amlodipine has been researched along with Drug Overdose in 47 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock." | 8.12 | Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022) |
| " Amlodipine, a dihydropyridine CCB, can cause prolonged hypotension in overdose." | 7.88 | A Case of Severe, Refractory Hypotension After Amlodipine Overdose. ( Chudow, M; Ferguson, K, 2018) |
| "A 49-year-old white woman with known bilateral early optic atrophy presented to our hospital with hypotension and obtundation following a known ingestion of 150 mg of amlodipine." | 7.85 | Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report. ( Chick, G; Kao, R; Landry, Y; Leung, A, 2017) |
| "A case of acute poisoning with amlodipine with deep hypotension, transient oliguria and clinical signs of acute heart failure was described." | 7.71 | [Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine]. ( Feldman, R; Glińska-Serwin, M, 2001) |
| " Amlodipine is a long-acting dihydropyridine and inappropriate dosage poses a great threat for profound vasodilation, hypotension, and refractory vasopressor-resistant shock." | 4.12 | Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia. ( Kakava, K; Koliastasis, L; Lampadakis, I; Milkas, A; Papaioannou, S; Sourides, V; Strempelas, P; Tsioufis, P, 2022) |
| "Amlodipine overdoses have significant cardiac toxicity and are difficult to treat." | 4.02 | Efficacy of methylene blue in a murine model of amlodipine overdose. ( Baccanale, CL; de Castro Brás, LE; Eccleston, L; Meggs, WJ; O'Rourke, D; Pittman, P; Sloan, T; St Antoine, JC; Verzwyvelt, SM, 2021) |
| " Amlodipine, a dihydropyridine CCB, can cause prolonged hypotension in overdose." | 3.88 | A Case of Severe, Refractory Hypotension After Amlodipine Overdose. ( Chudow, M; Ferguson, K, 2018) |
| "A 49-year-old white woman with known bilateral early optic atrophy presented to our hospital with hypotension and obtundation following a known ingestion of 150 mg of amlodipine." | 3.85 | Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report. ( Chick, G; Kao, R; Landry, Y; Leung, A, 2017) |
| "We describe the case of a 58-year-old woman who developed a severe distributive shock following the intentional ingestion of a large overdose of amlodipine (480 mg) combined with valsartan (3680 mg)." | 3.81 | Mixed amlodipine/valsartan overdose treated by the molecular adsorbent recirculating system (MARS™). ( Capron, A; Galloy, AC; Gérard, L; Hantson, P, 2015) |
| " We describe a rare case of massive overdose of lercanidipine with shock, refractory to conventional therapies and multi-organ failure." | 3.80 | Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose. ( Javeri, Y; Juneja, D; Nasa, P; Singh, A; Singh, O, 2014) |
| " We report a case of persistent hypotension caused by intoxication of olmesartan and amlodipine." | 3.77 | [Case of olmesartan and amlodipine intoxication]. ( Ideno, S; Kobari, M; Nakada, T; Oiwa, T; Yaguchi, A, 2011) |
