Page last updated: 2024-10-22

amlodipine and HIV Infections

amlodipine has been researched along with HIV Infections in 5 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

HIV Infections: Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).

Research Excerpts

ExcerptRelevanceReference
"Gynecomastia is known to occur in some men taking an efavirenz-based antiretroviral therapy (ART) regimen."7.91Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe. ( Chimbetete, C; Shamu, T; Shawarira-Bote, S, 2019)
"Gynecomastia is known to occur in some men taking an efavirenz-based antiretroviral therapy (ART) regimen."3.91Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe. ( Chimbetete, C; Shamu, T; Shawarira-Bote, S, 2019)
" We evaluated potential bidirectional pharmacokinetic interactions between calcium channel blockers and coadministered indinavir and ritonavir."2.71Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers. ( Aberg, JA; Fichtenbaum, CJ; Gerber, JG; Glesby, MJ; Grosskopf, N; Hafner, R; Hall, S; Kendall, MA; Zolopa, AR, 2005)
": The risk of drug-drug interactions (DDIs) is elevated in aging people living with HIV (PLWH) because of highly prevalent age-related comorbidities leading to more comedications."1.56Aging does not impact drug--drug interaction magnitudes with antiretrovirals. ( Battegay, M; Cavassini, M; Courlet, P; Decosterd, L; Marzolini, C; Saldanha, SA; Stader, F; Stoeckle, M, 2020)
" As the management of drug-drug interactions (DDIs) constitutes a key aspect of the care of PLWH, the magnitude of pharmacokinetic DDIs between cardiovascular and anti-HIV drugs needs to be more thoroughly characterized."1.51UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV. ( Alves Saldanha, S; Buclin, T; Cavassini, M; Courlet, P; Csajka, C; Decosterd, LA; Desfontaine, V; Marzolini, C; Spaggiari, D, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Shawarira-Bote, S1
Shamu, T1
Chimbetete, C1
Stader, F1
Decosterd, L1
Stoeckle, M1
Cavassini, M2
Battegay, M1
Saldanha, SA1
Marzolini, C2
Courlet, P2
Spaggiari, D1
Desfontaine, V1
Alves Saldanha, S1
Buclin, T1
Csajka, C1
Decosterd, LA1
Singh, GJ1
Jackson, A1
D'Avolio, A1
Else, L1
De Nicolò, A1
Bonora, S1
Di Perri, G1
Khoo, S1
Back, D1
Moyle, G1
Boffito, M1
Glesby, MJ1
Aberg, JA1
Kendall, MA1
Fichtenbaum, CJ1
Hafner, R1
Hall, S1
Grosskopf, N1
Zolopa, AR1
Gerber, JG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Potential Pharmacokinetic Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers[NCT00039975]Phase 132 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for amlodipine and HIV Infections

ArticleYear
Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Amlodipine; Calcium Channel Blockers; Diltiazem; Drug Interactions; Drug Therapy,

2005

Other Studies

4 other studies available for amlodipine and HIV Infections

ArticleYear
Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe.
    BMC infectious diseases, 2019, Aug-13, Volume: 19, Issue:1

    Topics: Adult; Alkynes; Amlodipine; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyc

2019
Aging does not impact drug--drug interaction magnitudes with antiretrovirals.
    AIDS (London, England), 2020, 05-01, Volume: 34, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Amlodipine; Anti-Retroviral Agents; Antiretroviral Therapy, Highly A

2020
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, 09-01, Volume: 1125

    Topics: Amlodipine; Anti-HIV Agents; Atorvastatin; Chromatography, High Pressure Liquid; Drug Interactions;

2019
No pharmacokinetic interaction between raltegravir and amlodipine: importance for co-prescribing in ageing HIV-infected individuals.
    AIDS (London, England), 2014, Aug-24, Volume: 28, Issue:13

    Topics: Adult; Amlodipine; Anti-HIV Agents; Antihypertensive Agents; Chromatography, Liquid; Cross-Over Stud

2014