amlodipine has been researched along with Gestational Hypertension in 6 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the maternal and neonatal efficacy and safety with furosemide, amlodipine or aspirin in women with mild/moderate chronic hypertension during pregnancy." | 9.19 | Management of chronic hypertension during pregnancy with furosemide, amlodipine or aspirin: a pilot clinical trial. ( Dominguez, L; Solis, A; Vigil-De Gracia, P, 2014) |
| "The aims of this study were to evaluate the plasma concentration of amlodipine and its passage into breast milk in lactating women with pregnancy-induced hypertension and to estimate the risk for breastfeeding infants." | 7.81 | Amlodipine passage into breast milk in lactating women with pregnancy-induced hypertension and its estimation of infant risk for breastfeeding. ( Deguchi, S; Itoh, H; Kanayama, N; Kawakami, J; Kubono, N; Naito, T; Sugihara, M, 2015) |
| "To determine the maternal and neonatal efficacy and safety with furosemide, amlodipine or aspirin in women with mild/moderate chronic hypertension during pregnancy." | 5.19 | Management of chronic hypertension during pregnancy with furosemide, amlodipine or aspirin: a pilot clinical trial. ( Dominguez, L; Solis, A; Vigil-De Gracia, P, 2014) |
| "Amlodipine is rarely used in the treatment of pregnant hypertensive women due to limited pharmacokinetic data during pregnancy and the postpartum period." | 3.88 | Pharmacokinetics of amlodipine besylate at delivery and during lactation. ( Kogutt, BK; McIntire, DD; Meek, C; Morgan, JL; Roberts, SW; Sheffield, JS; Stehel, EK, 2018) |
| "The aims of this study were to evaluate the plasma concentration of amlodipine and its passage into breast milk in lactating women with pregnancy-induced hypertension and to estimate the risk for breastfeeding infants." | 3.81 | Amlodipine passage into breast milk in lactating women with pregnancy-induced hypertension and its estimation of infant risk for breastfeeding. ( Deguchi, S; Itoh, H; Kanayama, N; Kawakami, J; Kubono, N; Naito, T; Sugihara, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T | 1 |
| Nishigori, H | 1 |
| Akazawa, M | 1 |
| Miyakoda, K | 1 |
| Noda, A | 1 |
| Ishikuro, M | 1 |
| Metoki, H | 1 |
| Iwama, N | 1 |
| Saito, M | 1 |
| Sugawara, J | 1 |
| Kawame, H | 1 |
| Yaegashi, N | 1 |
| Kuriyama, S | 1 |
| Mano, N | 1 |
| Obara, T | 1 |
| Morgan, JL | 1 |
| Kogutt, BK | 1 |
| Meek, C | 1 |
| Stehel, EK | 1 |
| McIntire, DD | 1 |
| Sheffield, JS | 1 |
| Roberts, SW | 1 |
| Vigil-De Gracia, P | 1 |
| Dominguez, L | 1 |
| Solis, A | 1 |
| Naito, T | 2 |
| Kubono, N | 2 |
| Deguchi, S | 2 |
| Sugihara, M | 2 |
| Itoh, H | 2 |
| Kanayama, N | 2 |
| Kawakami, J | 2 |
| Ishida, T | 1 |
| Ahn, HK | 1 |
| Nava-Ocampo, AA | 1 |
| Han, JY | 1 |
| Choi, JS | 1 |
| Chung, JH | 1 |
| Yang, JH | 1 |
| Koong, MK | 1 |
| Park, CT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension: A Randomized Controlled Noninferiority Trial[NCT04790279] | Phase 4 | 132 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| Cholesterol and CYP3A4/5 Metabolism Across Pregnancy and Postpartum[NCT05504889] | 36 participants (Actual) | Observational | 2022-06-17 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for amlodipine and Gestational Hypertension
| Article | Year |
|---|---|
Management of chronic hypertension during pregnancy with furosemide, amlodipine or aspirin: a pilot clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Aspirin; Diuretics; Female; Furosemide; Humans; Hyperten | 2014 |
5 other studies available for amlodipine and Gestational Hypertension
| Article | Year |
|---|---|
Risk of major congenital malformations associated with first-trimester antihypertensives, including amlodipine and methyldopa: A large claims database study 2010-2019.
Topics: Amlodipine; Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Male; Methyldo | 2023 |
Pharmacokinetics of amlodipine besylate at delivery and during lactation.
Topics: Adult; Amlodipine; Antihypertensive Agents; Chronic Disease; Delivery, Obstetric; Drug Monitoring; F | 2018 |
Amlodipine passage into breast milk in lactating women with pregnancy-induced hypertension and its estimation of infant risk for breastfeeding.
Topics: Administration, Oral; Adult; Amlodipine; Antihypertensive Agents; Breast Feeding; Female; Humans; Hy | 2015 |
CYP3A activity based on plasma 4β-hydroxycholesterol during the early postpartum period has an effect on the plasma disposition of amlodipine.
Topics: Adult; Amlodipine; Antihypertensive Agents; Biomarkers; Biotransformation; Calcium Channel Blockers; | 2015 |
Exposure to amlodipine in the first trimester of pregnancy and during breastfeeding.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Breast Feeding; Calcium Channel Blockers | 2007 |