| "A case of acute poisoning with amlodipine with deep hypotension, transient oliguria and clinical signs of acute heart failure was described." | 3.71 | [Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine]. ( Feldman, R; Glińska-Serwin, M, 2001) |
| "Amlodipine is a dihydropyridine calcium channel blocker used in the treatment of hypertension and angina pectoris." | 2.48 | Amlodipine fatality in an infant with postmortem blood levels. ( Bosse, GM; Milliner, BA; Spiller, HA, 2012) |
| " Insulin was infused for a total of approximately 37 hours, most of which was dosed at 10 U/kg/hour; following discontinuation, serial serum insulin levels were drawn and remained at supraphysiologic levels for at least 24 hours and well above reference range for multiple days thereafter." | 1.56 | Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report. ( Bangh, SA; Cole, JB; Corcoran, JN; Jacoby, KJ; Olives, TD, 2020) |
| " Different dosing regimens have been employed." | 1.34 | Acute amlodipine overdose treated by high dose intravenous calcium in a patient with severe renal insufficiency. ( Hung, YM; Olson, KR, 2007) |
| "Amlodipine was measured by liquid chromatography-atmospheric pressure photoionization-mass spectrometry." | 1.33 | Two cases of fatal amlodipine overdose. ( Aronica-Pollack, PA; Fowler, D; Ingwersen, KM; Levine, B; Sklerov, JH, 2006) |
| "Amlodipine is a relatively new agent that has the longest half-life of all calcium channel blockers." | 1.30 | Amlodipine overdose causes prolonged calcium channel blocker toxicity. ( Adams, BD; Browne, WT, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.26) | 18.2507 |
| 2000's | 15 (31.91) | 29.6817 |
| 2010's | 22 (46.81) | 24.3611 |
| 2020's | 8 (17.02) | 2.80 |
| Authors | Studies |
|---|---|
| Koliastasis, L | 1 |
| Lampadakis, I | 1 |
| Milkas, A | 1 |
| Strempelas, P | 1 |
| Sourides, V | 1 |
| Kakava, K | 1 |
| Tsioufis, P | 1 |
| Papaioannou, S | 1 |
| Garay Bobadilla, DS | 1 |
| Núñez, JP | 1 |
| Montenegro Urquieta, AM | 1 |
| Motto, E | 1 |
| Rivello, G | 1 |
| Selandari, J | 1 |
| Flores Tonfi, L | 1 |
| Osman, AF | 1 |
| Prasad, RM | 1 |
| Marein, S | 1 |
| O'Brien, C | 1 |
| Hong, IZ | 1 |
| Ng, M | 1 |
| Sewa, DW | 1 |
| Yao, YJ | 1 |
| Jose, MC | 1 |
| Tan, KBK | 1 |
| Ponampalam, R | 1 |
| Ando, M | 1 |
| Nakasako, S | 1 |
| Ariyoshi, K | 1 |
| Yamaguchi, M | 1 |
| Sakizono, K | 1 |
| Minowa, K | 1 |
| Fukushima, S | 1 |
| Sugioka, N | 1 |
| Hashida, T | 1 |
| Ramanathan, K | 1 |
| Mohanty, B | 1 |
| Tang, S | 1 |
| MacLaren, G | 1 |
| Achino, C | 1 |
| Schweizer, R | 1 |
| Jacquemet, PL | 1 |
| Fellahi, JL | 1 |
| Jacquet-Lagrèze, M | 1 |
| Corcoran, JN | 1 |
| Jacoby, KJ | 1 |
| Olives, TD | 1 |
| Bangh, SA | 1 |
| Cole, JB | 1 |
| de Castro Brás, LE | 1 |
| Baccanale, CL | 1 |
| Eccleston, L | 1 |
| Sloan, T | 1 |
| St Antoine, JC | 1 |
| Verzwyvelt, SM | 1 |
| Pittman, P | 1 |
| O'Rourke, D | 1 |
| Meggs, WJ | 1 |
| Chudow, M | 1 |
| Ferguson, K | 1 |
| Karbek Akarca, F | 1 |
| Akceylan, E | 1 |
| Kıyan, S | 1 |
| Kao, R | 1 |
| Landry, Y | 1 |
| Chick, G | 1 |
| Leung, A | 1 |
| Morini, L | 1 |
