Page last updated: 2024-10-22

amlodipine and Genetic Predisposition

amlodipine has been researched along with Genetic Predisposition in 3 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Research Excerpts

ExcerptRelevanceReference
"Amlodipine is generally safe in subjects with HP and does not increase pain or episodes of AP."9.12Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis. ( Elinoff, BD; Lowe, ME; Morinville, VD; Whitcomb, DC, 2007)
"Amlodipine is generally safe in subjects with HP and does not increase pain or episodes of AP."5.12Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis. ( Elinoff, BD; Lowe, ME; Morinville, VD; Whitcomb, DC, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Stone, IB1
Green, JAEM1
Koefoed, AW1
Hornik, ES1
Williams, JS1
Adler, GK1
Williams, GH1
Davis, BR1
Arnett, DK1
Boerwinkle, E1
Ford, CE1
Leiendecker-Foster, C1
Miller, MB1
Black, H1
Eckfeldt, JH1
Morinville, VD1
Lowe, ME1
Elinoff, BD1
Whitcomb, DC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055]Phase 475 participants (Anticipated)Interventional2023-08-25Recruiting
Salt Sensitive Hypertension and Striatin[NCT03683069]Phase 4400 participants (Actual)Interventional2019-01-15Active, not recruiting
GenHAT - Genetics of Hypertension Associated Treatments - Ancillary to ALLHAT[NCT00563901]37,939 participants (Actual)Observational2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for amlodipine and Genetic Predisposition

ArticleYear
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
    The pharmacogenomics journal, 2007, Volume: 7, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalido

2007
Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis.
    Pancreas, 2007, Volume: 35, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Amlodipine; Analgesics; Blood Pressure; Calcium Channel Blockers;

2007