Page last updated: 2024-10-22

amlodipine and Hyperhomocysteinemia

amlodipine has been researched along with Hyperhomocysteinemia in 3 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (

Research Excerpts

ExcerptRelevanceReference
"Hyperhomocysteinemia with hypertension can synergistically increase the risk of stroke."9.69Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized, ( Bao, H; Chen, G; Cheng, X; Cheng, Z; Cui, Y; Ding, C; Hu, L; Huang, X; Huo, Y; Li, P; Qin, X; Sheng, C; Song, D; Tang, G; Wang, J; Wang, X; Wang, Z; Yao, C; Zhang, J, 2023)
"Hypertension and hyperhomocysteinemia (HHcy) have long been associated with adverse cardiovascular and cerebrovascular health outcomes."9.51Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study. ( He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S, 2022)
"Hyperhomocysteinemia with hypertension can synergistically increase the risk of stroke."5.69Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized, ( Bao, H; Chen, G; Cheng, X; Cheng, Z; Cui, Y; Ding, C; Hu, L; Huang, X; Huo, Y; Li, P; Qin, X; Sheng, C; Song, D; Tang, G; Wang, J; Wang, X; Wang, Z; Yao, C; Zhang, J, 2023)
"Hypertension and hyperhomocysteinemia (HHcy) have long been associated with adverse cardiovascular and cerebrovascular health outcomes."5.51Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study. ( He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S, 2022)
"To investigate the actions of amlodipine-folic acid (amlodipine-FA) preparation on hypertension and cardiovascular in renal hypertensive rats with hyperhomocysteinemia (HHcy), so as to provide experimental basis for clinical research of amlodipine folic acid tablets."4.31Folic acid enhances the cardiovascular protective effect of amlodipine in renal hypertensive rats with elevated homocysteine. ( Chen, GL; Li, L; Liu, H; Lv, L; Ma, Z; Tong, X, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Zhang, S1
Wang, T1
Wang, H1
Tang, J1
Hou, A1
Yan, X1
Yu, B1
Ran, S1
Luo, M1
Tang, Y1
Yang, R1
Song, D2
He, H1
Li, L1
Tong, X1
Ma, Z1
Lv, L1
Liu, H1
Chen, GL1
Bao, H1
Huang, X1
Li, P1
Sheng, C1
Zhang, J1
Wang, Z1
Hu, L1
Ding, C1
Cheng, Z1
Yao, C1
Chen, G1
Cui, Y1
Qin, X1
Tang, G1
Wang, X1
Huo, Y1
Cheng, X1
Wang, J1

Trials

2 trials available for amlodipine and Hyperhomocysteinemia

ArticleYear
Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study.
    Medicine, 2022, Jan-21, Volume: 101, Issue:3

    Topics: Amlodipine; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Fe

2022
Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized,
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:8

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Folic Aci

2023

Other Studies

1 other study available for amlodipine and Hyperhomocysteinemia

ArticleYear
Folic acid enhances the cardiovascular protective effect of amlodipine in renal hypertensive rats with elevated homocysteine.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2023, Dec-31, Volume: 45, Issue:1

    Topics: Amlodipine; Animals; Endothelial Cells; Folic Acid; Homocysteine; Hyperhomocysteinemia; Hypertension

2023