| Moretti, M | 1 |
| Brandolini, F | 1 |
| Osculati, AMM | 1 |
| Groppi, A | 1 |
| Vignali, C | 1 |
| Raj, A | 1 |
| Panda, PK | 1 |
| Singh, SS | 1 |
| Nordmark Grass, J | 1 |
| Ahlner, J | 1 |
| Kugelberg, FC | 1 |
| Steinwall, J | 1 |
| Forsman, P | 1 |
| Lindeman, E | 1 |
| Christensen, MB | 1 |
| Petersen, KM | 1 |
| Bøgevig, S | 1 |
| Al-Gibouri, S | 1 |
| Jimenez-Solem, E | 1 |
| Dalhoff, KP | 1 |
| Petersen, TS | 1 |
| Andersen, JT | 1 |
| Enokiya, T | 1 |
| Iwashita, Y | 1 |
| Ilemura, K | 1 |
| Muraki, Y | 1 |
| Ishikura, K | 1 |
| Imai, H | 1 |
| Okuda, M | 1 |
| Bhatia, D | 1 |
| McDonald, MB | 1 |
| Tiyyagura, GK | 1 |
| Kondrich, J | 1 |
| Nasa, P | 1 |
| Singh, A | 1 |
| Juneja, D | 1 |
| Singh, O | 1 |
| Javeri, Y | 1 |
| Lai, F | 1 |
| Zhang, Y | 1 |
| Xie, DP | 1 |
| Li, F | 1 |
| Han, Y | 1 |
| Gérard, L | 1 |
| Galloy, AC | 1 |
| Capron, A | 1 |
| Hantson, P | 1 |
| Maskell, KF | 1 |
| Ferguson, NM | 1 |
| Bain, J | 1 |
| Wills, BK | 1 |
| Brunette-Lawrey, E | 1 |
| Croft, F | 1 |
| Reuter-Rice, KE | 1 |
| Peterson, BM | 1 |
| Smith, SW | 1 |
| Ferguson, KL | 1 |
| Hoffman, RS | 2 |
| Nelson, LS | 1 |
| Greller, HA | 1 |
| Azendour, H | 1 |
| Belyamani, L | 1 |
| Atmani, M | 1 |
| Balkhi, H | 1 |
| Haimeur, C | 1 |
| Varpula, T | 1 |
| Rapola, J | 1 |
| Sallisalmi, M | 1 |
| Kurola, J | 1 |
| Teker, MG | 1 |
| Ozdemir, H | 1 |
| Saidoglu, L | 1 |
| Erkalp, K | 1 |
| Başaranoğlu, G | 1 |
| Ideno, S | 1 |
| Nakada, T | 1 |
| Oiwa, T | 1 |
| Kobari, M | 1 |
| Yaguchi, A | 1 |
| Spiller, HA | 1 |
| Milliner, BA | 1 |
| Bosse, GM | 1 |
| Rizvi, I | 1 |
| Ahmad, A | 1 |
| Gupta, A | 1 |
| Zaman, S | 1 |
| Nimbalkar, SM | 1 |
| Patel, DV | 1 |
| Rasmussen, L | 1 |
| Husted, SE | 1 |
| Johnsen, SP | 1 |
| Saravu, K | 1 |
| Balasubramanian, R | 1 |
| Wood, DM | 1 |
| Wright, KD | 1 |
| Jones, AL | 1 |
| Dargan, PI | 1 |
| Sklerov, JH | 1 |
| Levine, B | 1 |
| Ingwersen, KM | 1 |
| Aronica-Pollack, PA | 1 |
| Fowler, D | 1 |
| Vogt, S | 1 |
| Mehlig, A | 1 |
| Hunziker, P | 1 |
| Scholer, A | 1 |
| Jung, J | 1 |
| González, AB | 1 |
| Weinmann, W | 1 |
| Marsch, S | 1 |
| Harris, NS | 1 |
| Poggenborg, RP | 1 |
| Videbaek, L | 1 |
| Jacobsen, IA | 1 |
| Kanagarajan, K | 1 |
| Marraffa, JM | 1 |
| Bouchard, NC | 1 |
| Krishnan, P | 1 |
| Stork, CM | 1 |
| Hung, YM | 1 |
| Olson, KR | 1 |
| Blankfield, RP | 1 |
| Iftikhar, I | 1 |
| Glickman, E | 1 |
| Harris, S | 1 |
| Ezidiegwu, C | 1 |
| Spektor, Z | 1 |
| Nasr, MR | 1 |
| Kelly, KC | 1 |
| Rosales, LG | 1 |
| Laine, K | 1 |
| Kivistö, KT | 1 |
| Laakso, I | 1 |
| Neuvonen, PJ | 1 |
| Adams, BD | 1 |
| Browne, WT | 1 |
| Feldman, R | 1 |
| Glińska-Serwin, M | 1 |
3 reviews available for amlodipine and Drug Overdose
| Article | Year |
|---|---|
Treatment of Amlodipine Intoxication with Intravenous Lipid Emulsion Therapy: A Case Report and Review of the Literature.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Female; Huma | 2017 |
Conventional and Unconventional Lifesaving Therapies in an Adolescent With Amlodipine Ingestion.
