Page last updated: 2024-10-22

amlodipine and Hyperemia

amlodipine has been researched along with Hyperemia in 7 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that the ACE inhibitor imidapril augments RH after 12 weeks of treatment in patients with essential hypertension and that this ACE inhibitor-induced augmentation of RH may be due to an increase in NO."7.71Effect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: relationship between treatment periods and resistance artery endothelial function. ( Higashi, Y; Kajiyama, G; Matsuura, H; Nakagawa, K; Oshima, T; Sasaki, S, 2001)
" Forearm blood flow (FBF) was measured in 69 patients with essential hypertension (mild, n = 23; moderate, n = 29; and severe, n = 17 randomly assigned to treatment with either imidapril or amlodipine for 24 weeks in a double-blind fashion during reactive hyperemia and after sublingual administration of nitroglycerin."5.10Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition. ( Chayama, K; Goto, C; Hara, K; Higashi, Y; Kimura, M; Matsuura, H; Nakagawa, K; Noma, K; Oshima, T; Sasaki, S, 2002)
"These findings suggest that the ACE inhibitor imidapril augments RH after 12 weeks of treatment in patients with essential hypertension and that this ACE inhibitor-induced augmentation of RH may be due to an increase in NO."3.71Effect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: relationship between treatment periods and resistance artery endothelial function. ( Higashi, Y; Kajiyama, G; Matsuura, H; Nakagawa, K; Oshima, T; Sasaki, S, 2001)
"Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear."1.62Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. ( Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC, 2021)
"Forearm vasodilatory response to reactive hyperemia was improved by temocapril (102 +/- 20% to 168 +/- 25%, P < ."1.30Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension. ( Hata, T; Higaki, J; Iwatsubo, H; Kumamoto, K; Morita, R; Nagano, M; Ogihara, T; Sakai, T, 1997)
" The chronic administration of benazepril (5-10 mg/d) for 20 weeks improved insulin sensitivity, endothelial function (6."1.30Relationship between endothelial function and fibrinolysis in early hypertension. ( Doba, N; Kimura, Y; Kinouchi, T; Kushiro, T; Mitsuhashi, H; Tomiyama, H; Yoshida, H, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Koide, M1
Harraz, OF1
Dabertrand, F1
Longden, TA1
Ferris, HR1
Wellman, GC1
Hill-Eubanks, DC1
Greenstein, AS1
Nelson, MT1
Felmeden, DC1
Blann, AD1
Spencer, CG1
Beevers, DG1
Lip, GY1
Okuro, M1
Morimoto, S1
Takahashi, T1
Okaishi, K1
Nakahashi, T1
Murai, H1
Iwai, K1
Kanda, T1
Matsumoto, M1
Iwatsubo, H1
Nagano, M1
Sakai, T1
Kumamoto, K1
Morita, R1
Higaki, J1
Ogihara, T1
Hata, T1
Tomiyama, H1
Kimura, Y1
Mitsuhashi, H1
Kinouchi, T1
Yoshida, H1
Kushiro, T1
Doba, N1
Higashi, Y2
Sasaki, S3
Nakagawa, K2
Matsuura, H2
Kajiyama, G1
Oshima, T2
Kimura, M1
Noma, K1
Hara, K1
Goto, C1
Chayama, K1

Trials

3 trials available for amlodipine and Hyperemia

ArticleYear
A comparison of flow-mediated dilatation and von Willebrand factor as markers of endothelial cell function in health and in hypertension: relationship to cardiovascular risk and effects of treatment: a substudy of the Anglo-Scandinavian Cardiac Outcomes T
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2003, Volume: 14, Issue:5

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atenolol; Brachial Artery; Card

2003
Angiotensin I-converting enzyme inhibitor improves reactive hyperemia in elderly hypertensives with arteriosclerosis obliterans.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Arteriosclerosis Obli

2006
Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:5

    Topics: Adult; Amlodipine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2002

Other Studies

4 other studies available for amlodipine and Hyperemia

ArticleYear
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.
    The Journal of clinical investigation, 2021, 09-15, Volume: 131, Issue:18

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cerebral Smal

2021
Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calci

1997
Relationship between endothelial function and fibrinolysis in early hypertension.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Brachial

1998
Effect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: relationship between treatment periods and resistance artery endothelial function.
    Journal of the American College of Cardiology, 2001, Mar-01, Volume: 37, Issue:3

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Endothelium, Vascular; Female; Forearm;

2001