amlodipine has been researched along with Heart Diseases in 10 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is lacking evidence that telmisartan can improve insulin resistance in patients on high-intensity statins." | 5.51 | Effects of high-intensity statin combined with telmisartan versus amlodipine on glucose metabolism in hypertensive atherosclerotic cardiovascular disease patients with impaired fasting glucose: A randomized multicenter trial. ( Kang, TS; Kim, BK; Kim, JY; Lee, CJ; Lee, SH; Park, S; Sung, JH, 2022) |
| " The purpose of the present study was to evaluate therapeutic effect and possible mechanism of action of amlodipine, one of the widely used CCBs, on rat cardiac dysfunction during sepsis induced by lipopolysaccharide (LPS)." | 3.75 | Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway. ( Cao, W; Hao, LL; Li, T; Li, XQ; Mei, QB; Zeng, AG; Zhang, XN, 2009) |
| "The treatment with amlodipine reduced SBP but failed to ameliorate the ADMA-induced histological changes." | 1.34 | Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. ( Hasegawa, K; Hayashi, K; Homma, K; Itoh, H; Kimoto, M; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K, 2007) |
| "Heart failure was four times more frequent in these patients with renal disease than in other hypertensives." | 1.33 | [Coronary disease risk and prevalence of heart disease in primary care patients with hypertension and renal disease]. ( Aguilar-Llopis, A; Arístegui-Urrestarazu, R; Cosín-Aguilar, J; Hernándiz-Martínez, A; Masramón-Morell, X; Rodríguez-Padial, L; Zamorano-Gómez, JL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CJ | 1 |
| Sung, JH | 1 |
| Kang, TS | 1 |
| Park, S | 1 |
| Lee, SH | 1 |
| Kim, JY | 1 |
| Kim, BK | 1 |
| Li, XQ | 1 |
| Cao, W | 1 |
| Li, T | 1 |
| Zeng, AG | 1 |
| Hao, LL | 1 |
| Zhang, XN | 1 |
| Mei, QB | 1 |
| Lopatin, IuM | 1 |
| Wilson, SA | 1 |
| Sanford, A | 1 |
| Cosín-Aguilar, J | 1 |
| Hernándiz-Martínez, A | 1 |
| Arístegui-Urrestarazu, R | 1 |
| Masramón-Morell, X | 1 |
| Aguilar-Llopis, A | 1 |
| Rodríguez-Padial, L | 1 |
| Zamorano-Gómez, JL | 1 |
| Messerli, FH | 1 |
| Hasegawa, K | 1 |
| Wakino, S | 1 |
| Tatematsu, S | 1 |
| Yoshioka, K | 1 |
| Homma, K | 1 |
| Sugano, N | 1 |
| Kimoto, M | 1 |
| Hayashi, K | 1 |
| Itoh, H | 1 |
| Margolis, KL | 1 |
| Piller, LB | 1 |
| Ford, CE | 1 |
| Henriquez, MA | 1 |
| Cushman, WC | 1 |
| Einhorn, PT | 1 |
| Colon, PJ | 1 |
| Vidt, DG | 1 |
| Christian, R | 1 |
| Wong, ND | 1 |
| Wright, JT | 1 |
| Goff, DC | 1 |
| Dollé, F | 1 |
| Hinnen, F | 1 |
| Valette, H | 1 |
| Fuseau, C | 1 |
| Duval, R | 1 |
| Péglion, JL | 1 |
| Crouzel, C | 1 |
| Pahor, M | 1 |
| Tatti, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amlodipine and Heart Diseases
| Article | Year |
|---|---|
Amlodipine/atorvastatin (Caduet) for preventing heart disease.
Topics: Amlodipine; Drug Combinations; Heart Diseases; Heptanoic Acids; Humans; Pyrroles; Treatment Outcome | 2006 |
3 trials available for amlodipine and Heart Diseases
| Article | Year |
|---|---|
Effects of high-intensity statin combined with telmisartan versus amlodipine on glucose metabolism in hypertensive atherosclerotic cardiovascular disease patients with impaired fasting glucose: A randomized multicenter trial.
Topics: Amlodipine; Atherosclerosis; Cardiovascular Diseases; Fasting; Glucose; Heart Diseases; Humans; Hydr | 2022 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal | 2007 |
The Fosinopril versus Amlodipine Cardiovascular Events Trial (FACET) and combination therapies.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block | 1999 |
6 other studies available for amlodipine and Heart Diseases
| Article | Year |
|---|---|
Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway.
Topics: Amlodipine; Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Cells, Cultured; Gene Expre | 2009 |
[How to increase the adherence to treatment of patients with arterial hypertension and dyslipidemia: focus on fixed combination of amlodipine and atorvastatin].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic | 2010 |
[Coronary disease risk and prevalence of heart disease in primary care patients with hypertension and renal disease].
Topics: Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Coronary Di | 2006 |
Amlodipine/atorvastatin for preventing heart disease.
Topics: Amlodipine; Anticholesteremic Agents; Atorvastatin; Drug Combinations; Heart Diseases; Heptanoic Aci | 2007 |
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
Topics: Amidohydrolases; Amlodipine; Angiotensin II; Animals; Arginine; Blood Pressure; Coronary Circulation | 2007 |
Synthesis of two optically active calcium channel antagonists labelled with carbon-11 for in vivo cardiac PET imaging.
Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Carbon Radioisotopes; Chromatog | 1997 |