Topics: Adolescent; Amlodipine; Antidotes; Combined Modality Therapy; Critical Care; Drug Overdose; Emergenc | 2016 |
Amlodipine fatality in an infant with postmortem blood levels.
Topics: Amlodipine; Calcium Channel Blockers; Drug Overdose; Fatal Outcome; Humans; Infant; Male | 2012 |
1 trial available for amlodipine and Drug Overdose
| Article | Year |
|---|---|
Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration.
Topics: Adsorption; Adult; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Charcoal; Drug Overdo | 1997 |
43 other studies available for amlodipine and Drug Overdose
| Article | Year |
|---|---|
Refractory Shock from Amlodipine Overdose Overcomed with Hyperinsulinemia.
Topics: Aged; Amlodipine; Calcium Channel Blockers; COVID-19; Drug Overdose; Female; Humans; Hyperinsulinism | 2022 |
[Insulin/glucose therapy for the treatment of severe calcium channel blocker poisoning in pediatrics. Case report].
Topics: Amlodipine; Calcium Channel Blockers; Child; Drug Overdose; Glucose; Humans; Insulin; Suicide | 2021 |
Multi-organ dysfunction as a presentation of calcium channel blocker intoxication.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Female; Human | 2022 |
Use of extracorporeal membrane oxygenation in massive amlodipine overdose.
Topics: Albumins; Amlodipine; Antidotes; Calcium; Calcium Channel Blockers; Charcoal; Drug Overdose; Extraco | 2022 |
Re-elevation of serum amlodipine level after lipid emulsion therapy in an overdose case.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Humans; Lipid | 2019 |
Extracorporeal therapy for amlodipine poisoning.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Extracorporeal Membrane Oxygenation; Hem | 2020 |
Large underestimation of arterial pressure after vasodilator medication overdose.
Topics: Adolescent; Amlodipine; Arterial Pressure; Critical Care; Drug Overdose; Female; Femoral Artery; Hum | 2020 |
Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.
Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Bradycardia; Calcium Channel Blockers; Drug Admi | 2020 |
Efficacy of methylene blue in a murine model of amlodipine overdose.
Topics: Amlodipine; Animals; Cardiotoxicity; Disease Models, Animal; Drug Overdose; Methylene Blue; Mice; Mi | 2021 |
A Case of Severe, Refractory Hypotension After Amlodipine Overdose.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Overdose; Fatal Outcome; Humans; Hypotens | 2018 |
Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report.
Topics: Amlodipine; Blindness; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Female; | 2017 |
Two Fatal Cases Involving Cardiovascular Drugs Diltiazem and Amlodipine.
Topics: Amlodipine; Autopsy; Calcium Channel Blockers; Cause of Death; Chromatography, Liquid; Diltiazem; Dr | 2018 |
Amlodipine (150 mg) Poisoning: A Case Study.
Topics: Adolescent; Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Hypotension; Shock; | 2018 |
A case of massive metoprolol and amlodipine overdose with blood concentrations and survival following extracorporeal corporeal membrane oxygenation (ECMO).
Topics: Adult; Amlodipine; Drug Overdose; Extracorporeal Membrane Oxygenation; Female; Humans; Metoprolol; S | 2019 |
Outcomes following calcium channel blocker exposures reported to a poison information center.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Child; Child, Pres | 2018 |
Delayed elimination half-life of amlodipine in a case of drug overdose.
Topics: Aged; Amlodipine; Drug Overdose; Early Medical Intervention; Female; Humans; Time Factors | 2016 |
Index of suspicion. Case 1: Fatigue, weakness, body aches, and metabolic alkalosis in a 15-year-old boy. Case 2: Refractory hypotension, tachycardia, hyperglycemia, and metabolic acidosis in an afebrile teen.
Topics: Acidosis; Adolescent; Alkalosis; Amlodipine; Calcium Channel Blockers; Diagnosis, Differential; Drug | 2013 |
Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Charcoal; Dihydropyridines; Dru | 2014 |
Successful treatment with integrated Chinese and western medicine for severe overdose of amlodipine: A case report.
