chronic obstructive pulmonary disease.
    Zeitschrift fur Kardiologie, 2002, Volume: 91, Issue:10

    Topics: Amlodipine; Calcium Channel Blockers; Confidence Intervals; Data Interpretation, Statistical; Exerci

2002
[Kyphoscoliosis as a cause of pulmonary hypertension].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Feb-15, Volume: 98, Issue:2

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block

2003
[Basedow disease with recurrent syncopal attack and severe pulmonary hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Apr-10, Volume: 96, Issue:4

    Topics: Aged; Amlodipine; Atrial Fibrillation; Digoxin; Female; Graves Disease; Humans; Hypertension, Pulmon

2007
Amlodipine prevents monocrotaline-induced pulmonary arterial hypertension and prolongs survival in rats independent of blood pressure lowering.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:7

    Topics: Amlodipine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Blotting, We

2007
Vasodilatory action of the calcium antagonist amlodipine on large and resistance pulmonary arteries from normoxic and chronically hypoxic rats.
    Clinical science (London, England : 1979), 1993, Volume: 85, Issue:3

    Topics: Amlodipine; Animals; Aorta; Chronic Disease; Dose-Response Relationship, Drug; Hypertension, Pulmona

1993
Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 91, Issue:1

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Hypertension, Pulmonary; Hypertrophy, Right Ventricul

1996
Pulmonary vascular remodelling in hypoxic rats: effects of amlodipine, alone and with perindopril.
    European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Heart Ventricles; Hypertension, Pulmon

2001