amlodipine has been researched along with Dementia in 4 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An amlodipine-based BP regimen reduced the long-term incidence of stroke compared with an atenolol-based regimen but had no measurable effect on dementia." | 4.02 | Long-Term Incidence of Stroke and Dementia in ASCOT. ( Godec, T; Gupta, AK; Mackay, J; Rostamian, S; Sever, PS; Whitehouse, A; Whiteley, WN, 2021) |
| "Patients with hypertension have a higher risk of developing stroke as well as experiencing a decline in cognitive functions and dementia." | 1.91 | In the prevention of dementia, the focus should be on early and consistent treatment of hypertension. ( Souček, M, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colbourne, L | 1 |
| Harrison, PJ | 1 |
| Kerkhofs, D | 1 |
| Helgers, R | 1 |
| Hermes, D | 1 |
| Steinbusch, HPJ | 1 |
| Van Essen, H | 1 |
| Leenders, P | 1 |
| Prickaerts, J | 1 |
| Staals, J | 1 |
| Biessen, EA | 1 |
| Van Oostenbrugge, RJ | 1 |
| Foulquier, S | 1 |
| Souček, M | 1 |
| Whiteley, WN | 1 |
| Gupta, AK | 1 |
| Godec, T | 1 |
| Rostamian, S | 1 |
| Whitehouse, A | 1 |
| Mackay, J | 1 |
| Sever, PS | 1 |
4 other studies available for amlodipine and Dementia
| Article | Year |
|---|---|
Brain-penetrant calcium channel blockers are associated with a reduced incidence of neuropsychiatric disorders.
Topics: Amlodipine; Brain; Calcium Channel Blockers; Dementia; Depressive Disorder, Major; Female; Humans; H | 2022 |
Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Blockers; Dem | 2023 |
In the prevention of dementia, the focus should be on early and consistent treatment of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Dementia; Drug Combinations; Humans; Hypertensi | 2023 |
Long-Term Incidence of Stroke and Dementia in ASCOT.
Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atenolol; Atorvastatin; Cholest | 2021 |