Topics: Adult; Aged; Amlodipine; Drug Overdose; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Ra | 2015 |
Mixed amlodipine/valsartan overdose treated by the molecular adsorbent recirculating system (MARS™).
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihyp | 2015 |
Survival After Cardiac Arrest: ECMO Rescue Therapy After Amlodipine and Metoprolol Overdose.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Amlodipine; Calcium Channel Blockers; Drug Overd | 2017 |
Losartan and amlodipine overdose-Case Report of a patient with anuric renal failure prior to the onset of hypotension.
Topics: Acute Kidney Injury; Amlodipine; Antihypertensive Agents; Anuria; Drug Overdose; Female; Humans; Hyp | 2016 |
Prolonged severe hypotension following combined amlodipine and valsartan ingestion.
Topics: Aged; Amlodipine; Antidotes; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Cardi | 2008 |
Severe amlodipine intoxication treated by hyperinsulinemia euglycemia therapy.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Drug Therapy, Combination; Epinephrine; | 2010 |
Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.
Topics: Acidosis, Lactic; Amlodipine; Calcium Channel Blockers; Cardiotonic Agents; Coma; Drug Overdose; Ech | 2009 |
Levosimendan as a rescue adjunct in amlodipine intoxication--a case report.
Topics: Adolescent; Adrenergic alpha-Agonists; Amlodipine; Antidotes; Calcium Channel Blockers; Calcium Chlo | 2010 |
[Case of olmesartan and amlodipine intoxication].
Topics: Acid-Base Imbalance; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Calcium Gluconate; Drug Ov | 2011 |
Life-threatening calcium channel blocker overdose and its management.
Topics: Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Hypoglycemic Agents; Insulin; R | 2012 |
Near fatal case of amlodipine poisoning in an infant.
Topics: Amlodipine; Calcium Channel Blockers; Drug Overdose; Glucose; Humans; Hypotension; Infant; Infusions | 2013 |
Severe intoxication after an intentional overdose of amlodipine.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Insulin | 2003 |
Pharmaceutical drug overdose case reports. From the World Literature.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amlodipine; Child, Preschool; Diphenhydramine; Dizocilpine M | 2003 |
Near-fatal amlodipine poisoning.
Topics: Adult; Amlodipine; Antidotes; Combined Modality Therapy; Drug Overdose; Follow-Up Studies; Gastric L | 2004 |
Metaraminol (Aramine) in the management of a significant amlodipine overdose.
Topics: Adrenergic alpha-Agonists; Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Hemodynamics; | 2005 |
Two cases of fatal amlodipine overdose.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Overdose; Female; G | 2006 |
Survival of severe amlodipine intoxication due to medical intensive care.
Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Chlorthalidone | 2006 |
Case records of the Massachusetts General Hospital. Case 24-2006. A 40-year-old woman with hypotension after an overdose of amlodipine.
Topics: Adult; Amlodipine; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Combined Modality Therapy; | 2006 |
A case of amlodipine overdose.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Overdose; Humans; Male; Suicide, A | 2006 |
The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose.
Topics: Adult; Amlodipine; Antidotes; Blood Pressure; Calcium Channel Blockers; Diazepam; Diltiazem; Drug Ov | 2007 |
Acute amlodipine overdose treated by high dose intravenous calcium in a patient with severe renal insufficiency.
Topics: Acute Kidney Injury; Adult; Amlodipine; Antidotes; Blood Pressure; Calcium; Calcium Channel Blockers | 2007 |
Temperature and blood pressure following amlodipine overdose.
Topics: Adult; Amlodipine; Blood Pressure; Body Temperature Regulation; Drug Overdose; Female; Humans; Suici | 2008 |
A case report on the role of plasma exchange in the management of a massive amlodipine besylate intoxication.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Overdose; Female; Humans; Plasma Exchange; Suicide | 2008 |
Amlodipine overdose causes prolonged calcium channel blocker toxicity.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Drug Overdose; Emergency Treatment; Hemodynamics; Humans | 1998 |
[Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine].
Topics: Adult; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Overdose; Female; Heart F | 2001 |