amlodipine has been researched along with Fatigue in 5 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-10 mg) once daily was compared with atenolol (50-100 mg) once daily in patients with mild-to-moderate essential hypertension in a randomized, double-blind, parallel, placebo-controlled study." | 9.07 | Amlodipine versus atenolol in essential hypertension. ( Brobyn, R; Brown, RD; Frishman, WH; Johnson, BF; Reeves, RL; Wombolt, DG, 1994) |
| " Both treatment groups had similar adverse event rates (35." | 6.76 | Comparative efficacy and safety of combination aliskiren/amlodipine and amlodipine monotherapy in African Americans with stage 2 hypertension. ( Black, HR; Hilkert, R; Israel, M; Izzo, J; Lee, J; Purkayastha, D; Sridharan, K; Weinberger, MH, 2011) |
| "5-10 mg) once daily was compared with atenolol (50-100 mg) once daily in patients with mild-to-moderate essential hypertension in a randomized, double-blind, parallel, placebo-controlled study." | 5.07 | Amlodipine versus atenolol in essential hypertension. ( Brobyn, R; Brown, RD; Frishman, WH; Johnson, BF; Reeves, RL; Wombolt, DG, 1994) |
| " Both treatment groups had similar adverse event rates (35." | 2.76 | Comparative efficacy and safety of combination aliskiren/amlodipine and amlodipine monotherapy in African Americans with stage 2 hypertension. ( Black, HR; Hilkert, R; Israel, M; Izzo, J; Lee, J; Purkayastha, D; Sridharan, K; Weinberger, MH, 2011) |
| "Treatment with amlodipine either as monotherapy or combined with other antianginal therapy for up to 26 weeks shows that efficacy is maintained, with no evidence of tolerance." | 2.67 | Amlodipine once a day in stable angina: double-blind crossover comparison with placebo. ( Cheitlin, MD; Das, SK; Deedwania, PC; Pasternak, RC; Pool, PE; Singh, JB, 1993) |
| "Amlodipine treatment was associated with a slightly higher incidence of side effects compared with placebo, but most of this difference was the result of edema, which was usually well tolerated." | 2.66 | The safety of amlodipine. ( Osterloh, I, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatia, D | 1 |
| McDonald, MB | 1 |
| Tiyyagura, GK | 1 |
| Kondrich, J | 1 |
| Black, HR | 1 |
| Weinberger, MH | 1 |
| Purkayastha, D | 1 |
| Lee, J | 1 |
| Sridharan, K | 1 |
| Israel, M | 1 |
| Hilkert, R | 1 |
| Izzo, J | 1 |
| Frishman, WH | 1 |
| Brobyn, R | 1 |
| Brown, RD | 1 |
| Johnson, BF | 1 |
| Reeves, RL | 1 |
| Wombolt, DG | 1 |
| Deedwania, PC | 1 |
| Cheitlin, MD | 1 |
| Das, SK | 1 |
| Pool, PE | 1 |
| Singh, JB | 1 |
| Pasternak, RC | 1 |
| Osterloh, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for amlodipine and Fatigue
| Article | Year |
|---|---|
Comparative efficacy and safety of combination aliskiren/amlodipine and amlodipine monotherapy in African Americans with stage 2 hypertension.
Topics: Adult; Amides; Amlodipine; Black or African American; Blood Pressure; Blood Pressure Monitoring, Amb | 2011 |
Amlodipine versus atenolol in essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Atenolol; Blood Pressure; Double-Blind Method; Drug Administrat | 1994 |
Amlodipine once a day in stable angina: double-blind crossover comparison with placebo.
Topics: Aged; Amlodipine; Angina Pectoris; Double-Blind Method; Electrocardiography; Exercise Test; Fatigue; | 1993 |
The safety of amlodipine.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; D | 1989 |
1 other study available for amlodipine and Fatigue
| Article | Year |
|---|---|
Index of suspicion. Case 1: Fatigue, weakness, body aches, and metabolic alkalosis in a 15-year-old boy. Case 2: Refractory hypotension, tachycardia, hyperglycemia, and metabolic acidosis in an afebrile teen.
Topics: Acidosis; Adolescent; Alkalosis; Amlodipine; Calcium Channel Blockers; Diagnosis, Differential; Drug | 2013 |