Page last updated: 2024-10-22

amlodipine and Hyperinsulinism

amlodipine has been researched along with Hyperinsulinism in 4 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.

Research Excerpts

ExcerptRelevanceReference
" Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock."8.12Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022)
"we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia."7.73[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005)
" Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock."4.12Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022)
"we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia."3.73[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005)
" Insulin was infused for a total of approximately 37 hours, most of which was dosed at 10 U/kg/hour; following discontinuation, serial serum insulin levels were drawn and remained at supraphysiologic levels for at least 24 hours and well above reference range for multiple days thereafter."1.56Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report. ( Bangh, SA; Cole, JB; Corcoran, JN; Jacoby, KJ; Olives, TD, 2020)
"Rosiglitazone-treated rats had restored systolic blood pressure (BP) and normalized plasma insulin level during oral glucose tolerance tests, whereas amlodipine-treated rats restored only systolic BP."1.35Myocardial heat shock protein 60 expression in insulin-resistant and diabetic rats. ( Chen, HS; Juan, CC; Lin, HD; Wu, TE, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Koliastasis, L1
Lampadakis, I1
Milkas, A1
Strempelas, P1
Sourides, V1
Kakava, K1
Tsioufis, P1
Papaioannou, S1
Corcoran, JN1
Jacoby, KJ1
Olives, TD1
Bangh, SA1
Cole, JB1
Chen, HS1
Wu, TE1
Juan, CC1
Lin, HD1
Owecki, M1
Sowiński, J1

Other Studies

4 other studies available for amlodipine and Hyperinsulinism

ArticleYear
Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia.
    Cardiovascular toxicology, 2022, Volume: 22, Issue:1

    Topics: Aged; Amlodipine; Calcium Channel Blockers; COVID-19; Drug Overdose; Female; Humans; Hyperinsulinism

2022
Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Bradycardia; Calcium Channel Blockers; Drug Admi

2020
Myocardial heat shock protein 60 expression in insulin-resistant and diabetic rats.
    The Journal of endocrinology, 2009, Volume: 200, Issue:2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Chaperonin 60; Diabetes Mellitus, Experimental; Diseas

2009
[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005, Volume: 19, Issue:110

    Topics: Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Female; Humans; Hyperinsulinism; Hypertensi

2005